This document discusses colorectal cancer. Some key points:
- It is the 3rd most common cancer globally and incidence is increasing in developing countries. Risk factors include family history, inflammatory bowel diseases, and diet.
- Most cases arise from adenomatous polyps through genetic mutations over many years. Symptoms often only appear once cancer has spread.
- Diagnosis is made through colonoscopy and biopsy. Staging involves assessing tumor size, lymph node involvement, and metastasis.
- Treatment depends on cancer location and staging, and may include surgery, chemotherapy, and targeted therapies. Screening can detect early-stage cancers when more readily treatable.
The document provides information on colon cancer including:
1. The blood supply, lymphatic drainage, and innervation of the colon.
2. Risk factors for colon cancer development including familial syndromes.
3. Staging systems for colon cancer such as Dukes classification and TNM staging.
4. Clinical features, diagnosis, and screening guidelines for colon cancer.
Gastric adenocarcinoma is the most common type of gastric cancer, comprising over 90% of cases. Risk factors include H. pylori infection, smoking, low fruit/vegetable diet, and family history. It is classified based on location, growth pattern (intestinal or diffuse), and depth of invasion. Early detection through screening endoscopy offers the best chance of cure via surgical resection, with 5-year survival rates over 90% for early cancer but below 20% for advanced cases.
Gastric adenocarcinoma is the most common type of gastric cancer, comprising over 90% of cases. Risk factors include H. pylori infection, smoking, low fruit/vegetable diet, and family history. It is classified based on depth of invasion, growth pattern (exophytic, flat, excavated), and histology (intestinal or diffuse). Diagnosis involves endoscopy with biopsy. Treatment depends on stage but may include surgery, chemotherapy, and radiation. Early detection through screening programs improves 5-year survival rates from below 20% for advanced cases to over 90% for early gastric cancer.
Colon cancer is the third most common malignancy worldwide. It typically presents in individuals over 50 years of age with symptoms like weight loss, anemia, abdominal discomfort, and rectal bleeding. Diagnosis involves blood tests, imaging like CT scan to evaluate the colon and detect metastasis, and colonoscopy to directly visualize the colon and perform biopsies. Staging uses the TNM system and determines appropriate treatment and prognosis.
Carcinoma of the gallbladder is the most common malignancy of the extrahepatic biliary tract. It occurs most frequently in the seventh decade of life and has a poor 5-year survival rate of around 5-12% despite surgical intervention. The most important risk factor is gallstones, present in 95% of cases. Carcinomas of the gallbladder show infiltrating or exophytic patterns of growth and are usually adenocarcinomas, though some are squamous cell carcinomas. They typically invade the liver and involve lymph nodes by the time of discovery.
Colon cancer typically begins as a noncancerous polyp in the lining of the colon or rectum and can become cancerous over time. Risk factors include age, family history, diet high in red meat and saturated fats, obesity, smoking, and alcohol use. Screening is important, as early detection improves outcomes - average risk adults should be screened beginning at age 50. Colon cancer is staged based on how far it has spread, with treatment options including surgery, chemotherapy, and radiation depending on the stage. While early stage cancers can often be cured with surgery alone, advanced cancers are difficult to treat and the goals shift to slowing growth and managing symptoms.
CARCINOMA STOMACH
INCIDENCE
‘It is the captain of men of death’.
It is more common in Japan—70 per 1,00,000 population.
It is more common in males 2:1.
Decrease incidence in western world
The document provides information on colon cancer including:
1. The blood supply, lymphatic drainage, and innervation of the colon.
2. Risk factors for colon cancer development including familial syndromes.
3. Staging systems for colon cancer such as Dukes classification and TNM staging.
4. Clinical features, diagnosis, and screening guidelines for colon cancer.
Gastric adenocarcinoma is the most common type of gastric cancer, comprising over 90% of cases. Risk factors include H. pylori infection, smoking, low fruit/vegetable diet, and family history. It is classified based on location, growth pattern (intestinal or diffuse), and depth of invasion. Early detection through screening endoscopy offers the best chance of cure via surgical resection, with 5-year survival rates over 90% for early cancer but below 20% for advanced cases.
Gastric adenocarcinoma is the most common type of gastric cancer, comprising over 90% of cases. Risk factors include H. pylori infection, smoking, low fruit/vegetable diet, and family history. It is classified based on depth of invasion, growth pattern (exophytic, flat, excavated), and histology (intestinal or diffuse). Diagnosis involves endoscopy with biopsy. Treatment depends on stage but may include surgery, chemotherapy, and radiation. Early detection through screening programs improves 5-year survival rates from below 20% for advanced cases to over 90% for early gastric cancer.
Colon cancer is the third most common malignancy worldwide. It typically presents in individuals over 50 years of age with symptoms like weight loss, anemia, abdominal discomfort, and rectal bleeding. Diagnosis involves blood tests, imaging like CT scan to evaluate the colon and detect metastasis, and colonoscopy to directly visualize the colon and perform biopsies. Staging uses the TNM system and determines appropriate treatment and prognosis.
Carcinoma of the gallbladder is the most common malignancy of the extrahepatic biliary tract. It occurs most frequently in the seventh decade of life and has a poor 5-year survival rate of around 5-12% despite surgical intervention. The most important risk factor is gallstones, present in 95% of cases. Carcinomas of the gallbladder show infiltrating or exophytic patterns of growth and are usually adenocarcinomas, though some are squamous cell carcinomas. They typically invade the liver and involve lymph nodes by the time of discovery.
Colon cancer typically begins as a noncancerous polyp in the lining of the colon or rectum and can become cancerous over time. Risk factors include age, family history, diet high in red meat and saturated fats, obesity, smoking, and alcohol use. Screening is important, as early detection improves outcomes - average risk adults should be screened beginning at age 50. Colon cancer is staged based on how far it has spread, with treatment options including surgery, chemotherapy, and radiation depending on the stage. While early stage cancers can often be cured with surgery alone, advanced cancers are difficult to treat and the goals shift to slowing growth and managing symptoms.
CARCINOMA STOMACH
INCIDENCE
‘It is the captain of men of death’.
It is more common in Japan—70 per 1,00,000 population.
It is more common in males 2:1.
Decrease incidence in western world
Gastric adenocarcinoma is the most common type of stomach cancer, comprising over 90% of cases. Risk factors include H. pylori infection, smoking, low fruit/vegetable diet, and family history. It is classified based on growth pattern (exophytic, flat, excavated), depth of invasion (early vs. advanced), and histology (intestinal vs. diffuse). Early detection through screening endoscopy and surgical resection offer the best chance of cure, with 5-year survival rates over 90% for early cancer but below 20% for advanced cases. Prevention focuses on modifiable lifestyle risk factors and mass endoscopic screening programs.
This document provides information on carcinoma of the colon, including:
- Risk factors include red meat consumption, smoking, alcohol, certain medical conditions, and lack of protective factors like dietary fiber and aspirin.
- Most colorectal cancers develop through the adenoma-carcinoma sequence, where benign polyps transform into malignant carcinomas over time.
- Screening methods like colonoscopy can detect and remove precancerous polyps, reducing colorectal cancer incidence.
This document provides an overview of colorectal cancer. It discusses that colorectal cancer is the third most common cancer globally. The document outlines the anatomy of the colon and risk factors for colorectal cancer such as pre-cancerous conditions, hereditary syndromes, diet, radiation exposure and surgeries. It also describes the pathology, clinical presentation, investigations and treatments for colorectal cancer. Staging systems including Duke's and TNM classification are summarized. The document concludes with an overview of how colorectal cancer spreads.
Oesophageal cancer is the 14th most common malignancy in the UK. There are two major types - squamous cell carcinoma and adenocarcinoma. The main risk factors are smoking, alcohol consumption, and chronic reflux. Symptoms include dysphagia. Diagnosis involves endoscopy with biopsies. Treatment depends on staging and may include surgery, chemotherapy, radiotherapy, or palliative care. Prognosis is poor with a 5-year survival of around 16% but depends on stage, with early-stage disease having a better prognosis if treated.
A 30-year-old female presented with a one month history of left iliac fossa pain, anorexia, weight loss, and vomiting for one week. Examination revealed a tender palpable mass in the left iliac fossa. CT scan showed sigmoid colon cancer with liver metastases. At laparotomy, a perforated sigmoid colon mass was found adhered to surrounding structures with pus collection. A sigmoid colectomy with end colostomy was performed.
This document discusses gallbladder tumors and cancer. It covers the epidemiology, etiology, pathology, clinical presentation, and radiologic investigation of gallbladder cancer. The key points are:
- Gallbladder cancer is the sixth most common cancer of the gastrointestinal tract. Surgical removal is the only potentially curative treatment but long-term survival is limited due to late diagnosis and early spread.
- Risk factors include chronic gallbladder inflammation from conditions like cholelithiasis. Tumors often invade locally into the liver and spread via lymph nodes and blood vessels at an early stage.
- Clinical presentation can include right upper quadrant pain, weight loss, jaundice, or an incidental finding after ch
This document summarizes information about gastric carcinoma (stomach cancer). It covers the epidemiology, anatomy, pathology, risk factors, clinical presentation, staging, and treatment of gastric cancer. Key points include:
- Gastric cancer was previously a leading cause of cancer death but now ranks fourth most common. Incidence is highest in China and Japan.
- The stomach has extensive lymphatic drainage involving 16 lymph node stations.
- 95% of gastric cancers are adenocarcinomas. Other rare types include squamous cell carcinoma and carcinoid tumors.
- Risk factors include smoking, obesity, and H. pylori infection. Symptoms are often vague but may include weight loss, abdominal pain,
Gastric carcinoma is the major cause of mortality worldwide. It is more common in males than females and incidence peaks between 50-70 years of age. Risk factors include H. pylori infection, smoking, low socioeconomic status, and family history. Histologically, adenocarcinoma accounts for 90% of cases. Early detection is key to improving outcomes, as resection surgery can potentially cure localized disease, but prognosis is generally poor.
This document provides information on gastric carcinoma, including:
1. It describes the classification, epidemiology, risk factors, pathogenesis, histology, staging, clinical features, investigations, and management of gastric adenocarcinoma.
2. The main risk factors include H. pylori infection, dietary nitrites, genetic mutations, and polyps. Gastric adenocarcinoma is classified based on cell type, location, depth of invasion, and metastasis.
3. Management involves endoscopic resection for early cancers, while advanced cancers are treated with surgery such as gastrectomy, with or without chemotherapy and radiotherapy. Complications and palliative care are also discussed.
1. The document discusses several gastrointestinal malignancies including cancer of the stomach, pancreas, and esophagus.
2. It provides details on the types, risk factors, clinical features, diagnosis, staging, and treatment options for each cancer type.
3. The prognosis for pancreatic and esophageal cancers is generally poor, as they often present at late stages and have low 5-year survival rates, while treatments for stomach cancers include surgical resection and chemotherapy or radiation depending on the stage and location of cancer.
Squamous cell carcinoma and adenocarcinoma are the two main types of esophageal cancer. Squamous cell carcinoma makes up about 90% of cases and is usually located in the upper two-thirds of the esophagus. Adenocarcinoma is more common in Western countries and usually arises from Barrett's esophagus in the lower third. Risk factors include tobacco and alcohol use for squamous cell carcinoma and obesity and gastroesophageal reflux for adenocarcinoma. Both types often present with dysphagia and have poor prognosis due to advanced stage at diagnosis.
Small intestinal cancers are rare but increasing in incidence. The four main subtypes are adenocarcinomas, neuroendocrine tumors, gastrointestinal stromal tumors, and lymphomas. Adenocarcinomas and carcinoid tumors are the most common. Risk factors include hereditary conditions and diseases like celiac disease and Crohn's. Tumors are staged using the TNM system and treated with surgery though chemotherapy may be used for lymphomas. Prognosis depends on factors like lymph node involvement and primary tumor location.
This document discusses carcinoma of the esophagus. It notes that squamous cell carcinoma is the most common worldwide and is associated with smoking, alcohol, and nutritional deficiencies. Adenocarcinoma is more common in Western countries and is linked to gastroesophageal reflux disease and obesity. Symptoms include dysphagia and weight loss. Diagnosis involves endoscopy with biopsy. Staging utilizes CT, PET scans, and endoscopic ultrasound to evaluate extent of disease.
Colorectal cancer is the third most common cancer and second leading cause of cancer death. It begins as a noncancerous polyp that over time can become cancerous. Risk factors include polyps, age, inflammatory bowel disease, diet high in red meat, family history, obesity, smoking, and alcohol. Genetic and environmental factors both contribute to development. Screening is recommended for those over 50 or those with family history. Treatment depends on stage - early stage is often surgery while later stages involve chemotherapy, radiation, and surgery. Goals are to remove cancer, kill remaining cells, and prevent return in early stages or slow growth and manage symptoms in advanced cancer.
Gastric cancer is a major cause of cancer mortality worldwide. Risk factors include H. pylori infection, older age, smoking, and diets high in smoked/salted foods. Diagnosis involves endoscopy with biopsy. Staging uses TNM classification and evaluates tumor invasion depth, lymph node involvement, and distant metastasis. Treatment depends on stage but may include surgery, chemotherapy, and radiation. Prognosis is best for early stage cancers that can be completely surgically resected.
Gastric tumors can be classified according to their blood supply, lymphatic drainage patterns, and histologic subtypes. Gastric adenocarcinoma is a major cause of cancer mortality worldwide. Early diagnosis is key to successfully treating gastric cancer before it spreads. Endoscopic evaluation and biopsy are important for diagnostic evaluation and staging of gastric tumors.
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
Mental Health and well-being Presentation. Exploring innovative approaches and strategies for enhancing mental well-being. Discover cutting-edge research, effective strategies, and practical methods for fostering mental well-being.
Weitere ähnliche Inhalte
Ähnlich wie COLORECTAL CANCER by Dr. Oyintonbra Koroye pptx
Gastric adenocarcinoma is the most common type of stomach cancer, comprising over 90% of cases. Risk factors include H. pylori infection, smoking, low fruit/vegetable diet, and family history. It is classified based on growth pattern (exophytic, flat, excavated), depth of invasion (early vs. advanced), and histology (intestinal vs. diffuse). Early detection through screening endoscopy and surgical resection offer the best chance of cure, with 5-year survival rates over 90% for early cancer but below 20% for advanced cases. Prevention focuses on modifiable lifestyle risk factors and mass endoscopic screening programs.
This document provides information on carcinoma of the colon, including:
- Risk factors include red meat consumption, smoking, alcohol, certain medical conditions, and lack of protective factors like dietary fiber and aspirin.
- Most colorectal cancers develop through the adenoma-carcinoma sequence, where benign polyps transform into malignant carcinomas over time.
- Screening methods like colonoscopy can detect and remove precancerous polyps, reducing colorectal cancer incidence.
This document provides an overview of colorectal cancer. It discusses that colorectal cancer is the third most common cancer globally. The document outlines the anatomy of the colon and risk factors for colorectal cancer such as pre-cancerous conditions, hereditary syndromes, diet, radiation exposure and surgeries. It also describes the pathology, clinical presentation, investigations and treatments for colorectal cancer. Staging systems including Duke's and TNM classification are summarized. The document concludes with an overview of how colorectal cancer spreads.
Oesophageal cancer is the 14th most common malignancy in the UK. There are two major types - squamous cell carcinoma and adenocarcinoma. The main risk factors are smoking, alcohol consumption, and chronic reflux. Symptoms include dysphagia. Diagnosis involves endoscopy with biopsies. Treatment depends on staging and may include surgery, chemotherapy, radiotherapy, or palliative care. Prognosis is poor with a 5-year survival of around 16% but depends on stage, with early-stage disease having a better prognosis if treated.
A 30-year-old female presented with a one month history of left iliac fossa pain, anorexia, weight loss, and vomiting for one week. Examination revealed a tender palpable mass in the left iliac fossa. CT scan showed sigmoid colon cancer with liver metastases. At laparotomy, a perforated sigmoid colon mass was found adhered to surrounding structures with pus collection. A sigmoid colectomy with end colostomy was performed.
This document discusses gallbladder tumors and cancer. It covers the epidemiology, etiology, pathology, clinical presentation, and radiologic investigation of gallbladder cancer. The key points are:
- Gallbladder cancer is the sixth most common cancer of the gastrointestinal tract. Surgical removal is the only potentially curative treatment but long-term survival is limited due to late diagnosis and early spread.
- Risk factors include chronic gallbladder inflammation from conditions like cholelithiasis. Tumors often invade locally into the liver and spread via lymph nodes and blood vessels at an early stage.
- Clinical presentation can include right upper quadrant pain, weight loss, jaundice, or an incidental finding after ch
This document summarizes information about gastric carcinoma (stomach cancer). It covers the epidemiology, anatomy, pathology, risk factors, clinical presentation, staging, and treatment of gastric cancer. Key points include:
- Gastric cancer was previously a leading cause of cancer death but now ranks fourth most common. Incidence is highest in China and Japan.
- The stomach has extensive lymphatic drainage involving 16 lymph node stations.
- 95% of gastric cancers are adenocarcinomas. Other rare types include squamous cell carcinoma and carcinoid tumors.
- Risk factors include smoking, obesity, and H. pylori infection. Symptoms are often vague but may include weight loss, abdominal pain,
Gastric carcinoma is the major cause of mortality worldwide. It is more common in males than females and incidence peaks between 50-70 years of age. Risk factors include H. pylori infection, smoking, low socioeconomic status, and family history. Histologically, adenocarcinoma accounts for 90% of cases. Early detection is key to improving outcomes, as resection surgery can potentially cure localized disease, but prognosis is generally poor.
This document provides information on gastric carcinoma, including:
1. It describes the classification, epidemiology, risk factors, pathogenesis, histology, staging, clinical features, investigations, and management of gastric adenocarcinoma.
2. The main risk factors include H. pylori infection, dietary nitrites, genetic mutations, and polyps. Gastric adenocarcinoma is classified based on cell type, location, depth of invasion, and metastasis.
3. Management involves endoscopic resection for early cancers, while advanced cancers are treated with surgery such as gastrectomy, with or without chemotherapy and radiotherapy. Complications and palliative care are also discussed.
1. The document discusses several gastrointestinal malignancies including cancer of the stomach, pancreas, and esophagus.
2. It provides details on the types, risk factors, clinical features, diagnosis, staging, and treatment options for each cancer type.
3. The prognosis for pancreatic and esophageal cancers is generally poor, as they often present at late stages and have low 5-year survival rates, while treatments for stomach cancers include surgical resection and chemotherapy or radiation depending on the stage and location of cancer.
Squamous cell carcinoma and adenocarcinoma are the two main types of esophageal cancer. Squamous cell carcinoma makes up about 90% of cases and is usually located in the upper two-thirds of the esophagus. Adenocarcinoma is more common in Western countries and usually arises from Barrett's esophagus in the lower third. Risk factors include tobacco and alcohol use for squamous cell carcinoma and obesity and gastroesophageal reflux for adenocarcinoma. Both types often present with dysphagia and have poor prognosis due to advanced stage at diagnosis.
Small intestinal cancers are rare but increasing in incidence. The four main subtypes are adenocarcinomas, neuroendocrine tumors, gastrointestinal stromal tumors, and lymphomas. Adenocarcinomas and carcinoid tumors are the most common. Risk factors include hereditary conditions and diseases like celiac disease and Crohn's. Tumors are staged using the TNM system and treated with surgery though chemotherapy may be used for lymphomas. Prognosis depends on factors like lymph node involvement and primary tumor location.
This document discusses carcinoma of the esophagus. It notes that squamous cell carcinoma is the most common worldwide and is associated with smoking, alcohol, and nutritional deficiencies. Adenocarcinoma is more common in Western countries and is linked to gastroesophageal reflux disease and obesity. Symptoms include dysphagia and weight loss. Diagnosis involves endoscopy with biopsy. Staging utilizes CT, PET scans, and endoscopic ultrasound to evaluate extent of disease.
Colorectal cancer is the third most common cancer and second leading cause of cancer death. It begins as a noncancerous polyp that over time can become cancerous. Risk factors include polyps, age, inflammatory bowel disease, diet high in red meat, family history, obesity, smoking, and alcohol. Genetic and environmental factors both contribute to development. Screening is recommended for those over 50 or those with family history. Treatment depends on stage - early stage is often surgery while later stages involve chemotherapy, radiation, and surgery. Goals are to remove cancer, kill remaining cells, and prevent return in early stages or slow growth and manage symptoms in advanced cancer.
Gastric cancer is a major cause of cancer mortality worldwide. Risk factors include H. pylori infection, older age, smoking, and diets high in smoked/salted foods. Diagnosis involves endoscopy with biopsy. Staging uses TNM classification and evaluates tumor invasion depth, lymph node involvement, and distant metastasis. Treatment depends on stage but may include surgery, chemotherapy, and radiation. Prognosis is best for early stage cancers that can be completely surgically resected.
Gastric tumors can be classified according to their blood supply, lymphatic drainage patterns, and histologic subtypes. Gastric adenocarcinoma is a major cause of cancer mortality worldwide. Early diagnosis is key to successfully treating gastric cancer before it spreads. Endoscopic evaluation and biopsy are important for diagnostic evaluation and staging of gastric tumors.
Ähnlich wie COLORECTAL CANCER by Dr. Oyintonbra Koroye pptx (20)
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
Mental Health and well-being Presentation. Exploring innovative approaches and strategies for enhancing mental well-being. Discover cutting-edge research, effective strategies, and practical methods for fostering mental well-being.
This particular slides consist of- what is Pneumothorax,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is a summary of Pneumothorax:
Pneumothorax, also known as a collapsed lung, is a condition that occurs when air leaks into the space between the lung and chest wall. This air buildup puts pressure on the lung, preventing it from expanding fully when you breathe. A pneumothorax can cause a complete or partial collapse of the lung.
The Importance of Black Women Understanding the Chemicals in Their Personal C...bkling
Certain chemicals, such as phthalates and parabens, can disrupt the body's hormones and have significant effects on health. According to data, hormone-related health issues such as uterine fibroids, infertility, early puberty and more aggressive forms of breast and endometrial cancers disproportionately affect Black women. Our guest speaker, Jasmine A. McDonald, PhD, an Assistant Professor in the Department of Epidemiology at Columbia University in New York City, discusses the scientific reasons why Black women should pay attention to specific chemicals in their personal care products, like hair care, and ways to minimize their exposure.
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.
NURSING MANAGEMENT OF PATIENT WITH EMPHYSEMA .PPTblessyjannu21
Prepared by Prof. BLESSY THOMAS, VICE PRINCIPAL, FNCON, SPN.
Emphysema is a disease condition of respiratory system.
Emphysema is an abnormal permanent enlargement of the air spaces distal to terminal bronchioles, accompanied by destruction of their walls and without obvious fibrosis.
Emphysema of lung is defined as hyper inflation of the lung ais spaces due to obstruction of non respiratory bronchioles as due to loss of elasticity of alveoli.
It is a type of chronic obstructive
pulmonary disease.
It is a progressive disease of lungs.
At Malayali Kerala Spa Ajman, Full Service includes individualized care for every client. We specifically design each massage session for the individual needs of the client. Our therapists are always willing to adjust the treatments based on the client's instruction and feedback. This guarantees that every client receives the treatment they expect.
By offering a variety of massage services, our Ajman Spa Massage Center can tackle physical, mental, and emotional illnesses. In addition, efficient identification of specific health conditions and designing treatment plans accordingly can significantly enhance the quality of massaging.
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If you are interested in experiencing transformative massage treatment at Malayali Kerala Spa Ajman, you can use our Ajman Massage Center WhatsApp Number to schedule your next massage session.
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Hypertension and it's role of physiotherapy in it.Vishal kr Thakur
This particular slides consist of- what is hypertension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is summary of hypertension -
Hypertension, also known as high blood pressure, is a serious medical condition that occurs when blood pressure in the body's arteries is consistently too high. Blood pressure is the force of blood pushing against the walls of blood vessels as the heart pumps it. Hypertension can increase the risk of heart disease, brain disease, kidney disease, and premature death.
CHAPTER 1 SEMESTER V COMMUNICATION TECHNIQUES FOR CHILDREN.pdfSachin Sharma
Here are some key objectives of communication with children:
Build Trust and Security:
Establish a safe and supportive environment where children feel comfortable expressing themselves.
Encourage Expression:
Enable children to articulate their thoughts, feelings, and experiences.
Promote Emotional Understanding:
Help children identify and understand their own emotions and the emotions of others.
Enhance Listening Skills:
Develop children’s ability to listen attentively and respond appropriately.
Foster Positive Relationships:
Strengthen the bond between children and caregivers, peers, and other adults.
Support Learning and Development:
Aid cognitive and language development through engaging and meaningful conversations.
Teach Social Skills:
Encourage polite, respectful, and empathetic interactions with others.
Resolve Conflicts:
Provide tools and guidance for children to handle disagreements constructively.
Encourage Independence:
Support children in making decisions and solving problems on their own.
Provide Reassurance and Comfort:
Offer comfort and understanding during times of distress or uncertainty.
Reinforce Positive Behavior:
Acknowledge and encourage positive actions and behaviors.
Guide and Educate:
Offer clear instructions and explanations to help children understand expectations and learn new concepts.
By focusing on these objectives, communication with children can be both effective and nurturing, supporting their overall growth and well-being.
2. EPIDEMIOLOGY
• 3rd commonest malignancy after lung and
stomach in males and breast and cervix in
women
• Constitutes 8.8% of cancers in males and 9.2%
in females
• In Western communities it’s the 2nd
commonest malignancy
• 10 times commoner in developed countries
• Incidence in black Africa is increasing
3. EPIDEMIOLOGY contd
• Ca rectum is commoner in males 2:1
• Colon cancer is commoner in females 11:7
• Peak age of occurrence is 60-79 years
• Half of the cases occor above 60 years
• 20% occur before 50 years
4. DISTRIBUTION ACCORDING TO SITE
• 12% of large bowel malignancy occurs in the
caecum and ascending colon
• Rectum and pelvirectal junction is commonest
site, 60%
• Descending colon is least affected site, 3%
5.
6. • Rarity of pre cancerous conditions
• The young age of the population
• Transit time of feces and fibre diet
8. ADENOMAS
.Established adenoma-carcinoma sequence of 5 to 15 years
.The propensity for development of carcinoma depends on
its size, type and degree of dysplasia
FAMILIAL ADENOMATOUS POLYPOSIS(FAP)
.Accounts for 1% of colorectal cancer
.75% of pxs with FAP develop carcinoma if left untreated
.Need for screening of relatives with colonoscopy and gene
testing
9. .FAP syndromes include Gardners , Oldfield and Turcot
syndromes
ULCERATIVE COLITIS; malignancy is more likely to occur
if
.Duration of illness > 10 years
.Pancolonic involvement
.Young age at onset
Patients with ulcerative colitis are 30 times more likely
to develop colorectal cancer
10. • CROHNS DISEASE
.20 fold increase in developing carcinoma
• HEREDITARY NON POLYPOSIS COLORECTAL
SYNDROMES; accounts for 5 to 10% of colorectal
carcinoma
.LYNCH 1 is site specific and predisposes to ca colon
only
.LYNCH 2 aka cancer family syndrome. Patients or their
family members develop carcinoma of the colorectum,
breast, uterus or stomach. Inherited autosomal
dominantly
11. • FIRST DEGREE RELATIVES
.Theres a 3 to 4 times increased risk of developing
colorectal carcinoma
• DIET
.Increased intake of saturated fats
.Increased intake of refined sugars and red meat
.low fibre diet
.Refined diets lack vitamins A, C and E
15. PATHOLOGY
MACROSCOPICALLY there are 4 variants
.CAULIFLOWER, PROLIFERATIVE or FUNGATING
.MALIGNANT ULCER
.ANNULAR, SCIRRHOUS or STRING STRICTURE
.TUBULAR or INFILTRATIVE
MICROSCOPICALLY ; most are adenocarcinoma.
Others are anaplastic ca and colloid ca
18. SPREAD
• DIRECT
.Commoner with the ulcerative variant
.Transverse or longitudinal spread
.May erode adjacent organs causing fistulae eg
colovesical, colouterine, rectovaginal etc
• LYMPHATIC SPREAD; N1, N2 and N3
.Occurs in 2% of colorectal ca
.Metastasis may lodge in lymph vessels of mesorectum
.Degree of spread correlates with degree of intestinal
wall penetration and histological type
19. SPREAD contd
• BLOOD
.Causes 30 to 40% of late deaths
.Spread is via inf and sup mesenteric and
portal veins
• TRANSPERITONEAL SEEDLING, seedlings may
become implanted on viscera or peritoneum
(car
20. GRADING
• GRADING refers to the degree of
differentiation of the cancer cells ie how much
they resemble normal cells of colorectum. The
better the differentiation, the lower the grade
and less its invasiveness and thus the better
the prognosis
• GRADES 1 to 5
21. STAGING
• DUKES CLASSIFICATION
.A ; confined to the bowel wall
.B ; through bowel wall but not involving free
peritoneal serosal surface
.C ; lymph nodes are involved
22. STAGING contd
• ASTLER-COLLER (MODIFIED DUKES) CLASSIFICATION
.A ;Confined to mucosa
.B1 ;extends to but does not penetrate muscularis
mucosae
.B2 ;penetrates muscularis mucosae but no lymph node
involvement
.C1 ;limited to the bowel but with paracolic lymph node
involvement
.C2 ;growth has spread to lymph nodes at the highest
point of ligature
.D ;there is distant metastasis
28. SYMPTOMS
• Change in bowel habit
• Abdominal pain
• Spurious diarrhoea
• Change in calibre of stools
• Bleeding per rectum(haematochezia, mixed with
feces)
• Mucus in feces
• Borborygmi ,distension
• Dyspepsia from gastrocolic reflex in ca caecum
29. • Abdominal mass; RIF or epigastrum
• Symptoms of anaemia
• Constitutional symptoms of cancer
• Haemorrhoids
• Symptoms of local spread
• Symptoms of metastasis
• One third of patients present as an emergency
30. DIFFERENTIAL DIAGNOSIS
BASED ON LOCATION OF THE TUMOUR
• CAECAL CARCINOMA
.Amoebiasis
.Tuberculosis
.Actinomycosis
.Appendix mass/ abscess
.schistosomiasis
.Ovarian cyst
.Pedunculated fibroid
.Crohns dx, terminal ileitis
31. • TRANSVERSE COLON
.Gastric tumour
.Pseudocyst of the pancreas
.Renal swellings
.Splenic swellings
.Ca gall bladder
34. INVESTIGATIONS
• GENERAL INVESTIGATIONS TO PREPARE PX FOR
SURGERY OR OTHER TREATMENT MODALITIES
.Urinalysis
.FBC
.E/u/Cr
.CXR, ECG as indicated
.Group and crossmatch blood
.Stool microscopy
.CEA
38. • INVESTIGATIONS TO DETERMINE EXTENT OF
SPREAD OF THE DISEASE
.Endorectal ultrasound scan
.CXR
.Abdominopelvic Uss
.Intraoperative liver USS
.CT scan
.MRI
39. TREATMENT
• GENERAL SUPPORTIVE MEASURES
.Bowel preparation; diet, whole gut irrigation,
rectal enema/ washout, antibiotics, PEG
.Correction of anaemia
.Improve nutrition
.Prophylactic antibiotics
.DVT prophlaxis
.Anti amoebic therapy
.Planning of colostomy
40. DEFINITIVE TREATMENT
• Depends on location of the tumour, extent of
the tumour and the area of bowel spplied by
the main feeding vessel
• Caecal or right sided tumours; RIGHT
HEMICOLECTOMY
• Transverse colon tuours; TRANSVERSE
COLECTOMY
• Left sided tumours; LEFT HEMICOLECTOMY
• Sigmoid tumours; SIGMOID COLECTOMY
41.
42.
43.
44. RECTAL CA
• Preoperative radiotherapy
• Tumour > 10cm from anal verge( ANTERIOR
RESECTION OF THE RECTUM
• Tumour between 6-10 cm (LOW ANTERIOR
RESECTION)
• Tumour < 6cm from anal verge(
ABDOMINOPERINEAL RESECTION WITH
PERMANENT COLOSTOMY)
• Local excision for T1 tumours
47. ADJUVANT THERAPY
• Chemotherapy , 5FU, capecitabine, oxaliplatin
and irinotecan, leucovorin
• Regimens include FOLFOX and FOLFIRI
• Targeted therapy eg BEVACIZUMAB and
CETUXIMAB which are monoclonal antibodies
against vascular endothelial growth factor and
epidermal growth factor respectively