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Dr.Roopchand.PS
Senior Resident Academic
Department of Neurology
TDMC, Alappuzha

NEURORADIOLOGY - IIH
INTRODUCTION:
 A disorder of unknown etiology.
 Affects young obese females
 Presents with features of raised ICT and
  papilledema.
 Otitic hydrocephalus – pre imaging era
 Pseudotumor ceribri –
  pneumatoencephalogram era
 Benign intracranial hypertension ? Vision
 Idiopathic intracranial hypertension.
DIAGNOSTIC CRITERIA:
   Modified Dandy criteria
     Signs and symptoms of raised ICT
     No localizing neurologic signs (exception of a
      unilateral or bilateral sixth nerve paresis)
     CSF may show increased pressure, but no cytologic
      or chemical abnormalities.
     Normal to small symmetric ventricles
     Diagnostic lumbar puncture done with the patient in
      the lateral decubitus position.
     MRI or MRV should be included to rule out
      intracranial venous sinus thrombosis.
     Other causes of intracranial hypertension should be
      ruled out
PATHOPHYSIOLOGY:

   Collapsible Dural venous sinuses

   Increased arterial blood flow.

   Obesity: increased intra abdominal pressure.
ETIOLOGY:

 Exposure to or withdrawal of drugs.
 Systemic diseases

 Disruption of cerebral venous flow

 Certain endocrine or metabolic disorders
CRITERIA FOR INCLUDING A DRUG OR A
DISEASE AS A CAUSE OF IIH:
   Radhakrishnan et al..
     At  least 2 cases should have been described
     The reported cases should have met all the
      criteria for the diagnosis of IIH.
     Intracranial dural sinus thrombosis should have
      been ruled out with reasonable certainty

Radhakrishnan K, Ahlskog JE, Garrity JA, Kurland LT. Idiopathic intracranial
hypertension. Mayo Clin Proc. Feb 1994;69(2):169-80
PNEUMOENCEPHALOGRAM:
CT FINDINGS:




 Optic nerve edema due to iih
                                Slit like ventricles
MRI:
pappilloedema, enlarged perioptic csf spaces with mild tortuosity of optic nerves,
empty sella , prominent suprasellar cistern
Posterior scleral flattening
Empty sella in IIH
Brain MRI (1.5
Tesla). (a)
Sagittal T2-
weighted
image
showing
empty sella
(white arrow);
(b) axial T2-
weighted
image
showing
buckling of
optic nerves
with normal
retro-orbital
structures; (c)
coronal T2-fat
saturated
image
showing
increased CSF
spaces
around
bilateral optic
nerves; (d) T1
post-contrast
coronal image
Neuroradiology of idopathic Intracranial Hypertension
Neuroradiology of idopathic Intracranial Hypertension

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Neuroradiology of idopathic Intracranial Hypertension

  • 1. Dr.Roopchand.PS Senior Resident Academic Department of Neurology TDMC, Alappuzha NEURORADIOLOGY - IIH
  • 2. INTRODUCTION:  A disorder of unknown etiology.  Affects young obese females  Presents with features of raised ICT and papilledema.  Otitic hydrocephalus – pre imaging era  Pseudotumor ceribri – pneumatoencephalogram era  Benign intracranial hypertension ? Vision  Idiopathic intracranial hypertension.
  • 3. DIAGNOSTIC CRITERIA:  Modified Dandy criteria  Signs and symptoms of raised ICT  No localizing neurologic signs (exception of a unilateral or bilateral sixth nerve paresis)  CSF may show increased pressure, but no cytologic or chemical abnormalities.  Normal to small symmetric ventricles  Diagnostic lumbar puncture done with the patient in the lateral decubitus position.  MRI or MRV should be included to rule out intracranial venous sinus thrombosis.  Other causes of intracranial hypertension should be ruled out
  • 4. PATHOPHYSIOLOGY:  Collapsible Dural venous sinuses  Increased arterial blood flow.  Obesity: increased intra abdominal pressure.
  • 5. ETIOLOGY:  Exposure to or withdrawal of drugs.  Systemic diseases  Disruption of cerebral venous flow  Certain endocrine or metabolic disorders
  • 6. CRITERIA FOR INCLUDING A DRUG OR A DISEASE AS A CAUSE OF IIH:  Radhakrishnan et al..  At least 2 cases should have been described  The reported cases should have met all the criteria for the diagnosis of IIH.  Intracranial dural sinus thrombosis should have been ruled out with reasonable certainty Radhakrishnan K, Ahlskog JE, Garrity JA, Kurland LT. Idiopathic intracranial hypertension. Mayo Clin Proc. Feb 1994;69(2):169-80
  • 8. CT FINDINGS: Optic nerve edema due to iih Slit like ventricles
  • 10. pappilloedema, enlarged perioptic csf spaces with mild tortuosity of optic nerves, empty sella , prominent suprasellar cistern
  • 13. Brain MRI (1.5 Tesla). (a) Sagittal T2- weighted image showing empty sella (white arrow); (b) axial T2- weighted image showing buckling of optic nerves with normal retro-orbital structures; (c) coronal T2-fat saturated image showing increased CSF spaces around bilateral optic nerves; (d) T1 post-contrast coronal image