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Intel Health & Life Sciences
Where information and care meet

Practical Cloud Adoption
for the Health & Life Sciences Industry

Chris Gough
Lead Solutions Architect, Intel Health & Life Sciences
Agenda
•
•
•
•
•

2

Healthcare Cloud Computing
Balanced Cloud Solutions
Case Studies
Improving UX With Hardware-Assisted Security
Additional Resources

Intel Health & Life Sciences
Where information and care meet
The Building Surge of Healthcare Data
• Digitization of healthcare data
• Higher resolution images, sound, video
• New data types; e.g. genomics

• Longer retention needs
• Health information exchange, and
proliferation of duplicates
• Sensitive data must be protected everywhere
• Access required anywhere, anytime on any device
Cloud can help address these challenges
Security, compliance and user experience are critical considerations
3

Intel Health & Life Sciences
Where information and care meet
Healthcare Cloud Computing
Business Drivers

Concerns

Cost Reduction: Economies of scale,
multi-tenancy

regulations

Agility: Elasticity, provisioning
Availability: Highly redundant, geodispersed

Leverage External Expertise

Security & Privacy: Data breach,
Data Sovereignty: Where is my data?
Auditability & Compliance:
Complicated by distributed cloud

Vendor Lock-In

How to maximize benefits and minimize concerns? One size does not fit all
4

Intel Health & Life Sciences
Where information and care meet
Where in the Spectrum Are Your Cloud Workloads?

5

Intel Health & Life Sciences
Where information and care meet
Intel Open Cloud Vision
IT Requirements & Open
Standards

Optimized Platforms

Intel® Cloud Builders &
Cloud Finder

Define and Prioritize
IT Requirements &
Accelerate Open Industry
Standards

Deliver optimized products
for more secure, efficient,
automated platforms built on
a common architecture

Enable proven solutions that
ease cloud adoption & help
guide cloud service provider
selection

Interoperable, Built on Open, Multi-Vendor Solutions & Industry Standards
6

Intel Health & Life Sciences
Where information and care meet
Service Orchestration for your Cloud Environment
Deep Engagement and Support for all major Cloud Operating Environment and
platform solutions
*

vCloud Director

Hyper-V

vSphere
NSX

vSAN
SSD

7

*

System Center 2012

vCenter Server

ESXi

*

Windows Server 2012

Hard
disks

Intel Health & Life Sciences
Where information and care meet

OpenStack APIs
Watcher
(Nagios*)

Decider
(internal)

Actor
(Puppet*)

Collector
(HDFS)

Dashboard (Horizon)
Compute (Nova)

Network
(Quantum)

Storage
(Cinder | Swift)
Intel Healthcare Cloud Computing
Intel Works with Customers, Partners, Alliances, and Standards Bodies to
Produce Scalable, Secure Cloud Solutions Based on Today’s
Health IT Requirements¹

Protect sensitive health
information in transit, at rest, and
in use with hardware-assisted
security²

Improve mission-critical
information availability with
reliability and serviceability
features

1. Intel® Cloud Builders
2. Hardware-assisted Security
For more… www.intel.com/healthcare/cloud and www.intelcloudfinder.com

8

Intel Health & Life Sciences
Where information and care meet

Control costs with balanced, “scaleout” solutions based on Intel®
compute, networking, and storage
capabilities
Balanced Cloud Solutions

9

Intel Health & Life Sciences
Where information and care meet
Cloud Technologies – The Power of the Platform
TeraSort for 1TB sort
~4 hour process time

UPGRADE TO INTEL®
XEON® PROCESSOR
E5-2600 V2

50 %

~

reduction

Intel® Xeon ® 5600
HDD 1GbE

Hadoop processing time
~10 minutes with Complete Intel-based solution
UPGRADE
TO SSD

80

UPGRADE
TO 10GBE

~

reduction

50

~

reduction

INTEL
DISTRIBUTION

40

~

reduction

http://www.intel.com/content/dam/www/public/us/en/documents/white-papers/10gbe-10gbase-t-hadoop-clusters-paper.pdf
Software and workloads used in performance tests may have been optimized for performance only on Intel microprocessors. Performance tests, such as SYSmark and MobileMark, are measured using specific computer systems, components, software, operations and functions. Any change to
any of those factors may cause the results to vary. You should consult other information and performance tests to assist you in fully evaluating your contemplated purchases, including the performance of that product when combined with other products.

10

Source: Intel internal measurement using a standard Hadoop benchmark, TeraSort, on a cluster of 10 top
bin Xeon 5600 based servers sort 1TB of data Westmere 3HDD + 1GbE = 250 minutes; Romley 3HDD
+1GbE = 125 Minutes; Romley 4SSD + 1GbE = 23 minutes; Romley 4SSD + 10GbE = 12 minutes; Romley
4SSD + 10GbE + Intel Hadoop Distribution = 7 minutes
Other names and brands may be claimed as the property of others

Intel Health & Life Sciences
Where information and care meet
Ultra High-Speed Networking Optimizations
Aspera Labs
• Challenge: Improving big data transfer to and from the backend
data center

• Solution: Optimize ultra high-speed (10 Gbps and beyond) data
transfer solutions built on Aspera’s FASP ™ transport technology
and Intel’s innovative hardware platform
• Benefits with Intel Xeon E5-2600 (DDIO, SR-IOV)
− 300% improvement in Aspera transfer throughput
− Same transfer speed performance in both physical and virtualized
computing environments
− Both LAN and WAN transfer speeds had similar results
• Infrastructure and Data Characteristics:
−
−

11

Xeon E5 2687, 32GB DDR3 with Non-Uniform Memory Access (NUMA) Data Direct IO (DDIO), Intel 910 SSD,
Intel 82599EB 10 GbE
Aspera Enterprise server 3.1.1.66573, Aspera Performance Automation Suite

Intel Health & Life Sciences
Where information and care meet
High Throughput Science: Embracing Cloud-based Analytics
• Challenge: Team of cancer researchers had to screen a
drug concept with a list of tens of millions of molecules
working with a tight deadline, a fixed budget, and strict
security and compliance requirements. Schrödinger’s
existing in-house servers would be tied up for weeks
• Solution: Schrödinger used software from AWS partner,
Cycle Computing, to provision a fully secured cluster of
50,000 cores, powered by the Intel® Xeon® processor
E5 family.
− This configuration enabled the team to run 16
million molecular simulations an hour.
− Developed 1000 molecule list in < 8hrs.

12

Intel Health & Life Sciences
Where information and care meet
GEHC Medical Quality Improvement Consortium
Challenge – How to gain added value from wealth
(MQIC)
of data in EMRs/EHRs and other digital health
information tools

Solution – Providers contribute de-identified data
from their Centricity EMRs and used the resulting
data warehouse and analytics capabilities to
enhance their quality and reporting activities.
1.6 billion documents representing 30 million deidentified patient records and 209 million office
visits.
Benefits - Physician practices and ambulatory care
clinics deliver their best care more efficiently,
along with population-based research and public
health activities.
13

Intel Health & Life Sciences
Where information and care meet
Enhancing Datacenter Workload Security
ISOLATE

ENFORCE

ENCRYPT

Intel® VT and
Intel® TXT

Intel® TXT

Intel® AES-NI

Establishes “trusted” status
foundation for security policybased workload control

Delivers built-in encryption
acceleration for better data
protection

Protects VM isolation and
provides a more secure
platform launch

Security Standards
Intel & partners are collaborating to drive unification and
consensus across industry security standards to enable
consistent controls and protections

14

Intel Health & Life Sciences
Where information and care meet

ANALYZE
Intel® Distribution
Apache Hadoop*

Hardware-enhanced analytics
platform to achieve insights
faster
Circumventing Security of Compromised Solutions
in the Way of Healthcare
•
•
•
•
•
•

15

Slow encryption
Vulnerable security
Unusable 2-factor authentication
Expensive security
Compromised healthcare solutions
Many [risky] alternatives!

Intel Health & Life Sciences
Where information and care meet
Past

• Security

Trend

Enabling Healthcare with More Usable and Secure
Safeguard Solutions

• Migrate

software on general hardware

• Separate

security hardware

core security logic to hardware

• Integrate

Security
Software

Security
Software

Core
Security
Logic

Core
Security
Logic
Trend

General
Purpose
Hardware

Core
Security
Logic

• Robust
Future

separate security hardware
• Performant, e.g., encryption

Separate
Security
Hardware

General
Purpose
Hardware

(hardened), e.g., advanced
behavior / heuristics anti-malware

• Usable,

e.g., manageable systems “just
work,” 2-factor authentication

• Cost
16

effective

Performance,
Robustness,
Usability, Cost
Time

Intel Health & Life Sciences
Where information and care meet

Better
Global Net Access Health (GNAX Health) is a leading healthcare technology infrastructure provider
Learn more at www.gnaxhealth.com

Key Challenges
• Launch New Cloud Services to meet growing demand from healthcare organizations for flexible, costeffective, outsourced IT
• Provide a Trusted Environment that helps providers protect sensitive information and comply with
regulations

Solution
• Infrastructure based on Intel® Xeon E5 servers
• Integrated Intel® AES-NI technology improved encryption performance by 49.25% (1.97x) and
improved decryption performance by 62.16% (2.64x)
• AES-NI hardened against side channel attacks and associated exploits
AES -NI is a set of instructions that consolidates mathematical operations used in the Advanced Encryption Standard (AES) algorithm. Enabling AES-NI requires a computer system with an AES-NI-enabled processor as well as non-Intel software to execute the instructions in the correct sequence.
For availability of AES-NI enabled processors or systems, check with your reseller or system manufacturer.

17

Intel Health & Life Sciences
Where information and care meet
Summary
• Healthcare is undergoing a rapid transformation

• Agile organizations will be best positioned to adapt
quickly to this changing environment

• Cloud computing can enable agile, cost effective, and highly
available solutions… but ensuring security and
compliance concerns are addressed is paramount
• Intel is working with fellow travelers to produce secure,
high performance, cloud solutions that help meet
compliance and integration needs of the healthcare
industry
18

Intel Health & Life Sciences
Where information and care meet
Additional Resources
chris.s.gough@intel.com
Secure Cloud for Healthcare Data
Atlantic Health System Harnesses Data Growth
CareAlign Exchange Secures Healthcare Data (ICA - AES-NI)
Intel TXT Enables a Trusted, High Performance Cloud (DuPont)
Building a Cloud For Healthcare (GNAX – AES-NI)
High Performance Encryption for EHR Databases
Big Data Technologies for Ultra-High-Speed Data Transfer & Processing
(Aspera/Intel)
• Cycle Computing – Utility HPC – Cloud Slam 2013
• GE Medical Quality Improvement Consortium (Private Cloud)
•
•
•
•
•
•
•
•

19

Intel Health & Life Sciences
Where information and care meet
Legal Information
Today’s presentations contain forward-looking statements. All statements made that are not historical facts are subject to a number of risks and uncertainties, and actual results may differ materially. Please refer to our
most recent Earnings Release and our most recent Form 10-Q or 10-K filing for more information on the risk factors that could cause actual results to differ.
If we use any non-GAAP financial measures during the presentations, you will find on our website, intc.com, the required reconciliation to the most directly comparable GAAP financial measure.
INFORMATION IN THIS DOCUMENT IS PROVIDED “AS IS”. NO LICENSE, EXPRESS OR IMPLIED, BY ESTOPPEL OR OTHERWISE, TO ANY INTELLECTUAL PROPERTY RIGHTS IS GRANTED BY THIS DOCUMENT. INTEL
ASSUMES NO LIABILITY WHATSOEVER AND INTEL DISCLAIMS ANY EXPRESS OR IMPLIED WARRANTY, RELATING TO THIS INFORMATION INCLUDING LIABILITY OR WARRANTIES RELATING TO FITNESS FOR A
PARTICULAR PURPOSE, MERCHANTABILITY, OR INFRINGEMENT OF ANY PATENT, COPYRIGHT OR OTHER INTELLECTUAL PROPERTY RIGHT.
Software and workloads used in performance tests may have been optimized for performance only on Intel microprocessors. Performance tests, such as SYSmark and MobileMark, are measured using specific computer
systems, components, software, operations and functions. Any change to any of those factors may cause the results to vary. You should consult other information and performance tests to assist you in fully evaluating
your contemplated purchases, including the performance of that product when combined with other products.
Intel product plans in this presentation do not constitute Intel plan of record product roadmaps. Please contact your Intel representative to obtain Intel's current plan of record product roadmaps.
Intel's compilers may or may not optimize to the same degree for non-Intel microprocessors for optimizations that are not unique to Intel microprocessors. These optimizations include SSE2, SSE3, and SSE3 instruction
sets and other optimizations. Intel does not guarantee the availability, functionality, or effectiveness of any optimization on microprocessors not manufactured by Intel.
Microprocessor-dependent optimizations in this product are intended for use with Intel microprocessors. Certain optimizations not specific to Intel microarchitecture are reserved for Intel microprocessors. Please refer to
the applicable product User and Reference Guides for more information regarding the specific instruction sets covered by this notice.
Notice revision #20110804
All products, computer systems, dates, and figures specified are preliminary based on current expectations, and are subject to change without notice.
Intel processor numbers are not a measure of performance. Processor numbers differentiate features within each processor family, not across different processor families. Go to:
http://www.intel.com/products/processor_number
Intel, processors, chipsets, and desktop boards may contain design defects or errors known as errata, which may cause the product to deviate from published specifications. Current characterized errata are available on
request.
Intel® Virtualization Technology requires a computer system with an enabled Intel® processor, BIOS, virtual machine monitor (VMM). Functionality, performance or other benefits will vary depending on hardware and
software configurations. Software applications may not be compatible with all operating systems. Consult your PC manufacturer. For more information, visit http://www.intel.com/go/virtualization
No computer system can provide absolute security under all conditions. Intel® Trusted Execution Technology (Intel® TXT) requires a computer system with Intel® Virtualization Technology, an Intel TXT-enabled
processor, chipset, BIOS, Authenticated Code Modules and an Intel TXT-compatible measured launched environment (MLE). Intel TXT also requires the system to contain a TPM v1.s. For more information, visit
http://www.intel.com/technology/security
Intel, Intel Xeon, Intel Atom, Intel Xeon Phi, Intel Itanium, the Intel Itanium logo, the Intel Xeon Phi logo, the Intel Xeon logo and the Intel logo are trademarks or registered trademarks of Intel Corporation or its
subsidiaries in the United States and other countries.
Other names and brands may be claimed as the property of others.
Copyright © 2013, Intel Corporation. All rights reserved.

20

Intel Health & Life Sciences
Where information and care meet
Thank You

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Practical cloud adoption for the health & life sciences industry

  • 1. Intel Health & Life Sciences Where information and care meet Practical Cloud Adoption for the Health & Life Sciences Industry Chris Gough Lead Solutions Architect, Intel Health & Life Sciences
  • 2. Agenda • • • • • 2 Healthcare Cloud Computing Balanced Cloud Solutions Case Studies Improving UX With Hardware-Assisted Security Additional Resources Intel Health & Life Sciences Where information and care meet
  • 3. The Building Surge of Healthcare Data • Digitization of healthcare data • Higher resolution images, sound, video • New data types; e.g. genomics • Longer retention needs • Health information exchange, and proliferation of duplicates • Sensitive data must be protected everywhere • Access required anywhere, anytime on any device Cloud can help address these challenges Security, compliance and user experience are critical considerations 3 Intel Health & Life Sciences Where information and care meet
  • 4. Healthcare Cloud Computing Business Drivers Concerns Cost Reduction: Economies of scale, multi-tenancy regulations Agility: Elasticity, provisioning Availability: Highly redundant, geodispersed Leverage External Expertise Security & Privacy: Data breach, Data Sovereignty: Where is my data? Auditability & Compliance: Complicated by distributed cloud Vendor Lock-In How to maximize benefits and minimize concerns? One size does not fit all 4 Intel Health & Life Sciences Where information and care meet
  • 5. Where in the Spectrum Are Your Cloud Workloads? 5 Intel Health & Life Sciences Where information and care meet
  • 6. Intel Open Cloud Vision IT Requirements & Open Standards Optimized Platforms Intel® Cloud Builders & Cloud Finder Define and Prioritize IT Requirements & Accelerate Open Industry Standards Deliver optimized products for more secure, efficient, automated platforms built on a common architecture Enable proven solutions that ease cloud adoption & help guide cloud service provider selection Interoperable, Built on Open, Multi-Vendor Solutions & Industry Standards 6 Intel Health & Life Sciences Where information and care meet
  • 7. Service Orchestration for your Cloud Environment Deep Engagement and Support for all major Cloud Operating Environment and platform solutions * vCloud Director Hyper-V vSphere NSX vSAN SSD 7 * System Center 2012 vCenter Server ESXi * Windows Server 2012 Hard disks Intel Health & Life Sciences Where information and care meet OpenStack APIs Watcher (Nagios*) Decider (internal) Actor (Puppet*) Collector (HDFS) Dashboard (Horizon) Compute (Nova) Network (Quantum) Storage (Cinder | Swift)
  • 8. Intel Healthcare Cloud Computing Intel Works with Customers, Partners, Alliances, and Standards Bodies to Produce Scalable, Secure Cloud Solutions Based on Today’s Health IT Requirements¹ Protect sensitive health information in transit, at rest, and in use with hardware-assisted security² Improve mission-critical information availability with reliability and serviceability features 1. Intel® Cloud Builders 2. Hardware-assisted Security For more… www.intel.com/healthcare/cloud and www.intelcloudfinder.com 8 Intel Health & Life Sciences Where information and care meet Control costs with balanced, “scaleout” solutions based on Intel® compute, networking, and storage capabilities
  • 9. Balanced Cloud Solutions 9 Intel Health & Life Sciences Where information and care meet
  • 10. Cloud Technologies – The Power of the Platform TeraSort for 1TB sort ~4 hour process time UPGRADE TO INTEL® XEON® PROCESSOR E5-2600 V2 50 % ~ reduction Intel® Xeon ® 5600 HDD 1GbE Hadoop processing time ~10 minutes with Complete Intel-based solution UPGRADE TO SSD 80 UPGRADE TO 10GBE ~ reduction 50 ~ reduction INTEL DISTRIBUTION 40 ~ reduction http://www.intel.com/content/dam/www/public/us/en/documents/white-papers/10gbe-10gbase-t-hadoop-clusters-paper.pdf Software and workloads used in performance tests may have been optimized for performance only on Intel microprocessors. Performance tests, such as SYSmark and MobileMark, are measured using specific computer systems, components, software, operations and functions. Any change to any of those factors may cause the results to vary. You should consult other information and performance tests to assist you in fully evaluating your contemplated purchases, including the performance of that product when combined with other products. 10 Source: Intel internal measurement using a standard Hadoop benchmark, TeraSort, on a cluster of 10 top bin Xeon 5600 based servers sort 1TB of data Westmere 3HDD + 1GbE = 250 minutes; Romley 3HDD +1GbE = 125 Minutes; Romley 4SSD + 1GbE = 23 minutes; Romley 4SSD + 10GbE = 12 minutes; Romley 4SSD + 10GbE + Intel Hadoop Distribution = 7 minutes Other names and brands may be claimed as the property of others Intel Health & Life Sciences Where information and care meet
  • 11. Ultra High-Speed Networking Optimizations Aspera Labs • Challenge: Improving big data transfer to and from the backend data center • Solution: Optimize ultra high-speed (10 Gbps and beyond) data transfer solutions built on Aspera’s FASP ™ transport technology and Intel’s innovative hardware platform • Benefits with Intel Xeon E5-2600 (DDIO, SR-IOV) − 300% improvement in Aspera transfer throughput − Same transfer speed performance in both physical and virtualized computing environments − Both LAN and WAN transfer speeds had similar results • Infrastructure and Data Characteristics: − − 11 Xeon E5 2687, 32GB DDR3 with Non-Uniform Memory Access (NUMA) Data Direct IO (DDIO), Intel 910 SSD, Intel 82599EB 10 GbE Aspera Enterprise server 3.1.1.66573, Aspera Performance Automation Suite Intel Health & Life Sciences Where information and care meet
  • 12. High Throughput Science: Embracing Cloud-based Analytics • Challenge: Team of cancer researchers had to screen a drug concept with a list of tens of millions of molecules working with a tight deadline, a fixed budget, and strict security and compliance requirements. Schrödinger’s existing in-house servers would be tied up for weeks • Solution: Schrödinger used software from AWS partner, Cycle Computing, to provision a fully secured cluster of 50,000 cores, powered by the Intel® Xeon® processor E5 family. − This configuration enabled the team to run 16 million molecular simulations an hour. − Developed 1000 molecule list in < 8hrs. 12 Intel Health & Life Sciences Where information and care meet
  • 13. GEHC Medical Quality Improvement Consortium Challenge – How to gain added value from wealth (MQIC) of data in EMRs/EHRs and other digital health information tools Solution – Providers contribute de-identified data from their Centricity EMRs and used the resulting data warehouse and analytics capabilities to enhance their quality and reporting activities. 1.6 billion documents representing 30 million deidentified patient records and 209 million office visits. Benefits - Physician practices and ambulatory care clinics deliver their best care more efficiently, along with population-based research and public health activities. 13 Intel Health & Life Sciences Where information and care meet
  • 14. Enhancing Datacenter Workload Security ISOLATE ENFORCE ENCRYPT Intel® VT and Intel® TXT Intel® TXT Intel® AES-NI Establishes “trusted” status foundation for security policybased workload control Delivers built-in encryption acceleration for better data protection Protects VM isolation and provides a more secure platform launch Security Standards Intel & partners are collaborating to drive unification and consensus across industry security standards to enable consistent controls and protections 14 Intel Health & Life Sciences Where information and care meet ANALYZE Intel® Distribution Apache Hadoop* Hardware-enhanced analytics platform to achieve insights faster
  • 15. Circumventing Security of Compromised Solutions in the Way of Healthcare • • • • • • 15 Slow encryption Vulnerable security Unusable 2-factor authentication Expensive security Compromised healthcare solutions Many [risky] alternatives! Intel Health & Life Sciences Where information and care meet
  • 16. Past • Security Trend Enabling Healthcare with More Usable and Secure Safeguard Solutions • Migrate software on general hardware • Separate security hardware core security logic to hardware • Integrate Security Software Security Software Core Security Logic Core Security Logic Trend General Purpose Hardware Core Security Logic • Robust Future separate security hardware • Performant, e.g., encryption Separate Security Hardware General Purpose Hardware (hardened), e.g., advanced behavior / heuristics anti-malware • Usable, e.g., manageable systems “just work,” 2-factor authentication • Cost 16 effective Performance, Robustness, Usability, Cost Time Intel Health & Life Sciences Where information and care meet Better
  • 17. Global Net Access Health (GNAX Health) is a leading healthcare technology infrastructure provider Learn more at www.gnaxhealth.com Key Challenges • Launch New Cloud Services to meet growing demand from healthcare organizations for flexible, costeffective, outsourced IT • Provide a Trusted Environment that helps providers protect sensitive information and comply with regulations Solution • Infrastructure based on Intel® Xeon E5 servers • Integrated Intel® AES-NI technology improved encryption performance by 49.25% (1.97x) and improved decryption performance by 62.16% (2.64x) • AES-NI hardened against side channel attacks and associated exploits AES -NI is a set of instructions that consolidates mathematical operations used in the Advanced Encryption Standard (AES) algorithm. Enabling AES-NI requires a computer system with an AES-NI-enabled processor as well as non-Intel software to execute the instructions in the correct sequence. For availability of AES-NI enabled processors or systems, check with your reseller or system manufacturer. 17 Intel Health & Life Sciences Where information and care meet
  • 18. Summary • Healthcare is undergoing a rapid transformation • Agile organizations will be best positioned to adapt quickly to this changing environment • Cloud computing can enable agile, cost effective, and highly available solutions… but ensuring security and compliance concerns are addressed is paramount • Intel is working with fellow travelers to produce secure, high performance, cloud solutions that help meet compliance and integration needs of the healthcare industry 18 Intel Health & Life Sciences Where information and care meet
  • 19. Additional Resources chris.s.gough@intel.com Secure Cloud for Healthcare Data Atlantic Health System Harnesses Data Growth CareAlign Exchange Secures Healthcare Data (ICA - AES-NI) Intel TXT Enables a Trusted, High Performance Cloud (DuPont) Building a Cloud For Healthcare (GNAX – AES-NI) High Performance Encryption for EHR Databases Big Data Technologies for Ultra-High-Speed Data Transfer & Processing (Aspera/Intel) • Cycle Computing – Utility HPC – Cloud Slam 2013 • GE Medical Quality Improvement Consortium (Private Cloud) • • • • • • • • 19 Intel Health & Life Sciences Where information and care meet
  • 20. Legal Information Today’s presentations contain forward-looking statements. All statements made that are not historical facts are subject to a number of risks and uncertainties, and actual results may differ materially. Please refer to our most recent Earnings Release and our most recent Form 10-Q or 10-K filing for more information on the risk factors that could cause actual results to differ. If we use any non-GAAP financial measures during the presentations, you will find on our website, intc.com, the required reconciliation to the most directly comparable GAAP financial measure. INFORMATION IN THIS DOCUMENT IS PROVIDED “AS IS”. NO LICENSE, EXPRESS OR IMPLIED, BY ESTOPPEL OR OTHERWISE, TO ANY INTELLECTUAL PROPERTY RIGHTS IS GRANTED BY THIS DOCUMENT. INTEL ASSUMES NO LIABILITY WHATSOEVER AND INTEL DISCLAIMS ANY EXPRESS OR IMPLIED WARRANTY, RELATING TO THIS INFORMATION INCLUDING LIABILITY OR WARRANTIES RELATING TO FITNESS FOR A PARTICULAR PURPOSE, MERCHANTABILITY, OR INFRINGEMENT OF ANY PATENT, COPYRIGHT OR OTHER INTELLECTUAL PROPERTY RIGHT. Software and workloads used in performance tests may have been optimized for performance only on Intel microprocessors. Performance tests, such as SYSmark and MobileMark, are measured using specific computer systems, components, software, operations and functions. Any change to any of those factors may cause the results to vary. You should consult other information and performance tests to assist you in fully evaluating your contemplated purchases, including the performance of that product when combined with other products. Intel product plans in this presentation do not constitute Intel plan of record product roadmaps. Please contact your Intel representative to obtain Intel's current plan of record product roadmaps. Intel's compilers may or may not optimize to the same degree for non-Intel microprocessors for optimizations that are not unique to Intel microprocessors. These optimizations include SSE2, SSE3, and SSE3 instruction sets and other optimizations. Intel does not guarantee the availability, functionality, or effectiveness of any optimization on microprocessors not manufactured by Intel. Microprocessor-dependent optimizations in this product are intended for use with Intel microprocessors. Certain optimizations not specific to Intel microarchitecture are reserved for Intel microprocessors. Please refer to the applicable product User and Reference Guides for more information regarding the specific instruction sets covered by this notice. Notice revision #20110804 All products, computer systems, dates, and figures specified are preliminary based on current expectations, and are subject to change without notice. Intel processor numbers are not a measure of performance. Processor numbers differentiate features within each processor family, not across different processor families. Go to: http://www.intel.com/products/processor_number Intel, processors, chipsets, and desktop boards may contain design defects or errors known as errata, which may cause the product to deviate from published specifications. Current characterized errata are available on request. Intel® Virtualization Technology requires a computer system with an enabled Intel® processor, BIOS, virtual machine monitor (VMM). Functionality, performance or other benefits will vary depending on hardware and software configurations. Software applications may not be compatible with all operating systems. Consult your PC manufacturer. For more information, visit http://www.intel.com/go/virtualization No computer system can provide absolute security under all conditions. Intel® Trusted Execution Technology (Intel® TXT) requires a computer system with Intel® Virtualization Technology, an Intel TXT-enabled processor, chipset, BIOS, Authenticated Code Modules and an Intel TXT-compatible measured launched environment (MLE). Intel TXT also requires the system to contain a TPM v1.s. For more information, visit http://www.intel.com/technology/security Intel, Intel Xeon, Intel Atom, Intel Xeon Phi, Intel Itanium, the Intel Itanium logo, the Intel Xeon Phi logo, the Intel Xeon logo and the Intel logo are trademarks or registered trademarks of Intel Corporation or its subsidiaries in the United States and other countries. Other names and brands may be claimed as the property of others. Copyright © 2013, Intel Corporation. All rights reserved. 20 Intel Health & Life Sciences Where information and care meet