Over the last 12 months, EudraVigilance has identified over 30,000 individual cases of reactions to TOZINAMERAN, with the number of reported cases from EEA countries trending upwards and exceeding those from non-EEA countries. The dashboard displays the total number of cases over time and broken down by country and reaction type to monitor safety signals. Users are directed to key considerations on interpreting the results on the ADR reports website.

1. 2/13/2021 Oracle BI Interactive Dashboards - DAP
https://dap.ema.europa.eu/analytics/saw.dll?PortalPages 1/2
Number of Individual Cases Number of Individual Cases by EEA countries Number of Individual Cases By Reaction Gro
Number of individual cases identified in EudraVigilance received over the last 12 months and overall for TOZINAMERAN (up to 13/0
Number of Individual Cases received over time
Dec 2020 Jan 2021
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Trend EEA Cases Non-EEA Cases
For the interpretation of the results, please refer to the key considerations at www.adrreports.eu
Number of Individual Cases received over time

2. 2/13/2021 Oracle BI Interactive Dashboards - DAP
https://dap.ema.europa.eu/analytics/saw.dll?PortalPages 2/2