MCQ questions on basic and diagnostic microbiology for UG -Medical/ Nursing/ Paramedical students.

1. MCQs for UG Students
Dr. Suprakash Das
M.D (Microbiology)

2. Basic Theory MCQs
1. Which one of the following is an obligate intracellular
organism
a. Salmonella typhi
b. Shigella flexneri
c. Mycobacterium tuberculosis
d. Chlamydia psittaci
2. Which of the following organism causes LGV
a. C. pneumoniae
b. C. trachomatis
c. C. psittaci
d. Mycoplasma spp.
3. Which one of the following is metabolically active
a. Elementary body
b. Reticulate body
c. Negri bodies
d. None of them

3. Basic Theory MCQs
4. Which of the serotype of Chlamydia is associated with “Trachoma”
a. Serotype A
b. Serotype L1
c. Serotype D
d. Serotype K
5. Which of the following organism is most commonly responsible for NGU
a. E. coli
b. Mycoplasma spp
c. Ureaplasma urealyticum
d. C. trachomatis
6. Which of the following organism causes Hypersensitive pneumonitis
a. C. trachomatis
b. C. psittaci
c. C. pneumoniae
d. S. pneumoniae

4. Diagnosis- MCQs
7. Which of the following sample is used to diagnose urogenital
Chlamydial infections
a. Swab
b. Tissue biopsy
c. Urine
d. Stool
8. Which of the following culture media is best for Chlamydial isolation
a. Chocolate agar
b. MacConkey agar
c. Monkey kideney cell line
d. HeLa cells
9. Which of the following diagnostic techniques isn’t used for Chlamydial
infections
a. DFA
b. Shell vial culture
c. Agglutination
d. PCR

5. Basic Theory MCQs
10. Which of the following birds is associated with Cryptococcosis.
a. Parrot
b. Crow
c. Peacock
d. Pigeon
11. Which of the following clinical conditions isn’t associated with
Cryptococcosis.
a. HIV infection
b. Organ transplantation
c. Treatment with corticosteroids
d. Tuberculosis
12. Which of the following isn’t a virulence factor for C. neoformans
a. Capsule
b. Melanin Production
c. Growth at 370C
d. Toxin production

6. Basic Theory MCQs
13. Which of the following organ isn’t effected by C. neoformans.
a. Meninges
b. Lung
c. Skin
d. Kidney
14. Which of the following isn’t a clinical feature of Cryptococcal meningitis
a. Headache
b. Confusion
c. Hypothermia
d. Nausea & Vomiting
15. Which of the following isn’t a clinical feature of Cryptococcal pulmonary
infection
a. Cough
b. Low grade fever
c. Pleuritic pain
d. Consolidation

7. Diagnosis- MCQs
16. Which of the following stain isn’t used for diagnosis of
Cryptococcus.
a. India Ink
b. Nigrosin stain
c. Aclain blue
d. Geimsa stain
17. Which of the following culture media isn’t used to look for
Melanin production
a. Bird seed agar
b. Niger seed agar
c. Caffaic seed agar
d. Mueller Hinton agar
18. Which of the following isn’t true for C. neoformans
a. Urease test +ve
b. Assimilation of Inositol
c. Assimilation of maltose
d. Utilizes Citrate

8. Diagnosis- MCQs
19. Which test has the highest sensitivity to detect Cryptococcal meningitis
a. India ink mount
b. Culture on SDA
c. Ag- detection by ICT
d. Gram stain
20. WBC count(>1500 cells/mm3) in CSF of a meningitis patient is most
likely due
a. Bacterial infection
b. Viral
c. Fungal
d. Tubercular
21. L-A Test can be used to detect bacterial pathogen causing meningitis
for all except
a. S. pneumoniae
b. H. influenzae
c. N. meningitidis
d. S. epidermidis

9. Basic Theory MCQs
22. Which of the following isn’t a causative agent for viral
meningitis
a. Human Enteroviruses
b. HSV
c. WNV
d. Adenoviruses
23. All are signs of Meningeal irritation except
a. Neck rigidity
b. Brudzinski’s sign
c. Kernig’s sign
d. Pappilodema
24. Chronic meningitis is caused by all except
a. M. tuberculosis
b. T. pallidum
c. Nocardia spp.
d. MRSA

10. Treatment- MCQs (Match the table)
Sr. No. Organism/ Clinical condition Antimicrobial
1 N. meningitidis Doxycyclin 100 mg BD
2 P. aeruginosa Cefotaxim
3 HSV Flucitosin
4 Cryptococcal meningitis Ceftazidime
5 MRSA Azithromycin-(1-g single oral
dose)
6 Listeria monocytogens Ceftriaxone
7 Inclusion conjunctivitis Liposomal Amphitericin B
8 H. influenzae Meropenem
9 S. agalactiae Vancomycin
10 Fusobacterium spp Ampicillin + Gentamicin
11 C. trachomatis L1 Ampicillin
12 WNV Metronidazole

11. MCQ-Answers
1. -D 13. -D
2. -B 14. -C
3. -B 15. -D
4. A 16. -D
5. -D 17. -D
6. -B 18. - D
7. -D 19. -C
8. -D 20. – A
9. -C 21. -D
10. -A 22. -D
11. -D 23. -D
12. -D 24. -D

12. Table Match
Organism/ Clinical condition Sr. No. Antimicrobial Sr. No.
1 6
2 4/8
3 None
4 7+3
5 9
6 10
7 5
8 11/2
9 11
10 12
11 1
12 None