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Body CT 
for Emergency Physicians	

Rathachai Kaewlai, MD	

Division of Emergency Radiology	

Department of Radiology, Ramathibodi Hospital, Bangkok,Thailand	

Annual Conference ofThai Emergency Physicians (ACTEP)	

25 Nov 2015 at the Regent Cha-am Beach Resort, Cha-am, Petchaburi,Thailand
Outline	

About emergent body CT	

Vascular occlusion	

Aneurysm/pseudoaneurysm	

Bleeding and active contrast extravasation	

Extraluminal air
CT Contrast: Update	

Post contrast acute kidney injury (PC-AKI) 	

	

Creatinine change in 48 hours after IV contrast	

	

Various etiologies: physiologic variation, drugs, CM	

Contrast induced nephropathy (CIN)	

	

Subset of PC-AKI	

	

Exists but likely rare, unknown prevalence	

eGFR more commonly used than serum creatinine
CT Contrast: Update	

21346 patients undergone CT, half received IV contrast	

1:1 matched on propensity score yielding similar demographics
and comorbidities	

Radiology 	

December 2014
IV Contrast: When?	

Chest: most emergent indications	

Abdomen: most emergent indications except ureteric
stone, R/O AAA rupture, R/O free air	

CTisUS.com
Oral Contrast: When?	

Generally not recommended in ER setting except for	

	

Penetrating abdominal trauma	

	

Suspected GI ïŹstula, postoperative leakage	

	

Suspected esophageal perforation	

Take time (1-2 hours)	

Value questioned even in suspected bowel perforation	

Role of “limited” oral contrast?	

emrap.org
Rectal Contrast: When?	

Generally not recommended in ER setting except for:	

	

Penetrating abdominal trauma	

	

Suspected GI ïŹstula, postoperative leakage	

May be used in	

	

Suspected appendicitis esp in children	

WorkïŹ‚ow and job issue	

Patient discomfort	

oakmed.co.uk
Timing of Acquisition: 
What  Why?	

NCCT 	

CTA 	

arterial 	

venous 	

delayed	

ARTERIAL	

VENOUS	

CTA
Scan Coverage: CTA Aorta	

Whole aorta	

	

R/O dissection (assess extent)	

	

R/O aortic aneurysm w/o prior
imaging (potential coexisting
aneurysms)	

One part OK	

	

 	

R/O AAA rupture	

	

F/U known aneurysm
Scan Coverage: CTA for PE	

With lower extremity (LE) CTV	

	

Older patients	

	

No worry on volume of IV contrast
(kidneys, CHF)	

Without LE CTV	

	

Younger patients	

	

Do Doppler (similar accuracy as CTV)	

ehumanbioïŹeld.wikispaces.com
Scan Coverage: Abdominal CT	

Most ER indications !
whole abdomen	

	

Pancreatitis	

	

Colon problems	

Upper abdomen:
Hepatobiliary problems	

Lower abdomen:Appendix	

KUB: Stone protocol
Scan Coverage: Multiphase CT	

Should avoid in young patients (45 years)	

For most ER indications, venous phase is enough	

	

Pretty much depending on your radiologists’ level of
comfort and experience	

Required for	

	

Bowel ischemia	

	

Characterization of masses or suspected masses
Scan Coverage: Non-contrast	

Do we always need non-contrast before giving IV CM?	

	

No!	

Most people worries that IV contrast will obscure
blood and Ca2+, it’s partly true BUT we can still
diagnose blood and dense Ca2+ on post-contrast CT	

We do this if it is multiphase scan	

	

Bowel ischemia	

	

Characterization of masses or suspected masses
NCCT Only	

eGFR 30 without dialysis unless risk accepted by
referring physician and patient	

Acute ïŹ‚ank pain	

R/O AAA rupture	

	

May need IV contrast if patient’s conditions allow	

R/O free air	

Looking for lung lesions, bone lesions
Scan Coverage: Trauma CT	

Trauma CT is different than other CTs	

	

Coverage: torso coverage in abdominal trauma	

	

Arterial phase necessary: active contrast
extravasation	

	

No need for non-contrast phase	

Reduced radiation dose because many trauma victims
are young (higher risk of radiation-induced cancers)
Approach to CT Interpretation	

Clinical question ïŹrst ! look for pathology suspected	

Then ! systematic review of images	

Check blind spots of each exam	

(Knowing body anatomy is a prerequisite!)
Critical CT Findings	

Vascular occlusion	

Bleeding and active contrast extravasation	

Extraluminal air
VASCULAR OCCLUSION	

“Filling defect” and mimics	

Acute vs. non-acute occlusion	

Effects of occlusion
Intravascular Filling Defect	

Intraluminal ïŹlling defect(s)
with sharp interface with
intravascular contrast
material	

Acute pulmonary emboli
SMA/SMV Thrombus	

Superior mesenteric artery thrombus	

Superior mesenteric vein thrombus	

with bowel dilatation/thickening, likely
ischemia
Deep Vein Thrombosis	

DVT of the left femoral vein
Pseudo-ïŹlling Defect	

Not sharp	

Not that hypodense	

Outside vessels	

Pseudo-ïŹlling defect in bilateral femoral veins 	

2/2 heterogeneous contrast opaciïŹcation	

Interlobar lymph nodes
Acute Filling Defect	

Peripheral ïŹlling defect acute angled with arterial wall	

Partial, central ïŹlling defect	

	

Polo mint	

	

Railway tract	

Normal or enlarged vessel diameter	

Perivascular soft tissue stranding
Changes 2/2 Occlusion	

Proximal to site of vascular occlusion – high pressure	

At site of vascular occlusion – attempt to reperfuse	

Distal to site of vascular occlusion – infarction 	

(proximal/distal = relative to blood ïŹ‚ow)
ANEURYSM/
PSEUDOANEURYSM	

Fusiform vs. saccular	

Rupture?	

Infected?
Aneurysm/pseudoaneurysm:
DeïŹnitions	

Fusiform 1.5X of
expected diameter	

Any saccular and pseudo-	

(1.1x-1.4x = ectasia)	

UFHealth.org
Pseudoaneurysm: Aortic Injury	

*	
  
*	
  
Pseudoaneurysm with surrounding hematoma	

of the proximal descending 	

thoracic aorta 2/2 blunt trauma
Fusiform Aneurysm: Aorta	

Thoraco-abdominal fusiform aneurysm
with partial thrombosis and ulcer within
the thrombus	

Partially thrombosed AAA
Saccular Aneurysm: Aorta	

Saccular aneurysm of the aortic arch with partial thrombosis
“Impending” AAA Rupture	

 Hyperdense crescent	

Sensitivity 77%, speciïŹcity
93%, PPV 53%	

Focal discontinuity of intimal
calciïŹcation	

Tangential calcium sign	

Bottom-row images from Radiologyassistant.nl
BLEEDING AND ACTIVE
CONTRAST EXTRAVASATION	

Blood density on CT	

Blood in free spaces and conïŹned spaces	

Active bleeding
Blood on CT	

Shades of gray	

Air Fat CSF Water CM Bone Metal	

-1000 0 15 1000 HU	

Description relative to organs where blood is located	

CT attenuation of blood products depends on location,
mixture (i.e., with CSF), initial hematocrit and time from
onset of bleeding
Hematocrit Effect	

35-45
HU	

Whole blood = cells + plasma	

55-65%
Plasma
Erythrocytes
35-45%
Leukocytes	
  
And	
  platelets	
  
0-10 HU	

60-90 HU
Location of Blood	

Potential spaces	

	

Pleural, pericardial, peritoneal	

ConïŹned spaces (organs, structures)	

	

Mediastinum, chest wall	

	

Solid organs	

	

Hollow viscus
Hemothorax	

Mostly from trauma	

Hemithorax holds up to
4L – enough for
exsanguination	

Clotting may occur quickly	

Traumatic left hemothorax	

*	
  
Mediastinal Hemorrhage	

Trauma	

Vascular/cardiac rupture
and dissection	

Coagulopathy	

Traumatic aortic pseudoaneurysm	

“Traumatic aortic injury”	

*	
  
Hemoperitoneum	

Most dependent portions	

	

Abdomen: hepatorenal	

	

Pelvis: cul-de-sac	

Ruptured ovarian cyst	

*	
  
*	
  
*	
  
Sentinel Clot 	

Clots develop at site of
bleeding (sentinel)	

Higher density (45-80 HU)
compared to blood
elsewhere (25-45 HU)	

Probable site of bleeding	

Ruptured GI stromal tumor of stomach	

**	
  
*	
  
Retroperitoneal Hemorrhage	

Around retroperitoneal
organs/structures	

Ruptured AAA	

*	
  
*	
  
Active Contrast Extravasation	

Jet or focal area of contrast
in hematoma 	

High density mostly 100 HU	

*	
  
*	
  
Active Contrast Extravasation	

Changing appearance and/or density on delayed images	

*	
   *	
   *	
  
*	
  
*
*	
  
Active Contrast Extravasation	

SigniïŹcant bleeding	

May require IV ïŹ‚uid, blood transfusion, embolization or
surgery depending on clinical factors lifesaving
surgical or endovascular Rx
EXTRALUMINAL AIR	

Air in extraluminal spaces	

Mimics
Extraluminal Air	

“Something bad is going on.”	

Mostly indicative of surgical emergency	

CT best to detect small extraluminal air and may be
able to deïŹne the etiology
Pneumothorax	

Gas in pleural cavity thru
chest wall or lung
across visceral pleura	

No lung tissues	

Much lower density
(lower than -1000 HU)	

CT most reliable for
diagnosis but should not
be routine	

*	
  
*	
  
Pneumothorax	

Look for signs of possible tension on CT - best on coronal view	

	

Mediastinal shift to contralateral side, ïŹ‚at/inverted diaphragm	

	

“Clinical” diagnosis	

*	
  *	
  
*	
  
*	
  
*	
  
*	
  
Pneumothorax	

Supine position – anterior,
medial location	

*	
  
Pneumomediastinum	

Sources:	

	

Airways	

	

Esophagus	

	

Lungs	

	

Track from neck or
abdomen	

Presumed alveolar rupture – Macklin effect
Pneumomediastinum	

Concerning if:	

	

Fluid in mediastinum	

	

Localized around
airways or esophagus	

Leakage of esophageal
contrast	

Spontaneous esophageal perforation	

*	
  
*	
  
Pneumopericardium	

Thoracic surgery	

Pericardial drainage	

Trauma	

Gas-forming infection	

Fistula to esophagus/
stomach	

Image from Polhill et al. JTrauma 2009; 66(4)	

*	
   *	
  
In the Abdomen:	

Perforated duodenal ulcer	

Colonic pneumatosis	

Look for
extraluminal air
in lung window
Intraperitoneal vs. Retroperitoneal	

52	
  
*	
  *	
  
*	
  
*	
  
Intraperitoneal air. Smallest amount in the
anterior, non-dependent portion, mostly
in RUQ	

Retroperitoneal air outlining
retroperitoneal organs
Pneumatosis vs. Intraluminal	

53	
  
Pneumatosis intestinalis – colon	

Air in the wall, dependent portion, 	

separated from luminal content	

Small bowel feces in the lumen of small bowel loops
Portal Venous vs. Biliary Air	

54	
  
Portal venous gas	

With	
  pneumatosis,	
  PVG	
  is	
  likely	
  2/2	
  necro?c	
  bowel	
  
Pneumobilia	

Common:	
  Incompetent	
  sphincter	
  of	
  Oddi,	
  recent	
  
instrumenta?on:	
  ERCP,	
  surgery,	
 Â ïŹstula	
  with	
  GI	
  tract	
  
Rare:	
  gas-­‐forming	
  infec?on	
  
Periphery of liver	

More branching	

Central of liver	

Few number of branches
Intraperitoneal Air	

Perforation Site	

 Amount	

Location	

Stomach/duodenum	

 Abundant	

 Around liver and stomach	

Small bowel	

 Small	

 Mesenteric folds, around liver	

Appendix	

 Small/absent	

 Around appendix	

Large bowel	

 Variable	

Pelvis, mesenteric folds,
retroperitoneal space
Retroperitoneal Air	

Perforation of:	

	

Duodenum	

	

Colon: asc/descending	

	

Rectum	

Post retroperitoneal Sx
Pneumatosis Intestinalis	

Variables1	

 Odds ratio	

Peritoneal signs	

 9.40	

Age 60 years	

 3.00	

Portal venous gas and
pneumatosis	

2.52	

Ascites	

 1.92	

1Hani MB, et al. J Surgical Res 2013;185:581.	

!  Utility of CT appearance
questioned	

!  Mesenteric fat stranding	

!  Bowel wall thickening
Where Air Is Coming From?	

Outside	

	

Trauma 	

	

Iatrogenic	

Produced there	

	

Gas-forming infection	

Nearby organs/structures	

	

Fistula to/from air-containing structures	

	

Extension from contiguous organs/structures
Summary	

Tips on ordering body CT in ER discussed	

Critical CT ïŹndings shown and discussed	

	

Vascular occlusion	

	

Aneurysm/pseudoaneurysm, 	

	

Blood and active contrast extravasation	

	

Extraluminal air
THANK YOU FOR YOUR
ATTENTION

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Body CT for Emergency Physicians

  • 1. Body CT for Emergency Physicians Rathachai Kaewlai, MD Division of Emergency Radiology Department of Radiology, Ramathibodi Hospital, Bangkok,Thailand Annual Conference ofThai Emergency Physicians (ACTEP) 25 Nov 2015 at the Regent Cha-am Beach Resort, Cha-am, Petchaburi,Thailand
  • 2. Outline About emergent body CT Vascular occlusion Aneurysm/pseudoaneurysm Bleeding and active contrast extravasation Extraluminal air
  • 3. CT Contrast: Update Post contrast acute kidney injury (PC-AKI) Creatinine change in 48 hours after IV contrast Various etiologies: physiologic variation, drugs, CM Contrast induced nephropathy (CIN) Subset of PC-AKI Exists but likely rare, unknown prevalence eGFR more commonly used than serum creatinine
  • 4. CT Contrast: Update 21346 patients undergone CT, half received IV contrast 1:1 matched on propensity score yielding similar demographics and comorbidities Radiology December 2014
  • 5. IV Contrast: When? Chest: most emergent indications Abdomen: most emergent indications except ureteric stone, R/O AAA rupture, R/O free air CTisUS.com
  • 6. Oral Contrast: When? Generally not recommended in ER setting except for Penetrating abdominal trauma Suspected GI ïŹstula, postoperative leakage Suspected esophageal perforation Take time (1-2 hours) Value questioned even in suspected bowel perforation Role of “limited” oral contrast? emrap.org
  • 7. Rectal Contrast: When? Generally not recommended in ER setting except for: Penetrating abdominal trauma Suspected GI ïŹstula, postoperative leakage May be used in Suspected appendicitis esp in children WorkïŹ‚ow and job issue Patient discomfort oakmed.co.uk
  • 8. Timing of Acquisition: What Why? NCCT CTA arterial venous delayed ARTERIAL VENOUS CTA
  • 9. Scan Coverage: CTA Aorta Whole aorta R/O dissection (assess extent) R/O aortic aneurysm w/o prior imaging (potential coexisting aneurysms) One part OK R/O AAA rupture F/U known aneurysm
  • 10. Scan Coverage: CTA for PE With lower extremity (LE) CTV Older patients No worry on volume of IV contrast (kidneys, CHF) Without LE CTV Younger patients Do Doppler (similar accuracy as CTV) ehumanbioïŹeld.wikispaces.com
  • 11. Scan Coverage: Abdominal CT Most ER indications ! whole abdomen Pancreatitis Colon problems Upper abdomen: Hepatobiliary problems Lower abdomen:Appendix KUB: Stone protocol
  • 12. Scan Coverage: Multiphase CT Should avoid in young patients (45 years) For most ER indications, venous phase is enough Pretty much depending on your radiologists’ level of comfort and experience Required for Bowel ischemia Characterization of masses or suspected masses
  • 13. Scan Coverage: Non-contrast Do we always need non-contrast before giving IV CM? No! Most people worries that IV contrast will obscure blood and Ca2+, it’s partly true BUT we can still diagnose blood and dense Ca2+ on post-contrast CT We do this if it is multiphase scan Bowel ischemia Characterization of masses or suspected masses
  • 14. NCCT Only eGFR 30 without dialysis unless risk accepted by referring physician and patient Acute ïŹ‚ank pain R/O AAA rupture May need IV contrast if patient’s conditions allow R/O free air Looking for lung lesions, bone lesions
  • 15. Scan Coverage: Trauma CT Trauma CT is different than other CTs Coverage: torso coverage in abdominal trauma Arterial phase necessary: active contrast extravasation No need for non-contrast phase Reduced radiation dose because many trauma victims are young (higher risk of radiation-induced cancers)
  • 16. Approach to CT Interpretation Clinical question ïŹrst ! look for pathology suspected Then ! systematic review of images Check blind spots of each exam (Knowing body anatomy is a prerequisite!)
  • 17. Critical CT Findings Vascular occlusion Bleeding and active contrast extravasation Extraluminal air
  • 18. VASCULAR OCCLUSION “Filling defect” and mimics Acute vs. non-acute occlusion Effects of occlusion
  • 19. Intravascular Filling Defect Intraluminal ïŹlling defect(s) with sharp interface with intravascular contrast material Acute pulmonary emboli
  • 20. SMA/SMV Thrombus Superior mesenteric artery thrombus Superior mesenteric vein thrombus with bowel dilatation/thickening, likely ischemia
  • 21. Deep Vein Thrombosis DVT of the left femoral vein
  • 22. Pseudo-ïŹlling Defect Not sharp Not that hypodense Outside vessels Pseudo-ïŹlling defect in bilateral femoral veins 2/2 heterogeneous contrast opaciïŹcation Interlobar lymph nodes
  • 23. Acute Filling Defect Peripheral ïŹlling defect acute angled with arterial wall Partial, central ïŹlling defect Polo mint Railway tract Normal or enlarged vessel diameter Perivascular soft tissue stranding
  • 24. Changes 2/2 Occlusion Proximal to site of vascular occlusion – high pressure At site of vascular occlusion – attempt to reperfuse Distal to site of vascular occlusion – infarction (proximal/distal = relative to blood ïŹ‚ow)
  • 26. Aneurysm/pseudoaneurysm: DeïŹnitions Fusiform 1.5X of expected diameter Any saccular and pseudo- (1.1x-1.4x = ectasia) UFHealth.org
  • 27. Pseudoaneurysm: Aortic Injury *   *   Pseudoaneurysm with surrounding hematoma of the proximal descending thoracic aorta 2/2 blunt trauma
  • 28. Fusiform Aneurysm: Aorta Thoraco-abdominal fusiform aneurysm with partial thrombosis and ulcer within the thrombus Partially thrombosed AAA
  • 29. Saccular Aneurysm: Aorta Saccular aneurysm of the aortic arch with partial thrombosis
  • 30. “Impending” AAA Rupture Hyperdense crescent Sensitivity 77%, speciïŹcity 93%, PPV 53% Focal discontinuity of intimal calciïŹcation Tangential calcium sign Bottom-row images from Radiologyassistant.nl
  • 31. BLEEDING AND ACTIVE CONTRAST EXTRAVASATION Blood density on CT Blood in free spaces and conïŹned spaces Active bleeding
  • 32. Blood on CT Shades of gray Air Fat CSF Water CM Bone Metal -1000 0 15 1000 HU Description relative to organs where blood is located CT attenuation of blood products depends on location, mixture (i.e., with CSF), initial hematocrit and time from onset of bleeding
  • 33. Hematocrit Effect 35-45 HU Whole blood = cells + plasma 55-65% Plasma Erythrocytes 35-45% Leukocytes   And  platelets   0-10 HU 60-90 HU
  • 34. Location of Blood Potential spaces Pleural, pericardial, peritoneal ConïŹned spaces (organs, structures) Mediastinum, chest wall Solid organs Hollow viscus
  • 35. Hemothorax Mostly from trauma Hemithorax holds up to 4L – enough for exsanguination Clotting may occur quickly Traumatic left hemothorax *  
  • 36. Mediastinal Hemorrhage Trauma Vascular/cardiac rupture and dissection Coagulopathy Traumatic aortic pseudoaneurysm “Traumatic aortic injury” *  
  • 37. Hemoperitoneum Most dependent portions Abdomen: hepatorenal Pelvis: cul-de-sac Ruptured ovarian cyst *   *   *  
  • 38. Sentinel Clot Clots develop at site of bleeding (sentinel) Higher density (45-80 HU) compared to blood elsewhere (25-45 HU) Probable site of bleeding Ruptured GI stromal tumor of stomach **   *  
  • 40. Active Contrast Extravasation Jet or focal area of contrast in hematoma High density mostly 100 HU *   *  
  • 41. Active Contrast Extravasation Changing appearance and/or density on delayed images *   *   *   *   * *  
  • 42. Active Contrast Extravasation SigniïŹcant bleeding May require IV ïŹ‚uid, blood transfusion, embolization or surgery depending on clinical factors lifesaving surgical or endovascular Rx
  • 43. EXTRALUMINAL AIR Air in extraluminal spaces Mimics
  • 44. Extraluminal Air “Something bad is going on.” Mostly indicative of surgical emergency CT best to detect small extraluminal air and may be able to deïŹne the etiology
  • 45. Pneumothorax Gas in pleural cavity thru chest wall or lung across visceral pleura No lung tissues Much lower density (lower than -1000 HU) CT most reliable for diagnosis but should not be routine *   *  
  • 46. Pneumothorax Look for signs of possible tension on CT - best on coronal view Mediastinal shift to contralateral side, ïŹ‚at/inverted diaphragm “Clinical” diagnosis *  *   *   *   *   *  
  • 47. Pneumothorax Supine position – anterior, medial location *  
  • 48. Pneumomediastinum Sources: Airways Esophagus Lungs Track from neck or abdomen Presumed alveolar rupture – Macklin effect
  • 49. Pneumomediastinum Concerning if: Fluid in mediastinum Localized around airways or esophagus Leakage of esophageal contrast Spontaneous esophageal perforation *   *  
  • 50. Pneumopericardium Thoracic surgery Pericardial drainage Trauma Gas-forming infection Fistula to esophagus/ stomach Image from Polhill et al. JTrauma 2009; 66(4) *   *  
  • 51. In the Abdomen: Perforated duodenal ulcer Colonic pneumatosis Look for extraluminal air in lung window
  • 52. Intraperitoneal vs. Retroperitoneal 52   *  *   *   *   Intraperitoneal air. Smallest amount in the anterior, non-dependent portion, mostly in RUQ Retroperitoneal air outlining retroperitoneal organs
  • 53. Pneumatosis vs. Intraluminal 53   Pneumatosis intestinalis – colon Air in the wall, dependent portion, separated from luminal content Small bowel feces in the lumen of small bowel loops
  • 54. Portal Venous vs. Biliary Air 54   Portal venous gas With  pneumatosis,  PVG  is  likely  2/2  necro?c  bowel   Pneumobilia Common:  Incompetent  sphincter  of  Oddi,  recent   instrumenta?on:  ERCP,  surgery, Â ïŹstula  with  GI  tract   Rare:  gas-­‐forming  infec?on   Periphery of liver More branching Central of liver Few number of branches
  • 55. Intraperitoneal Air Perforation Site Amount Location Stomach/duodenum Abundant Around liver and stomach Small bowel Small Mesenteric folds, around liver Appendix Small/absent Around appendix Large bowel Variable Pelvis, mesenteric folds, retroperitoneal space
  • 56. Retroperitoneal Air Perforation of: Duodenum Colon: asc/descending Rectum Post retroperitoneal Sx
  • 57. Pneumatosis Intestinalis Variables1 Odds ratio Peritoneal signs 9.40 Age 60 years 3.00 Portal venous gas and pneumatosis 2.52 Ascites 1.92 1Hani MB, et al. J Surgical Res 2013;185:581. !  Utility of CT appearance questioned !  Mesenteric fat stranding !  Bowel wall thickening
  • 58. Where Air Is Coming From? Outside Trauma Iatrogenic Produced there Gas-forming infection Nearby organs/structures Fistula to/from air-containing structures Extension from contiguous organs/structures
  • 59. Summary Tips on ordering body CT in ER discussed Critical CT ïŹndings shown and discussed Vascular occlusion Aneurysm/pseudoaneurysm, Blood and active contrast extravasation Extraluminal air
  • 60. THANK YOU FOR YOUR ATTENTION