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PLEURAL DISEASES
M.Thulasiraman.,RN,RM & RT
Institute of Critical Care Medicine,
Royal Care Super Speciality Hospital.
ANATOMY
• The pleura is the serous membrane that covers
the lung parenchyma (visceral pleura) , the
mediastinum, the diaphragm, and the rib cage
(parietal pleura).
• visceral pleura: blood supply from low- pressure
pulmonary circulation, and has no sensory
nerves
• parietal pleura: from the systemic circulation
and contains sensory nerves
ANATOMY OF PLURA
PHYSIOLOGY
The two layers of the pleura are separated
by a virtual cavity, which is lubricated by 5 to
10 mL of fluid, facilitates lung expansion,
and helps maintain lung inflation by coupling
the lungs with the chest wall.
CLASSIFICATION
PLEURAL EFFUSION
Pleural effusion, sometimes referred to as “water on the
lungs,” is the build-up of excess fluid between the layers of the pleura
outside the lungs. The pleura are thin membranes that line the lungs
and the inside of the chest cavity and act to lubricate and facilitate
breathing.
ETIOLOGY
• Congestive heart failure
• Cirrhosis
• Peritoneal dialysis
• Nephrotic syndrome
• Superior vena cava obstruction
• Myxedema
• Pulmonary thromboemboli
Transudative Pleural Effusions
• Infectious diseases
Tuberculosis, Bacterial infections, Fungal,
Viral, Parasitic
• Neoplasms
• Pulmonary thromboembolization
• Gastrointestinal disease
Pancreatitis, Esophageal perforation,
Intra-abdominal abscesses
• Collagen vascular diseases
Rheumatoid arthritis, Lupus erythematosus
ETIOLOGY
Exudative Pleural Effusions
• Drug-induced pleural disease
Nitrofurantoin, Amiodarone
• Asbestos exposure
• Chylothorax
• Hemothorax
• Postsurgical
• Sarcoidosis
• Uremic pleuritis
• Yellow nail syndrome
ETIOLOGY
LIGHT'S CRITERIA
CLINICAL MANIFESTATION
INVESTIGATIONS
x-ray
Ultrasound image of the left hemithorax
USG
Computed tomography: Bilateral pleural effusions
are present as a result of pneumonia
CT Scan
PLEURAL EFFUSION.: A, Blood-stained pleural aspirate. This patient
had pleural metastases from carcinoma of the breast.
B, Chylous pleural effusion. This patient had bronchial carcinoma that
had invaded and obstructed the thoracic duct.
C, Pleural transudate. This pale effusion is typically found in patients
with heart failure or other causes of generalized edema.
EMPYEMA
EMPYEMA
• Is pus in the pleural space
Etiology:
• Empyema is always secondary to infection
in a neighbouring structure, usually the
lung. The principal infections liable to
produce empyema are the bacterial
pneumonias and TB.
• Pathophysiology:
parapneumonic pleural effusion
exudative stage
↓
fibropurulent stage
↓
organization stage
Clinical Features
Symptoms:
• Pyrexia, usually high and remittent
• Rigors, sweating, malaise and weight loss
• Pleural pain
• Breathlessness
• Cough and sputum usually because of
underlying lung disease;
• Copious purulent sputum (bronchopleural
fistula)
Signs:
• Clinical signs of fluid in the pleural space
• Intercostal tenderness
Treatment
• Antibiotics OR anti tubercular drugs
• Intercostal tube drainage
• Decortication if gross thickening of the
visceral pleura has developed and is
preventing re-expansion of the lung
THANKS

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Pleural disease (Pleural effusion & Empyme)

  • 1. PLEURAL DISEASES M.Thulasiraman.,RN,RM & RT Institute of Critical Care Medicine, Royal Care Super Speciality Hospital.
  • 2. ANATOMY • The pleura is the serous membrane that covers the lung parenchyma (visceral pleura) , the mediastinum, the diaphragm, and the rib cage (parietal pleura). • visceral pleura: blood supply from low- pressure pulmonary circulation, and has no sensory nerves • parietal pleura: from the systemic circulation and contains sensory nerves
  • 4. PHYSIOLOGY The two layers of the pleura are separated by a virtual cavity, which is lubricated by 5 to 10 mL of fluid, facilitates lung expansion, and helps maintain lung inflation by coupling the lungs with the chest wall.
  • 6. PLEURAL EFFUSION Pleural effusion, sometimes referred to as “water on the lungs,” is the build-up of excess fluid between the layers of the pleura outside the lungs. The pleura are thin membranes that line the lungs and the inside of the chest cavity and act to lubricate and facilitate breathing.
  • 7.
  • 8. ETIOLOGY • Congestive heart failure • Cirrhosis • Peritoneal dialysis • Nephrotic syndrome • Superior vena cava obstruction • Myxedema • Pulmonary thromboemboli Transudative Pleural Effusions
  • 9. • Infectious diseases Tuberculosis, Bacterial infections, Fungal, Viral, Parasitic • Neoplasms • Pulmonary thromboembolization • Gastrointestinal disease Pancreatitis, Esophageal perforation, Intra-abdominal abscesses • Collagen vascular diseases Rheumatoid arthritis, Lupus erythematosus ETIOLOGY Exudative Pleural Effusions
  • 10. • Drug-induced pleural disease Nitrofurantoin, Amiodarone • Asbestos exposure • Chylothorax • Hemothorax • Postsurgical • Sarcoidosis • Uremic pleuritis • Yellow nail syndrome ETIOLOGY
  • 14. x-ray
  • 15. Ultrasound image of the left hemithorax USG
  • 16. Computed tomography: Bilateral pleural effusions are present as a result of pneumonia CT Scan
  • 17. PLEURAL EFFUSION.: A, Blood-stained pleural aspirate. This patient had pleural metastases from carcinoma of the breast. B, Chylous pleural effusion. This patient had bronchial carcinoma that had invaded and obstructed the thoracic duct. C, Pleural transudate. This pale effusion is typically found in patients with heart failure or other causes of generalized edema.
  • 19. EMPYEMA • Is pus in the pleural space Etiology: • Empyema is always secondary to infection in a neighbouring structure, usually the lung. The principal infections liable to produce empyema are the bacterial pneumonias and TB.
  • 20. • Pathophysiology: parapneumonic pleural effusion exudative stage ↓ fibropurulent stage ↓ organization stage
  • 21. Clinical Features Symptoms: • Pyrexia, usually high and remittent • Rigors, sweating, malaise and weight loss • Pleural pain • Breathlessness • Cough and sputum usually because of underlying lung disease; • Copious purulent sputum (bronchopleural fistula)
  • 22. Signs: • Clinical signs of fluid in the pleural space • Intercostal tenderness
  • 23. Treatment • Antibiotics OR anti tubercular drugs • Intercostal tube drainage • Decortication if gross thickening of the visceral pleura has developed and is preventing re-expansion of the lung