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VOIDING DISORDERS
 Presented By:
 Sukhpreet Kaur
PPT-3
Function of Lower Urinary
Tract
 STORAGE of adequate volumes of urine at low
pressure & with no leakage
 EMPTYING that is
 Voluntary
 Efficient
 Complete
 Low pressure
5/8/2020 2
Anatomy of the Lower Urinary
Tract
 Bladder (detrusor)
 Stores urine at low pressure
 Compresses urine for voiding
 Urethra
 Conveys urine from bladder to outside world
 Sphincter(s) internal & external
 Controls urine flow & maintain continence
between voidings
5/8/2020
ADULT VOINDING DYSFUNCTION
1.URINARY INCONTINENCE:-
 Urinary incontinence means
involuntary urination or leakage
of urine.
5/8/2020 4
EPIDEMIOLOGY
 More than 17 million adults in the
united states are estimated to have
urinary incontinence.
5/8/2020 5
RISK FACTORS
 Pelvic muscle weakness
 Age- related changes
 Urinary disorders
 High-impact exercise
 stress
5/8/2020 6
TYPES
 STRESS INCONTINENCE
 URGE INCONTINENCE
 REFLEX INCONTINENCE
 OVERFLOW INCONTINENCE
5/8/2020 7
MANAGEMENT
 Behavioral therapy
 Pharmacologic therapy
5/8/2020 8
2.URINARY RETENTION
 Urinary retention is inability to empty the
bladder completely during attempts to
void.
CAUSES:-
Prostatic enlargement
Pregnancy
Infection
Neurologic disorders
5/8/2020 9
3.NEUROGENIC BLADDER
 Neurologic bladder is a dysfunction that
results from a lesion of the nervous
system.
 CAUSES
 Spinal injury
 Multiple sclerosis
5/8/2020 10
5/8/2020 11
Benign Prostatic Hyperplasia
 Generalised disease of the
prostate due to hormonal
derangement which leads
to enlargement of the
gland .
INCIDENCES
 Occurs in 50% of men over 50 and in 80% of
men over 80 have BPH.
 Many men with BPH may have mild
symptoms and may never need treatment.
 In India total no patients 1,696,347.
5/8/2020 12
BPH Etiologies
 Cause not completely understood
 Change in hormonal with alterations in the
testosterone/estrogen balance
 Induction of prostatic growth factors
 Increased stem cells
 Accumulation of dihydroxytestosterone.
5/8/2020 14
Benign Prostatic Hyperplasia
BPH Pathophysiology
Normal BPH
Hypertrophied
detrusor muscle
Obstructed
urinary flow
PROSTATE
BLADDER
URETHRA
Kirby RS et al. Benign prostatic hyperplasia. Health Press, 1995.
BPH
Pathophysiology
 Slow and insidious changes over time
 Complex interactions between prostatic urethral
resistance, intravesical pressure, detrussor
functionality, neurologic integrity, and general
physical health.
 Initial hypertrophydetrussor decompensation
poor tonediverticula formationincreasing urine
volumehydronephrosisupper tract dysfunction
5/8/2020 17
Clinical manifestations
 Voiding symptoms
 decrease in the urinary stream
 Dribbling at the end of urination
 Hesitancy
 Pain or burning during urination
 Feeling of incomplete bladder emptying
5/8/2020 18
Clinical manifestations
 Irritative symptoms
urinary frequency
dysuria
bladder pain
nocturia
incontinence
symptoms associated with infection
5/8/2020 19
Diagnostic Tests
 History & Examination
 Digital rectal exam (DRE)
 Urinalysis
 Urine culture
 BUN
 Prostate specific
antigen (PSA)
 Transrectal
ultrasound – biopsy
 Uroflometry
5/8/2020 20
DRE
MANAGEMENT OF BPH
5/8/2020 22
MANAGEMENT OF BPH
 Catheterization (stylet)
 Watchful waiting and behavioral modification
 Medical Management
 Alpha blockers
 5-alpha reductase inhibitors
 Combination therapy
 Surgical Management
 Urethral stents
Watchful Waiting and Behavioral
Modification
 “is the preferred management technique in
patients with mild symptoms.
 AUA score < 7,
Watchful Waiting and Behavioral
Modification
 Decrease caffeine, alcohol )diuretic effect(
 Avoid taking large amounts of fluid over a short
period of time
 Void whenever the urge is present, every 2-3 hours
 Maintain normal fluid intake, do not restrict fluid
 Avoid bladder irritants to include dairy products,
artificial sweeteners, carbonated beverages
 Limit nighttime fluid consumption
 BPH symptoms can be variable, intermittent
5/8/2020 26
Medical Management
Alpha adrenergic receptor blockers
 promote smooth muscle relaxation in the prostate
 Relaxation of the muscles facilitates urinary flow
 Doxazosin (Cardura), Terazosin (Hytrin),
Tamsulosin (Flomax), Alfuzosin (Uroxatral)
5/8/2020 27
Medical Management
5 alpha reductase inhibitor )finasteride :
Proscar(
 Reduce size of prostate gland by up to 30 %
 Blocks the enzyme of 5 alpha reductase
which is necessary to stop the conversion of
testosterone to dihydroxytestostersone
Combination Therapy
 Concomitant use of alpha blockers and
5-alpha reductase inhibitors
 Should be reserved for patients who
are at significant risk of progression
and adverse outcome
 Poor surgical candidate
 Patient wants to avoid surgery
 Significant cost associated with dual
medications
5/8/2020 29
Medical Management
 Herbal therapy –
saw palmetto fruit –
use to improve
urinary symptoms
and urinary flow
 Problem with herbal
therapy – long term
effectiveness
surgical treatment
Surgical Management
 Minimally Invasive techniques
 1. Transurethral Microwave thermotherapy
 2.Transurethral needle ablation.
Surgical Management
 Open simple prostatectomy
 TURP (Transurethral Prostatectomy)
 Transurethral incision of the prostate
 Laser Prostatectomy
TURP
“Gold Standard” of care for BPH
NURSING MANAGEMENT
5/8/2020 34
5/8/2020 35
Preoperative care
 Antibiotics
 Allow pt to discuss concerns about
surgery on sexual functioning
 Prostatic surgery may result in
retrograde ejaculation
5/8/2020 36
Postoperative Goals
 No complications
 Restoration of urinary control
 Complete bladder emptying
5/8/2020 37
Postoperative Care
 Monitoring
 Continuous irrigation & maintain catheter
patency
 Blood clots and hematuria are expected for
the first 24-36 hours
 After catheter is removed – check for urinary
retention and urinary stream
5/8/2020 38
Discharge planning
 Catheter care
 Managing urinary incontinence
 Oral fluid intake – 2,000-3,000 cc per day
 Observe for s/s of urinary tract infection
 Prevent constipation
 Avoid lifting
 No driving or intercourse after surgery
BPH TREATMENT
New Modalities
 Minimally invasive: (Prostatic
Stents,TUNA,TUMT, HIFU,Water-
induced Thermotherapy)
 Laser prostatectomy
(VLAP,ILC,CLAP,TULIP,HoLRP)
 Electrovaporization (TUVP,TVRP)
summary
5/8/2020 40

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Benign prostatic hyperplasia

  • 1. VOIDING DISORDERS  Presented By:  Sukhpreet Kaur PPT-3
  • 2. Function of Lower Urinary Tract  STORAGE of adequate volumes of urine at low pressure & with no leakage  EMPTYING that is  Voluntary  Efficient  Complete  Low pressure 5/8/2020 2
  • 3. Anatomy of the Lower Urinary Tract  Bladder (detrusor)  Stores urine at low pressure  Compresses urine for voiding  Urethra  Conveys urine from bladder to outside world  Sphincter(s) internal & external  Controls urine flow & maintain continence between voidings 5/8/2020
  • 4. ADULT VOINDING DYSFUNCTION 1.URINARY INCONTINENCE:-  Urinary incontinence means involuntary urination or leakage of urine. 5/8/2020 4
  • 5. EPIDEMIOLOGY  More than 17 million adults in the united states are estimated to have urinary incontinence. 5/8/2020 5
  • 6. RISK FACTORS  Pelvic muscle weakness  Age- related changes  Urinary disorders  High-impact exercise  stress 5/8/2020 6
  • 7. TYPES  STRESS INCONTINENCE  URGE INCONTINENCE  REFLEX INCONTINENCE  OVERFLOW INCONTINENCE 5/8/2020 7
  • 8. MANAGEMENT  Behavioral therapy  Pharmacologic therapy 5/8/2020 8
  • 9. 2.URINARY RETENTION  Urinary retention is inability to empty the bladder completely during attempts to void. CAUSES:- Prostatic enlargement Pregnancy Infection Neurologic disorders 5/8/2020 9
  • 10. 3.NEUROGENIC BLADDER  Neurologic bladder is a dysfunction that results from a lesion of the nervous system.  CAUSES  Spinal injury  Multiple sclerosis 5/8/2020 10
  • 11. 5/8/2020 11 Benign Prostatic Hyperplasia  Generalised disease of the prostate due to hormonal derangement which leads to enlargement of the gland .
  • 12. INCIDENCES  Occurs in 50% of men over 50 and in 80% of men over 80 have BPH.  Many men with BPH may have mild symptoms and may never need treatment.  In India total no patients 1,696,347. 5/8/2020 12
  • 13. BPH Etiologies  Cause not completely understood  Change in hormonal with alterations in the testosterone/estrogen balance  Induction of prostatic growth factors  Increased stem cells  Accumulation of dihydroxytestosterone.
  • 15. BPH Pathophysiology Normal BPH Hypertrophied detrusor muscle Obstructed urinary flow PROSTATE BLADDER URETHRA Kirby RS et al. Benign prostatic hyperplasia. Health Press, 1995.
  • 16. BPH Pathophysiology  Slow and insidious changes over time  Complex interactions between prostatic urethral resistance, intravesical pressure, detrussor functionality, neurologic integrity, and general physical health.  Initial hypertrophydetrussor decompensation poor tonediverticula formationincreasing urine volumehydronephrosisupper tract dysfunction
  • 17. 5/8/2020 17 Clinical manifestations  Voiding symptoms  decrease in the urinary stream  Dribbling at the end of urination  Hesitancy  Pain or burning during urination  Feeling of incomplete bladder emptying
  • 18. 5/8/2020 18 Clinical manifestations  Irritative symptoms urinary frequency dysuria bladder pain nocturia incontinence symptoms associated with infection
  • 19. 5/8/2020 19 Diagnostic Tests  History & Examination  Digital rectal exam (DRE)  Urinalysis  Urine culture  BUN  Prostate specific antigen (PSA)  Transrectal ultrasound – biopsy  Uroflometry
  • 21.
  • 23. MANAGEMENT OF BPH  Catheterization (stylet)  Watchful waiting and behavioral modification  Medical Management  Alpha blockers  5-alpha reductase inhibitors  Combination therapy  Surgical Management  Urethral stents
  • 24. Watchful Waiting and Behavioral Modification  “is the preferred management technique in patients with mild symptoms.  AUA score < 7,
  • 25. Watchful Waiting and Behavioral Modification  Decrease caffeine, alcohol )diuretic effect(  Avoid taking large amounts of fluid over a short period of time  Void whenever the urge is present, every 2-3 hours  Maintain normal fluid intake, do not restrict fluid  Avoid bladder irritants to include dairy products, artificial sweeteners, carbonated beverages  Limit nighttime fluid consumption  BPH symptoms can be variable, intermittent
  • 26. 5/8/2020 26 Medical Management Alpha adrenergic receptor blockers  promote smooth muscle relaxation in the prostate  Relaxation of the muscles facilitates urinary flow  Doxazosin (Cardura), Terazosin (Hytrin), Tamsulosin (Flomax), Alfuzosin (Uroxatral)
  • 27. 5/8/2020 27 Medical Management 5 alpha reductase inhibitor )finasteride : Proscar(  Reduce size of prostate gland by up to 30 %  Blocks the enzyme of 5 alpha reductase which is necessary to stop the conversion of testosterone to dihydroxytestostersone
  • 28. Combination Therapy  Concomitant use of alpha blockers and 5-alpha reductase inhibitors  Should be reserved for patients who are at significant risk of progression and adverse outcome  Poor surgical candidate  Patient wants to avoid surgery  Significant cost associated with dual medications
  • 29. 5/8/2020 29 Medical Management  Herbal therapy – saw palmetto fruit – use to improve urinary symptoms and urinary flow  Problem with herbal therapy – long term effectiveness
  • 31. Surgical Management  Minimally Invasive techniques  1. Transurethral Microwave thermotherapy  2.Transurethral needle ablation.
  • 32. Surgical Management  Open simple prostatectomy  TURP (Transurethral Prostatectomy)  Transurethral incision of the prostate  Laser Prostatectomy
  • 33. TURP “Gold Standard” of care for BPH
  • 35. 5/8/2020 35 Preoperative care  Antibiotics  Allow pt to discuss concerns about surgery on sexual functioning  Prostatic surgery may result in retrograde ejaculation
  • 36. 5/8/2020 36 Postoperative Goals  No complications  Restoration of urinary control  Complete bladder emptying
  • 37. 5/8/2020 37 Postoperative Care  Monitoring  Continuous irrigation & maintain catheter patency  Blood clots and hematuria are expected for the first 24-36 hours  After catheter is removed – check for urinary retention and urinary stream
  • 38. 5/8/2020 38 Discharge planning  Catheter care  Managing urinary incontinence  Oral fluid intake – 2,000-3,000 cc per day  Observe for s/s of urinary tract infection  Prevent constipation  Avoid lifting  No driving or intercourse after surgery
  • 39. BPH TREATMENT New Modalities  Minimally invasive: (Prostatic Stents,TUNA,TUMT, HIFU,Water- induced Thermotherapy)  Laser prostatectomy (VLAP,ILC,CLAP,TULIP,HoLRP)  Electrovaporization (TUVP,TVRP)