This document discusses the complications of acute and chronic pancreatitis. For acute pancreatitis, local complications include pseudocysts, fat necrosis, and systemic inflammatory response syndrome. Pseudocysts are walled-off fluid collections that can rupture and cause peritonitis. Fat necrosis indicates a poor prognosis and can lead to hypocalcemia. Systemic complications of acute pancreatitis include acute respiratory distress syndrome, disseminated intravascular coagulation, and multiple organ failure. Chronic pancreatitis complications involve the pancreas and surrounding areas, leading to pancreatic insufficiency, diabetes, and splenic vein thrombosis which can cause gastric varices and bleeding.