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Chapter 20 QBA Miguel A. Castro R.


                 Carbohydrates and
                 Lipids
Carbohydrates and Living Systems

A monosaccharide (C6H12O6) is a simple sugar
 that is the basic subunit of a carbohydrate.

A disaccharide (C12H22O11) is a sugar formed from
 two monosaccharides.

Apolysaccharide is one of the carbohydrates
 made up of long chains of simple sugars.
Carbohydrates and Living Systems

 Polysaccharides   include starch, glycogen,
  and cellulose.
 Potatoes have a lot of starch, the
  polysaccharide that plants use for storing
  energy.
 Many animals make use of a similar energy-
  storage carbohydrate called glycogen.
 Cellulose is the polysaccharide that most
  plants use to give their structures rigidity.
To a chemist, sugar is the name given to all
 monosaccharides and disaccharides.
Each molecule of sucrose, the sugar used to
 sweeten food, is made up of a glucose and a
 fructose unit.
Carbohydrates

  Just  as two monosaccharides combine
   to form a disaccharide, many can
   combine to form a long chain called a
   polysaccharide.
  Polysaccharides may be represented
   by the general formula below.

—O—(C6H10O4)—O—(C6H10O4)—O—(C6H10O4)...
Carbohydrates

 Polymerization   is a series of synthesis
 reactions that link many monomers
 together to make a very large, chainlike
 molecule.

 Polysaccharides  and other large,
 chainlike molecules found in living
 things are called biological polymers.
Carbohydrate Reactions

 Polysaccharides are changed back to
  sugars during hydrolysis reactions.

 In these reactions, the decomposition
  of a biological polymer takes place
  along with the breakdown of a water
  molecule, as shown in the equation
  below.
Lipids

A lipid is a type of biochemical that
 does not dissolve in water, including
 fats and steroids.

 Lipids
       generally can have a polar,
 hydrophilic region at one end of the
 molecule. For example, oleic acid,
 shown below is found in the fat of some
 animals.
Lipids

 Lipids are used in animals for energy storage
  as fats.

 Cell
     membranes are made up of lipids called
  phospholipids.

 Steroids, such as cholesterol, are lipids used
  for chemical signaling.

 Waxes, such as those found in candles and
  beeswax are also lipids.
Chapter 20




    Proteins
Amino Acids and Proteins

A  protein is a biological polymer that is
  made up of nitrogen, carbon, hydrogen,
  oxygen, and sometimes other elements.
 Our bodies are mostly made out of proteins.
 All proteins are biological polymers made up
  of amino acid monomers.
 An amino acid is any one of 20 different
  organic molecules that contain a carboxyl
  and an amino group and that combine to
  form proteins.
Amino Acids and Proteins

 Amino   refers to the −NH2 group of
 atoms.

 Acid
    refers to the carboxylic acid group,
 −COOH.

 Thereare 20 natural amino acids. All
 20 have the same basic structure.
The R represents a side chain.
Amino Acids and Proteins

 Thereaction by which proteins are made
 from amino acids is similar to the
 condensation of carbohydrates.

 Thebiological polymer that forms during the
 condensation of amino acids is called a
 polypeptide.

 The link that joins the N and C atoms of two
 different amino acids is called a peptide
 bond.
Amino Acids and Proteins

 The sequence of amino acids—the primary
 structure—helps dictate the protein’s final
 shape.

A substitution of just one amino acid in the
 polypeptide sequence can have major effects
 on the final shape of the protein.

A hereditary blood cell disease called sickle
 cell anemia gives one example of the
 importance of amino-acid sequence.
Enzymes

 Anenzyme is a type of protein that
 speeds up metabolic reactions in plant
 and animals without being permanently
 changed or destroyed.

 Almost  all of the chemical reactions in
 living systems take place with the help
 of enzymes.
Enzymes
 Enzymes   work like a lock and key. That is,
  only an enzyme of a specific shape can fit
  the reactants of the reaction that it is
  catalyzing.

 Only a small part of the enzyme’s surface,
  known as the active site, is believed to make
  the enzyme active.

 In reactions that use an enzyme, the reactant
  is called a substrate.
Chapter 20




    Nucleic Acids
Information Storage

 Allhereditary information is stored
  chemically in compounds called nucleic
  acids.

 Nucleic  acids are an organic
  compound, either RNA or DNA, whose
  molecules are made up of one or two
  chains of nucleotides and carry genetic
  information.
Nucleic-Acid Structure

•   Like polysaccharides and
    polypeptides, nucleic acids are
    biological polymers. They are
    made up of monomers called
    nucleotides.
Information Storage

 The nucleic acid DNA, or deoxyribonucleic acid,
 is the material that contains the information that
 determines inherited characteristics.

 The sugar in DNA is deoxyribose, which has a
 ring in which four of the atoms are carbon and
 the fifth atom is oxygen.

 Deoxyriboseis connected to a phosphate group
 and any one of four nitrogenous bases.
Information Strorage
 The nucleic acid DNA, or deoxyribonucleic
 acid, is the material that contains the
 information.

 The sugar in DNA is deoxyribose, which has
 a ring in which four of the atoms are carbon
 and the fifth atom is oxygen.

 Deoxyriboseis connected to a phosphate
 group and any one of four nitrogenous
 bases.
Information Storage

 Allgenetic information is encoded in
  the sequence of the four bases, which
  are abbreviated to A, G, T, and C.

 Justas history is written in books using
  a 26-letter alphabet, heredity is written
  in DNA using a 4-letter alphabet.
Gene Technology

   Because no one else has the same sequence of
    DNA bases as you, your DNA pattern gives a unique
    “fingerprint” of you.

   A DNA fingerprint is the pattern of bands that
    results when an individual’s DNA sample is
    fragmented, replicated, and separated.

   In DNA fingerprinting, scientists compare
    autoradiographs, which are images that show the
    DNA’s pattern of nitrogenous bases.
Gene Technology

   It takes a lot of DNA to make a DNA fingerprint, so
    scientists must replicate DNA to get a large sample.

   Scientists use polymerase chain reaction, or PCR, to
    replicate a sequence of double-stranded DNA.

   In PCR, scientists add DNA monomers, an enzyme,
    and primers (short lengths of single-stranded DNA
    with a specific sequence) to the sample of DNA.

   Heating and cooling repeatedly replicates the DNA.
Gene Technology

   Each cell of a very young embryo can grow into a
    complete organism. These cells are undifferentiated.

   Undifferentiated cells have not yet specialized to
    become part of a specific body tissue and include
    stem cells in animals and meristem cells in plants.

   When they are cultured artificially they grow into
    complete organisms, clones, that are genetically
    identical to their “parent.”
Gene Technology

   Scientists can insert genes from one species into the
    DNA of another.

   Recombinant DNA is DNA molecules that are
    created by combining DNA from different sources

   When recombinant DNA is placed in a cell, the cell is
    able to make the protein coded by the foreign gene.

   For example, recombinant DNA placed in bacteria
    cells allow the bacteria to make human insulin.
Chapter 20



    Energy and Living
    Systems
Obtaining Energy

   Energy is needed for every action of every organ in
    our bodies. All living things need energy.

   Plants get energy through photosynthesis, the
    process by which they use sunlight, carbon dioxide,
    and water to produce carbohydrates and oxygen.

   Other living things rely on plants for energy.

   The flow of energy throughout an ecosystem relates
    to the carbon cycle, which follows carbon atoms as
    they make up one compound and then another.
Obtaining Energy

   The carbon cycle involves two general reactions:
    photosynthesis and respiration.

   The reactants needed for respiration—glucose and
    oxygen—are produced in photosynthesis.

   The reactants needed for the photosynthesis—
    carbon dioxide, water, and energy—are produced in
    the respiration, although the energy is in a different
    form.
Using Energy

 Glucose   is changed into a more readily
  available source of energy through
  respiration.

 Inbiological chemistry, respiration is the
  process by which cells produce energy from
  carbohydrates.

 In respiration (also called cellular
  respiration), oxygen combines with glucose
  to form water and carbon dioxide.
• For every molecule of glucose that is broken down,
  six molecules of O2 are consumed. Six molecules
  of CO2 and six molecules of H2O are produced.
Using Energy

   While photosynthesis takes in energy, respiration
    gives off energy.

   The thermodynamic values for the equation below
    show that the reaction is very exothermic
    (∆H = −1273 kJ)

   C6H12O6(aq) + 6O2(g) → 6CO2(g) + 6H2O(l)

   Respiration produces chemical energy (not heat
    energy) in the form of special organic molecules.
Using Energy

 Adenosine  triphosphate, ATP, an organic
 molecule that acts as the main energy
 source for cell processes.

 ATPis composed of a nitrogenous base, a
 sugar, and three phosphate groups.

 Adenosine diphosphate, ADP, is the low-
 energy forms of a ATP.
• The main structural difference between ATP and ADP
  is that ATP has an extra phosphate group, −PO3−.
Using Energy

 There
      are three kinds of work fueled by the
 ATP → ADP conversion:

  –   Synthetic work involves making compounds that
      do not form spontaneously.

  –   Mechanical work changes the shape of muscle
      cells, which allows muscles to flex and move.

  –   Transport work involves carrying solutes across
      a membrane.

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CARBOHYDRATES AND LIPIDS

  • 1. Chapter 20 QBA Miguel A. Castro R. Carbohydrates and Lipids
  • 2. Carbohydrates and Living Systems A monosaccharide (C6H12O6) is a simple sugar that is the basic subunit of a carbohydrate. A disaccharide (C12H22O11) is a sugar formed from two monosaccharides. Apolysaccharide is one of the carbohydrates made up of long chains of simple sugars.
  • 3. Carbohydrates and Living Systems  Polysaccharides include starch, glycogen, and cellulose.  Potatoes have a lot of starch, the polysaccharide that plants use for storing energy.  Many animals make use of a similar energy- storage carbohydrate called glycogen.  Cellulose is the polysaccharide that most plants use to give their structures rigidity.
  • 4. To a chemist, sugar is the name given to all monosaccharides and disaccharides.
  • 5. Each molecule of sucrose, the sugar used to sweeten food, is made up of a glucose and a fructose unit.
  • 6. Carbohydrates  Just as two monosaccharides combine to form a disaccharide, many can combine to form a long chain called a polysaccharide.  Polysaccharides may be represented by the general formula below. —O—(C6H10O4)—O—(C6H10O4)—O—(C6H10O4)...
  • 7. Carbohydrates  Polymerization is a series of synthesis reactions that link many monomers together to make a very large, chainlike molecule.  Polysaccharides and other large, chainlike molecules found in living things are called biological polymers.
  • 8.
  • 9.
  • 10. Carbohydrate Reactions  Polysaccharides are changed back to sugars during hydrolysis reactions.  In these reactions, the decomposition of a biological polymer takes place along with the breakdown of a water molecule, as shown in the equation below.
  • 11.
  • 12. Lipids A lipid is a type of biochemical that does not dissolve in water, including fats and steroids.  Lipids generally can have a polar, hydrophilic region at one end of the molecule. For example, oleic acid, shown below is found in the fat of some animals.
  • 13.
  • 14. Lipids  Lipids are used in animals for energy storage as fats.  Cell membranes are made up of lipids called phospholipids.  Steroids, such as cholesterol, are lipids used for chemical signaling.  Waxes, such as those found in candles and beeswax are also lipids.
  • 15.
  • 16. Chapter 20 Proteins
  • 17. Amino Acids and Proteins A protein is a biological polymer that is made up of nitrogen, carbon, hydrogen, oxygen, and sometimes other elements.  Our bodies are mostly made out of proteins.  All proteins are biological polymers made up of amino acid monomers.  An amino acid is any one of 20 different organic molecules that contain a carboxyl and an amino group and that combine to form proteins.
  • 18.
  • 19. Amino Acids and Proteins  Amino refers to the −NH2 group of atoms.  Acid refers to the carboxylic acid group, −COOH.  Thereare 20 natural amino acids. All 20 have the same basic structure.
  • 20. The R represents a side chain.
  • 21.
  • 22. Amino Acids and Proteins  Thereaction by which proteins are made from amino acids is similar to the condensation of carbohydrates.  Thebiological polymer that forms during the condensation of amino acids is called a polypeptide.  The link that joins the N and C atoms of two different amino acids is called a peptide bond.
  • 23.
  • 24.
  • 25.
  • 26. Amino Acids and Proteins  The sequence of amino acids—the primary structure—helps dictate the protein’s final shape. A substitution of just one amino acid in the polypeptide sequence can have major effects on the final shape of the protein. A hereditary blood cell disease called sickle cell anemia gives one example of the importance of amino-acid sequence.
  • 27.
  • 28. Enzymes  Anenzyme is a type of protein that speeds up metabolic reactions in plant and animals without being permanently changed or destroyed.  Almost all of the chemical reactions in living systems take place with the help of enzymes.
  • 29. Enzymes  Enzymes work like a lock and key. That is, only an enzyme of a specific shape can fit the reactants of the reaction that it is catalyzing.  Only a small part of the enzyme’s surface, known as the active site, is believed to make the enzyme active.  In reactions that use an enzyme, the reactant is called a substrate.
  • 30.
  • 31. Chapter 20 Nucleic Acids
  • 32. Information Storage  Allhereditary information is stored chemically in compounds called nucleic acids.  Nucleic acids are an organic compound, either RNA or DNA, whose molecules are made up of one or two chains of nucleotides and carry genetic information.
  • 33. Nucleic-Acid Structure • Like polysaccharides and polypeptides, nucleic acids are biological polymers. They are made up of monomers called nucleotides.
  • 34.
  • 35. Information Storage  The nucleic acid DNA, or deoxyribonucleic acid, is the material that contains the information that determines inherited characteristics.  The sugar in DNA is deoxyribose, which has a ring in which four of the atoms are carbon and the fifth atom is oxygen.  Deoxyriboseis connected to a phosphate group and any one of four nitrogenous bases.
  • 36. Information Strorage  The nucleic acid DNA, or deoxyribonucleic acid, is the material that contains the information.  The sugar in DNA is deoxyribose, which has a ring in which four of the atoms are carbon and the fifth atom is oxygen.  Deoxyriboseis connected to a phosphate group and any one of four nitrogenous bases.
  • 37.
  • 38.
  • 39.
  • 40. Information Storage  Allgenetic information is encoded in the sequence of the four bases, which are abbreviated to A, G, T, and C.  Justas history is written in books using a 26-letter alphabet, heredity is written in DNA using a 4-letter alphabet.
  • 41.
  • 42. Gene Technology  Because no one else has the same sequence of DNA bases as you, your DNA pattern gives a unique “fingerprint” of you.  A DNA fingerprint is the pattern of bands that results when an individual’s DNA sample is fragmented, replicated, and separated.  In DNA fingerprinting, scientists compare autoradiographs, which are images that show the DNA’s pattern of nitrogenous bases.
  • 43.
  • 44. Gene Technology  It takes a lot of DNA to make a DNA fingerprint, so scientists must replicate DNA to get a large sample.  Scientists use polymerase chain reaction, or PCR, to replicate a sequence of double-stranded DNA.  In PCR, scientists add DNA monomers, an enzyme, and primers (short lengths of single-stranded DNA with a specific sequence) to the sample of DNA.  Heating and cooling repeatedly replicates the DNA.
  • 45.
  • 46. Gene Technology  Each cell of a very young embryo can grow into a complete organism. These cells are undifferentiated.  Undifferentiated cells have not yet specialized to become part of a specific body tissue and include stem cells in animals and meristem cells in plants.  When they are cultured artificially they grow into complete organisms, clones, that are genetically identical to their “parent.”
  • 47.
  • 48. Gene Technology  Scientists can insert genes from one species into the DNA of another.  Recombinant DNA is DNA molecules that are created by combining DNA from different sources  When recombinant DNA is placed in a cell, the cell is able to make the protein coded by the foreign gene.  For example, recombinant DNA placed in bacteria cells allow the bacteria to make human insulin.
  • 49. Chapter 20 Energy and Living Systems
  • 50. Obtaining Energy  Energy is needed for every action of every organ in our bodies. All living things need energy.  Plants get energy through photosynthesis, the process by which they use sunlight, carbon dioxide, and water to produce carbohydrates and oxygen.  Other living things rely on plants for energy.  The flow of energy throughout an ecosystem relates to the carbon cycle, which follows carbon atoms as they make up one compound and then another.
  • 51.
  • 52.
  • 53. Obtaining Energy  The carbon cycle involves two general reactions: photosynthesis and respiration.  The reactants needed for respiration—glucose and oxygen—are produced in photosynthesis.  The reactants needed for the photosynthesis— carbon dioxide, water, and energy—are produced in the respiration, although the energy is in a different form.
  • 54.
  • 55. Using Energy  Glucose is changed into a more readily available source of energy through respiration.  Inbiological chemistry, respiration is the process by which cells produce energy from carbohydrates.  In respiration (also called cellular respiration), oxygen combines with glucose to form water and carbon dioxide.
  • 56. • For every molecule of glucose that is broken down, six molecules of O2 are consumed. Six molecules of CO2 and six molecules of H2O are produced.
  • 57. Using Energy  While photosynthesis takes in energy, respiration gives off energy.  The thermodynamic values for the equation below show that the reaction is very exothermic (∆H = −1273 kJ)  C6H12O6(aq) + 6O2(g) → 6CO2(g) + 6H2O(l)  Respiration produces chemical energy (not heat energy) in the form of special organic molecules.
  • 58. Using Energy  Adenosine triphosphate, ATP, an organic molecule that acts as the main energy source for cell processes.  ATPis composed of a nitrogenous base, a sugar, and three phosphate groups.  Adenosine diphosphate, ADP, is the low- energy forms of a ATP.
  • 59. • The main structural difference between ATP and ADP is that ATP has an extra phosphate group, −PO3−.
  • 60.
  • 61. Using Energy  There are three kinds of work fueled by the ATP → ADP conversion: – Synthetic work involves making compounds that do not form spontaneously. – Mechanical work changes the shape of muscle cells, which allows muscles to flex and move. – Transport work involves carrying solutes across a membrane.