Presentado en Cochabamba - Bolivia sobre el Síndrome post parada cardica "quinto eslabón en la RCP".

2. Cochabamba - Bolivia 2011 Dr. Roberto E. Gutiérrez Dorado Medicina Crítica y Terapia Intensiva

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29. ¿Cuando? ¿Durante cuánto tiempo? ¿Hasta qué temperatura? y ¿A qué velocidad? ¿Cómo monitorizar la temperatura?

30. La administración de cristaloides 30–40 ml/kg e nfriados a 4 ºC. (SFL 0,9% o solución RL). + Bolsas de hielo Técnicas de superficie. Técnicas endovasculares. Se recomienda a 0,25 – 0,5 ºC por hora.

31. Michael Holzer, M.D. Targeted Temperature Management for Comatose Survivors of Cardiac Arrest . N Engl J Med 2010;363:1256-64 .

34. Sistema intravascular Coolgard Alsius®

35. Anna Finley Caulfield, et al, Comparison of Cooling Techniques to Treat Cardiac Arrest Patients with Hypothermia . Stroke Research and Treatment Volume 2011, Article ID 690506, 6 pages doi:10.4061/2011/690506

36. Andreas Schneider, Bernd W. Böttiger, Erik Popp. Cerebral Resuscitation After Cardiocirculatory Arrest . Anesth Analg 2009;108:971–9

37. Muerte neuronal retardada, después de la isquemia cerebral global Neuronas piramidales del hipocampo (Ratas) después de 10 minutos de isquemia cerebro transitoria. HIP CA1 24 Horas 36 Horas 48 Horas CA1 CA3 DG

38. 10 min. 1 h. 6 h. HT local cabeza. HT Sistémica. Emanuela Keller, Regina Mudra, Christoph Gugl, Martin Seule, Susanne Mink, Juerg Fröhlich. Theoretical evaluations of therapeutic systemic and local cerebral hypothermia . Journal of Neuroscience Methods Volume 178, April 2009, 345-349 HT local cuello.

39. Wolfgang Weihs, Alexandra Schratter, Fritz Sterz,∗, Andreas Janata, Sandra Högler, Michael Holzer, Udo M. Losert, Harald Herkner, Wilhelm Behringer. The importance of surface area for the cooling efficacy of mild therapeutic hypothermia . Resuscitation 82 (2011) 74–78

40. Maaret Castrén. Intra-Arrest Transnasal Evaporative Cooling A Randomized, Prehospital, Multicenter Study (PRINCE: Pre-ROSC IntraNasal Cooling Effectiveness) . Circulation. 2010;122:729-736.

41. Florence Dumas, et al. Immediate Percutaneous Coronary Intervention Is Associated With Better Survival After Out-of-Hospital Cardiac Arrest : Insights From the PROCAT (Parisian Region Out of Hospital Cardiac Arrest) Registry . Circ Cardiovasc Interv 2010;3;200-207

42. Bernd W. Böttiger, Et al. for the TROICA Trial Investigators and the European Resuscitation Council Study Group* . Thrombolysis during resuscitation for out-of-hospital cardiac arrest. N Engl J Med. 2008;359:2651–62. 9;53:409–15.

43. Matthias Götberg. A Pilot Study of Rapid Cooling by Cold Saline and Endovascular Cooling Before Reperfusion in Patients With ST-Elevation Myocardial Infarction . Circ Cardiovasc Interv. 2010;3:400-407.

44. L.M. Batista et al. Feasibility and safety of combined percutaneous coronary intervention and therapeutic hypothermia following cardiac arrest . Resuscitation 81 (2010) 398–403

45. Tortorici MA, Kochanek PM, Poloyac SM. Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia mediated alterations on the cytochrome P450 enzyme system. Crit Care Med. 2007;35:2196–204.

46. Michael Holzer, M.D. Targeted Temperature Management for Comatose Survivors of Cardiac Arrest . N Engl J Med 2010;363:1256-64.

47. Tortorici MA, Kochanek PM, Poloyac SM. Effects of hypothermia on drug disposition, metabolism, and response: A focus of hypothermia mediated alterations on the cytochrome P450 enzyme system. Crit Care Med. 2007;35:2196–204.

48. Wijdicks EFM, Hijdra A, Young GB, et al. Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidencebased review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006; 67:203-10.

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50. Dion Stub, Stephen Bernard, Stephen J. Duffy and David M. Kaye. Post Cardiac Arrest Syndrome: A Review of Therapeutic Strategies . Circulation 2011;123;1428-1435 .