Cns tumors

Lecture Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Glioblastoma Cerebrum

What is a brain tumor? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Glioma : high grade (IV)

Brain Tumors Patho-physiology ,[object Object],[object Object],[object Object],[object Object],[object Object]

Morphologic Classification of CNS tumors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Histologic Classification of Glial Tumors (World Health Organization 2000) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Astrocytoma-Lowgrade (2) fibrillary

CNS Tumor Classification: by site of origin( Pathologic classification) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Primary brain tumors: by Cell types (Histologic Classification) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Glioblastoma Multiforme Palisading B.V Necrosis

POPULATION WITH BRAIN TUMORS! ,[object Object],[object Object],[object Object],[object Object],[object Object]

Normal Anatomy of Brain (MRI) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Glioblastoma MF Adults Children

CNS Tumors Incidence: General Features ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Adults Children ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Presentation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Clinical Presentation ,[object Object],[object Object],[object Object]

Clinical Presentation ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Localised

Gliomas: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Gliomas: Glioblastoma Multiforme (GBM): ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Gliomas:Prognosis for Glioblastoma multiforme ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Gliomas: Ependymal Tumors MRI image shows an ependymoma (arrow) in the right lateral ventricle.

Non-glial tumors ,[object Object],[object Object],[object Object]

Non-glial tumors:Medulloblastoma Pediatric Brain Tumors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Medulloblastoma Pediatric Brain Tumors ,[object Object],Posterior fossa Sagittal Axial

Non-glial tumors: Meningioma ,[object Object],[object Object],[object Object],Meninges

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Patho-biology of CNS tumors

Diagnosis ,[object Object],[object Object],[object Object],MRI preferred  sensitivity  resolution  three planer views ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

CNS Tumor Treatment modalities ,[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Surgical Resection

[object Object],[object Object],Surgical Resection

[object Object],[object Object],Surgical Resection ,[object Object],[object Object]

The past*-Whole brain irradiation! Radiation Therapy *2 brain tumors

The present- Stereotactic Radiosurgery ,[object Object],[object Object],[object Object],[object Object]

Gamma Knife ,[object Object],[object Object]

In Gamma Knife ,[object Object],[object Object],[object Object]

Linear Accelerator Systems ,[object Object],[object Object],[object Object],[object Object],[object Object]

In Linear Accelerator system (CyberKnife) ,[object Object],[object Object],[object Object]

Radiosurgery for Brain Metastasis ,[object Object],[object Object],[object Object],[object Object]

Non-Surgical Treatments of Brain Tumors ,[object Object],[object Object],[object Object],[object Object],[object Object]

Passive immunotherapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Anti-angiogenic Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Vascular Endothelial Growth Factor Pathway Inhibitors ,[object Object],[object Object]

Non-Vascular Endothelial Growth Factor Pathway Inhibitors ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object]

Chemotherapy ,[object Object],[object Object]

Cytotoxic Chemotherapy ,[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object]

Secondary-Brain Tumor ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

CNS tumor prevention ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Total Recall- What you need to know ,[object Object],[object Object],[object Object],[object Object]

Cns tumors

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Cns tumors