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3. Nephron sites of action of diuretics

7. Synthesis of acetazolamide Methazolamide Dichlorphenamide

13. Cardiovascular Drugs

17. STRUCTURE OF VASODILATORS Sodium Nitroprusside Hydralazine Purine

20. Captopril Enalapril Lisinopril Ramipril STRUCTURE OF ACE INHIBITORS

24. Verapamil Nimodipine Nicardipine Amlodipine Diltiazem STRUCTURES

27. Structure of Beta- adrenergic agonists Adrenaline Isoprenaline Dopamine Dobutamine Dopexamine

33. Amiodarone Flecainide

34. ANTICOAGULANT AND ANTIPLATELET DRUGS

36. Intrinsic pathway Extrinsic pathway XII XIIa XIa XI IX Ca 2+ IXa PF-3 Ca 2+ VIII Xa Ca 2+ PF-3 V X X III Ca 2+ VIIa  VII Common pathway Prothrombin (factor II) Thrombin XIII XIIIa Fibrinogen Fibrin Stable fibrin polymer

48. SYNTHESIS

49. SYNTHESIS OF ACETAZOLAMIDE

50. CONVERSION OF L-MANNITOL

51. SYNTHESIS OF UREA 2NH3 + CO2 NH2COONH4 ammonium carbamate NH2COONH4 NH2CONH2 + H2O urea

52. Survey

53. SURVEY