1. Raj Kiran Medapalli, MD, MPH. Nephrology Fellow January 5 th 2011 Mount Sinai School of Medicine Division of Nephrology Journal Club

2. Transplant Nephrectomy Improves Survival following a Failed Renal Allograft . JASN 21: 374–380, 2010. Journal Club January 5 th 2011 Raj Kiran Medapalli, MD, MPH.

5. Death after primary renal allograft loss 78564 pts who underwent primary renal transplant between 1988-1998; 10 yr follow-up. USRDS In comparison, annual death rate on renal transplant waiting list is 6.33% per 100-pt-years (9.27% for diabetics) Annual adjusted death rates per 100 pt-years Death with functioning transplant Death after graft loss N Annual rate % N Annual rate % Overall 10816 2.81 4712 9.42 Cardio-vasc 3402 0.69 2252 4.31 Infectious 1856 0.37 879 1.63 Malignancy 808 0.19 122 0.11

6. Source: Kaplan and Meier-Kriesche. AJT 2002; 2: 970-74

25. b Defined as need for dialysis before hospital discharge after transplantation.

27. d Coded during any hospitalization occurring after return to dialysis after failed kidney transplant.

29. Unadjusted Rates (1994-2004) All-cause mortality Total N=10,951 32 vs. 36 per 100 Person Years (p=0.0324) Repeat transplantation Total N=10,951 10% vs. 4.1% (p<0.001)

31. Adjusted rates + Sensitivity Analysis