As much as we love how fun the Ice Bucket Challenge is, we can't stand to watch that the whole meaning of why it exists is lost. Here's why you should care about ALS.
Epilepsy is a neurological condition that causes repeated seizures over time. It is diagnosed when a person experiences at least two seizures that are not caused by a known medical condition. The frequency of seizures in people with epilepsy varies significantly - from years between seizures to daily occurrences. Epilepsy can affect anyone at any age and around 456,000 people in the UK have the condition. Seizures in epilepsy are caused by disturbances in the electrical activity of the brain, though the underlying cause is often unknown.
This document provides an overview of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It defines ALS as a disease that causes the loss of motor neurons in the brain and spinal cord, preventing communication between the brain and muscles and resulting in muscle weakening and atrophy. The document discusses how ALS affects basic functions like walking, eating, and breathing. It notes that while the cause of ALS is unknown, neurotransmitter imbalances may play a role by overstimulating neurons and eventually killing them. The document also provides statistics on ALS prevalence and life expectancy after diagnosis, as well as profiles of famous individuals like Lou Gehrig and Stephen Hawking who lived with ALS.
If you're one of millions of people with at least one form of arthritis or a musculoskeletal disorder (like osteoarthritis, rheumatoid arthritis, psoriatic arthritis, lupus, gout, polymyalgia rheumatica, or ankylosing spondylitis), you have treatment and disease management options. But if your condition is undiagnosed, you could be dealing with inflammation, pain and swelling needlessly. Read these answers and questions about rheumatic diseases and see if they apply to you.
Our vision is to prevent and cure disease and disability of the brain and nervous system through leadership, excellence and innovation in neuroscience research.
Visual Design Basics: The Building Blocks of a Great SlideChiara Ojeda
This document provides tips for improving presentation slides. It suggests making slides more visually appealing by using images, charts, and color to engage the audience. A website is referenced that offers additional resources for learning how to refine slide design and content.
Thirstier - Time is short. We are running out. #drought #California #SaoPaulo...Empowered Presentations
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Epilepsy is a neurological condition that causes repeated seizures over time. It is diagnosed when a person experiences at least two seizures that are not caused by a known medical condition. The frequency of seizures in people with epilepsy varies significantly - from years between seizures to daily occurrences. Epilepsy can affect anyone at any age and around 456,000 people in the UK have the condition. Seizures in epilepsy are caused by disturbances in the electrical activity of the brain, though the underlying cause is often unknown.
This document provides an overview of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It defines ALS as a disease that causes the loss of motor neurons in the brain and spinal cord, preventing communication between the brain and muscles and resulting in muscle weakening and atrophy. The document discusses how ALS affects basic functions like walking, eating, and breathing. It notes that while the cause of ALS is unknown, neurotransmitter imbalances may play a role by overstimulating neurons and eventually killing them. The document also provides statistics on ALS prevalence and life expectancy after diagnosis, as well as profiles of famous individuals like Lou Gehrig and Stephen Hawking who lived with ALS.
If you're one of millions of people with at least one form of arthritis or a musculoskeletal disorder (like osteoarthritis, rheumatoid arthritis, psoriatic arthritis, lupus, gout, polymyalgia rheumatica, or ankylosing spondylitis), you have treatment and disease management options. But if your condition is undiagnosed, you could be dealing with inflammation, pain and swelling needlessly. Read these answers and questions about rheumatic diseases and see if they apply to you.
Our vision is to prevent and cure disease and disability of the brain and nervous system through leadership, excellence and innovation in neuroscience research.
Visual Design Basics: The Building Blocks of a Great SlideChiara Ojeda
This document provides tips for improving presentation slides. It suggests making slides more visually appealing by using images, charts, and color to engage the audience. A website is referenced that offers additional resources for learning how to refine slide design and content.
Thirstier - Time is short. We are running out. #drought #California #SaoPaulo...Empowered Presentations
The document discusses the benefits of exercise for mental health. Regular physical activity can help reduce anxiety and depression and improve mood and cognitive functioning. Exercise causes chemical changes in the brain that may help protect against mental illness and improve symptoms.
Be a social CEO. Share your stories on Linkedin.Slides That Rock
The document encourages CEOs to be more active on social media by sharing stories about their company, colleagues, and customers, like Richard Branson and Andy Barratt do. It argues that having an active CEO presence online helps humanize the brand and builds connections with customers, which can translate to increased sales. The document suggests CEOs commit to sharing three stories on topics related to their company, colleagues, and customers to start becoming a more "social CEO".
This document contains slides from a presentation by Andre Woolery on designing effective presentations by making slides visually appealing. The presentation covers various design elements like fonts, color, composition, shapes, and images that can be manipulated to grab audiences' attention and keep them engaged. It provides examples and tips for using these elements like using bold text or different font sizes to create emphasis, leveraging color to attract the eye or accentuate points, and guiding the viewer's eye through slide composition and alignment.
A major misconception in business is that design should be an afterthought. The (flawed) thinking is that design is not tied to the bottom line, so therefore it should take a back seat to other consideration. We believe the opposite to be true.
Design should be a primary consideration for any business, because it is directly tied to the bottom line. This is a presentation about why design matters.
The document outlines the eight distinctions of a world-class presenter: 1) Get to the point quickly without dramatic distractions. 2) Avoid rambling and keep content concise using less words. 3) Present to persuade by causing changes in mindset, feelings, and behaviors of the audience. 4) Connect with the audience before influencing them by establishing common ground. 5) Sell the "why" of the message before the "what" and "how". 6) Use stories and vivid language to paint pictures in the minds of the audience. 7) Treat the audience as king by helping solve their problems and leaving them better than before. 8) Be authentic rather than polished.
What stops us from making great presentations? Lots of fictonal limits and fears. Let's face 5 common fears and start making awesome slides from now on.
You can learn everything you want about presentations from 74 star decks that we've chosen. Find advice from Garr Reynolds, Emiland de Cubber, Empowered Presentations, Alexei Kapterev and other experts on Slideshare!
How to Use Outstanding Visual Language in a Presentation – Part ISOAP Presentations
http://soappresentations.com/how_to_use_outstanding_visual_language_i/
This e-Book will inspire you to use more visuals in your next presentations, avoiding boring slides with too much text and full of bullet points.
Download the first part of our e-Book, “How to Use Outstanding Visual Language in a Presentation”, and deliver highly impactful messages from now on.
http://soappresentations.com/how_to_use_outstanding_visual_language_i/
Want to make better presentations at work? Here are 12 timeless principles. Applied by Steve Jobs, Elon Musk and other impactful presenters. Use the principles and your audience will love you!
For the one-page guide, go to www.coachbay.com/tools
March's Slideshare offering is all about visual design. Learn why simplicity takes work, why it's best to pair one idea with one slide, why unity matters, why pictures are superior, how losing signal can lose your audience, and a simple method for eliminating slide fluff
The document provides information about the Zika virus outbreak, including how it spreads and symptoms. It notes that Zika virus is mainly spread by Aedes mosquitoes and infected mothers can pass it to fetuses. While there is no vaccine currently, people can protect themselves by preventing mosquito bites, using repellent and eliminating standing water where mosquitoes breed. The most important advice is to stay informed but remain calm.
TEDx events are independently organized local events that bring people together to share ideas in the spirit of TED's mission of spreading ideas. The TEDx program provides guidelines for organizing these events including obtaining a license, choosing a theme, finding speakers, promoting the event, livestreaming options, and reporting back to TED. Organizers are responsible for following TED's guidelines to ensure a quality experience for participants.
This document provides tips and best practices for creating effective presentations using visuals such as shapes, colors, images, and fonts. It recommends starting with a bold cover slide to grab attention, using visuals to highlight key points and sustain audience interest, and ending with a clear call to action. The overall message is that presentations should be visually appealing and easy to understand in order to effectively engage the audience.
Muhammad Ali was a legendary boxer and philanthropist known for his accomplishments in the ring and advocacy outside of it. Some of his notable achievements included being a 3-time heavyweight champion, donating extensively to charitable causes, and sacrificing his title when refusing to fight in the Vietnam war due to his religious beliefs. Ali left behind a legacy of determination, courage in standing up for his principles, and inspiration to achieve one's dreams despite obstacles.
The document provides five design principles for creating slides that effectively communicate messages to audiences:
1. Focus on the main message you want the audience to remember.
2. Keep designs simple with less text and only 1 main point per slide.
3. Use interesting fonts instead of boring standard ones to engage audiences.
4. Include high quality images that visually represent the message.
5. Choose a color scheme that fits the theme and works cohesively.
The document provides examples of standard, boring presentation templates and encourages the creation of unique, visually appealing templates instead. It emphasizes using fewer words and more images per slide, varying fonts and colors, and breaking content into multiple slides to keep audiences engaged. Inspiration sources like design blogs and galleries of infographics and slide designs are recommended for making impactful presentations that attract and impress audiences.
Love reading comics? You're not the only one. What about these stories about super-beings keep our eyes glued to the pages and our minds salivating for more? We explore in this deck how comic writers use these storytelling techniques and how you can apply it in your presentation.
This document discusses amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It notes that ALS is a motor neuron disease that affects voluntary muscle movements and leads to loss of mobility. Most patients die within 5 years of diagnosis as there is no known cure. The document explains that ALS causes the motor neurons that control voluntary muscles like walking, talking, swallowing to deteriorate over time. While breathing may seem involuntary, patients may eventually lose control of this function as well. It highlights recent increased scientific understanding of ALS and FDA-approved drugs that can modestly slow progression, as well as clinical trials of other potential treatments.
ALS ( Amyotrophic Lateral Sclerosis) / Lou Gehrig's DiseaseSiddharthRajah
A PPT made by Siddharth Rajah a biology student in his high school on the deadly nervous disease called ALS. It has affected many people like Stephen Hawking. Want to know more about this? You can see my PPT on it which I made for my Grade 11 Biology Project.
The document discusses several neuromuscular disorders including amyotrophic lateral sclerosis (ALS), multiple sclerosis, and muscular dystrophy. It provides details on ALS such as its symptoms, causes, risk factors, and complications. ALS causes motor neurons to break down and leads to muscle weakness and atrophy. It typically begins in the hands, feet or limbs and eventually affects movement, speech, swallowing and breathing. While most cases have no known cause, genetic mutations and environmental factors may play a role. Complications include breathing and eating problems as well as potential dementia. Tests like EMGs, MRIs and biopsies can help diagnose ALS and rule out other conditions.
21 June: The Global Day for Amyotrophic Lateral Sclerosisguimera
ALS is a progressive neurological disease that causes the motor neurons controlling voluntary muscles to break down and die. This results in worsening muscle weakness, atrophy, and spasticity over time. There is no cure for ALS, but symptoms can be treated to prolong survival and quality of life. The cause is largely unknown, though some genetic factors have been identified. Most people live 3-5 years after diagnosis but about 10% of cases are inherited and can have longer survival times. Research continues toward finding effective treatments that target the underlying causes and pathways of the disease.
Having fun with the ice bucket challenge? Learn more about ALS and spread the word. Contact me to customize this with your office info to distribute to patients and customers!
Be a social CEO. Share your stories on Linkedin.Slides That Rock
The document encourages CEOs to be more active on social media by sharing stories about their company, colleagues, and customers, like Richard Branson and Andy Barratt do. It argues that having an active CEO presence online helps humanize the brand and builds connections with customers, which can translate to increased sales. The document suggests CEOs commit to sharing three stories on topics related to their company, colleagues, and customers to start becoming a more "social CEO".
This document contains slides from a presentation by Andre Woolery on designing effective presentations by making slides visually appealing. The presentation covers various design elements like fonts, color, composition, shapes, and images that can be manipulated to grab audiences' attention and keep them engaged. It provides examples and tips for using these elements like using bold text or different font sizes to create emphasis, leveraging color to attract the eye or accentuate points, and guiding the viewer's eye through slide composition and alignment.
A major misconception in business is that design should be an afterthought. The (flawed) thinking is that design is not tied to the bottom line, so therefore it should take a back seat to other consideration. We believe the opposite to be true.
Design should be a primary consideration for any business, because it is directly tied to the bottom line. This is a presentation about why design matters.
The document outlines the eight distinctions of a world-class presenter: 1) Get to the point quickly without dramatic distractions. 2) Avoid rambling and keep content concise using less words. 3) Present to persuade by causing changes in mindset, feelings, and behaviors of the audience. 4) Connect with the audience before influencing them by establishing common ground. 5) Sell the "why" of the message before the "what" and "how". 6) Use stories and vivid language to paint pictures in the minds of the audience. 7) Treat the audience as king by helping solve their problems and leaving them better than before. 8) Be authentic rather than polished.
What stops us from making great presentations? Lots of fictonal limits and fears. Let's face 5 common fears and start making awesome slides from now on.
You can learn everything you want about presentations from 74 star decks that we've chosen. Find advice from Garr Reynolds, Emiland de Cubber, Empowered Presentations, Alexei Kapterev and other experts on Slideshare!
How to Use Outstanding Visual Language in a Presentation – Part ISOAP Presentations
http://soappresentations.com/how_to_use_outstanding_visual_language_i/
This e-Book will inspire you to use more visuals in your next presentations, avoiding boring slides with too much text and full of bullet points.
Download the first part of our e-Book, “How to Use Outstanding Visual Language in a Presentation”, and deliver highly impactful messages from now on.
http://soappresentations.com/how_to_use_outstanding_visual_language_i/
Want to make better presentations at work? Here are 12 timeless principles. Applied by Steve Jobs, Elon Musk and other impactful presenters. Use the principles and your audience will love you!
For the one-page guide, go to www.coachbay.com/tools
March's Slideshare offering is all about visual design. Learn why simplicity takes work, why it's best to pair one idea with one slide, why unity matters, why pictures are superior, how losing signal can lose your audience, and a simple method for eliminating slide fluff
The document provides information about the Zika virus outbreak, including how it spreads and symptoms. It notes that Zika virus is mainly spread by Aedes mosquitoes and infected mothers can pass it to fetuses. While there is no vaccine currently, people can protect themselves by preventing mosquito bites, using repellent and eliminating standing water where mosquitoes breed. The most important advice is to stay informed but remain calm.
TEDx events are independently organized local events that bring people together to share ideas in the spirit of TED's mission of spreading ideas. The TEDx program provides guidelines for organizing these events including obtaining a license, choosing a theme, finding speakers, promoting the event, livestreaming options, and reporting back to TED. Organizers are responsible for following TED's guidelines to ensure a quality experience for participants.
This document provides tips and best practices for creating effective presentations using visuals such as shapes, colors, images, and fonts. It recommends starting with a bold cover slide to grab attention, using visuals to highlight key points and sustain audience interest, and ending with a clear call to action. The overall message is that presentations should be visually appealing and easy to understand in order to effectively engage the audience.
Muhammad Ali was a legendary boxer and philanthropist known for his accomplishments in the ring and advocacy outside of it. Some of his notable achievements included being a 3-time heavyweight champion, donating extensively to charitable causes, and sacrificing his title when refusing to fight in the Vietnam war due to his religious beliefs. Ali left behind a legacy of determination, courage in standing up for his principles, and inspiration to achieve one's dreams despite obstacles.
The document provides five design principles for creating slides that effectively communicate messages to audiences:
1. Focus on the main message you want the audience to remember.
2. Keep designs simple with less text and only 1 main point per slide.
3. Use interesting fonts instead of boring standard ones to engage audiences.
4. Include high quality images that visually represent the message.
5. Choose a color scheme that fits the theme and works cohesively.
The document provides examples of standard, boring presentation templates and encourages the creation of unique, visually appealing templates instead. It emphasizes using fewer words and more images per slide, varying fonts and colors, and breaking content into multiple slides to keep audiences engaged. Inspiration sources like design blogs and galleries of infographics and slide designs are recommended for making impactful presentations that attract and impress audiences.
Love reading comics? You're not the only one. What about these stories about super-beings keep our eyes glued to the pages and our minds salivating for more? We explore in this deck how comic writers use these storytelling techniques and how you can apply it in your presentation.
This document discusses amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It notes that ALS is a motor neuron disease that affects voluntary muscle movements and leads to loss of mobility. Most patients die within 5 years of diagnosis as there is no known cure. The document explains that ALS causes the motor neurons that control voluntary muscles like walking, talking, swallowing to deteriorate over time. While breathing may seem involuntary, patients may eventually lose control of this function as well. It highlights recent increased scientific understanding of ALS and FDA-approved drugs that can modestly slow progression, as well as clinical trials of other potential treatments.
ALS ( Amyotrophic Lateral Sclerosis) / Lou Gehrig's DiseaseSiddharthRajah
A PPT made by Siddharth Rajah a biology student in his high school on the deadly nervous disease called ALS. It has affected many people like Stephen Hawking. Want to know more about this? You can see my PPT on it which I made for my Grade 11 Biology Project.
The document discusses several neuromuscular disorders including amyotrophic lateral sclerosis (ALS), multiple sclerosis, and muscular dystrophy. It provides details on ALS such as its symptoms, causes, risk factors, and complications. ALS causes motor neurons to break down and leads to muscle weakness and atrophy. It typically begins in the hands, feet or limbs and eventually affects movement, speech, swallowing and breathing. While most cases have no known cause, genetic mutations and environmental factors may play a role. Complications include breathing and eating problems as well as potential dementia. Tests like EMGs, MRIs and biopsies can help diagnose ALS and rule out other conditions.
21 June: The Global Day for Amyotrophic Lateral Sclerosisguimera
ALS is a progressive neurological disease that causes the motor neurons controlling voluntary muscles to break down and die. This results in worsening muscle weakness, atrophy, and spasticity over time. There is no cure for ALS, but symptoms can be treated to prolong survival and quality of life. The cause is largely unknown, though some genetic factors have been identified. Most people live 3-5 years after diagnosis but about 10% of cases are inherited and can have longer survival times. Research continues toward finding effective treatments that target the underlying causes and pathways of the disease.
Having fun with the ice bucket challenge? Learn more about ALS and spread the word. Contact me to customize this with your office info to distribute to patients and customers!
This document provides information about amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. It discusses that ALS is a progressive neurodegenerative disease that affects motor neurons in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually death. Early symptoms can include muscle weakness, twitching, slurred speech, and difficulty breathing. There is no known cure for ALS, but some treatments can help manage symptoms and prolong survival for a few months. Donations can help support research to find an effective treatment for ALS.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal neurological disease that causes progressive muscle weakness and paralysis. The exact causes are unknown but may include genetic and environmental factors. Symptoms start with muscle weakness and progress to include slurred speech, difficulty swallowing, and eventually paralysis of the diaphragm leading to respiratory failure. While there is no cure, treatments can help manage symptoms and some medications may slow disease progression. The average life expectancy is 2-5 years from diagnosis but can vary significantly.
Alzheimer's disease is caused by plaques and tangles in the brain that damage and kill neurons. It usually occurs in older adults as the brain ages, and can run in families with certain gene mutations that increase risk. Symptoms include memory loss, confusion, mood changes, and difficulty communicating. There is no cure, but lifestyle factors like exercise, diet, and mental stimulation may help prevent Alzheimer's or slow its progression. It ultimately results in death, usually due to complications like pneumonia or failure to eat. Alzheimer's has a significant impact on individuals, their families, and society as a whole.
The document provides guidelines for determining hospice eligibility for patients with specific terminal illnesses. It states that to be eligible, patients must meet the guidelines in Section 2, which address general performance status and functional ability, as well as guidelines specific to their disease in Section 3. It then lists common terminal diseases that have additional eligibility guidelines in Section 3.
The document discusses confusion and dementia. It defines confusion and distinguishes it from dementia. Dementia is a decline in functioning that affects areas like memory, decision-making, and language. Alzheimer's disease is the most common type of dementia. The document outlines signs and symptoms of dementia and how it progresses from mild to moderate stages. Potential causes of confusion are also discussed, including physiological factors like brain changes due to aging as well as situational factors like moving to a new environment.
The nervous system and suffixes frequently usedslimgoodee_1966
Aphasia is a language disorder caused by damage to the parts of the brain that control language. It causes difficulties with speaking, reading, writing, and understanding language. There are different types of aphasia depending on whether expressive language (speaking) or receptive language (comprehension) is more impacted. Treatment involves speech therapy to help improve communication skills. Quadriplegia is paralysis of all four limbs and the torso caused by spinal cord injury or other neurological conditions that damage the spinal cord. It results in loss of motor and sensory function below the neck and requires lifelong management of complications. Rehabilitation therapies aim to prevent further neurological damage and help regain functions through techniques like electrical muscle stimulation.
The nervous system and suffixes frequently usedslimgoodee_1966
The document discusses aphasia, which is a language disorder caused by damage to the parts of the brain that control language. It can cause difficulties with speaking, reading, writing, and understanding language. There are different types of aphasia depending on the areas of the brain affected. Aphasia is usually diagnosed through a series of tests and can be treated through speech therapy. The document also provides information on quadriplegia, which is paralysis of all four limbs caused most often by spinal cord injury. It discusses the severity and complications that can result, as well as rehabilitation and treatment options.
The nervous system and suffixes frequently usedslimgoodee_1966
Aphasia is a language disorder caused by damage to the parts of the brain that control language. It causes difficulties with speaking, reading, writing, and understanding language. There are different types of aphasia depending on whether expressive language (speaking) or receptive language (comprehension) is more impacted. Treatment involves speech therapy to help improve communication skills or find alternative methods of expression. Quadriplegia is paralysis of all four limbs and torso caused by spinal cord injury or other neurological conditions that damage the cervical spinal cord. It often leads to loss of bladder and bowel control and risks of respiratory problems, blood clots, and pressure sores that require ongoing management. Rehabilitation focuses on regaining function through therapies and technologies
The nervous system and suffixes frequently usedslimgoodee_1966
Aphasia is a language disorder caused by damage to the parts of the brain that control language. It causes difficulties with speaking, reading, writing, and understanding language. There are different types of aphasia depending on whether expressive language (speaking) or receptive language (comprehension) is more impacted. Treatment involves speech therapy to help improve communication skills or find alternative methods of expression. Quadriplegia is paralysis of all four limbs and torso caused by spinal cord injury or other neurological conditions that damage the cervical spinal cord. It often leads to loss of bladder and bowel control and increased risk of complications like pressure sores, blood clots, and respiratory issues. Rehabilitation focuses on regaining function and independence through therapies and
The nervous system and suffixes frequently usedslimgoodee_1966
Aphasia is a condition that impairs language ability. It is usually caused by stroke or brain injury that damages areas of the brain responsible for language. There are different types of aphasia that vary in severity from mild to severe. Symptoms include difficulty with speaking, word-finding, understanding speech, reading, and writing. Aphasia is diagnosed through neurological tests and treatment involves speech therapy to help improve communication abilities.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a motor neuron disease that affects nerve cells in the brain and spinal cord, causing muscle weakness. As the disease progresses, it causes the loss of function in voluntary muscles as motor neurons degenerate and die, resulting in muscle atrophy. Early symptoms may include twitching or stiffness in muscles, slurred speech, or difficulty swallowing. As the disease worsens, patients experience increasing difficulty with tasks like breathing, speaking, walking, and moving, which can lead to paralysis and eventual death usually within 3-5 years due to respiratory failure.
The document provides information about quadriplegia, including its causes, symptoms, and treatments. It defines quadriplegia as paralysis of both arms and legs caused primarily by spinal cord injuries. Damage to the spinal cord prevents communication between the brain and body. Quadriplegia results in loss of movement, sensation, and control of bodily functions below the neck. Rehabilitation focuses on preventing complications like pressure sores and maintaining muscle and respiratory health through passive exercise and emerging technologies like functional electrical stimulation. Overall treatments aim to manage the condition and improve quality of life.
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a motor neuron disease that affects nerve cells in the brain and spinal cord, causing muscle weakness. As the disease progresses, it causes the loss of function in voluntary muscles as motor neurons degenerate and die, resulting in muscle atrophy. Early symptoms may include twitching or stiffness in muscles, slurred speech, or difficulty swallowing. As the disease worsens, patients experience increasing difficulty with tasks like breathing, speaking, walking, and moving, which can lead to paralysis and eventual death usually within 3-5 years due to respiratory failure.
Heart attacks are one of the leading causes of death in America. With most of us suffering from various kinds of health conditions and adding a lot of extra stress to the heart through our lack of activity and poor eating habits, it is no wonder that many of us are just ticking time bombs before we are able to experience a heart attack ourselves.
Mother Nature has taken hundreds of thousands of years of evolution to develop your heart along with the rest of your body.
Heart attacks are one of the leading causes of death in America. With most of us suffering from various kinds of health conditions and adding a lot of extra stress to the heart through our lack of activity and poor eating habits, it is no wonder that many of us are just ticking time bombs before we are able to experience a heart attack ourselves.
Mother Nature has taken hundreds of thousands of years of evolution to develop your heart along with the rest of your body.
Ähnlich wie Why You Should Care About ALS @slidecomet @itseugenec (20)
Cell Therapy Expansion and Challenges in Autoimmune DiseaseHealth Advances
There is increasing confidence that cell therapies will soon play a role in the treatment of autoimmune disorders, but the extent of this impact remains to be seen. Early readouts on autologous CAR-Ts in lupus are encouraging, but manufacturing and cost limitations are likely to restrict access to highly refractory patients. Allogeneic CAR-Ts have the potential to broaden access to earlier lines of treatment due to their inherent cost benefits, however they will need to demonstrate comparable or improved efficacy to established modalities.
In addition to infrastructure and capacity constraints, CAR-Ts face a very different risk-benefit dynamic in autoimmune compared to oncology, highlighting the need for tolerable therapies with low adverse event risk. CAR-NK and Treg-based therapies are also being developed in certain autoimmune disorders and may demonstrate favorable safety profiles. Several novel non-cell therapies such as bispecific antibodies, nanobodies, and RNAi drugs, may also offer future alternative competitive solutions with variable value propositions.
Widespread adoption of cell therapies will not only require strong efficacy and safety data, but also adapted pricing and access strategies. At oncology-based price points, CAR-Ts are unlikely to achieve broad market access in autoimmune disorders, with eligible patient populations that are potentially orders of magnitude greater than the number of currently addressable cancer patients. Developers have made strides towards reducing cell therapy COGS while improving manufacturing efficiency, but payors will inevitably restrict access until more sustainable pricing is achieved.
Despite these headwinds, industry leaders and investors remain confident that cell therapies are poised to address significant unmet need in patients suffering from autoimmune disorders. However, the extent of this impact on the treatment landscape remains to be seen, as the industry rapidly approaches an inflection point.
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These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
- Video recording of this lecture in English language: https://youtu.be/Pt1nA32sdHQ
- Video recording of this lecture in Arabic language: https://youtu.be/uFdc9F0rlP0
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
share - Lions, tigers, AI and health misinformation, oh my!.pptxTina Purnat
• Pitfalls and pivots needed to use AI effectively in public health
• Evidence-based strategies to address health misinformation effectively
• Building trust with communities online and offline
• Equipping health professionals to address questions, concerns and health misinformation
• Assessing risk and mitigating harm from adverse health narratives in communities, health workforce and health system
12. your muscles lose function
you can’t speak properly
you have trouble in the toilet
you can’t eat or
breathe properly
What could happen
in non ‘sciencey’ terms
you can’t feel your arms
you can’t walk
13. Imagine if you couldn’t:
Eat Breathe
Walk
Button Your Shirt
anymore..
Talk
Kiss your loved one
Use the bathroomImage Source: ALS Society of Manitoba
14. No more..
Walking by the beach
Saying “I love you”
Munching on your fries
Taking a supreme dump
Meeting up with friends
Hugging someone