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Dr. Mohamed Alshekhani
Professor in Medicine
MBChB-CABM-FRCP-EBGH
2015
1
CME:1
• 1. Acute lower GI Bleeding constitutes what % of all acute GIB:
• A. 10%.
• B. 20%.
• C. 30%.
• D. 40%.
• E. 50%.
CME:2
• 2. What % of presumed acute lower GI Bleeding are found to have
upper GI source:
• A. 10%.
• B. 15%.
• C. 20%.
• D. 30%.
• E. 50%.
CME:3
• 3. What % of acute GI bleeding is due to small intestinal source:
• A. 1%.
• B. 5%.
• C. 10%.
• D. 15%.
• E. 20%.
CME:4
• 4. Bleeding from which colonic areas can present with melena
rather than hematochesia:
• A. Cecum.
• B. Transverse colon.
• C. Descending colon.
• D. Rectum.
• E. Splenic flexture.
CME:5
• 5. What % of melena could be from the colon:
• A. 10%.
• B. 20%.
• C. 30%.
• D. 40%.
• E. 50%.
CME:6
• 6. In acute lower GIB & hemodynamic instability, an upper GIT
source is best explored by:
• A. upper GI endoscopy.
• B. NT tube.
• C. Capsule endoscopy.
• D. RBC scan.
• E. CT Angio.
CME:7
• 7. The following should be the goal in patients with acute lower GIB
before enedoscopic evaluation except:
• A. Normal BP.
• B. Normal heart rate.
• C. Hb > 7 gms in low risk patients.
• D. Hb > 9 gram in high risk patients.
• E. Hb > 9 grams in all patients.
CME:8
• 8. In acute LGIB endoscopic hemostasis can be done safely without
the use of reversal agents , with INR up to:
• A. 3.
• B. 4.
• C. 2.5.
• D. 5.
• E. 6.
CME:9
• 9. In patients with acute LGIB, endoscopic intervention can be
carried out safely with platelet counts:
• A. 50000.
• B. 10000.
• C. 20000.
• D. 30000.
• E. 5000.
CME:10
• 10. Colonic preparation in acute LGI bleeding should be
adminstered over:
• A. One hour.
• B. Two hours.
• C. Three hours.
• D. Five hours.
• E. Six hours.
CME:11
• 11. In patients with ongoing acute LGI bleeding, colonoscopy should
be performed after stabilization & adequate preparation within:
• 6 hours.
• B. 12 hours.
• C. 24 hours.
• D. 36 hours.
• E. 48 hours.
CME:12
• 12. In patients with acute LGI bleeding but not ongoing,
colonoscopy should performed after stabilization & adequate
preparation within:
• 6 hours.
• B. 12 hours.
• C. When next available.
• D. 36 hours.
• E. 48 hours.
CME:13
• 13. Endoscopic interventions indications for acute LGI bleeding compared to
acute UGI bleeding is:
• A. The same.
• B. Different.
• C. Only done for spurting vessels.
• D. Done done for adherent clot.
• E. Contact thermal modalities are preferred.
CME:14
• 14. The preferred endoscopic intervention indicated for acute LGI
bleeding due to diverticulosis is:
• A. Clips.
• B. Bands.
• C. Thermal.
• D. APC.
• E. Saline injection only.
CME:15
• 15. The preferred endoscopic intervention indicated for acute LGI
bleeding due to angiodysplasia is:
• A. Clips.
• B. Bands.
• C. Thermal.
• D. APC.
• E. Saline injection only.
CME:16
• 16. The preferred endoscopic intervention indicated for acute LGI
bleeding post-polypectomy is:
• A. Clips.
• B. Bands.
• C. Thermal.
• D. APC.
• E. Saline injection only.
CME:17
• 17. The preferred endoscopic intervention indicated for acute LGI
bleeding from post-polypectomy if through the scope clips are not
available is:
• A. Over the scope clips.
• B. Bands.
• C. Thermal contact therapy.
• D. APC.
• E. Saline injection only.
CME:18
• 18. Before surgery is considered for acute LGI Bleeding , the most
important point is:
• A. Localize the bleeding site.
• B. Risk stratification.
• C. Anesthesia tolerance.
• D. Good history taking.
• E. Hb level.
CME:19
• 19. The diagnostic modality to localize the bleeding site in acute LGI
Bleeding before angiography is:
• A. CT Angio.
• B. RBC scan.
• C. MRI Angio.
• D. CT Colonography.
• E. Barium enema.
CME:20
• 20. Radiographic intervention is indicated for acute LGI bleeding
with all the following characteristics except:
• A. Ongoing bleeding.
• B. High risk patient.
• C. Preparation intolerants.
• D. Colonoscopy intolerants.
• E. All massive bleeders.
CME:21
• 21. In the majority of patients with acute LGI bleeding the initial
diagnostic modality is:
• A. Colonoscopy.
• B. CT Angio.
• C. Angiograpy.
• D. Barium enema.
• E. CT colonography.
Introduction:
• Acute overt LGIB accounts for ~20% of all cases of GIB.
• Usually leads to hospital admission with invasive diagnostic
evaluations& consumes significant medical resources.
• Most patients with ALGIB stop bleeding spontaneously with
favorable outcomes, morbidity / mortality are increased in older
patients & those with comorbid medical conditions.
• ALGIB classically presents with the sudden onset of hematochezia
(maroon or red blood passed per rectum).
• In rare cases, patients with bleeding from the cecum/right colon can
present with melena (black, tarry stools)
• Hematochezia can be seen in patients with brisk UGIB.
• 15% with ALGIB are ultimately found to have an UGI source.
• LGIB: from the colon or the rectum, SIB (middle GIB) is distinct from
colonic bleeding in terms of presentation, management &
outcomes.
Conclusion:
• Hemodynamic status should be initially assessed with intravascular
volume resuscitation started as needed.
• Risk stratification based on clinical parameters should be performed
to help distinguish patients at high&low-risk of adverse outcomes.
• Hematochezia associated with hemodynamic instability may be
indicative of UGI bleeding source &warrants an upper endoscopy.
• In the majority of patients,colonoscopy should be the initial
diagnostic procedure performed within 24 h of patient presentation
after adequate colon preparation.
• Endoscopic hemostasis therapy should be provided to patients with
high-risk endoscopic stigmata of bleeding including active bleeding,
non-bleeding visible vessel, or adherent clot.
• The endoscopic hemostasis modality used (mechanical, thermal,
injection, or combination) is most often guided by the etiology of
bleeding, access to the bleeding site&endoscopist experience.
Conclusion:
• Repeat colonoscopy, with endoscopic hemostasis performed if
indicated, should be considered for evidence of recurrent bleeding.
• Radiographic interventions (tagged RBC scintigraphy, CT
angio&angiography) should be considered in high-risk patients with
ongoing bleeding who do not respond adequately to resuscitation &
who are unlikely to tolerate bowel preparation&colonoscopy.
• Strategies to prevent recurrent bleeding should be considered:
NSAIDs use should be avoided in patients with a history of ALGIB,
particularly if secondary to diverticulosis or angioectasia.
• Patients with established CVD who require aspirin (2ndary
prophylaxis) should resume aspirin ASAP after bleeding ceases at
least within 7 days, exact timing depends on bleeding severity,
perceived adequacy of hemostasis& risk of a thromboembolism.
• Surgery for prevention of recurrent LGIB should be individualized&
source of bleeding should be carefully localized before resection.
CME:1
• 1. Acute lower GI Bleeding constitutes what % of all acute GIB:
• A. 10%.
• B. 20%.
• C. 30%.
• D. 40%.
• E. 50%.
CME:2
• 2. What % of presumed acute lower GI Bleeding are found to have
upper GI source:
• A. 10%.
• B. 15%.
• C. 20%.
• D. 30%.
• E. 50%.
CME:3
• 3. What % of acute GI bleeding is due to small intestinal source:
• A. 1%.
• B. 5%.
• C. 10%.
• D. 15%.
• E. 20%.
CME:4
• 4. Bleeding from which colonic areas can present with melena
rather than hematochesia:
• A. Cecum.
• B. Transverse colon.
• C. Descending colon.
• D. Rectum.
• E. Splenic flexture.
CME:5
• 5. What % of melena could be from the colon:
• A. 10%.
• B. 20%.
• C. 30%.
• D. 40%.
• E. 50%.
CME:6
• 6. In acute lower GIB & hemodynamic instability, an upper GIT
source is best explored by:
• A. upper GI endoscopy.
• B. NT tube.
• C. Capsule endoscopy.
• D. RBC scan.
• E. CT Angio.
CME:7
• 7. The following should be the goal in patients with acute lower GIB
before enedoscopic evaluation except:
• A. Normal BP.
• B. Normal heart rate.
• C. Hb > 7 gms in low risk patients.
• D. Hb > 9 gram in high risk patients.
• E. Hb > 9 grams in all patients.
CME:8
• 8. In acute LGIB endoscopic hemostasis can be done safely without
the use of reversal agents , with INR up to:
• A. 3.
• B. 4.
• C. 2.5.
• D. 5.
• E. 6.
CME:9
• 9. In patients with acute LGIB, endoscopic intervention can be
carried out safely with platelet counts:
• A. 50000.
• B. 10000.
• C. 20000.
• D. 30000.
• E. 5000.
CME:10
• 10. Colonic preparation in acute LGI bleeding should be
adminstered over:
• A. One hour.
• B. Two hours.
• C. Three hours.
• D. Five hours.
• E. Six hours.
CME:11
• 11. In patients with ongoing acute LGI bleeding, colonoscopy should
be performed after stabilization & adequate preparation within:
• 6 hours.
• B. 12 hours.
• C. 24 hours.
• D. 36 hours.
• E. 48 hours.
CME:12
• 12. In patients with acute LGI bleeding but not ongoing,
colonoscopy should performed after stabilization & adequate
preparation within:
• 6 hours.
• B. 12 hours.
• C. When next available.
• D. 36 hours.
• E. 48 hours.
CME:13
• 13. Endoscopic interventions indications for acute LGI bleeding compared to
acute UGI bleeding is:
• A. The same.
• B. Different.
• C. Only done for spurting vessels.
• D. Done done for adherent clot.
• E. Contact thermal modalities are preferred.
CME:14
• 14. The preferred endoscopic intervention indicated for acute LGI
bleeding due to diverticulosis is:
• A. Clips.
• B. Bands.
• C. Thermal.
• D. APC.
• E. Saline injection only.
CME:15
• 15. The preferred endoscopic intervention indicated for acute LGI
bleeding due to angiodysplasia is:
• A. Clips.
• B. Bands.
• C. Thermal.
• D. APC.
• E. Saline injection only.
CME:16
• 16. The preferred endoscopic intervention indicated for acute LGI
bleeding post-polypectomy is:
• A. Clips.
• B. Bands.
• C. Thermal.
• D. APC.
• E. Saline injection only.
CME:17
• 17. The preferred endoscopic intervention indicated for acute LGI
bleeding from post-polypectomy if through the scope clips are not
available is:
• A. Over the scope clips.
• B. Bands.
• C. Thermal contact therapy.
• D. APC.
• E. Saline injection only.
CME:18
• 18. Before surgery is considered for acute LGI Bleeding , the most
important point is:
• A. Localize the bleeding site.
• B. Risk stratification.
• C. Anesthesia tolerance.
• D. Good history taking.
• E. Hb level.
CME:19
• 19. The diagnostic modality to localize the bleeding site in acute LGI
Bleeding before angiography is:
• A. CT Angio.
• B. RBC scan.
• C. MRI Angio.
• D. CT Colonography.
• E. Barium enema.
CME:20
• 20. Radiographic intervention is indicated for acute LGI bleeding
with all the following characteristics except:
• A. Ongoing bleeding.
• B. High risk patient.
• C. Preparation intolerants.
• D. Colonoscopy intolerants.
• E. All massive bleeders.
CME:21
• 21. In the majority of patients with acute LGI bleeding the initial
diagnostic modality is:
• A. Colonoscopy.
• B. CT Angio.
• C. Angiograpy.
• D. Barium enema.
• E. CT colonography.

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Git j club LGIB guides16.

  • 1. Dr. Mohamed Alshekhani Professor in Medicine MBChB-CABM-FRCP-EBGH 2015 1
  • 2. CME:1 • 1. Acute lower GI Bleeding constitutes what % of all acute GIB: • A. 10%. • B. 20%. • C. 30%. • D. 40%. • E. 50%.
  • 3. CME:2 • 2. What % of presumed acute lower GI Bleeding are found to have upper GI source: • A. 10%. • B. 15%. • C. 20%. • D. 30%. • E. 50%.
  • 4. CME:3 • 3. What % of acute GI bleeding is due to small intestinal source: • A. 1%. • B. 5%. • C. 10%. • D. 15%. • E. 20%.
  • 5. CME:4 • 4. Bleeding from which colonic areas can present with melena rather than hematochesia: • A. Cecum. • B. Transverse colon. • C. Descending colon. • D. Rectum. • E. Splenic flexture.
  • 6. CME:5 • 5. What % of melena could be from the colon: • A. 10%. • B. 20%. • C. 30%. • D. 40%. • E. 50%.
  • 7. CME:6 • 6. In acute lower GIB & hemodynamic instability, an upper GIT source is best explored by: • A. upper GI endoscopy. • B. NT tube. • C. Capsule endoscopy. • D. RBC scan. • E. CT Angio.
  • 8. CME:7 • 7. The following should be the goal in patients with acute lower GIB before enedoscopic evaluation except: • A. Normal BP. • B. Normal heart rate. • C. Hb > 7 gms in low risk patients. • D. Hb > 9 gram in high risk patients. • E. Hb > 9 grams in all patients.
  • 9. CME:8 • 8. In acute LGIB endoscopic hemostasis can be done safely without the use of reversal agents , with INR up to: • A. 3. • B. 4. • C. 2.5. • D. 5. • E. 6.
  • 10. CME:9 • 9. In patients with acute LGIB, endoscopic intervention can be carried out safely with platelet counts: • A. 50000. • B. 10000. • C. 20000. • D. 30000. • E. 5000.
  • 11. CME:10 • 10. Colonic preparation in acute LGI bleeding should be adminstered over: • A. One hour. • B. Two hours. • C. Three hours. • D. Five hours. • E. Six hours.
  • 12. CME:11 • 11. In patients with ongoing acute LGI bleeding, colonoscopy should be performed after stabilization & adequate preparation within: • 6 hours. • B. 12 hours. • C. 24 hours. • D. 36 hours. • E. 48 hours.
  • 13. CME:12 • 12. In patients with acute LGI bleeding but not ongoing, colonoscopy should performed after stabilization & adequate preparation within: • 6 hours. • B. 12 hours. • C. When next available. • D. 36 hours. • E. 48 hours.
  • 14. CME:13 • 13. Endoscopic interventions indications for acute LGI bleeding compared to acute UGI bleeding is: • A. The same. • B. Different. • C. Only done for spurting vessels. • D. Done done for adherent clot. • E. Contact thermal modalities are preferred.
  • 15. CME:14 • 14. The preferred endoscopic intervention indicated for acute LGI bleeding due to diverticulosis is: • A. Clips. • B. Bands. • C. Thermal. • D. APC. • E. Saline injection only.
  • 16. CME:15 • 15. The preferred endoscopic intervention indicated for acute LGI bleeding due to angiodysplasia is: • A. Clips. • B. Bands. • C. Thermal. • D. APC. • E. Saline injection only.
  • 17. CME:16 • 16. The preferred endoscopic intervention indicated for acute LGI bleeding post-polypectomy is: • A. Clips. • B. Bands. • C. Thermal. • D. APC. • E. Saline injection only.
  • 18. CME:17 • 17. The preferred endoscopic intervention indicated for acute LGI bleeding from post-polypectomy if through the scope clips are not available is: • A. Over the scope clips. • B. Bands. • C. Thermal contact therapy. • D. APC. • E. Saline injection only.
  • 19. CME:18 • 18. Before surgery is considered for acute LGI Bleeding , the most important point is: • A. Localize the bleeding site. • B. Risk stratification. • C. Anesthesia tolerance. • D. Good history taking. • E. Hb level.
  • 20. CME:19 • 19. The diagnostic modality to localize the bleeding site in acute LGI Bleeding before angiography is: • A. CT Angio. • B. RBC scan. • C. MRI Angio. • D. CT Colonography. • E. Barium enema.
  • 21. CME:20 • 20. Radiographic intervention is indicated for acute LGI bleeding with all the following characteristics except: • A. Ongoing bleeding. • B. High risk patient. • C. Preparation intolerants. • D. Colonoscopy intolerants. • E. All massive bleeders.
  • 22. CME:21 • 21. In the majority of patients with acute LGI bleeding the initial diagnostic modality is: • A. Colonoscopy. • B. CT Angio. • C. Angiograpy. • D. Barium enema. • E. CT colonography.
  • 23. Introduction: • Acute overt LGIB accounts for ~20% of all cases of GIB. • Usually leads to hospital admission with invasive diagnostic evaluations& consumes significant medical resources. • Most patients with ALGIB stop bleeding spontaneously with favorable outcomes, morbidity / mortality are increased in older patients & those with comorbid medical conditions. • ALGIB classically presents with the sudden onset of hematochezia (maroon or red blood passed per rectum). • In rare cases, patients with bleeding from the cecum/right colon can present with melena (black, tarry stools) • Hematochezia can be seen in patients with brisk UGIB. • 15% with ALGIB are ultimately found to have an UGI source. • LGIB: from the colon or the rectum, SIB (middle GIB) is distinct from colonic bleeding in terms of presentation, management & outcomes.
  • 24.
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  • 39. Conclusion: • Hemodynamic status should be initially assessed with intravascular volume resuscitation started as needed. • Risk stratification based on clinical parameters should be performed to help distinguish patients at high&low-risk of adverse outcomes. • Hematochezia associated with hemodynamic instability may be indicative of UGI bleeding source &warrants an upper endoscopy. • In the majority of patients,colonoscopy should be the initial diagnostic procedure performed within 24 h of patient presentation after adequate colon preparation. • Endoscopic hemostasis therapy should be provided to patients with high-risk endoscopic stigmata of bleeding including active bleeding, non-bleeding visible vessel, or adherent clot. • The endoscopic hemostasis modality used (mechanical, thermal, injection, or combination) is most often guided by the etiology of bleeding, access to the bleeding site&endoscopist experience.
  • 40. Conclusion: • Repeat colonoscopy, with endoscopic hemostasis performed if indicated, should be considered for evidence of recurrent bleeding. • Radiographic interventions (tagged RBC scintigraphy, CT angio&angiography) should be considered in high-risk patients with ongoing bleeding who do not respond adequately to resuscitation & who are unlikely to tolerate bowel preparation&colonoscopy. • Strategies to prevent recurrent bleeding should be considered: NSAIDs use should be avoided in patients with a history of ALGIB, particularly if secondary to diverticulosis or angioectasia. • Patients with established CVD who require aspirin (2ndary prophylaxis) should resume aspirin ASAP after bleeding ceases at least within 7 days, exact timing depends on bleeding severity, perceived adequacy of hemostasis& risk of a thromboembolism. • Surgery for prevention of recurrent LGIB should be individualized& source of bleeding should be carefully localized before resection.
  • 41. CME:1 • 1. Acute lower GI Bleeding constitutes what % of all acute GIB: • A. 10%. • B. 20%. • C. 30%. • D. 40%. • E. 50%.
  • 42. CME:2 • 2. What % of presumed acute lower GI Bleeding are found to have upper GI source: • A. 10%. • B. 15%. • C. 20%. • D. 30%. • E. 50%.
  • 43. CME:3 • 3. What % of acute GI bleeding is due to small intestinal source: • A. 1%. • B. 5%. • C. 10%. • D. 15%. • E. 20%.
  • 44. CME:4 • 4. Bleeding from which colonic areas can present with melena rather than hematochesia: • A. Cecum. • B. Transverse colon. • C. Descending colon. • D. Rectum. • E. Splenic flexture.
  • 45. CME:5 • 5. What % of melena could be from the colon: • A. 10%. • B. 20%. • C. 30%. • D. 40%. • E. 50%.
  • 46. CME:6 • 6. In acute lower GIB & hemodynamic instability, an upper GIT source is best explored by: • A. upper GI endoscopy. • B. NT tube. • C. Capsule endoscopy. • D. RBC scan. • E. CT Angio.
  • 47. CME:7 • 7. The following should be the goal in patients with acute lower GIB before enedoscopic evaluation except: • A. Normal BP. • B. Normal heart rate. • C. Hb > 7 gms in low risk patients. • D. Hb > 9 gram in high risk patients. • E. Hb > 9 grams in all patients.
  • 48. CME:8 • 8. In acute LGIB endoscopic hemostasis can be done safely without the use of reversal agents , with INR up to: • A. 3. • B. 4. • C. 2.5. • D. 5. • E. 6.
  • 49. CME:9 • 9. In patients with acute LGIB, endoscopic intervention can be carried out safely with platelet counts: • A. 50000. • B. 10000. • C. 20000. • D. 30000. • E. 5000.
  • 50. CME:10 • 10. Colonic preparation in acute LGI bleeding should be adminstered over: • A. One hour. • B. Two hours. • C. Three hours. • D. Five hours. • E. Six hours.
  • 51. CME:11 • 11. In patients with ongoing acute LGI bleeding, colonoscopy should be performed after stabilization & adequate preparation within: • 6 hours. • B. 12 hours. • C. 24 hours. • D. 36 hours. • E. 48 hours.
  • 52. CME:12 • 12. In patients with acute LGI bleeding but not ongoing, colonoscopy should performed after stabilization & adequate preparation within: • 6 hours. • B. 12 hours. • C. When next available. • D. 36 hours. • E. 48 hours.
  • 53. CME:13 • 13. Endoscopic interventions indications for acute LGI bleeding compared to acute UGI bleeding is: • A. The same. • B. Different. • C. Only done for spurting vessels. • D. Done done for adherent clot. • E. Contact thermal modalities are preferred.
  • 54. CME:14 • 14. The preferred endoscopic intervention indicated for acute LGI bleeding due to diverticulosis is: • A. Clips. • B. Bands. • C. Thermal. • D. APC. • E. Saline injection only.
  • 55. CME:15 • 15. The preferred endoscopic intervention indicated for acute LGI bleeding due to angiodysplasia is: • A. Clips. • B. Bands. • C. Thermal. • D. APC. • E. Saline injection only.
  • 56. CME:16 • 16. The preferred endoscopic intervention indicated for acute LGI bleeding post-polypectomy is: • A. Clips. • B. Bands. • C. Thermal. • D. APC. • E. Saline injection only.
  • 57. CME:17 • 17. The preferred endoscopic intervention indicated for acute LGI bleeding from post-polypectomy if through the scope clips are not available is: • A. Over the scope clips. • B. Bands. • C. Thermal contact therapy. • D. APC. • E. Saline injection only.
  • 58. CME:18 • 18. Before surgery is considered for acute LGI Bleeding , the most important point is: • A. Localize the bleeding site. • B. Risk stratification. • C. Anesthesia tolerance. • D. Good history taking. • E. Hb level.
  • 59. CME:19 • 19. The diagnostic modality to localize the bleeding site in acute LGI Bleeding before angiography is: • A. CT Angio. • B. RBC scan. • C. MRI Angio. • D. CT Colonography. • E. Barium enema.
  • 60. CME:20 • 20. Radiographic intervention is indicated for acute LGI bleeding with all the following characteristics except: • A. Ongoing bleeding. • B. High risk patient. • C. Preparation intolerants. • D. Colonoscopy intolerants. • E. All massive bleeders.
  • 61. CME:21 • 21. In the majority of patients with acute LGI bleeding the initial diagnostic modality is: • A. Colonoscopy. • B. CT Angio. • C. Angiograpy. • D. Barium enema. • E. CT colonography.