course material

1. NUR 641E Advanced Pathophysiology and Pharmacology for Nurse
Educators
NUR 641E Advanced Pathophysiology and Pharmacology for Nurse EducatorsNUR 641E
Advanced Pathophysiology and Pharmacology for Nurse EducatorsPermalink: https://
/nur-641e-advance…-nurse-educators/NUR 641E Advanced Pathophysiology and
Pharmacology for Nurse Educators NUR 641E Week 1 DQ 1 and 2 Find an article on a
genetic disorder and summarize in two or three paragraphs the genetic component causing
the disorder and any multifactorial inheritance components that may contribute to the
disorder. Discuss the usual age of disease onset and if the sex-specific threshold model fits
the disorder. What education could you present to high-risk patients to reduce the risk of
disease onset if a multifactorial component exists? Dq2 Genetic screening has become
widely available to the public including prenatal screening of the fetus in utero to screening
adults for genetic disorders, such as Parkinson’s disease and breast cancer. Share your
thoughts on the legal, ethical, and social implications that may be related to genetic
screening. How would you educate your patient that is considering having genetic
screening? NUR 641E Week 2 DQ 1 and 2 DQ 1 Choose an FDA-approved prescription
medication and discuss the pharmacokinetics and pharmacodynamics of the medication,
including any differences that would be expected based on the patient’s age, a condition of
pregnancy, or lactation. Address any adverse effects the medication may have based on age,
pregnancy, or lactation. DQ2 Active acquired immunity can be achieved through the use of
childhood immunizations. Many parents voice concerns regarding the safety of
vaccinations. What is your opinion on the current use of vaccinations? How would you
educate parents regarding the safety and effectiveness of vaccinations? Defend your
answers with evidence-based research. NUR 641E Week 3 Dq 1 and dq 2 DQ1 Share a case
study of an electrolyte imbalance from your practice or from the literature. Summarize the
case study in 1-2 paragraphs. Then discuss the clinical manifestations of the imbalance, the
pathophysiology behind the imbalance, normal cell membrane transport of the
electrolyte(s), and any alterations in cell membrane transport caused by the imbalance.
How was the electrolyte imbalance resolved? Analyze the case study to determine any areas
in which patient or staff education may have helped to prevent the electrolyte
imbalance.Use at least three scholarly, peer-reviewed resources less than 5 years old in
addition to course materials DQ2 A widespread belief is that caffeine has a diuretic effect
when consumed and will induce dehydration if used by athletes or those who perform

2. strenuous exercise. Discuss the pathophysiology behind this belief. Share your thoughts on
whether you agree or disagree that caffeine can induce dehydration. Support your answer
with evidence-based literature. NUR 641E Week 4 DQ 1 and DQ 2 Compare and contrast
the pathophysiology between chronic obstructive pulmonary disease (COPD) and
pneumococcal pneumonia. Include any types of cellular injury or cellular adaptation that
may occur. Evaluate if an inflammatory response is present and discuss the impact of that
response. In the case of COPD, discuss the type of patient education you would implement to
help with the patient’s understanding of the disease and to improve compliance with a
treatment plan. DQ 2 Find an evidence-based journal article on cystic fibrosis and
summarize the article in one or two paragraphs. Address why you chose the article and how
you might use the findings in your current or future practice setting. NUR 641E Week 5 DQ
1 and DQ 2 DQ 1 Atherosclerosis is a common disorder of the arteries. A modifiable risk
factor for the development of atherosclerosis is hypertension. Discuss the pathophysiology
of both disorders and the mechanisms by which hypertension contributes to
atherosclerosis. Discuss the current medications used to treat both disorders and the
pharmacologic actions the medications have in altering the pathophysiology. How can you
use this information in your current or future practice setting? DQ2 Share a case from
your personal practice or from the literature in which alternative therapies were used to
facilitate the management of acute or chronic cardiovascular conditions. NUR 641E Week 6
DQ 1 and DQ 2 DQ1 Find an article on an inflammatory condition of the lower genitourinary
tract. Summarize the article in one or two paragraphs. Discuss the pathophysiology of the
condition, the pharmacologic agent(s) used to treat the condition, and how the agent(s)
alter the pathophysiology. Discuss the role of the nurse educator related to patient
education of the reported condition and treatment.Respond to another student’s posting on
an inflammatory condition that is different from the condition you posted, comparing and
contrasting the differences between the conditions. DQ 2 Infertility is considered a disease
process of the reproductive tract. Find an article on an alteration of the genital tract that
can lead to infertility. Summarize the article in two or three paragraphs. Discuss any
potential treatments. What is the potential psychosocial impact for the patient with the
condition? NUR 641E Week 7 DQ 1 and DQ 2 Review the following case study:Chief
Complaint:A 23-year-old woman presents with complaints of muscle weakness in the
face.History:The patient is a 23-year-old administrative assistant who complains of
intermittent muscle weakness in her face that has been getting worse over the past 3
months. She also states that as she chews, her jaws feel tired. Swallowing has also become
difficult. She reports episodes of double vision (diplopia), which seems to occur after
reading for a few minutes in the late evening. With certain strenuous activities or after
typing for long periods of time at work, she reports problems with bilateral arm
weakness.Physical Examination:Notable ptosis (drooping) of the eyelids after repeated
blinking exercises. When asked to smile, she appears to be snarling. Reflexes and sensation
are normal in both upper and lower extremities. There is considerable weakness of the
arms noted bilaterally after exercise.Case Questions:Is the patient’s condition neurological,
musculoskeletal, or both? Explain why and support your thoughts with evidence-based
literature. What would be a possible neurologic or musculoskeletal condition causing the

3. symptoms?2.Explain the pathophysiology behind the condition.3.What pharmacological
agent(s) are commonly used to treat the disorder and how do the agent(s) alter the
pathophysiology of the condition?4.What would be your educational plan for the
patient? DQ 2 Parkinson’s disease is a progressive neurodegenerative disorder. The current
treatment options for the disorder have focused on symptom control. Research is now
focusing on developing ways to modify the disease progression and possibly provide a cure.
Investigate the current research on Parkinson’s disease treatments, including stem-cell
research and the use of fetal tissue implants. Share your thoughts on the evolving therapies.
What are the current controversies? NUR 641E Week 8 DQ 1 and DQ 2 DQ 1 Share a case
study from your clinical practice or from the literature on an endocrine disorder. Discuss
the pathophysiology of the disorder, including the effects on the endocrine feedback system,
and the role of the hypothalamic-pituitary axis. Identify the pharmacologic agent(s) used to
treat the disorder and how the pharmacologic agent(s) alters the
pathophysiology. DQ2 Human chorionic gonadotropin (HCG) is currently being used as an
aid to weight loss in conjunction with an extremely restricted caloric intake of 500 calories
per day. Many people are buying the HCG through the Internet with no medical surveillance.
Research the HCG diet and share your thoughts on the efficacy, safety, and validity of the
diet. What strategies would you use to educate patients on the diet? NUR 641E
Week 2 Patient Educational Flyer Design a 1-2 page patient education flyer/pamphlet for
an alternative medicine/herbal product. Describe the product, its intended use, side effects,
adverse reactions, and safety issues (risks and benefits of using an alternative
medication/herbal product versus a prescription medication).The flyer should include at
least two community and/or online resources for the patient to obtain more
information.APA format is not required, but solid academic writing is expected. NUR 641E
Week 3 Acid-Base Case Study PaperRead the “Resource 1: Case Study.” Read below Answer
the questions at the end of the case study in a paper of 750-1,000 words.Prepare this
assignment according to the APA guidelines found in the APA Style Guide, located in the
Student Success Center. An abstract is not required.This assignment uses a rubric. Please
review the rubric prior to beginning the assignment to become familiar with the
expectations for successful completion. Case Study =A 22-year-old woman reports being
“sick with the flu” for the past 8 days. She is vomiting several times every day, having
difficulty keeping liquids or food down, and has been using more than the recommended
dose of antacids in an attempt to calm the nausea. She has become severely dehydrated.
After fainting at home, she was taken to a local hospital. An arterial blood gas sample was
drawn and then an IV was placed to help rehydrate her. The arterial blood gas revealed the
following:Test Result Normal
levelspH 7.5 7.35 –
7.45PaCO2 40 mm Hg 35-45 mm HgPaO2 95
mm Hg 80-100 mm HgSaO2 97% 95-100%HCO3-
32 meq/liter 22-26 meq/liter How would you classify the
patient’s acid-base disturbance and explain why?Given the case study, what are the possible
factors causing this acid-base disturbance? Explain the pathophysiology created by these
factors.How would the renal and respiratory systems try to compensate for this acid-base

4. disturbance?What pharmacologic intervention is commonly used to correct this acid-base
disturbance? Describe the pharmacological actions.Describe the educational needs for this
patient and what your approach will be. NUR 641E Week 4 Patient Interview
Paper Interview a patient with a chronic pulmonary health condition who is on at least two
medications.In a 1,350-1,600-word paper, discuss the following:Obtain a complete health
history.Obtain a complete medication history, including prescription and over-the-counter
drugs or supplements.Analyze the client’s current knowledge level of medications and
compliance with the prescribed dosing and administration.For each medication, identify the
pharmacokinetics, pharmacodynamics, dose, route of administration, side effects, adverse
reactions, any drug interactions, potential safety issues, and the impact on the client’s health
status.Formulate possible interventions related to lack of drug efficacy, lack of client
knowledge, or client compliance issues as identified during the interview.Prepare this
assignment according to the APA guidelines found in the APA Style Guide, located in the
Student Success Center. An abstract is not required. NUR 641E Week 5 (CLC – Staff In-
Service Presentation – Part 1) This is a group assignment. I will instruct the writer as to
which part I am assigned to do.Develop a PowerPoint presentation with complete speaker
notes for a staff in-service on the pathophysiology and pharmacologic agents for a select
disease process. The total maximum number of slides is 30 (Parts 1 and 2 combined). Your
group may determine how to divide the number of slides between Parts 1 and 2.Each CLC
will choose one disease process to present from the following list with the instructor’s
approval:1.Alzheimer’s disease2.Asthma3.Diabetes Type 24.Epilepsy5.Gastroesophageal
reflux disease (GERD)6.Hypertension7.Hypothyroidism8.Multiple sclerosis9.Peptic ulcer
disease10.Tuberculosis. Part 1 of the presentation will focus on the physiology and
pathophysiology of the disease, clinical manifestations, and evaluation (e.g., labs,
imaging).Refer to the resource, “Creating Effective PowerPoint Presentations,” located in
the Student Success Center, for additional guidance on completing this assignment in the
appropriate style. NUR 641E Week 6 Commercial Critique Paper In a 1,200-1,500-word
paper:1.Critique a TV or radio commercial, an Internet advertisement, or a print
advertisement from a nonprofessional journal/magazine related to an FDA-regulated
prescription drug for a gastrointestinal disorder.2.Critique a TV or radio commercial, an
Internet advertisement, or a print advertisement from a nonprofessional journal/magazine
related to a non-FDA-regulated over-the-counter medication/herbal for a gastrointestinal
(GI) disorder.Include a description of the pathophysiology of the GI disorder and how the
medication/herbal alters that pathophysiology.Compare and contrast the two commercials,
including their stated use of medication/herbal, patient safety issues, analysis of company
claims for any drug benefits. Substantiate your thoughts and ideas with evidence-based
research/articles. Prepare this assignment according to the APA guidelines found in the
APA Style Guide, located in the Student Success Center. An abstract is not required. NUR
641E Week 8 CLC – Staff In-Service Presentation – Part 2 This is a Collaborative Learning
Community (CLC) assignment. This is a group assignment. I will instruct the writer as to
which part of the assignment I am assigned.Part 2 of the presentation will focus on the
pharmacologic treatment of the disease, including pharmacokinetics, pharmacodynamics,
drug interactions, side effects, adverse reactions, and application of the nursing process in

5. monitoring the drug therapy.Part 2 will also include the development of a creative patient
education tool for the staff to use to assist in increasing patient knowledge of medications
and medication compliance.The total maximum number of slides is 30 (Parts 1 and 2
combined).An abstract is not required. Part 2 Class Advanced Pathophysiology and
Pharmacology for Nurse Educators: Power Point for Staff In-Service.(Part 2 focuses on the
pharmacologic treatment of the Alzheimer’s disease)Please include speaker notes with all
slides and references (journals preferably)!!!! Focus on the pharmacologic treatment of
Alzheimer’s disease/ Drug Interactions, Side Effects, Adverse Reactions (5-6 slides). Since it
is 6 slides you can do two slides for each underlined section.