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Preventing

infectious

complications in the
Practice
surgery

of

maxillofacial

Dr Rishi Bali
Professor , OMFS ,
DAV Centenary DC & H


Three main causes :



Anaesthesia



Hemorrhage



Infection
Maxillofacial infections ? Considerations ?
• Proximity to vital organs & siginificant mortality
• Medically compromised patients
• Antibiotic resistant bacteria


Fascial space infections



Fungal infections



Sepsis & Septic shock
Brain abscess, cavernous sinus
thrombosis,Orbital cellulitis

Upward spread

Systemic spread

SPACE INFECTIONS

Septicemia,DIC

Downward spread

Resp.
obstr
,Aspiration
Pneumonia,Pneumothorax,Mediastinitis
Pericarditis,Thoracic Empyema


Described in
relation to the
hyoid
◦ Suprahyoid
◦ Infrahyoid
◦ Entire length of
the neck
 Superior—skull base
 Inferior—hyoid
 Posterior—prevertebral
fascia
 The
stylopharyngeal
aponeurosis
of
Zuckerkandel : barrier
to infection from the
pre to the post styloid
compartment.
 Carotid sheath contributions
from all 3 layers of deep fascia
& can be secondarily infected
Airway
obstruction,
pneumothorax, Mediastinitis,
Horner’s
syndrome,
IJV
thrombophlebitis,LeMierre
syndrome

 Communicates
retropharyngeal space

with


39 yrs pregnant pt Lt Submandibular Pterygomand
peritonsillar & Parapharyngeal infection



Mild airway compromise , TLC 18,500 , BP 92/50
,HR 120 , Temp 102, RR 21/min



Focus removal - I&D



Patient died

?
?
TRIAGE : Occult
Obvious distress,
Near total obstruction
Fiberoptic intubation
Tracheotomy under LA If FB/ skilled anaesthetist not available
Needle decompression before airway control
Avoid Blind nasal intubation
IMAGING


Lateral neck film (6 at
2 & 22 at 6 )
False negative rate 33%



CECT is the imaging
of choice

12
Cavernous Sinus Thrombosis (CST)
•Periorbital edema, headache, photophobia,
proptosis,ptosis , chemosis, 3 to 6 cranial nerve palsies VI

nerve earliest.
•Sluggish pupillary reaction
•Sensory deficits of the opth & max div of the fifth nerve .

•Headache , Nuchal rigidity & Sepsis.
Fungal sinusitis
• Reported with increasing frequency
• Invasive form : associated
morbidity & mortality

with

significant


No propotosis after 3 months of

Voriconazole

therapy


Reversal of immunocompromised state



Early intervention & antifungals based on micro.



Accurate Assesment of spread : aggressive Surgery



Regular follow up with imaging for minimum of one
year

Singh V ,Bali R. Rhinocerebral mucormycosis : A diagnostic challenge & therapeutic dilemma . JOMS2012 June;70(6):1369


Facial swelling & Pain



Opthalmoplegia& blurred vision
Lt interpositional arthroplasty in 7 yr male
Blood loss approx. 250 ml & Uneventful extubation

Post op. phase hypotension 98/58 mmhg.
• Hemoglobin 10 .4gm %
• Drain & surgical site were evaluated
• Fast NS followed by colloids
• Blood transfusion 1 unit started 10 hrs after the surgery
TEMPERATURE
103
102
101

RESPIRATORY RATE
30
25

100

20

99

15

98

10

97

5

96

0
WBC

120

25000

100

20000

80

15000
10000
5000
0

60
40
20
0

SYSTOLIC

DIASTOLIC
Infection

SIRS

Sepsis
Severe Sepsis

Ref : Bone et al. Chest. 1992;101:1644-1654.
70%
60%
50%
40%

SIRS

30%

SEPSIS

SEVERE SEPSIS

20%

SEPTIC SHOCK

10%

0%
SIRS

SEPSIS

SEVERE

SEPTIC

SEPSIS

SHOCK
Altered
Consciousness

Tachypnea
PaO2 250

Liver Enzymes
>2x ULN

Tachycardia
SBP 90 despite
fluids

Urine Output <0.5
mL/kg/hr despite fluids
Creatinine

Platelets
<100,000/mm3
PTT≥60

Low pH with high lactate
(lactate>2mMol)
Balk RA. Crit Care Clin. 2000;16:179-192.
◦ CRP , Blood Glucose
◦ Leukocytosis or Leukopenia
◦ Toxic granulation of neutrophils & band forms
◦ Arterial Blood gases
◦ Cultures : Blood / Pus


http://www.survivingsepsis.org/campaign


Sound knowledge of

pathophysiology of

infectious processes ,the ability to diagnose
early , anticipate complications & decisively
interrupt them can prevent many morbidities
& mortalities in Maxillofacial surgery
Infectitious complications in the practice of maxillofacial surgery

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Infectitious complications in the practice of maxillofacial surgery

Hinweis der Redaktion

  1. Due to the proximity of the central nervous system and respiratory passages, timely efforts are required to diagnose and properly manage maxillofacial infections. Do not underestimate maxillofacial infections”Multiple severe complications of OI have been reported, such as airwayobstruction , mediastinitis , necrotizing fascitis, cavernous sinus thrombosis, sepsis,thoracic empyema, cerebral abscess and osteomyelitis.
  2. Superficial spacePrevertebral spaceRetropharyngeal spaceDanger spaceVisceral vascular space
  3. Posterior to pharynx and esophagusAnterior border is alar layer of deep fasciaPosterior border is prevertebral layerExtends from skull base to diaphragm and is so named because it contains loose areolar tissue and offers little resistance to the spread of infectionAnterior to alar layer of deep fasciaExtends from skull base to T1-T2
  4. Goal is to identify the urgencyORD :pts at risk after sedative medication or manipulation. Trismus ,reactive airway edema .Depressed airway that can not be protected .proximity of surgical site entails risk of aspiration of purulent material .
  5. Magnetic resonance image showing bilateral retroseptal infection with intracranial extension involving the meninges of thetemporal lobes and cavernous sinus and a left temporal space abscess.Desa and Green. Cavernous Sinus Thrombosis. J Oral MaxillofacSurg 2012.
  6. Dental origin -7% of all cases of CST.The infection can begin with unilateral involvement, but can develop bilaterally through the circular sinus. The cavernous sinuses and their connections are devoid of valves, consequently bidirectional spread of infection, and thrombi can occur throughout this network. Organisms may reach the cavernous sinus from the face by an anterograde route along ophthalmic veins connected to angular veins, or by a retrograde route along emissary veins connected to the pterygoid venous plexus. Contrast enhanced CT scan may reveal the primary source of infection, thickening of the superior ophthalmic vein and irregular filling defects in the cavernous sinus
  7. Let us see how the changes occurs in the form of proptosis during course of treatment
  8. Negatively stained hyphae
  9. If the source of immunocompromise state can not be reversed. Then the other adjuncts are almost always ineffectual.Microbiological :Culture,PCR &amp; DNA Probes
  10. Zygomatic swing osteotomy