The comma operator has two uses - as a separator and as an operator. As a separator, it is used to separate expressions, variable declarations, function calls, and other items. As an operator, it evaluates the first operand and discards the result, then evaluates the second operand and returns its value. It has the lowest precedence of any C operator and associates from left to right. The document provides several examples demonstrating the comma operator's usage and precedence relative to other operators like assignment, brackets, and semicolons.