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Integrated Strategy   for Dengue  Prevention and Control
The Global Impact of Dengue Virus Dengue Fever &  Dengue Hemorrhagic Fever Endemic in more  than 100 countries 50 million cases  each year Areas infested with  Aedes aegypti Areas with  Aedes aegypti  and dengue epidemic activity
Examples  of Emerging and Re-Emerging Infectious Disease: past 10 years A Fauci, NIAID/NIH, 2005
2 HIV Dengue H Papilloma v Ebola Hanta virus West Nile virus Tobacco Malaria Non- HIV tuberculosis Road accidents 3 5 6 Influenza Polio SARS vCJD Measles HBV + HCV 4 RSV, Rota virus 7 Hospital infection Suicide Major and minor killers: global impact viewed on a ‘Richter’ (logarithmic) scale   Weiss & McMichael, 2004 1 Viruses Infant/child ARI & diarrhoeal dis Log 1 0 10,000-fold difference in impact
Reemergence of Dengue   Environmental   Factors Climate change  Alteration  of  ecosystems Alteration of Geographical distribution of pathogens and vectors Increase in  vector-borne diseases Dengue Yellow Fever Ideal conditions for Dengue: Latitude :  35 0  north 35 0  south Altitude:   2,200 m Temperature:  15-40 °C Relative humidity:     high-moderate Changes in transmission Ecological changes Socio-economic changes
Sequential steps necessary for a mosquito to transmit an Arbovirus ,[object Object],[object Object],[object Object],[object Object],[object Object]
Paradigm ,[object Object],[object Object],[object Object],[object Object]
Population Growth Reemergence of Dengue   Socio-Economic Factors ,[object Object],[object Object],[object Object],[object Object],0 1,000,000,000 2,000,000,000 3,000,000,000 4,000,000,000 5,000,000,000 6,000,000,000 1830 1930 2000
Reemergence of Dengue   Uncontrolled Urbanization ,[object Object],[object Object],[object Object],[object Object],Sources:   Gubler, 1998; PAHO, 1997.
Source:  Vilas, 1995. Poverty
Reemergence of Dengue  Inadequate Environmental Management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Increase in breeding sites for the vector
Reemergence of Dengue     Population Movements ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Source:  OMT data. Traffic of microorganisms
—  continued and frequently unplanned urbanization; —  inadequate municipal services such as water supply and solid waste disposal; —  the escalating rate and geographical range of virus transmission brought about by intercontinental travel; —  the circulation of multiple strains and serotypes in one area; —  the adaptability of the vectors (Aedes aegypti and, to a lesser extent, Aedes albopictus mosquitoes); —  the unrestrained production and use of non-biodegradable food and drink packaging, and drums and other water storage vessels that often become larval habitats; —  the importation of used tyres by developing countries at risk for dengue; and —  non-existent, inconsistent, or fragmented national programmes The reasons for dengue’s emergence as a major global health problem have been well documented and include:
Receding – then Resurging? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Factors in Emerging/Re-emerging Infectious Diseases
[object Object],Social Communication Epidemiological Surveillance Entomology Patient Care Laboratory Integrated  Strategy Components
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Expected Results
[object Object],[object Object],[object Object],[object Object],Expected Results   cont.
[object Object],[object Object],[object Object],[object Object],Where are we going?
UNDIFFERENTIATED FEBRILE ILLNESS *  With Rash. * With Resp symp.   * Both   * With none. CLASSICAL DF BREAKBONE FEVER DHF DSS D  H  F. OR  DENGUE ILLNESSES.
UNDIFFERENTIATED FEBRILE ILLNESS . CLASSICAL DF DHF DSS OPD. HOSPITALIZATION ICU
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PERSONAL PROPHYLACTIC MEASURES- PREVENTION OF MOSQUITO BITES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
PREVENTION OF MULTIPLICATION OF MOSQUITO ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
TAKE LONG TERM MEASURES ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
URBAN BREEDING SITES
PROTECTION OF ELDERLY AND CHILDREN IS OF  VITAL IMPORTANCE
ELIMINATION OF  BREEDING SITES--- THE INITIATIVE  MOSTLY LIES WITH INDIVIDUALS

 ..And Before it is too late......... Fight The Bite......... .....Prevent Dengue.
[object Object],

 .. THANKS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Knowing is not enough; we must apply. Willing is not enough; we must do. (Goethe)

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Dengue

  • 1. Integrated Strategy for Dengue Prevention and Control
  • 2. The Global Impact of Dengue Virus Dengue Fever & Dengue Hemorrhagic Fever Endemic in more than 100 countries 50 million cases each year Areas infested with Aedes aegypti Areas with Aedes aegypti and dengue epidemic activity
  • 3. Examples of Emerging and Re-Emerging Infectious Disease: past 10 years A Fauci, NIAID/NIH, 2005
  • 4. 2 HIV Dengue H Papilloma v Ebola Hanta virus West Nile virus Tobacco Malaria Non- HIV tuberculosis Road accidents 3 5 6 Influenza Polio SARS vCJD Measles HBV + HCV 4 RSV, Rota virus 7 Hospital infection Suicide Major and minor killers: global impact viewed on a ‘Richter’ (logarithmic) scale Weiss & McMichael, 2004 1 Viruses Infant/child ARI & diarrhoeal dis Log 1 0 10,000-fold difference in impact
  • 5. Reemergence of Dengue Environmental Factors Climate change Alteration of ecosystems Alteration of Geographical distribution of pathogens and vectors Increase in vector-borne diseases Dengue Yellow Fever Ideal conditions for Dengue: Latitude : 35 0 north 35 0 south Altitude: 2,200 m Temperature: 15-40 °C Relative humidity: high-moderate Changes in transmission Ecological changes Socio-economic changes
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  • 10. Source: Vilas, 1995. Poverty
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  • 13. — continued and frequently unplanned urbanization; — inadequate municipal services such as water supply and solid waste disposal; — the escalating rate and geographical range of virus transmission brought about by intercontinental travel; — the circulation of multiple strains and serotypes in one area; — the adaptability of the vectors (Aedes aegypti and, to a lesser extent, Aedes albopictus mosquitoes); — the unrestrained production and use of non-biodegradable food and drink packaging, and drums and other water storage vessels that often become larval habitats; — the importation of used tyres by developing countries at risk for dengue; and — non-existent, inconsistent, or fragmented national programmes The reasons for dengue’s emergence as a major global health problem have been well documented and include:
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  • 20. UNDIFFERENTIATED FEBRILE ILLNESS * With Rash. * With Resp symp. * Both * With none. CLASSICAL DF BREAKBONE FEVER DHF DSS D H F. OR DENGUE ILLNESSES.
  • 21. UNDIFFERENTIATED FEBRILE ILLNESS . CLASSICAL DF DHF DSS OPD. HOSPITALIZATION ICU
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  • 29. PROTECTION OF ELDERLY AND CHILDREN IS OF VITAL IMPORTANCE
  • 30. ELIMINATION OF BREEDING SITES--- THE INITIATIVE MOSTLY LIES WITH INDIVIDUALS
  • 31. 
 ..And Before it is too late......... Fight The Bite......... .....Prevent Dengue.
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  • 33. Knowing is not enough; we must apply. Willing is not enough; we must do. (Goethe)

Hinweis der Redaktion

  1. Aedes Genus - not from around here Endemic in 100 countries - Africa, Americas, Eastern Mediterranean, SE Asia, Western Pacific Discuss difficulty with vaccine (exposure to 2 serotypes)