Carcinoma of the endometrium is one of the most common gynecological cancers, especially in postmenopausal white women. There is no effective screening program. Risk factors include estrogen exposure, obesity, and nulliparity. Symptoms include postmenopausal bleeding. Diagnosis involves endometrial biopsy. Treatment depends on staging and includes surgery with radiation or chemotherapy for advanced cases. Prognosis depends on staging, histology, and treatment received.