The pituitary gland secretes nine hormones that regulate many body functions and control other endocrine glands. The hypothalamus controls pituitary secretions. Key glands include the thyroid, which regulates metabolism, and the parathyroid glands, which maintain calcium homeostasis in blood with thyroid hormones. The pancreas regulates blood glucose levels via insulin and glucagon. The ovaries and testes produce gametes and sex hormones.