5. Diagnosis
• Determine the CC
• Take an accurate
medical history
• Complete a
thorough exam,
with all necessary
tests
• Perform a
radiographic exam
• Analyze and
synthesize results
• Establish a
treatment plan
17. Etiology
• After listening to the patient,
begin to determine the
etiology of the chief
complaint:
• Contents of the root canal?
• Dentist controlled factors?
• Host factors?
18. Contents of the
Root Canal
• Pulp tissue
• Bacteria
• Bacterial by-products
• Endodontic therapy materials
20. Hyperocclusion
• Rosenberg PA, Babick PJ,
Schertzer L, Leung A. The effect
of occlusal reduction on pain after
endodontic instrumentation. J
Endodon 1998;24:492.
21. Hyperocclusion
• Researchers have
found that patients
most likely to benefit
from occlusal
reduction are those
whose teeth initially
present with
symptoms.
• Indiscriminant
reduction of the
occlusal surface is
not indicated
• PRE-OP PAIN
• PULP VITALITY
• PERCUSSION
SENSITIVITY
• ABSENCE OF A
PERIRADICULAR
RADIOLUCENCY
• COMBINATION OF
THESE SYMPTOMS
27. Host Defense is Multi-
factorial
C E L L S
n e u tro p h ils , lym p h o c yte s ,
p la s m a c e lls , m a c ro p h a g e s ,
o s te o c la s ts , e p ith e lia l c e lls , d e n d ritic c e lls
M O L E C U L A R M E D IA T O R S
c yto k in e s (IL , IF N , C S F , T G F )
e ic o s a n o id s (P G , L T )
e n z ym a tic e ffe c to r m o le c u le s
A N T IB O D IE S
im m u n o g lo b u lin s (Ig G , e tc .)
p ro d u c e d b y p la s m a c e lls
M ixe d M ic ro flo ra
44. • Pre - op / loading dose
• Long acting anesthesia
• Prescription
Drugs
45. Codeine
• Prototype opioid for orally available
combination drugs
• Studies found that 60 mg of codeine
(2 T-3) produces significantly more
analgesia than placebo but less
analgesia than 650 mg aspirin, or
600 mg acetaminophen
47. • 57 patients
• Local anesthesia,
pulpectomy, post- op
analgesic
• Placebo
• 600 mg ibuprofen
• 600 mg ibuprofen & 1000 mg
acetaminophen
Ibuprofen and
Acetaminophen
48. • Visual analogue scale &
baseline 4-point category pain
scale
• 1 hr, 4 hr, 6 hr, 8 hr
• General linear model analyses
• Significant differences
• Placebo and combination
• Ibuprofen and combination
• No significant difference
• Placebo and ibuprofen
Ibuprofen and
Acetaminophen*
49. “The results demonstrate
that the combination of
ibuprofen and
acetaminophen may be
more effective than
ibuprofen alone for the
management of
postoperative endodontic
pain.”
Ibuprofen and
Acetaminophen*
51. Flexible Analgesic Plan
M I L D
2 0 0 - 4 0 0 m g ib u p r o fe n
o r 6 5 0 m g a s p ir in
M O D E R A T E
6 0 0 - 8 0 0 m g ib u p r o fe n
p lu s c o m b o a n a lg e s ic =
6 0 m g c o d e in e
S E V E R E
6 0 0 - 8 0 0 m g ib u p r o fe n
p lu s c o m b o a n a lg e s ic =
1 0 m g o x y c o d o n e
A s p ir in - lik e D r u g s a r e I n d ic a t e d
52. Flexible Analgesic Plan
M IL D
6 0 0 -1 0 0 0 a c e ta m in o p h e n
M O D E R A T E
6 0 0 -1 0 0 0 m g a c e ta m in o p h e n
a n d o p ia te =
6 0 m g c o d e in e
S E V E R E
1 0 0 0 m g a c e ta m in o p h e n
a n d o p ia te =
1 0 m g o x y c o d o n e
A s p irin -lik e D ru g s a re C o n tra in d ic a te d
53. Selected NSAID Drug
Interactions
Anticoagulants Increased prothrombin time or bleeding time
ACE Inhibitors Reduced antihypertensive effectiveness
Beta Blockers Reduced antihypertensive effects
Cyclosporine Increased risk of nephrotoxicity
Lithium Increased serum levels of lithium
Sympathomimetics Increased blood pressure
Thiazide Reduced antihypertensive effectiveness
54. • Systemic involvement
• Compromised host
resistance
• Fascial space involvement
• Inadequate surgical
drainage
Indications for
Antibiotic Therapy
55. Select antibiotic with
anaerobic spectrum
Use a larger dose for a
shorter period of time (“hard
and fast” rule)
Guidelines for
Antibiotic Therapy
56. • Gram stain results available:
antibiotic-sensitivity charts
• C & S results available:
antibiotic-sensitivity charts
• No gram stain or C & S results:
PCN is antibiotic of choice
Selecting the
Appropriate Antibiotic
57. Penicillin V
• Still, the drug of choice for
infections of endodontic origin
• Loading dose: 1-2 g then 500 mg qid
x 7-10 days
58. Metronidozole
(Flagyl)
• Used in conjunction with Penicillin
V
• 500 mg of Penicillin V with 250 mg
Metronidozole, qid x 7-10 days