2. ABORTION
⢠Abortion is the expulsion or
extraction from its mother of
an embryo or fetus weighing
500gm or less, when it is not
capable of independent survival.
6. ⢠Anatomical abnormalities:
ďź Cervical incompetence-congenital or acquired
ďź Congenital malformation of the uterus: bicornuate or septate
uterus
⢠Infections:
ďź Viral:rubella,cmv,variola,hiv
ďź Parasitic:toxoplasma,malaria
ďź Bacteria:ureaplasma,chlamydia,brucella
⢠Immunological:5-10%
⢠Autoimmune and alloimmune disorders: Antigen & antibody
reactions
7. ď§ Blood group incompatibility: couple with
group A and group o, have got higher incidence of
abortion.
ď§ PROM: inevitably leads to
ď§ abortion
ď§ Environmental factors:
ďźCigarette smoking
ďźAlcohol consumption
ďźContraceptive agents
ďźDrugs ,chemical agents
⢠Others :increased uterine irritability, fibroids of
uterus, intrauterine adhesions.
8. THREATENED ABORTION
⢠It is clinical entity where the process of
abortion has started but has not progressed to
a state from which recovery is
impossible.............
⢠Clinical features:
ďź Bleeding per vaginum-slight bright red in color
ďź Pain
9.
10. Investigations:
ď§ BLOOD-For Hb,hematocrit,ABO,Rh typing
ď§ Urine- HCG
ď§ USG-for fetal movements
Treatment:
ďź Rest
ďź Drugs: sedation for relief of pain
ďź General measures: preservation of vulval pads
ďź To report if bleeding aggravated
Prognosis:
12. 02.INEVITABLE ABORTION:
⢠It is clinical type of abortion where the
changes have progressed to a state from
where the recovery is impossible.....
⢠Clinical features:
ďźIncreased vaginal bleeding
ďźAggravation of pain on lower abdomen
ďźGeneral condition is proportion to blood loss
ďźDilated internal os of the cervix
13. Management
⢠General measures:
ďźExcessive bleeding should be controlled by
methargin
ďźShock should be corrected
ďźDilatation & evacuation before 12 weeks
ďźOxytocin infusion after 12 weeks
14. Complete abortion
When the products of conception are
expelled in mass,it is called complete
abortion.
Clinical features:
ďźExpulsion of fleshy mass per vaginum
ďźVaginal bleeding become trace or
absent
15. ⢠Internal examination:
ďźUterus is smaller than the period of
amenorrhoea
ďźCervical os closed
ď§ Management :
ďźAssess & treat effect of blood loss
ďźUterine curretage
ďźRh immunization
16. Incomplete abortion
⢠When the entire products of conceptions are not
expelled,instead a part of it is left remain inside
the cavity,is called incomplete abortion
⢠Clinical features:
ďźPain in lower abdomen
ďźPersistence of vaginal bleeding
ďźInternal examination reveals: uterus is smaller
than the period of amenorrhoea
ďźOs opened
ďźbleeding
17. Termination: products left behind may lead to
ďźProfuse bleeding
ďźSepsis
ďźPlacental polyp
Management:
ďźDilatation and evacuation under GA
ďź Treat Shock
ďźOxytocin infusion
18. Missed abortion
⢠When the fetus is dead and retained
inside the uterus for variable period, it
is called missed abortion or silent
miscarriage or early fetal demise.
19. Clinical features
⢠Persistence of brownish vaginal discharge
⢠Subsidence of pregnancy symptoms
⢠Retrogression of breast changes
⢠Cessation of uterine growth
⢠Non audibility of FHS
⢠Cx feels firm
⢠HCG negative
⢠USG reveals empty sac
20. Management
⢠Uterus is less than 12 weeks:
ďśVaginal evacuation:D+E under GA
⢠Uterus is more than 12 weeks:
ďśOxytocin -10-20 units with 30 drops per minute
ďśProstaglandins:more effective than oxytocin in
such cases,
ďźMisoprostol 200macrogram tab for 4 hourly
ďźCarboprost tromethamine 250 macro gm 3
hourly.
21. Septic abortion
⢠Any abortion associated with clinical
evidences of infection of the uterus and its
contents is called septic abortion
ďźRise of temperature of 100.4 degree F
ďźOffensive discharge
ďźLower abdominal pain and tenderness
22. ⢠Incidence :10% are septic abortions in hospital
admissions
⢠Clinical features:
ďźPyrexia
ďźPain in abdomen
ďźTachycardia 100-120/min
ďźInternal examination reveals that, offensive
vaginal discharge
Clinical grading:
Grade 1:infection is localised to uterus
Grade 2: beyond the uterus
Grade 3: generalised peritonitis
23. ⢠Investigations:
ďCulture &sensitivity test
ďBlood for investigations
ďUrine analysis
ďUSG
⢠Complications:
ďźImmediate :haemorrhage,injury
ďźSpread of infection leads to:generalized
peritonitis,endotoxic shock,ARF,
Thrombophlebitis.
25. MANAGEMENT
⢠GENERAL MANAGEMENT:
ďźHospitalization
ďźCulture &sensitivity
ďźVaginal examination
ďźInvestigation protocol
⢠GRADE 1:
o Antibiotics
o Prophylactic antiserum gas gangrene
o Analgesics and sedatives
o Evacuation of the uterus following 24 hr
of antibiotic therapy
26. ⢠Grade 2:
ďźAntibiotic therapy:for gram positive aerobes
aq.penicillin G 5 millon units for 6 hours,ampicillin
0.5-1gm IV every 6 hours
ďźFor gram negative aerobes:gentamycin 1.5 mg
ceftrixone 1 gm
ďźFor anerobes:metrogyl 500mg,clindamycin 600mg
ďźSurgery:posterior colpotomy
⢠Grade 3:
⢠antibiotics,intensive care management
ďźLaprotomy for hysterectomy
27. Recurrent miscarriage
⢠Sequence of 3 or more consecutive spontaneous
abortion before 20th weeks is called habitual or
recurrent abortion
⢠1%of women in reproductive age group
Etiology:
First trimister abortion:
ďźGenetic factors
ďźEndocrine and metabolic
ďźInfection
ďźInherited thrombophilia
ďźImmunological causes
28. ⢠Second trimister:
ďźAnatomic abnormalities
ďźCervical incompetence
⢠Investigations:
ďźBlood
ďźAutoimmune screening
ďźSerum LH
ďźUSG
ďźCulture and sensitivity
30. ⢠DURING PREGNANCY:
ďźReassurance and TLC
ďźPrenatal diagnosis
ďźUSG
⢠Hormonal treatment for LPD
⢠Treat medical disorders during
pregnancy
⢠Surgical management:
ďźShirodkarâs operation
ďźMc Donaldâs operation
31. Shirodkarâs operation
⢠Pt is put under light GA
⢠Lithotomy position
⢠Place the vaginal speculum for exposure of Cx
⢠Transverse incision on the below the base of the
bladder and bladder is pushed up to expose the
level of internal os,
⢠Vertical incision on the posterior cervix
⢠The non absorbable material is passed posteriorly
with the help of cervical needle
⢠The ends of suture are tied up by reef knot
32.
33. Mc Donaldâs operation
⢠Also called as cervical stitching
⢠Bed rest for 2-3 days
⢠Tocolytics
⢠Antenatal advice
⢠Avoid intercourse
⢠To avoid journey
⢠Periodic monitoring by USG
⢠removal of stitch by 38th week prior to
labor
37. Medical termination of pregnancy
ďźMTP act has been enforced in the year of April
1972
ďźProvisions of the act have been revised in
1975
38. Indications
⢠To Save the life of the mother:
ďźCardiac diseases grade 3 and 4
ďźChronic glomerulonephritis
ďźMalignant hypertension
ďźIntractable hyperemesis gravidarum
ďź cervical or breast malignancy
ďźDiabetes with retinopathy
ďźEpilepsy
ďźPsychiatric illness
39. ⢠Social indications:
ď§ To prevent injury to Physical and mental
health of the mother
ď§ rape or Unplanned pregnancy
ď§ Low socio economic status
⢠Eugenic indications: risk of child being born
with physical and mental abnormalities.
ďźAnencephaly
ďźDownâs syndrome
ďźHaemophilia
ďźTeratogenic drugs affected
40. Recommendations
⢠One has assisted at least 25 MTP in an authorised
centre and having certificate
⢠One has got 6 months of house surgeon training in
OBG
⢠One has got diploma or degree in OBG
⢠Termination can only performed in hospitals,
established or maintained by the government or places
approved by the government.
⢠Termination is permitted up to 20 weeks
41. ⢠Pregnancy can only terminated on the written
consent of the women, husbandâs consent is not
required.
⢠Pregnancy in minor girl or lunatic cannot be
terminated without written consent of the
parents or legal guardians.
⢠The abortion has to be performed confidentially
and to be reported to director of health services
of state in prescribed form.
42. First trimister termination methods
⢠Manual vaccum aspiration:
ďIt is done up to 7 menstrual weeks with
minimal cervical dilatation
ďWith flexible vaccum cannula(6mm)and 50ml
plastic syringe
Advantages:
ďźIt is quicker
ďźLess traumatic
ďźsafer
43.
44. Dilatation &curretage
⢠This is procedure is done in first trimister
⢠The cervix is dilated with small metal dialtors
and suction cannula is introduced in to the
uterine cavity
⢠With cannula fitted to a suction machine ,the
products of conception are sucked out
⢠With the small flushing currette,the uterine
cavity is curetted and suctioned out once again
for any remaining portion of the conceptus
⢠Prophylactic dose of methergine
45. Dilatation and evacuation
⢠This is done either as two stage procedure(slow)
or one stage(rapid) method
⢠For two stage
ďźAchieve the cervical dilation with the help of
laminaria tents, the woman is kept in bed for 12
hours during which time it swell up, after 12
hours the tents are removed and further
dilatated with metal dilators
ďźThe products of conception is removed with
ovum forceps.
ďźMethergine adminstration
46. ⢠One stage:
ďźCervical dilation with metal dilators followed by
evacuation is done with one stage.
⢠Pharmacological methods:
ďźMifepristone: a single dose of 600mg oraly for
abortion ,if it fails prostglandin E1 vaginal
pessary to complete abortion process.
ďźMethotrexate:
ďźIntramuscularly
ďźProducts of conception expells after 3 to 4
hours.
47. Second trimister termination
⢠Intrauterine instillation
⢠Extra uterine instillation
⢠Prostaglandins
⢠oxytocin
⢠Hysterotomy
48. Intra amniotic instillation
⢠Hyper-tonic saline is instilled through a
polythene tube connected to a drip set in to
amniotic cavity
⢠An amount of 10 ml multiplied by number of
weeks of gestation is infused at a rate of 10ml
per minute.
⢠Expulsion of products takes place
49. Extra uterine instillation
⢠This is done by instillation of ethacrydine
lactate 0.1% solution vaginally above the
internal os.
⢠Presence of the solution between the
membranes and myometrium results in
stripping of the membrane and cx dilatation
takes place.
⢠Expulsion of the products of conception
follows.