Codeine or 3-methylmorphine (a natural isomer of methylated morphine) is an opiate used for its analgesic, antitussive, antidiarrheal, antihypertensive, antianxiety, sedative and hypnotic properties

1. CODEINE
By
Alan Mathew Skaria
TSMU

2. Introduction
• Codeine or 3-methylmorphine is the second-most predominant
alkaloid in opium, at up to three percent.
• Codeine is classified both as a medical and legal narcotic. On its
own, Codeine is a Schedule II drug, but in certain formulations it’s
less strictly-controlled. Although this narcotic medication is very
widely-used, codeine can be highly addictive.

3. History
• Codeine, or 3-methylmorphine, is an alkaloid found in the opium
poppy, Papaver somniferum var. album, a plant in the papaveraceae family. The
name codeine is derived from the Greek word kodeia(κώδεια) for "poppy head".
Opium poppy has been cultivated and utilized throughout human history for a
variety of medicinal (analgesic, anti-tussive and anti-diarrheal) and hypnotic
properties linked to the diversity of its active components, which include
morphine, codeine and papaverine.

4. What Is A Medical Narcotic?
• Codeine meets the medical definition of a narcotic. Narcotics are
a certain family of medications that slow brain activity.
• These are usually used to treat pain or as anesthetics.
• Narcotics can also be used to treat diarrhea or coughing.
• Narcotics can be fatal or have severe adverse effects in large
doses.

5. Narcotic Medical Uses For Codeine
• Codeine can be used to treat mild to moderate pain.
• It’s also used to treat coughing.
• Codeine is often combined with other non-narcotic painkillers, or cough
medications and works by affecting the parts of the brain which control
coughing and pain.

6. Uses:
• Analgesic • Hypnotic properties
• Antitussive • suppress coughing
• Antidiarrheal • Antianxiety
• Antihypertensive • Sedative

7. What Is A Legal Narcotic?
• Sometimes a “narcotic” is used to refer to all illicit substances, but
this is not the legal definition of the term. Legally, a narcotic is a
substance that binds to the opiate receptors of the brain and is
regulated by the Controlled Substances Act. In addition to
opium, opium derivatives, and synthetic opioid substances, the term
can also refer to a few unrelated substances, like cocaine.

8. Why Is Codeine A Schedule II Drug?
• Pure codeine has a high potential for abuse and addiction. It can lead to severe
psychological or physical dependence. However, it’s important to note that not every
drug containing codeine is a Schedule II drug.
• Codeine cough syrups, for example, are only Schedule V, meaning they pose a
limited abuse risk because of the very small amounts of the drug actually contained
in the medication.
• in withdrawal effects; codeine is more difficult to withdraw from than other equally
effective opiate or opioid alternatives.

9. Is Codeine Addictive?
• Yes, codeine is addictive. In fact, codeine is the most widely-used,
naturally-occurring narcotic in the world, making it easier to
access and become addicted to than other, more tightly-controlled
narcotics. However, codeine is more likely to be addictive to
people who have a history of drug or alcohol abuse.

10. Codeine Narcotic Abuse
• Codeine is a narcotic and can be abused for its euphoric effects. Since it’s
usually available only in combination with other medications, this can be
dangerous. Why? These other medications may have a lower threshold for
overdose, and can have their own negative side effects. Codeine overdose is
also possible as a result of codeine abuse.

11. Should Codeine Classification Change?
• No. It seems that the classification of codeine is appropriately
strict for the dangers and addictive potential of the drug. The only
higher rating for narcotic drugs is Schedule I, which is reserved
for substances which are highly addictive and harmful, but which
have no recognized medical use.
• As a Schedule II drug, codeine remains available for those who
really need it.

12. PROs Of Codeine As A Schedule II Narcotic
• Codeine is an effective drug for treating a variety of aliments.
Furthermore, codeine is a good short-term solution for managing pain, and
can help those suffering from cold symptoms which just aren’t eased by over
the counter medications.

13. CONs Of Codeine As A Schedule II Narcotic
• If taken in large enough quantities, codeine can result in overdose, causing coma or death.
Additionally, codeine can have a variety of adverse effects, including:
• constipation
• dizziness
• drowsiness
• headache
• mood changes
• nausea
• vomiting

14. Thank You