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Prof.S.SUNDAR’S unit Dr.G.Rengaraj.PG
History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Examination ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
DD of sicca symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
INVESTIGATIONS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Inv. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Ophthal op. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
INV. ,[object Object],[object Object],[object Object],[object Object]
Biopsy  ,[object Object],[object Object],[object Object]
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Sjogren’s syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
criteria ,[object Object],[object Object],[object Object],[object Object]
CRITERIA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Criteria  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Picture showing DRY,ERYTHEMATOUS  ORAL  MUCOSA  of the pt ,[object Object]
 
Sjogren’s ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pathogenesis  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical manifestations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
DD of sjogren’s HIV infection & sicca syndrome sjogren’s syn. sarcoidosis Age predominantly young males predominantly in middle-aged women invariable Auto-antibodies - Presence of autoantibodies to Ro/SS-A and/or La/SS-B  -  Histology lymphoid infiltrates of salivary glands by CD8+ lymphocytes Lymphoid infiltrates of salivary glands by CD4+ lymphocytes  granulomas in salivary glands Genetics  Associated with HLA-DR5 Associated with HLA-DR3 & DRw52 unknown  Serology  Positive tests for HIV  Neg. tests Neg. tests
HIV & Sjogren’s ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Treatment  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Secondary sjogren’s ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 

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A Case of Sjogren's Syndrome

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  • 28. DD of sjogren’s HIV infection & sicca syndrome sjogren’s syn. sarcoidosis Age predominantly young males predominantly in middle-aged women invariable Auto-antibodies - Presence of autoantibodies to Ro/SS-A and/or La/SS-B - Histology lymphoid infiltrates of salivary glands by CD8+ lymphocytes Lymphoid infiltrates of salivary glands by CD4+ lymphocytes granulomas in salivary glands Genetics Associated with HLA-DR5 Associated with HLA-DR3 & DRw52 unknown Serology Positive tests for HIV Neg. tests Neg. tests
  • 29.
  • 30.
  • 31.
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  • 33.
  • 34.