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Biochem 3: pH & proteins
1. Bellringer
List an example of an acid or base you
are familiar with in everyday life.
What do you know about the pH scale?
2. Agenda
Collection Time
Book Project & Macromolecule notes
Candy Molecules lab
Quick Experiment: Milk and Vinegar
Guided Notes: pH & the Effect on Protein
Compare Acids and Bases
Review the use of pH scale
Describe how changes in pH affect proteins
8. Neutralizations
Since Acids produce [H+] and Bases
absorb [H+], it is possible for acids
and bases to cancel one another.
When acids and bases cancel out it
is called Neutralizing
9. pH Scale
The strength of Acids and Bases
is measured using the pH scale
Scale goes from 0 to 14
ACIDS = below 7
NEUTRAL = exactly 7
BASES = above 7
10. pH and Strength
The further an acid or base is from 7,
the stronger it is.
Examples
Lemon Juice (2.0) is a stronger acid than Beer
(4.0) because a pH of 2 is farther from 7.
Ammonia (11.0) is a stronger base than Baking
Soda (8.3) because a pH of 11 is farther from 7.
12. Protein Folding
Proteins are long chains of amino acids.
These chains bend and fold into a certain
shape that allows them to perform their job.
The shape of the protein is held together by
bonds between amino acids on different parts
of the chain.
15. How Acids Denature Proteins
Acids destroy proteins by “denaturing” them. This
means that the protein gets unwrapped and the
shape is destroyed.
Acids can unwind proteins because the H+
[Hydrogen ions] interfere with the bonds that hold
the protein together.
For this reason, it is important for living things to
maintain a consistent pH level in bodily fluid. For
example, human blood must stay at a pH of 7.4