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Introduction to Virology Brief History, Viral Structure and Classification, and Role of Host Cells in Viral Infections
Smallpox (Variola Virus) – 10th Century B.C. ,[object Object],[object Object],[object Object]
Smallpox (Variola Virus) -10th Century B.C. ,[object Object],[object Object],[object Object]
Smallpox – 18th Century ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Smallpox – 20th Century ,[object Object],[object Object]
Smallpox – 20 th   Century ,[object Object],[object Object],[object Object]
Smallpox – 21 st  Century ,[object Object]
Smallpox – 21 st   Century ,[object Object]
Tobacco Mosaic Virus (TMV) ,[object Object],[object Object]
TMV ,[object Object]
Bacterial Viruses ,[object Object]
Bacterial Viruses ,[object Object],[object Object],[object Object],[object Object],[object Object]
RNA Tumor Viruses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
RNA Tumor Viruses ,[object Object]
DNA Tumor Viruses ,[object Object]
DNA Tumor Viruses ,[object Object],[object Object],Human Papilloma  Virus
Emerging Infections
Emerging Viruses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Emerging Viruses ,[object Object],[object Object],[object Object]
Emerging Viruses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Emerging Viruses ,[object Object],[object Object]
Introduction to Virology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Variation in virus size
What is a virus? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Types of viral nucleic acid
What is a virus? ,[object Object],[object Object],[object Object],[object Object]
Growth curves of bacteria (A) versus bacteriophages (B)
Differences in growth curves: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The multiplication cycle of a virus
One step growth curve ,[object Object]
What is a virion? ,[object Object]
Structure of viruses: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Capsomers, continued ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Helical Structure
Helical structure
Capsid architecture continued ,[object Object],[object Object],[object Object],[object Object]
Icosahedral architecture
Icosahedral architecture
Capsid architecture continued ,[object Object]
Poxvirus
Reovirus
Structure of Viruses, continued ,[object Object],[object Object],[object Object]
Enveloped viruses Sindbis virus: an enveloped icosahedron
Enveloped viruses Influenza A virus (an orthomyxovirus) and vesicular stomatitis virus (a rhabdovirus): viruses with enveloped helical structures. Although their morphology is different, these viruses are constructedin the same way.
Structure of Viruses, continued ,[object Object],[object Object],[object Object]
Budding
Enveloped viruses ,[object Object],[object Object],[object Object]
Enveloped viruses ,[object Object],[object Object],[object Object],[object Object],[object Object]
Types of viral proteins associated with the envelope Influenza   virus
Structural Roles of Host Cells in Viral Infections ,[object Object],[object Object],[object Object],[object Object]
Receptors on animal cells
Structural Roles of Host Cells in Viral Infections ,[object Object],[object Object],[object Object],[object Object]
Eukaryotic cells ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Eukaryotic cells, continued ,[object Object],[object Object],[object Object],[object Object]
Classification of Viruses ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The Baltimore Classification of Viruses ,[object Object],[object Object],[object Object],[object Object],[object Object]
Baltimore Classification of Viruses

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33. introduction to virology