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1. Question by mavenofmusic: What drugs, other than Metfor
are used to treat Insulin Resistance?

2. I am slightly insulin resistant with normal blood sugars and
did not tolerate Metformin and my endocrinologist told
immediately. What other drugs are used to treat this conditi
aware diet and exercise are important components of treatin
have already incorporated that part of it into my li

3. Best answer:

4. Answer by Tin SIts a shame you can't tolerate Metformin.
around for insulin resistance. Your other choices are Act

5. The "glitazone" diabetes drugs Actos and Avandia may doub
of broken bones after a year or two of use

6. The finding comes from Swiss researchers who analyzed 12
U.K. diabetes patients. They compared the 1,020 patients w
kind of fracture to 3,728 matched patients who did not br

7. Related to diabetes diabetes symptoms, hypoglycem
diabetes, gestational diabetes, diabetes diet, type 1 diabete
, glucose, insulin resistance, diabetic neuropathy, A1c, exerc

8. © 2008 WebMD, Inc. All rights reserved.

9. Over the course of the study, most of the patients took sever
But those who refilled their Actos or Avandia prescriptions ei
- about 12 to 18 months of use -- had nearly twice the fract
patients.

10. And those who refilled their Actos or Avandia prescriptions 1
two or more years of treatment -- nearly tripled their risk o
Christophe R. Meier, PhD, head of pharmacoepidemiolo
University Hospital Basel, Switzerland, and colle

11. "We found a very strong signal here for higher risk of fracture
glitazones," Meier tells WebMD. "Our evidence fits together
models and clinical reports suggesting that these drugs ha
effect on bone. And we did not find any increased risk for
drugs, so all together, it looks like something really is go

12. (What does your doctor have to say about these risks? Talk
WebMD's Type 2 Diabetes Support Group message

13. Animal studies reported late last year strongly suggest that A
promote bone loss. Signs that women taking Avandia might b
of upper arm and hand fracture last year led the
manufacturer, GlaxoSmithKline, to voluntarily issue a letter
that Avandia might increase fracture risk.

14. Good luck

15. What do you think? Answer below!

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