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Bellringer
List an example of an acid or base you
are familiar with in everyday life.
What do you know about the pH scale?
Agenda
 Collection Time
 Book Project & Macromolecule notes
 Candy Molecules lab
 Quick Experiment: Milk and Vinegar
 Guided Notes: pH & the Effect on Protein
 Compare Acids and Bases
 Review the use of pH scale
 Describe how changes in pH affect proteins
Properties of Acids
Sour taste
Corrosive to metals
Burns the Skin
Examples of Acids
Acetic Acid in Vinegar
Citric Acid in Oranges and
Lemons
Hydrochloric Acid dissolves
food in your stomach
Properties of Bases
Bitter Taste
Feel “Soapy”
Will irritate your skin
Examples of Bases
Milk of Magnesia
Bleach
Many Soaps
Acid/Base Chemistry
Acids release Hydrogen ions [H+]
when mixed with water.
Bases absorb Hydrogen ions [H+]
when mixed with water.
Neutralizations
Since Acids produce [H+] and Bases
absorb [H+], it is possible for acids
and bases to cancel one another.
When acids and bases cancel out it
is called Neutralizing
pH Scale
The strength of Acids and Bases
is measured using the pH scale
Scale goes from 0 to 14
 ACIDS = below 7
 NEUTRAL = exactly 7
 BASES = above 7
pH and Strength
The further an acid or base is from 7,
the stronger it is.
Examples
 Lemon Juice (2.0) is a stronger acid than Beer
(4.0) because a pH of 2 is farther from 7.
 Ammonia (11.0) is a stronger base than Baking
Soda (8.3) because a pH of 11 is farther from 7.
BrainPOP: Acid/Base
Protein Folding
Proteins are long chains of amino acids.
These chains bend and fold into a certain
shape that allows them to perform their job.
The shape of the protein is held together by
bonds between amino acids on different parts
of the chain.
Protein Structure Video Clip
How Acids Denature Proteins
 Acids destroy proteins by “denaturing” them. This
means that the protein gets unwrapped and the
shape is destroyed.
 Acids can unwind proteins because the H+
[Hydrogen ions] interfere with the bonds that hold
the protein together.
 For this reason, it is important for living things to
maintain a consistent pH level in bodily fluid. For
example, human blood must stay at a pH of 7.4
H+
H+
H+
H+
H+
Explain what caused the milk to curdle. . .
Assignments
12 Review Questions
Using pH to identify liquids
Students should complete their
Quarterly Assessment if not finished
yesterday.

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Biochem 3: pH & proteins

  • 1. Bellringer List an example of an acid or base you are familiar with in everyday life. What do you know about the pH scale?
  • 2. Agenda  Collection Time  Book Project & Macromolecule notes  Candy Molecules lab  Quick Experiment: Milk and Vinegar  Guided Notes: pH & the Effect on Protein  Compare Acids and Bases  Review the use of pH scale  Describe how changes in pH affect proteins
  • 3. Properties of Acids Sour taste Corrosive to metals Burns the Skin
  • 4. Examples of Acids Acetic Acid in Vinegar Citric Acid in Oranges and Lemons Hydrochloric Acid dissolves food in your stomach
  • 5. Properties of Bases Bitter Taste Feel “Soapy” Will irritate your skin
  • 6. Examples of Bases Milk of Magnesia Bleach Many Soaps
  • 7. Acid/Base Chemistry Acids release Hydrogen ions [H+] when mixed with water. Bases absorb Hydrogen ions [H+] when mixed with water.
  • 8. Neutralizations Since Acids produce [H+] and Bases absorb [H+], it is possible for acids and bases to cancel one another. When acids and bases cancel out it is called Neutralizing
  • 9. pH Scale The strength of Acids and Bases is measured using the pH scale Scale goes from 0 to 14  ACIDS = below 7  NEUTRAL = exactly 7  BASES = above 7
  • 10. pH and Strength The further an acid or base is from 7, the stronger it is. Examples  Lemon Juice (2.0) is a stronger acid than Beer (4.0) because a pH of 2 is farther from 7.  Ammonia (11.0) is a stronger base than Baking Soda (8.3) because a pH of 11 is farther from 7.
  • 12. Protein Folding Proteins are long chains of amino acids. These chains bend and fold into a certain shape that allows them to perform their job. The shape of the protein is held together by bonds between amino acids on different parts of the chain.
  • 13.
  • 15. How Acids Denature Proteins  Acids destroy proteins by “denaturing” them. This means that the protein gets unwrapped and the shape is destroyed.  Acids can unwind proteins because the H+ [Hydrogen ions] interfere with the bonds that hold the protein together.  For this reason, it is important for living things to maintain a consistent pH level in bodily fluid. For example, human blood must stay at a pH of 7.4
  • 17. Explain what caused the milk to curdle. . .
  • 18. Assignments 12 Review Questions Using pH to identify liquids Students should complete their Quarterly Assessment if not finished yesterday.