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A Case of Idiopathic Pulmonary Hypertension

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Stanley Medical College, Department of Medicine
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Copyright ©2009 American College of Cardiology Foundation. Restrictions may apply. McLaughlin, V. V. et al. J Am Coll Cardiol 2009;53:1573-1619 Relevant Pathways in the Pathogenesis of Pulmonary Arterial Hypertension
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Definition Characteristics Clinical group(s)b Pulmonary hypertension Mean PAP 25 mmHg All Pre-capillary PH Mean PAP 25 mmHg PWP 15 mmHg CO normal or reduced 1. Pulmonary arterial Hypertension 3. PH due to lung diseases 4. Chronic Thromboembolic PH 5. PH with unclear and/or Multifactorial mechanisms Post-capillary PH Passive TPG 12 mmHg Reactive (out of proportion) TPG .12 mmHg Mean PAP 25 mmHg PWP .15 mmHg CO normal or reducedc 2. PH due to left heart disease
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-TYPE NATRIURETIC PEPTIDE Levels of B-type natriuretic peptide (BNP) and N-terminal BNP have been shown to be elevated in patients with IPAH, and levels appear to be prognostic.
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Copyright ©2009 American College of Cardiology Foundation. Restrictions may apply. McLaughlin, V. V. et al. J Am Coll Cardiol 2009;53:1573-1619 Treatment Algorithm for PAH
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A Case of Idiopathic Pulmonary Hypertension

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  • 48. Copyright ©2009 American College of Cardiology Foundation. Restrictions may apply. McLaughlin, V. V. et al. J Am Coll Cardiol 2009;53:1573-1619 Relevant Pathways in the Pathogenesis of Pulmonary Arterial Hypertension
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  • 51. Definition Characteristics Clinical group(s)b Pulmonary hypertension Mean PAP 25 mmHg All Pre-capillary PH Mean PAP 25 mmHg PWP 15 mmHg CO normal or reduced 1. Pulmonary arterial Hypertension 3. PH due to lung diseases 4. Chronic Thromboembolic PH 5. PH with unclear and/or Multifactorial mechanisms Post-capillary PH Passive TPG 12 mmHg Reactive (out of proportion) TPG .12 mmHg Mean PAP 25 mmHg PWP .15 mmHg CO normal or reducedc 2. PH due to left heart disease
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  • 69. -TYPE NATRIURETIC PEPTIDE Levels of B-type natriuretic peptide (BNP) and N-terminal BNP have been shown to be elevated in patients with IPAH, and levels appear to be prognostic.
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  • 76. Copyright ©2009 American College of Cardiology Foundation. Restrictions may apply. McLaughlin, V. V. et al. J Am Coll Cardiol 2009;53:1573-1619 Treatment Algorithm for PAH
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