Epigenetics presentation

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Student Wilsonsbiologylab

Epigenetics By Abby Johnson, Angel Vaughn, and Daniele Marcato

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What is an Epigenome? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Fetal alcohol spectrum disorders (FASDs) are characterized by life-long changes in gene expression, neurodevelopment and behavior. What mechanisms initiate and maintain these changes are not known, but current research suggests a role for alcohol-induced epigenetic changes. We assessed alterations to adult mouse brain tissue by assaying DNA cytosine methylation and small noncoding RNA (ncRNA) expression, specifically the microRNA (miRNA) and small nucleolar RNA (snoRNA) subtypes. We found long-lasting alterations in DNA methylation as a result of fetal alcohol exposure, specifically in the imprinted regions of the genome harboring ncRNAs and sequences interacting with regulatory proteins. The findings of this study help to expand on the mechanisms behind the long-lasting changes in the brain transcriptome of FASD individuals. Webinar Link: http://www.youtube.com/watch?v=fzdc0GIdCnA

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Is there an ideal way for parents and health carers to ensure babies get the best start in life? All agree that every precious baby deserves the best possible start in life. But what is the best possible start and when does that start begin – before or after birth? With all that we already know and understand about pregnancy and infant development, do we truly understand the obstacles and opportunities at the heart of raising a child to its full potential? This public lecture traces the journey of a child from the moments before conception to its first years as an infant. It considers the complex influences at work on mother and child such as fear, anxiety, social expectations and intergenerational parenting experiences. Insights will be offered based on cutting-edge research from which all would-be parents, infant care professionals and wider community would benefit. Professor Maralyn Foureur Maralyn is Professor of Midwifery at UTS and for the Central Coast and Northern Sydney Local Health Networks. She has led research in innovative models of midwifery care and the development of midwifery practice and education. Her research includes how birth unit design impacts on women and staff stress, communication, and ultimately birth outcomes. Maralyn co-leads the consortium called Birth After Caesarean Interventions which undertakes research promoting normal birth and raising the rate of vaginal birth after caesarean section.

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