Presented by: Nicolas Rodondi, MD, MAS, Reto Auer, MD, Patrick J. Devine, MD, Patrick G. O’Malley, MD, MPH, Daniel Hayoz, MD, Jacques Cornuz, MD, MPH

1. The Impact of Carotid Plaque Screening on Motivation for Smoking Cessation and Knowledge Retention About Atherosclerosis Nicolas Rodondi, MD, MAS, Reto Auer, MD, Patrick J. Devine, MD, Patrick G. O’Malley, MD, MPH, Daniel Hayoz, MD, Jacques Cornuz, MD, MPH Consultation de Prévention Cardiovasculaire & Consultation des Lipides Policlinique Médicale Universitaire Université de Lausanne

10. Pilot Study: Participant Characteristics (n=30) Variable Mean (± SD) or % Mean age [range], yr 51.7 ± 9.4 [40 – 70] Women 43.3 % Daily cigarette consumption 22.2 ± 9 Pack-year smoking history 38.3 ± 19.3 Previous attempts of smoking cessation 83.3 % By attempters (n=25), number of previous attempts of smoking cessation 3.1 ± 2.2 [1-10] Fagerström score 4.8 ± 2.3

11. Smoking cessation at two months Motivation for smoking cessation, 1-10 Pre-screening 72.7% 37.5% Smoking cessation at 2 months, % 7.9 No plaque Plaque No plaque (n=8) Plaque (n=22) Pre-screening At 2 months At 2 months P = 0.10 P = 1.0 P = 0.008 7.2 8.7 At 2 months At 2 months N Rodondi et al, Nicotine & Tobacco Research 2008

12. Baseline At two months P Stress Perceived 4-Item stress scale, 2.0 [0-5] 1.5 [0-3.5] 0.13 range 0-16 Group without carotid plaques 1.0 [0-2.5] 2 [0-3.5] 0.66 Group with carotid plaques 2.5 [1-5.5] 0.5 [0-3.5] 0.04 Anxiety , range 0-14, Prime-MD 4.0 [0-7.5] 2.0 [0-4.0] 0.01 Group without range carotid plaques 4.0 [2.0-5.5] 1.5 [0.5-4.0] 0.11 Group with carotid plaques 3.5 [0-8.0] 2.0 [0-4.0] 0.04 Depression , range 0-27, Prime-MD 4.0 [2.0-6.5] 3.0 [0.5-4.5] 0.02 Group without range carotid plaques 6.0 [4.0-7.5] 3.5 [0.5-5.0] 0.08 Group with carotid plaques 4.0 [2.0-6.0] 3.0 [1.0-4.5] 0.12 Potential harms of screening Range 1-10, median [25%-75%] N Rodondi et al, Nicotine & Tobacco Research 2008

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