Yellow Fever Vaccination is a serious viral infection that’s usually spread by a type of daytime biting mosquito known as the Aedes aegypti. It can be prevented with a vaccination.

1. Yellow Fever Vaccination is a serious viral infection that’s
usually spread by a type of daytime biting mosquito known
as the Aedes aegypti. It can be prevented with a vaccination.
Yellow fever mainly occurs in sub-Saharan Africa (countries
to the south of the Sahara desert), South America (especially
the Amazon)and in parts of the Caribbean.
Yellow fever can be fatal. About 8% of people who get yellow
fever die from it.
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2. Under regulations set out by the World Health Organization (WHO), anyone traveling to a
country or area where the Aedes aegypti mosquito is found must have the vaccine or have an
International Certificate of Vaccination or Prophylaxis (ICVP). You can find a list of all the
countries that require you to have an ICVP in the WHO International travel and health guide. You
can also search the country information on NaTHNaC to find out whether the places you are
visiting require an ICVP.
If you have been traveling in an “at-risk” area during the past month, it is a good idea to carry your
certificate with you. This will help avoid potential problems with immigration. It is possible for
travelers without a valid yellow fever vaccination certificate to be vaccinated and held in isolation
forup to10 days. An ICVP isnot required forentry into the UK.
If you lose your certificate, you may be able to get another one reissued as long as you have
details ofthe vaccination batch number andthe date you had the vaccination.
Always consult staff at a designated vaccination centre if you are planning to travel to an area
where there is a risk of getting yellow fever. If you tell them where you are traveling to, they will
be able to advise you about whether you need to be vaccinated against yellow fever and whether
you need an ICVP.

3. •People who should not have the yellow fever vaccination include: Babies under nine months of age – babies who are six
to ninemonths old should only be vaccinated if the risk of getting yellow fever during travel is unavoidable
•Pregnant women –unless the risk of yellow fever is unavoidable
•Breastfeeding women – unless the risk of yellow fever is unavoidable
•People whose immune systems are lowered (immunosuppressed) – such as people with HIV and those receiving
chemotherapy orradiotherapy
•People who areallergic to eggs – the vaccine contains small amounts of egg white protein, albumin.
•People who have hada severe allergic reaction (anaphylaxis) to a previous dose of theyellow fever vaccine
•People who areallergic to any of the ingredients in the vaccine(including eggs)
•People who have a condition that affects the thymus gland (part of your immune system that is located in your upper
chest)
•People who are currently very unwell (such as with a high fever) – this is to avoid confusing the diagnosis of your
currentillness with any side effects from the vaccine
•Yellow fever naïve travellers – those who have not been previously exposed to the vaccine who are 60 years of age or
over should be individually assessed by the travel doctor ornurse.

4. After having the yellow fever vaccine, 10-30% of people will have mild side effects such as: headache,
muscle pain,sorenessattheinjection siteandmildfever
Reactions at the injection site usually occur one to five days after being vaccinated, although other side
effectsmaylastforuptotwoweeks.
An allergic reaction to the vaccine occurs in one case out of every 130,000 doses of the vaccine that are
given. Yellow fever vaccine-associatedneurologicaldisease(YEL-AND)
Rarely, the yellow fever vaccine is associated with a neurological condition known as yellow fever vaccine-
associated neurological disease (YEL-AND). Neurological means that it affects the nerves and the nervous
system,including thebrainandspinalcord.
YEL-AND occurs in around four cases out of every 1 million doses given. However, for people who are 60
years of age or over and yellow fever vaccine naïve, the incidence of YEL-AND increases to around one in
every 50,000.Thisneeds tobebalancedagainsttheriskofacquiringthedisease.

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