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FFR using 4Fr catheters: Can
Slender Technique Work Here?
Ian C Gilchrist, MD, FACC, FSCAI
Professor of Medicine
Penn State’s Hershey Medical Center
Heart & Vascular Institute
Hershey, PA
USA
icg2018
4 French Feasibility
Yadav, Gilchrist. JACC 2014;64(11_S)
Pop Test
Pulse-Duplicator
Area 4-F catheter = 3.14 mm2
Area 0.014” wire = 0.10 mm2
Mean difference = 0.006 [-0.052-0.064]
Legalery, et al. Am J Cardiol 2003;91:1075–1078
4F Diagnostic vs 7F Guide FFR
∆(4FFFR-7FrFFR)
µFFR
icg2018
4F vs 6F Diagnostic Catheter FFR
61 patients
4F FFR
FFR 0.70-0.90
Cut point 0.80
6F FFR
Paired Comparison
Moriyama N, et al. COFFEE Trial. JACC I 2018;;11:412-14
icg2018
Example: Taking it a Down a Notch
50 year old woman with recurrent atypical pain
RCA stent last year via left radial out of town
Stress test was equivocal
Small, light framed woman
Definitely wants a wrist approach again
Right radial
5F sheath
Option for intervention
icg 2017
icg2018
0.035” wire stopped at sheath
Right forearm angiogram via sheath
High origin of radial from brachial artery
High-branching radial
& spasm
icg2018
Switched to 4F
LCA- 4F JL3.5 RCA- 4F JR4.0
icg2018
Not Sure of RCA at Stent
stent
Options?
1. Go down under (groin)?
2. Contalateral radial?
3. Ulnars?
icg 2017
icg2018
FFR- 4 French Multipurpose
icg 2017
icg2018
General Coronary Set-Up
Hydrostatic transducer (Ao)
Electronic transducer (Co)
Computer
FFR, iFR, etc
Flushed Catheter
Clean Signal
No Catheter Damping
Wire
Normalized
Calibrated
Positioned
icg2018
Effects of Catheters in Different
Coronary Ostia
Toth, J Am Coll Cardiol. 2016;68(7):742-753.
5-F
6-F
7-F
4-F Catheter
Area 4-F catheter = 3.14 mm2
Area 0.014” wire = 0.10 mm2
4F
0.014” wire
icg2018
Lumen
Longitudinal Effects
THROMBIN CONTRAST
WHAT HAPPENS TO THE
PULSE WAVEFORM?
Ideal pressure wave
Ideal pressure wave
central obstacle
Lumen1
Lumen2
icg2018
4F Catheter Characteristics
Diagnostic only in US
Can’t directly do PCI if needed
Interface between wire & catheter
wall may add friction
Thermo-stability poor
icg2018
4-F Technique
Less forgiving than larger French
Use fresh catheter & rapidly introduce wire
Meticulous FFR/iFR technique needed
• Confirm lumen is well flushed
• Transducer or catheter is not-damped
• Dicrotic notches on tracing?
Lack of immediate interventional
capacity may temper patient choice
icg2018
Improvements Needed
Better understanding of wire/internal catheter
interface to improve coeffiecent of friction
4-F guides or equivalent (FFR catheters?)
Potential for smaller catheters if sensor also
placed on distal catheter
Goal: Use of the smallest diameter access into the radial artery required
for diagnosis will maximize long-term radial artery function
icg2018
Thank you
icg1@psu.edu
@RADIAL_icg

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PCI & AimRadial 2018 | FFR using 4Fr catheters: Can Slender Technique Work Here? - Ian C Gilchrist

  • 1. FFR using 4Fr catheters: Can Slender Technique Work Here? Ian C Gilchrist, MD, FACC, FSCAI Professor of Medicine Penn State’s Hershey Medical Center Heart & Vascular Institute Hershey, PA USA
  • 2. icg2018 4 French Feasibility Yadav, Gilchrist. JACC 2014;64(11_S) Pop Test Pulse-Duplicator Area 4-F catheter = 3.14 mm2 Area 0.014” wire = 0.10 mm2 Mean difference = 0.006 [-0.052-0.064] Legalery, et al. Am J Cardiol 2003;91:1075–1078 4F Diagnostic vs 7F Guide FFR ∆(4FFFR-7FrFFR) µFFR
  • 3. icg2018 4F vs 6F Diagnostic Catheter FFR 61 patients 4F FFR FFR 0.70-0.90 Cut point 0.80 6F FFR Paired Comparison Moriyama N, et al. COFFEE Trial. JACC I 2018;;11:412-14
  • 4. icg2018 Example: Taking it a Down a Notch 50 year old woman with recurrent atypical pain RCA stent last year via left radial out of town Stress test was equivocal Small, light framed woman Definitely wants a wrist approach again Right radial 5F sheath Option for intervention icg 2017
  • 5. icg2018 0.035” wire stopped at sheath Right forearm angiogram via sheath High origin of radial from brachial artery High-branching radial & spasm
  • 6. icg2018 Switched to 4F LCA- 4F JL3.5 RCA- 4F JR4.0
  • 7. icg2018 Not Sure of RCA at Stent stent Options? 1. Go down under (groin)? 2. Contalateral radial? 3. Ulnars? icg 2017
  • 8. icg2018 FFR- 4 French Multipurpose icg 2017
  • 9. icg2018 General Coronary Set-Up Hydrostatic transducer (Ao) Electronic transducer (Co) Computer FFR, iFR, etc Flushed Catheter Clean Signal No Catheter Damping Wire Normalized Calibrated Positioned
  • 10. icg2018 Effects of Catheters in Different Coronary Ostia Toth, J Am Coll Cardiol. 2016;68(7):742-753. 5-F 6-F 7-F 4-F Catheter Area 4-F catheter = 3.14 mm2 Area 0.014” wire = 0.10 mm2 4F 0.014” wire
  • 11. icg2018 Lumen Longitudinal Effects THROMBIN CONTRAST WHAT HAPPENS TO THE PULSE WAVEFORM? Ideal pressure wave Ideal pressure wave central obstacle Lumen1 Lumen2
  • 12. icg2018 4F Catheter Characteristics Diagnostic only in US Can’t directly do PCI if needed Interface between wire & catheter wall may add friction Thermo-stability poor
  • 13. icg2018 4-F Technique Less forgiving than larger French Use fresh catheter & rapidly introduce wire Meticulous FFR/iFR technique needed • Confirm lumen is well flushed • Transducer or catheter is not-damped • Dicrotic notches on tracing? Lack of immediate interventional capacity may temper patient choice
  • 14. icg2018 Improvements Needed Better understanding of wire/internal catheter interface to improve coeffiecent of friction 4-F guides or equivalent (FFR catheters?) Potential for smaller catheters if sensor also placed on distal catheter Goal: Use of the smallest diameter access into the radial artery required for diagnosis will maximize long-term radial artery function