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MANY FOLLICLES,
GOOD NUMBER OF
EGGS RETRIEVED,
HIGH AMH LEVEL,
YET NO
PREGNANCY!
020 71966712
• It can be frustrating when you had sizable numbers
of eggs retrieved but only a few eggs matured during
IVF
• IVF process is an advanced fertility treatment, where
every follicle promises to develop an egg, which can
be implanted to yield a pregnancy.
Many Follicles, Good Number Of Eggs Retrieved,
High AMH Level, Yet No Pregnancy!
020 71966712
• Eggs & sperm are an important
component of IVF success but more
relevant are mature eggs &
competent sperm for full term
progeny
IVF Success
020 71966712
• An immature cell should undergo a division of cells by
Meiosis 1 for fertilization to occur.
• To complete meiosis 1, it has to have a high level of
Luteinizing Hormone (LH) in the follicle.
Why Do Some Eggs Not Mature?
020 71966712
•Immature eggs at the egg retrieval stage are the ones
that have not yet reached ‘meiotic competence’. That is,
they have not undergone the first meiotic reduction to the
metaphase II stage (‘M2’) of meiosis.
•In short, they have not yet developed to a stage where
they are capable of undergoing fertilization by sperm.
What Are Immature Eggs?
• Follicles with a diameter of ~16-18mm will
probably have the highest chances of becoming
mature eggs.
• The eggs that are in smaller follicles, don’t
respond to the LH surge and are called immature
ovum.
020 71966712
Why Do Some Eggs Not Mature?
020 71966712
No. Active sperm cannot fertilize immature egg
Without meiosis, the egg or sperm will have
many chromosomes and is incapable of
producing a viable embryo.
Can The Active Sperm Fertilize
An Immature Egg?
020 71966712
Contact Us To Begin Your
Journey To Parenthood Today
If you have same concerns like Many
Follicles, Good Number Of Eggs Retrieved,
High AMH Level, Yet No Pregnancy
Address
Renaissance, J.M. Road, Pune,
Maharashtra, India- 411004.
www.yashivf.com

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Many Follicles, Good Number Of Eggs Retrieved, High AMH Level (2).ppt

  • 1. MANY FOLLICLES, GOOD NUMBER OF EGGS RETRIEVED, HIGH AMH LEVEL, YET NO PREGNANCY!
  • 2. 020 71966712 • It can be frustrating when you had sizable numbers of eggs retrieved but only a few eggs matured during IVF • IVF process is an advanced fertility treatment, where every follicle promises to develop an egg, which can be implanted to yield a pregnancy. Many Follicles, Good Number Of Eggs Retrieved, High AMH Level, Yet No Pregnancy!
  • 3. 020 71966712 • Eggs & sperm are an important component of IVF success but more relevant are mature eggs & competent sperm for full term progeny IVF Success
  • 4. 020 71966712 • An immature cell should undergo a division of cells by Meiosis 1 for fertilization to occur. • To complete meiosis 1, it has to have a high level of Luteinizing Hormone (LH) in the follicle. Why Do Some Eggs Not Mature?
  • 5. 020 71966712 •Immature eggs at the egg retrieval stage are the ones that have not yet reached ‘meiotic competence’. That is, they have not undergone the first meiotic reduction to the metaphase II stage (‘M2’) of meiosis. •In short, they have not yet developed to a stage where they are capable of undergoing fertilization by sperm. What Are Immature Eggs?
  • 6. • Follicles with a diameter of ~16-18mm will probably have the highest chances of becoming mature eggs. • The eggs that are in smaller follicles, don’t respond to the LH surge and are called immature ovum. 020 71966712 Why Do Some Eggs Not Mature?
  • 7. 020 71966712 No. Active sperm cannot fertilize immature egg Without meiosis, the egg or sperm will have many chromosomes and is incapable of producing a viable embryo. Can The Active Sperm Fertilize An Immature Egg?
  • 8. 020 71966712 Contact Us To Begin Your Journey To Parenthood Today If you have same concerns like Many Follicles, Good Number Of Eggs Retrieved, High AMH Level, Yet No Pregnancy Address Renaissance, J.M. Road, Pune, Maharashtra, India- 411004. www.yashivf.com