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Dr. Steven Muskal
25 years (bio)pharmaceutical industry
’84-‘88 - Engineering Chemistry/Computer
Science (Colorado School of Mines)
’88-’91 - Ph.D. Biophysical Chemistry (UC Berkeley)
’91-‘95 Molecular Design Ltd. (MDL) (Project
manager, BizDev)
’95-’00 Affymax-Glaxo (Unit Director - lead
optimization (ADME), and research computing)
’00-present Eidogen-Sertanty (CEO)
Not Just a Science Geek
Let’s Talk Protein
Building and repair of
body tissues (esp.
muscle)

Enzymatic, hormonal,
inflammatory, and
immune response

Water balance,
nutrient transport,
muscle contraction,
etc.

Energy management,
storage, etc.
Proteins are involved in most everything:
Proteins are “hydrolyzed” in your gut
Your stomach breaks
down proteins into
their amino acid
building blocks
Your genes instruct
protein (re)synthesis
Proteins are reconstructed “on demand”
Your genes
Your microbiome 

(Very important and often overlooked)
e.g. Lactose Intolerance
Whey v. Soy v. Casein
WPI v. WPC v. WPH
What’s in WPI?
Branched-Chain
Amino Acids
(BCAAs)
•Reduce soreness
•Promote recovery
•Increase performance
•Increase the rate of protein
synthesis
“Claims”
Note: Self-administering
certain AA’s have been linked
to Pulmonary Disease (Cys),
Increased Herpes and Viral
Outbreaks, Increased Blood
Pressure (Tyr/Phe), Insulin
Interference (Cys), etc.
Avoid Artificial Sweeteners, 

Use Natural “Cellular-based” Sweeteners
Artificial sweeteners induce glucose intolerance by altering the gut microbiota
(Nature 514, 181–186 9Oct2014)
Try to enjoy with “Superfoods”

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Protein talk 29jan2016

  • 1. Dr. Steven Muskal 25 years (bio)pharmaceutical industry ’84-‘88 - Engineering Chemistry/Computer Science (Colorado School of Mines) ’88-’91 - Ph.D. Biophysical Chemistry (UC Berkeley) ’91-‘95 Molecular Design Ltd. (MDL) (Project manager, BizDev) ’95-’00 Affymax-Glaxo (Unit Director - lead optimization (ADME), and research computing) ’00-present Eidogen-Sertanty (CEO)
  • 2. Not Just a Science Geek
  • 3. Let’s Talk Protein Building and repair of body tissues (esp. muscle) Enzymatic, hormonal, inflammatory, and immune response Water balance, nutrient transport, muscle contraction, etc. Energy management, storage, etc. Proteins are involved in most everything:
  • 4. Proteins are “hydrolyzed” in your gut Your stomach breaks down proteins into their amino acid building blocks Your genes instruct protein (re)synthesis
  • 5. Proteins are reconstructed “on demand” Your genes Your microbiome (Very important and often overlooked) e.g. Lactose Intolerance
  • 6. Whey v. Soy v. Casein
  • 7. WPI v. WPC v. WPH
  • 9. Branched-Chain Amino Acids (BCAAs) •Reduce soreness •Promote recovery •Increase performance •Increase the rate of protein synthesis “Claims” Note: Self-administering certain AA’s have been linked to Pulmonary Disease (Cys), Increased Herpes and Viral Outbreaks, Increased Blood Pressure (Tyr/Phe), Insulin Interference (Cys), etc.
  • 10. Avoid Artificial Sweeteners, Use Natural “Cellular-based” Sweeteners Artificial sweeteners induce glucose intolerance by altering the gut microbiota (Nature 514, 181–186 9Oct2014)
  • 11. Try to enjoy with “Superfoods”