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Biogenerics Follow-on-biologics Biobetters Biosuperiors                                                                     Early Bird
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                                                                                                            2nd Annual



        I                N              D                I                 A                          2               0               1              1
                  Navigating regulatory and R&D challenges and adopting the latest
              innovations to drive the successful commercialisation of Indian biosimilars
Two-Day Strategic Conference: 14-15 July 2011 Holiday Inn Mumbai International Airport, Mumbai, India




                                                                                                HEar outstanding
                                                                                               prEsEntations from:
    rEal-lifE casE studiEs on:                                                       KK Tripathi, Adviser, Scientist ‘G’ and Member Secretary RCGM
    4Regulatory Developments – understand the impact of local and                    department of Biotechnology
     international regulatory guidelines and the implications for your               Brij Patel, Deputy Manager, Biologicals and Biotechnology Unit
     biosimilars strategy                                                            medicines and Healthcare products regulatory agency
    4R&D and Process Development – gain in-depth guidance on                         (mHra)
     tackling complex R&D challenges to ensure the quality and safety of
     your biosimilars                                                                Roger L Williams, Chief Executive Officer, us pharmacopoeia
    4Commercialisation – evaluate different partnership models and                   KV Subramaniam, President and Chief Executive Officer
     outsourcing strategies to drive the early profitability of your                 reliance life sciences
     biosimilars business
                                                                                     Ganesh Kumraj, President Operations
    4Innovations – benefit from a showcase of the latest emerging                    Bharat serums and Vaccines
       technologies to reduce the timeframe and cost of your biosimilar
             product development                                                     Cyrus Karkaria, President Biotech Division
                                                                                     lupin pharmaceuticals
                                                                                     Dhananjay Patankar, Vice President Biologics
                                                                                     syngene international
     WHo sHould attEnd?                                                              Smita Singhania, Vice President and Head, Regulatory Affairs
      This conference has been designed specifically for VPs, Directors,             mabpharm
      GMs and Heads of: Biologics, Biotechnology, R&D, Process
      Development, Formulations, Analysis and Testing, Regulation, and               Rustom Mody, Chief Scientific Officer, intas Biopharmaceuticals
      Product Development from:                                                      Matthias Jöhnck , Head of Merck Millipore Chromatography
                                                                                     Research and Development, merck, darmstadt
      • Biopharma Manufacturers           • Equipment Suppliers
      • Biotechnology Manufacturers       • Ingredient and Material Suppliers        Anil Kukreja, Director Medical Affairs, roche products, india
      • Generic Pharma Manufacturers      • Analytical Laboratories
      • Innovator Pharma Manufacturers    • CRAMS                                    Mahua Ganguly, Head Medical Affairs, Biogen idec, india
                                                                                                                             Plus many more…

                                        Gold Partner                                                           Silver Partner




   In Association With                                              Media Partners                                                Organised By




  To register - Tel: +91 (022) 4046 1466 Fax: +91 (022) 4046 1477 Email: conferences-india@ubm.com
                                          www.biosimilars-india.com
ConfeRenCe Day one – ThuRsdAy 14 july 2011
08:30                   Registration and refreshments                                             13:30             Lunch and networking
09:00                   Opening remarks from the Chair                                            14:30             Regulation in practice: Navigating stringent European regulations
                                                                                                                    to successfully launch biosimilar drugs in EU markets
09:15                   Evaluating the potential role of India as a global leader in the                        •   Determining the key challenges met in gaining biosimilar regulatory
                        biosimilar market to leverage the opportunities available globally                          approval in Europe and devising strategies to surmount these




                                                                                                   Case study
                    •   Identifying the key drivers for the development of biosimilars and                      •   Clarifying the location criteria for undertaking clinical trials
 Keynote address




                        establishing India’s share of the market                                                •   Evaluating the level and type of data required to meet requirements
                    •   Determining India’s core strengths in biosimilars to underpin                           •   Overcoming the documentation complexities encountered when
                        the growth strategy                                                                         seeking European approval
                    •   Overcoming the impediments and obstacles hampering the growth of                        •   Summarising the lessons learnt to facilitate smooth approval for
                        biosimilars in India                                                                        Indian companies
                    •   Analysing the key action plan necessary to fast-track the                                   Ganesh Kumraj, President Operations
                        development of the Indian biosimilars market                                                Bharat Serums and Vaccines
                        KV Subramaniam, President and Chief Executive Officer
                        Reliance Life Sciences                                                    15:10             Clarifying the regulations specific to safety and efficacy for
                                                                                                                    biosimilar product development and identifying how these are
                                            Market Overview                                                         evolving with international standards
                                                                                                                •   Examining the scope of the evolving safety regulations and the
09:45                   Establishing the current size of the biosimilars market in India                            implications for biosimilar development in India
                        and forecasting opportunities for the longer term                                       •   Evaluating the potential of new processes and technologies in aiding
                    •   Understanding the current size and potential of biosimilars in India                        biosimilar safety compliance
                        and in regulated and semi-regulated markets                                             •   Identifying areas for improvement within pre-clinical and clinical
                    •   Evaluating the number of patents due to expire within the next                              trials to drive safety and efficacy
                        five years and determining the optimal time to capitalise on these                      •   Mapping out the latest safety guidelines for clinical trials
                        opportunities                                                                               when undertaken outside India
                    •   Comparing the Indian biosimilar market with global trends                                   Smita Singhania, Vice President and Head, Regulatory Affairs
                        and predicting the next steps and new opportunities                                         MabPharm
                    •   Examining how therapeutic areas are evolving to identify new uses
                        and opportunities for biosimilars                                         15:50             Afternoon refreshments and networking
                    •   Formulating a roadmap for success for the Indian biosimilars market
                        to minimise costs and maximise return on investment                                                           Market Opportunities
                        KV Anantharaman, Principal Analyst, Healthcare Research &
                        Analysis                                                                  16:20             Maximising the potential of strategic partnerships to enter the
                        Datamonitor                                                                                 biosimilar market
                                                                                                                •   Identifying the need for strategic partnerships in the biosimilars space
10:25                   Morning refreshments and networking                                                         to access markets and minimise the cost and risk involved
                                                                                                                •   Examining deals currently in place in the biosimilars market to
11:00                   Exploring the “dos and don’ts” of a biosimilar strategy –                                   understand the scope and commercial potential of partnerships and
                        examining the different real-life business models being used to                             the specific roles and responsibilities of partners
                                                                                                                •   Determining the appropriate partnership model to adopt – exploring
                        devise a roadmap for biosimilar success                                                     opportunities with research institutes, CROs and domestic and
                    •   Investigating how companies can successfully manufacture and                                international pharmaceutical companies
                        commercialise biosimilars and remain in the market for the long-term                    •   Establishing the key criteria for selecting a potential partner to drive
                    •   Evaluating the pros and cons of manufacturing biosimilar drugs for the                      progress in biosimilar product development
 Panel discussion




                        short-term and then implementing an exit strategy at the right price                    •   Aligning objectives to ensure a win-win scenario for all stakeholders
                    •   Applying lessons learnt from successes and failures in real-life                            Rahul Padhye, Head of Corporate Development
                        scenarios to maximise the business potential of biosimilars                                 Reliance Life Sciences
                    •   Identifying practical steps to strengthen the biosimilar market and
                        formulate a robust strategy for future development                        17:00           Investigating the latest trends in design and integrated concepts
                        KV Subramaniam, President and Chief Executive Officer                                     to ensure a cost-effective and efficient manufacturing process
                        Reliance Life Sciences                                                                    for biosimilars
                        Cyrus Karkaria, President Biotech Division                                              • Understanding the latest regulatory developments devised to drive
                        Lupin Pharmaceuticals                                                                     modernisation of the manufacturing facility
                        Dhananjay Patankar, Vice President Biologics                                            • Adopting the most up-to-date technology and equipment to
                        Syngene International                                                                     streamline the process and increase productivity and efficiency
                        Hareesh Parandhaman, Assistant Director Business Development                            • Upgrading facilities and implementing emerging single-use
                        Lupin Pharmaceuticals                                                                     techniques to enhance the production process and minimise costs
                                                                                                                  MS Mahadevan, Director, Strategic Marketing, Process Solutions
                                         Regulatory landscape                                                     Business Unit, Merck Millipore
12:30                   Defining the current regulatory position on biosimilars in India          17:40             Roundtable discussions: During this session the group will split into
                        to gain swift and smooth entry into the biopharmaceutical market                            a number of smaller discussion groups, each focused on a specific
                    •   Evaluating the regulatory structure and key bodies in place in India to                     theme arising from the day’s presentations, and led by one of the
                        support the development of the biosimilar industry                                          speakers of the day. This is the perfect opportunity for delegates to
                    •   Determining how the regulatory framework is evolving to ensure                              bring their live challenges to the table, and benefit from the combined
                        greater support and stimulation of the Indian biosimilar industry                           experiences and know-how of the roundtable leaders as well as fellow
                    •   Assessing the government incentives and initiatives currently in place                      delegates. Come armed with your most challenging questions and
                        and planned, around Indian biosimilars                                                      leave with a toolkit of practical implementable solutions.
                    •   Clarifying the regulatory requirements around clinical trials,
                        comparative analysis and documentation within India and when              18:30             Close of Conference Day One
                        exporting to international markets
                    •   Establishing the regulatory perspective on the future direction of the
                        Indian biosimilars market
                        KK Tripathi, Adviser, Scientist ‘G’ and Member Secretary RCGM
                        Department of Biotechnology                                                WHat dElEgatEs at Biosimilars india 2010 Had to say:


                                                                                                   “
13:00                   Understanding the US Pharmacopoeia perspective on                              The conference was useful in providing knowledge on


                                                                                                                                                                      ”
                        international regulatory models to predict and prepare for the
                        impact on the Indian market                                                regulatory guidelines and process development
                    •   Examining the role of US Pharmacopeia and the regulatory                                                  Mannan Khambati, Senior Manager, Bharat Serums and Vaccines
                        framework around biosimilars
                    •   Applying learnings, experiences and data requirements from the


                                                                                                   “
                        European model to the Indian market                                                     Perfect blend of the topics based in biosimilars. All the speakers


                                                                                                                                                                                           ”
                    •   Determining the probable shape of the regulatory guidelines for
                        biosimilars in the US when they are finalised                                           were well educated and experienced on the respective topics
                    •   Identifying and transferring key international findings from the                                                    Anita Ghagare, Senior Manager, Unichem Laboratories
                        evolving biosimilars regulatory landscape to drive progress
                        and growth in India
                        Video presentation: Roger L Williams, Chief Executive Officer
                        US Pharmacopoeia

To register - Tel: +91 (022) 4046 1466 Fax: +91 (022) 4046 1477 Email: conferences-india@ubm.com
ConfeRenCe Day Two – FRIdAy 15 july 2011
08:30 Registration and refreshments                                                                                              15:20 Showcasing emerging technologies in chromatography resin to
                                                                                                                                         increase the performance of different purification processes for
09:00 Opening remarks from the Chair                                                                                                     biomolecules
                                                                                                                                       • Evaluating traditional downstream processing technologies for
                                        Commercialisation in Practice                                                                    active pharmaceutical ingredients
                                                                                                                                       • Understanding the latest developments in chromatography resin for
09:10                  Benchmarking Indian biosimilar product development against                                                        effective purification of monoclonal antibodies and recombinant proteins
                       international companies to formulate a strategy for effective                                                   • Understanding the influence of resin surface modification technologies for
                       commercialisation and global business success                                                                     downstream processes
                   •   Comparing the quality and rate of product development to identify areas                                         • Identifying the new bead strategies to increase the performance in
                       for improvement and to focus expertise and investment                                                             different purification tasks
                   •   Streamlining processes and procedures to increase productivity and                                              • Overcoming challenges in these technologies and applying lessons learnt
                       reduce costs                                                                                                      Matthias Jöhnck, Head of Merck Millipore, Chromatography Research
                   •   Adopting the latest advancements in technology and techniques to drive                                            and Development, Merck, Darmstadt
                       product development and take biosimilars to the next level
                   •   Identifying the USP and exploiting this to gain market acceptance and                                     16:00               Examining the successful development of biosimilars for specific
                       achieve a competitive advantage in a highly populated market                                                                  therapeutic areas
                   •   Devising a robust marketing strategy to access markets and successfully
                       commercialise products                                                                                                        (a) Oncology – Navigating the regulatory requirements
                       Partha Ghosh, Director, Service Lead, Early Stage Development Europe,                                                           and guidelines for clinical trials to develop effective
                       Parexel Consulting                                                                                                              biosimilar drugs for oncology
                                                                                                                                                        • Understanding the relevant regulatory requirements to be met
09:50                  Evaluating the future market potential of biobetters in comparison                                                               • Evaluating the different types of comparability studies to be
                       to biosimilars to establish and capitalise on the opportunities in the                                                             undertaken to meet the innovator product characteristics
                       long-term                                                                                                                        • Determining the key criteria for clinical trials to establish the
                   •   Defining biobetters within the pharmaceutical market and how they are                                                              safety of the product
                       evolving to understand their full market size and potential                                                                      • Assessing the challenges of matching biosimilars to the
                   •   Clarifying the latest regulatory guidelines around biobetters                                                                      innovator product in terms of quality and characterisation
Panel discussion




                   •   Determining the impact of biopharmaceutical patent expiry on both                                                                • Identifying transferable learnings and conclusions to apply to the




                                                                                                                                      Case studies
                       biobetters and biosimilars                                                                                                      Indian market
                   •   Examining the commercial potential for biobetters and biosimilars within                                                           Anil Kukreja, Director Medical Affairs, Roche Products, India
                       the key biopharmaceutical areas of monoclonal antibodies, vaccines,
                       glycoproteins, blood factors and insulin                                                                                      (b) Neurology – Understanding the specific requirements
                   •   Ascertaining the extent to which biobetters or biosimilars could be the                                                           for the development of biologics and biosimilars
                       model for the future within the biopharmaceutical industry                                                                         and product improvement techniques in the field of
                       Brij Patel, Deputy Manager, Biologicals and Biotechnology Unit                                                                  neurology
                       Medicines and Healthcare products Regulatory Agency (MHRA)                                                                      • Determining the regulatory guidelines that must be adhered to
                       MK Sahib, Director Genomics and Biotechnology, Wockhardt                                                                        • Undertaking the necessary trials and tests to successfully
                       Rustom Mody, Chief Scientific Officer, Intas Biopharmaceuticals                                                                   achieve the characterisation of the biosimilar
                                                                                                                                                       • Transforming the manufacturing process through the latest
10:30 Morning refreshments and networking                                                                                                                equipment and facilities
                                                                                                                                                       • Developing the most appropriate and effective marketing
                                                   R&d Challenges                                                                                         strategies to successfully launch the product
                                                                                                                                                       • Identifying techniques and learnings that can be applied to
11:00                Overcoming the complexities involved in the cell                                                                                    biosimilar development for neurology in India
                     development process to increase the overall yield                                                                                   Mahua Ganguly, Head Medical Affairs, Biogen Idec, India
                   • Effectively identifying impurities and developing measures to minimise and
                     suppress viruses within cells                                                                               16:40               Closing remarks from the Chair
                   • Evaluating the various methods and technologies available to increase the
                     yield of the cell line                                                                                      17:00               Close of Conference Day Two
                   • Establishing robust techniques to tackle stability issues in biosimilars
                   • Redesigning the glycosylation process to make it more effective and
                     efficient
                     Laxmi S Rao, General Manager, Biotechnology Research Labs, USV
11:40                  Developing comparability packages to meet the global standard                                                Gold Partner
                       requirements for approvals of biologics                                                                      Thermo Scientific Cell Culture and
                   •   Understanding the guidelines available to support the comparability of                                       BioProcessing products deliver
                       biological products                                                                                          proven solutions to support upstream
                   •   Determining the data expectations surrounding non-clinical and clinical                                      and downstream applications. Our products portfolio and services are specifically
                       studies to establish comparability                                                                           designed to lend proven performance, improve your process efficiency, add flexibility
                   •   Developing strategies to address the challenges faced during the                                             and fast track product development. We are your reliable partner from early stage
                       development of comparability packages
                   •   Assessing the role of Quality by Design (QbD) in comparability                                               development to commercial production. From a single source, you can optimize
                       establishment studies                                                                                        production using our metabolic pathway design approach and augmented reality with
                       Mahesh Bhalgat, Vice President, Biological E                                                                 Single Use Solutions across your entire work flow. With a wealth of experience and
                                                                                                                                    knowledge behind every Thermo Scientific product, you are ensured that your Bio-
12:20 Lunch and networking                                                                                                          production process performs at its best.
13:30 Developing robust approaches to the effective characterisation of                                                             Silver Partner
        biosimilars at all stages of product development                                                                            GE Healthcare Life Sciences
      • Identifying different criteria which characterise a biosimilar product                                                      provides tools for drug discovery,
      • Incorporating measures around physical, chemical and biological properties
        into biosimilar comparability studies to effectively appraise similarity                                                    biopharmaceutical manufacturing and
      • Assessing the protein purity at all stages of development to identify and                                                   cellular technologies, so research
        remove any impurities cultivated during the process                                                                         scientists and specialists around the
      • Addressing the factors influencing immunogenicity to improve                                                                world can be more productive, effective
        development of the biosimilar drug                                                                                          and creative. Our vision is to be the start-to-finish bioprocessing solution provider, the
      • Ensuring that the same safety and efficacy levels are achieved with the                                                     partner of choice in cell and protein research, and the leader in life sciences services.
        biosimilar as the innovator drug to meet international quality standards                                                    Building on our broad expertise across life sciences, we are firmly committed to
        Rustom Mody, Chief Scientific Officer, Intas Biopharmaceuticals
                                                                                                                                    help researchers understand life at a molecular level and develop solutions that can
                                           Innovations in Biosimilars                                                               prevent, diagnose, treat, and cure disease. With our “healthymagination” initiative, we
                                                                                                                                    invite the world to join us on our journey as we continue to drive innovation focused on
14:10 Establishing the latest innovations in drug delivery systems for                                                              reducing costs, increasing access, and improving quality and efficiency in healthcare
        biosimilars to enhance the ultimate efficacy of the product
      • Outlining the regulatory guidelines for drug delivery systems such as
        injectables, oral and patches
      • Establishing the criteria for clinical trials and documentation required for
        these various delivery systems                                                                                              Promote your Business
      • Exploring the different platforms available for biosimilar drug delivery
        and the latest developments to maximise their potential in improving the                                                   Sponsoring or exhibiting at Biosimilars India 2011 is                          Exhibition Floor Plan


        product                                                                                                                    an excellent way to promote your business to a highly
      • Evaluating the specific challenges associated with the different platforms and                                             targeted group of key decision-makers with a specific                                  Coffee &
        leveraging the latest innovations to overcome these                                                                        interest in CRaMS, analytical labs, ingredients and                                   Lunch point
        Vinod Kuberkar, Head Contract Services                                                                                     materials. we have a range of business development
        Intas Biopharmaceuticals
                                                                                                                                   and marketing and sales solutions that will be tailored
14:50 Afternoon refreshments and networking                                                                                        to specifically deliver on your business objectives. To
                                                                                                                                   find out more about how you can make the most of your
                                                                                                                                   participation at this event, contact Cherwyn Martins
                                                                                                                                   sales Manager, on +91 (022) 6612 2692
                                                                                                                                   +91 98339 98003 or email cherwyn.martins@ubm.com
www.biosimilars-india.com
                            ©2011. UBM India Pvt. Ltd. This programme may change due to unforeseen circumstances. UBM India Pvt. Ltd. reserves the right to alter the venue and/or speakers.
Biogenerics Follow-on-biologics Biobetters Biosuperiors

                                                                                                      2nd Annual



                                           I       N          D        I        A                 2         0        1         1
                                               Navigating regulatory and R&D challenges and adopting the latest
                                           innovations to drive the successful commercialisation of Indian biosimilars
                                     Two-Day Strategic Conference: 14-15 July 2011 Holiday Inn Mumbai International Airport, Mumbai, India
                  Dear Colleague,

                  CPhI Conferences is delighted to bring you its 2nd Annual Biosimilars India 2011, an essential two-day conference. With
                  the Indian biosimilar market expected to grow to US$ 580 million by 2012, and new uses for biosimilars in new therapeutic
                  areas being developed daily, now is the time to take action and strategically position your company to capitalise on the host
                  of opportunities available.

                  But are you fully prepared to meet the unclear local and international regulatory requirements and cumbersome multiple
                  clearances surrounding biosimilars? Do you feel hindered by a lack of access to capital, demanding R&D challenges and
                  expensive manufacturing processes? Are you equipped to devise a robust strategy for successful commercialisation of
                  your biosimilar products? Attend Biosimilars India 2011 to gather implementable solutions and practical guidance to
                  tackle all of these challenges and more.

                  Building on the success of our 2010 event, we bring you a revised and refreshed agenda that deep-dives into the most
                  timely regulatory, R&D and commercial challenges facing the Indian biosimilars industry today.
                  Biosimilars India 2011 has been thoroughly researched with representatives from the local and international
                  pharmaceutical market to bring you two intensive days of practical insights, analyses, benchmarking and facilitated
                  networking.
                  Just some of the highlights of this year’s programme include opportunity to:
                             • Hear the Department of Biotechnology and US Pharmacopoeia define the current regulatory position on
                               biosimilars in India and determine the implications of international regulations for the Indian market

                             • Join Reliance Life Sciences as they evaluate the potential role of India as a global leader in the biosimilar
                               market

                             • Learn from Datamonitor the current size of the biosimilars market in India and forecast the growth
                               opportunities

                             • Benefit from a panel of experts including Lupin Pharmaceuticals, Syngene International and Reliance Life
                               Sciences exploring the “dos and don’ts” of a biosimilar strategy to ensure commercial success
                             • Investigate the latest innovations in biosimilars with Merck Millipore and Merck Darmstadt to identify
                               opportunities to streamline processes and reduce the costs of product development

                             • Hear from Intas Biopharmaceuticals on how to develop robust approaches to the effective characterisation
                               of biosimilars at all stages of product development

                             • Examine the successful development of biosimilars in practice through in-depth case study examples of their
                               therapeutic applications with Roche Products India and Biogen Idec India
                  Additional speakers from MabPharm, Bharat Serums and Vaccines, Wockhardt, USV, Biological E and Parexel
                  Consulting will also be sharing their unique experiences, unrivalled expertise and technical know-how with you.
                  Now is the time to take a step back and contemplate your biosimilar strategy. Take the reigns, ensure your place at this
                  high-level forum and position yourself at the cutting-edge of the latest trends and opportunities in the biosimilar market.

                  We look forward to welcoming you at what is sure to be a solution-packed two days.
                  Yours sincerely,




                  Oby George
                  Programme Manager
                  CPhI Conferences
                  P.S. The enclosed brochure contains the full list of in-depth topics and outstanding speaker line-up. To secure your place at
                  a discounted price, please visit www.biosimilars-india.com, email conferences-india@ubm.com, call us on
                  +91 (022) 4046 1466, or complete and return to us the booking form in the conference brochure.


7 Great Reasons to Attend
Regulatory guidance – hear the latest regulatory developments around biosimilars and gain in-depth insights from key regulators, including DBT and US Pharmacopoeia and
their plans to support the biosimilar industry
Revised and refreshed agenda for 2011 – based on extensive research with past delegates and key representatives from the biopharmaceutical industry, the 2011 agenda
will tackle all of your most current challenges
Real-life case studies – benefit from practical insights from the leading practitioners such as Intas, Reliance Life Sciences, Merck and many others
Implementable technical solutions – tackle your most complex and expensive R&D challenges and streamline your manufacturing processes
Commercialisation strategies – learn from the experts how to enter new markets, how long to remain in the biosimilar market and how to formulate a strategy to achieve
commercial viability and business success
Extended networking – take advantage of a host of facilitated networking opportunities specifically designed to drive new business opportunities
Frequent Q&A sessions – put your most pressing concerns and queries to the experts and get your business-critical questions answered
2nd Annual                                                                              Ways to Register
                                                                                                                                                                Online:         www.biosimilars-india.com
                                                                                                                                                                Tel             +91 (022) 4046 1466
                                                                                                                                                                Fax             +91 (022) 4046 1477
     I         N          D          I         A                    2          0          1          1
                                                                                                                                                                Email           conferences-india@ubm.com
    Two-Day Strategic Conference                                                                                                                                Post            Conference Department,
    14-15 July 2011                                                                                                                                                             UBM India Pvt Ltd, Sagar Tech Plaza A, 615-617,
    Holiday Inn Mumbai International Airport                                                                                                                                    6th Floor, Andheri Kurla Road, Saki Naka Junction,
    Mumbai                                                                                                                                                                      Andheri East, Mumbai, 400072, India
    India

                                                                                                         Indian Delegate @ INR 35,000 + 10.3% Service Tax = INR 38,605
   Book and pay before Friday 17 June 2011                                                               International Delegate US$ 1,295 + 10.3% Service Tax = US$ 1,428.39
                                                                                                         Indian Delegate @ INR 40,000 + 10.3% Service Tax = INR 44,120
   Standard Price                                                                                        International Delegate US$ 1,395 + 10.3% Service Tax = US$ 1,538.69


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  15 days post the conference.                                                                                              hotels at discounted event rates. These rates are held for a limited amount of time, so please book early to avoid
• Conference fees include entrance to the conference sessions, refreshments as per onsite schedule, and the                 disappointment. Call +91 (0)22 2410 2801/2/3 or email miceindia@orbit-elite.com
  conference papers. Please note that accommodation and travel are not included in the conference fee.                       Programme Changes:
• Fees are subject to applicable taxes as per government rules and regulations.                                           • Please note that speakers and topics were confirmed at the time of publishing; however, it may be necessary
  Pricing and Discounts:                                                                                                    due to unforeseen circumstances to alter the content, timing, speakers or venue. UBM reserves the right to alter or
• To be eligible for an Early Bird discount, the signed booking form must be received by close of business on               modify the advertised speakers and/or topics if necessary.
  the relevant deadline date, with full payment received no later than 5 working days following date of invoice.          • Any substitutions or alterations will be updated on the event website as soon as possible.
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  apply and the current rate at that time will be applicable.                                                             • By entering your details in the fields above, you agree to allow UBM India Pvt Ltd. and companies associated with
• A group booking discount of 5% is applicable to bookings of 3 or more delegates and 10% to 5 or more delegates.           the event to contact you (by post, telephone, sms, email or fax) regarding relevant products or services provided.
  Group booking discounts only apply if all delegates in the group book and pay at the same time.                           If at any time you do not wish to receive anything from UBM India Pvt Ltd. or carefully selected 3rd parties,
  Cancellation and Substitutions:                                                                                           please write to Manoj Ambardekar, Database Manager, UBM India Pvt Ltd. Sagar Tech Plaza A, 119, 1st Floor,
• Once booked cancellation of delegate places cannot be made, however a substitution can be made at any time.               Andheri Kurla Road, Saki Naka Junction, Andheri East, Mumbai, 400072, India, or email manoj.ambardekar@ubm.com.
  Please email details of the substitute delegate to conferences@ubmindia.com at the earliest opportunity.                  This contract is subject to Mumbai Jurisdiction law.
• In the event that UBM cancels an event for any reason, you will receive a refund for 100% of the conference fee paid.
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                                                                                                                            Service Tax Registered No. AAACU8181DST001
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  another UBM event to be mutually agreed with UBM, which must occur within one year from the date of                        Customer Code: Web
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Broucher

  • 1. Biogenerics Follow-on-biologics Biobetters Biosuperiors Early Bird discounts! Book before Friday 17 June 2011 to save INR 5,000/ US$ 100 2nd Annual I N D I A 2 0 1 1 Navigating regulatory and R&D challenges and adopting the latest innovations to drive the successful commercialisation of Indian biosimilars Two-Day Strategic Conference: 14-15 July 2011 Holiday Inn Mumbai International Airport, Mumbai, India HEar outstanding prEsEntations from: rEal-lifE casE studiEs on: KK Tripathi, Adviser, Scientist ‘G’ and Member Secretary RCGM 4Regulatory Developments – understand the impact of local and department of Biotechnology international regulatory guidelines and the implications for your Brij Patel, Deputy Manager, Biologicals and Biotechnology Unit biosimilars strategy medicines and Healthcare products regulatory agency 4R&D and Process Development – gain in-depth guidance on (mHra) tackling complex R&D challenges to ensure the quality and safety of your biosimilars Roger L Williams, Chief Executive Officer, us pharmacopoeia 4Commercialisation – evaluate different partnership models and KV Subramaniam, President and Chief Executive Officer outsourcing strategies to drive the early profitability of your reliance life sciences biosimilars business Ganesh Kumraj, President Operations 4Innovations – benefit from a showcase of the latest emerging Bharat serums and Vaccines technologies to reduce the timeframe and cost of your biosimilar product development Cyrus Karkaria, President Biotech Division lupin pharmaceuticals Dhananjay Patankar, Vice President Biologics syngene international WHo sHould attEnd? Smita Singhania, Vice President and Head, Regulatory Affairs This conference has been designed specifically for VPs, Directors, mabpharm GMs and Heads of: Biologics, Biotechnology, R&D, Process Development, Formulations, Analysis and Testing, Regulation, and Rustom Mody, Chief Scientific Officer, intas Biopharmaceuticals Product Development from: Matthias Jöhnck , Head of Merck Millipore Chromatography Research and Development, merck, darmstadt • Biopharma Manufacturers • Equipment Suppliers • Biotechnology Manufacturers • Ingredient and Material Suppliers Anil Kukreja, Director Medical Affairs, roche products, india • Generic Pharma Manufacturers • Analytical Laboratories • Innovator Pharma Manufacturers • CRAMS Mahua Ganguly, Head Medical Affairs, Biogen idec, india Plus many more… Gold Partner Silver Partner In Association With Media Partners Organised By To register - Tel: +91 (022) 4046 1466 Fax: +91 (022) 4046 1477 Email: conferences-india@ubm.com www.biosimilars-india.com
  • 2. ConfeRenCe Day one – ThuRsdAy 14 july 2011 08:30 Registration and refreshments 13:30 Lunch and networking 09:00 Opening remarks from the Chair 14:30 Regulation in practice: Navigating stringent European regulations to successfully launch biosimilar drugs in EU markets 09:15 Evaluating the potential role of India as a global leader in the • Determining the key challenges met in gaining biosimilar regulatory biosimilar market to leverage the opportunities available globally approval in Europe and devising strategies to surmount these Case study • Identifying the key drivers for the development of biosimilars and • Clarifying the location criteria for undertaking clinical trials Keynote address establishing India’s share of the market • Evaluating the level and type of data required to meet requirements • Determining India’s core strengths in biosimilars to underpin • Overcoming the documentation complexities encountered when the growth strategy seeking European approval • Overcoming the impediments and obstacles hampering the growth of • Summarising the lessons learnt to facilitate smooth approval for biosimilars in India Indian companies • Analysing the key action plan necessary to fast-track the Ganesh Kumraj, President Operations development of the Indian biosimilars market Bharat Serums and Vaccines KV Subramaniam, President and Chief Executive Officer Reliance Life Sciences 15:10 Clarifying the regulations specific to safety and efficacy for biosimilar product development and identifying how these are Market Overview evolving with international standards • Examining the scope of the evolving safety regulations and the 09:45 Establishing the current size of the biosimilars market in India implications for biosimilar development in India and forecasting opportunities for the longer term • Evaluating the potential of new processes and technologies in aiding • Understanding the current size and potential of biosimilars in India biosimilar safety compliance and in regulated and semi-regulated markets • Identifying areas for improvement within pre-clinical and clinical • Evaluating the number of patents due to expire within the next trials to drive safety and efficacy five years and determining the optimal time to capitalise on these • Mapping out the latest safety guidelines for clinical trials opportunities when undertaken outside India • Comparing the Indian biosimilar market with global trends Smita Singhania, Vice President and Head, Regulatory Affairs and predicting the next steps and new opportunities MabPharm • Examining how therapeutic areas are evolving to identify new uses and opportunities for biosimilars 15:50 Afternoon refreshments and networking • Formulating a roadmap for success for the Indian biosimilars market to minimise costs and maximise return on investment Market Opportunities KV Anantharaman, Principal Analyst, Healthcare Research & Analysis 16:20 Maximising the potential of strategic partnerships to enter the Datamonitor biosimilar market • Identifying the need for strategic partnerships in the biosimilars space 10:25 Morning refreshments and networking to access markets and minimise the cost and risk involved • Examining deals currently in place in the biosimilars market to 11:00 Exploring the “dos and don’ts” of a biosimilar strategy – understand the scope and commercial potential of partnerships and examining the different real-life business models being used to the specific roles and responsibilities of partners • Determining the appropriate partnership model to adopt – exploring devise a roadmap for biosimilar success opportunities with research institutes, CROs and domestic and • Investigating how companies can successfully manufacture and international pharmaceutical companies commercialise biosimilars and remain in the market for the long-term • Establishing the key criteria for selecting a potential partner to drive • Evaluating the pros and cons of manufacturing biosimilar drugs for the progress in biosimilar product development Panel discussion short-term and then implementing an exit strategy at the right price • Aligning objectives to ensure a win-win scenario for all stakeholders • Applying lessons learnt from successes and failures in real-life Rahul Padhye, Head of Corporate Development scenarios to maximise the business potential of biosimilars Reliance Life Sciences • Identifying practical steps to strengthen the biosimilar market and formulate a robust strategy for future development 17:00 Investigating the latest trends in design and integrated concepts KV Subramaniam, President and Chief Executive Officer to ensure a cost-effective and efficient manufacturing process Reliance Life Sciences for biosimilars Cyrus Karkaria, President Biotech Division • Understanding the latest regulatory developments devised to drive Lupin Pharmaceuticals modernisation of the manufacturing facility Dhananjay Patankar, Vice President Biologics • Adopting the most up-to-date technology and equipment to Syngene International streamline the process and increase productivity and efficiency Hareesh Parandhaman, Assistant Director Business Development • Upgrading facilities and implementing emerging single-use Lupin Pharmaceuticals techniques to enhance the production process and minimise costs MS Mahadevan, Director, Strategic Marketing, Process Solutions Regulatory landscape Business Unit, Merck Millipore 12:30 Defining the current regulatory position on biosimilars in India 17:40 Roundtable discussions: During this session the group will split into to gain swift and smooth entry into the biopharmaceutical market a number of smaller discussion groups, each focused on a specific • Evaluating the regulatory structure and key bodies in place in India to theme arising from the day’s presentations, and led by one of the support the development of the biosimilar industry speakers of the day. This is the perfect opportunity for delegates to • Determining how the regulatory framework is evolving to ensure bring their live challenges to the table, and benefit from the combined greater support and stimulation of the Indian biosimilar industry experiences and know-how of the roundtable leaders as well as fellow • Assessing the government incentives and initiatives currently in place delegates. Come armed with your most challenging questions and and planned, around Indian biosimilars leave with a toolkit of practical implementable solutions. • Clarifying the regulatory requirements around clinical trials, comparative analysis and documentation within India and when 18:30 Close of Conference Day One exporting to international markets • Establishing the regulatory perspective on the future direction of the Indian biosimilars market KK Tripathi, Adviser, Scientist ‘G’ and Member Secretary RCGM Department of Biotechnology WHat dElEgatEs at Biosimilars india 2010 Had to say: “ 13:00 Understanding the US Pharmacopoeia perspective on The conference was useful in providing knowledge on ” international regulatory models to predict and prepare for the impact on the Indian market regulatory guidelines and process development • Examining the role of US Pharmacopeia and the regulatory Mannan Khambati, Senior Manager, Bharat Serums and Vaccines framework around biosimilars • Applying learnings, experiences and data requirements from the “ European model to the Indian market Perfect blend of the topics based in biosimilars. All the speakers ” • Determining the probable shape of the regulatory guidelines for biosimilars in the US when they are finalised were well educated and experienced on the respective topics • Identifying and transferring key international findings from the Anita Ghagare, Senior Manager, Unichem Laboratories evolving biosimilars regulatory landscape to drive progress and growth in India Video presentation: Roger L Williams, Chief Executive Officer US Pharmacopoeia To register - Tel: +91 (022) 4046 1466 Fax: +91 (022) 4046 1477 Email: conferences-india@ubm.com
  • 3. ConfeRenCe Day Two – FRIdAy 15 july 2011 08:30 Registration and refreshments 15:20 Showcasing emerging technologies in chromatography resin to increase the performance of different purification processes for 09:00 Opening remarks from the Chair biomolecules • Evaluating traditional downstream processing technologies for Commercialisation in Practice active pharmaceutical ingredients • Understanding the latest developments in chromatography resin for 09:10 Benchmarking Indian biosimilar product development against effective purification of monoclonal antibodies and recombinant proteins international companies to formulate a strategy for effective • Understanding the influence of resin surface modification technologies for commercialisation and global business success downstream processes • Comparing the quality and rate of product development to identify areas • Identifying the new bead strategies to increase the performance in for improvement and to focus expertise and investment different purification tasks • Streamlining processes and procedures to increase productivity and • Overcoming challenges in these technologies and applying lessons learnt reduce costs Matthias Jöhnck, Head of Merck Millipore, Chromatography Research • Adopting the latest advancements in technology and techniques to drive and Development, Merck, Darmstadt product development and take biosimilars to the next level • Identifying the USP and exploiting this to gain market acceptance and 16:00 Examining the successful development of biosimilars for specific achieve a competitive advantage in a highly populated market therapeutic areas • Devising a robust marketing strategy to access markets and successfully commercialise products (a) Oncology – Navigating the regulatory requirements Partha Ghosh, Director, Service Lead, Early Stage Development Europe, and guidelines for clinical trials to develop effective Parexel Consulting biosimilar drugs for oncology • Understanding the relevant regulatory requirements to be met 09:50 Evaluating the future market potential of biobetters in comparison • Evaluating the different types of comparability studies to be to biosimilars to establish and capitalise on the opportunities in the undertaken to meet the innovator product characteristics long-term • Determining the key criteria for clinical trials to establish the • Defining biobetters within the pharmaceutical market and how they are safety of the product evolving to understand their full market size and potential • Assessing the challenges of matching biosimilars to the • Clarifying the latest regulatory guidelines around biobetters innovator product in terms of quality and characterisation Panel discussion • Determining the impact of biopharmaceutical patent expiry on both • Identifying transferable learnings and conclusions to apply to the Case studies biobetters and biosimilars Indian market • Examining the commercial potential for biobetters and biosimilars within Anil Kukreja, Director Medical Affairs, Roche Products, India the key biopharmaceutical areas of monoclonal antibodies, vaccines, glycoproteins, blood factors and insulin (b) Neurology – Understanding the specific requirements • Ascertaining the extent to which biobetters or biosimilars could be the for the development of biologics and biosimilars model for the future within the biopharmaceutical industry and product improvement techniques in the field of Brij Patel, Deputy Manager, Biologicals and Biotechnology Unit neurology Medicines and Healthcare products Regulatory Agency (MHRA) • Determining the regulatory guidelines that must be adhered to MK Sahib, Director Genomics and Biotechnology, Wockhardt • Undertaking the necessary trials and tests to successfully Rustom Mody, Chief Scientific Officer, Intas Biopharmaceuticals achieve the characterisation of the biosimilar • Transforming the manufacturing process through the latest 10:30 Morning refreshments and networking equipment and facilities • Developing the most appropriate and effective marketing R&d Challenges strategies to successfully launch the product • Identifying techniques and learnings that can be applied to 11:00 Overcoming the complexities involved in the cell biosimilar development for neurology in India development process to increase the overall yield Mahua Ganguly, Head Medical Affairs, Biogen Idec, India • Effectively identifying impurities and developing measures to minimise and suppress viruses within cells 16:40 Closing remarks from the Chair • Evaluating the various methods and technologies available to increase the yield of the cell line 17:00 Close of Conference Day Two • Establishing robust techniques to tackle stability issues in biosimilars • Redesigning the glycosylation process to make it more effective and efficient Laxmi S Rao, General Manager, Biotechnology Research Labs, USV 11:40 Developing comparability packages to meet the global standard Gold Partner requirements for approvals of biologics Thermo Scientific Cell Culture and • Understanding the guidelines available to support the comparability of BioProcessing products deliver biological products proven solutions to support upstream • Determining the data expectations surrounding non-clinical and clinical and downstream applications. Our products portfolio and services are specifically studies to establish comparability designed to lend proven performance, improve your process efficiency, add flexibility • Developing strategies to address the challenges faced during the and fast track product development. We are your reliable partner from early stage development of comparability packages • Assessing the role of Quality by Design (QbD) in comparability development to commercial production. From a single source, you can optimize establishment studies production using our metabolic pathway design approach and augmented reality with Mahesh Bhalgat, Vice President, Biological E Single Use Solutions across your entire work flow. With a wealth of experience and knowledge behind every Thermo Scientific product, you are ensured that your Bio- 12:20 Lunch and networking production process performs at its best. 13:30 Developing robust approaches to the effective characterisation of Silver Partner biosimilars at all stages of product development GE Healthcare Life Sciences • Identifying different criteria which characterise a biosimilar product provides tools for drug discovery, • Incorporating measures around physical, chemical and biological properties into biosimilar comparability studies to effectively appraise similarity biopharmaceutical manufacturing and • Assessing the protein purity at all stages of development to identify and cellular technologies, so research remove any impurities cultivated during the process scientists and specialists around the • Addressing the factors influencing immunogenicity to improve world can be more productive, effective development of the biosimilar drug and creative. Our vision is to be the start-to-finish bioprocessing solution provider, the • Ensuring that the same safety and efficacy levels are achieved with the partner of choice in cell and protein research, and the leader in life sciences services. biosimilar as the innovator drug to meet international quality standards Building on our broad expertise across life sciences, we are firmly committed to Rustom Mody, Chief Scientific Officer, Intas Biopharmaceuticals help researchers understand life at a molecular level and develop solutions that can Innovations in Biosimilars prevent, diagnose, treat, and cure disease. With our “healthymagination” initiative, we invite the world to join us on our journey as we continue to drive innovation focused on 14:10 Establishing the latest innovations in drug delivery systems for reducing costs, increasing access, and improving quality and efficiency in healthcare biosimilars to enhance the ultimate efficacy of the product • Outlining the regulatory guidelines for drug delivery systems such as injectables, oral and patches • Establishing the criteria for clinical trials and documentation required for these various delivery systems Promote your Business • Exploring the different platforms available for biosimilar drug delivery and the latest developments to maximise their potential in improving the Sponsoring or exhibiting at Biosimilars India 2011 is Exhibition Floor Plan product an excellent way to promote your business to a highly • Evaluating the specific challenges associated with the different platforms and targeted group of key decision-makers with a specific Coffee & leveraging the latest innovations to overcome these interest in CRaMS, analytical labs, ingredients and Lunch point Vinod Kuberkar, Head Contract Services materials. we have a range of business development Intas Biopharmaceuticals and marketing and sales solutions that will be tailored 14:50 Afternoon refreshments and networking to specifically deliver on your business objectives. To find out more about how you can make the most of your participation at this event, contact Cherwyn Martins sales Manager, on +91 (022) 6612 2692 +91 98339 98003 or email cherwyn.martins@ubm.com www.biosimilars-india.com ©2011. UBM India Pvt. Ltd. This programme may change due to unforeseen circumstances. UBM India Pvt. Ltd. reserves the right to alter the venue and/or speakers.
  • 4. Biogenerics Follow-on-biologics Biobetters Biosuperiors 2nd Annual I N D I A 2 0 1 1 Navigating regulatory and R&D challenges and adopting the latest innovations to drive the successful commercialisation of Indian biosimilars Two-Day Strategic Conference: 14-15 July 2011 Holiday Inn Mumbai International Airport, Mumbai, India Dear Colleague, CPhI Conferences is delighted to bring you its 2nd Annual Biosimilars India 2011, an essential two-day conference. With the Indian biosimilar market expected to grow to US$ 580 million by 2012, and new uses for biosimilars in new therapeutic areas being developed daily, now is the time to take action and strategically position your company to capitalise on the host of opportunities available. But are you fully prepared to meet the unclear local and international regulatory requirements and cumbersome multiple clearances surrounding biosimilars? Do you feel hindered by a lack of access to capital, demanding R&D challenges and expensive manufacturing processes? Are you equipped to devise a robust strategy for successful commercialisation of your biosimilar products? Attend Biosimilars India 2011 to gather implementable solutions and practical guidance to tackle all of these challenges and more. Building on the success of our 2010 event, we bring you a revised and refreshed agenda that deep-dives into the most timely regulatory, R&D and commercial challenges facing the Indian biosimilars industry today. Biosimilars India 2011 has been thoroughly researched with representatives from the local and international pharmaceutical market to bring you two intensive days of practical insights, analyses, benchmarking and facilitated networking. Just some of the highlights of this year’s programme include opportunity to: • Hear the Department of Biotechnology and US Pharmacopoeia define the current regulatory position on biosimilars in India and determine the implications of international regulations for the Indian market • Join Reliance Life Sciences as they evaluate the potential role of India as a global leader in the biosimilar market • Learn from Datamonitor the current size of the biosimilars market in India and forecast the growth opportunities • Benefit from a panel of experts including Lupin Pharmaceuticals, Syngene International and Reliance Life Sciences exploring the “dos and don’ts” of a biosimilar strategy to ensure commercial success • Investigate the latest innovations in biosimilars with Merck Millipore and Merck Darmstadt to identify opportunities to streamline processes and reduce the costs of product development • Hear from Intas Biopharmaceuticals on how to develop robust approaches to the effective characterisation of biosimilars at all stages of product development • Examine the successful development of biosimilars in practice through in-depth case study examples of their therapeutic applications with Roche Products India and Biogen Idec India Additional speakers from MabPharm, Bharat Serums and Vaccines, Wockhardt, USV, Biological E and Parexel Consulting will also be sharing their unique experiences, unrivalled expertise and technical know-how with you. Now is the time to take a step back and contemplate your biosimilar strategy. Take the reigns, ensure your place at this high-level forum and position yourself at the cutting-edge of the latest trends and opportunities in the biosimilar market. We look forward to welcoming you at what is sure to be a solution-packed two days. Yours sincerely, Oby George Programme Manager CPhI Conferences P.S. The enclosed brochure contains the full list of in-depth topics and outstanding speaker line-up. To secure your place at a discounted price, please visit www.biosimilars-india.com, email conferences-india@ubm.com, call us on +91 (022) 4046 1466, or complete and return to us the booking form in the conference brochure. 7 Great Reasons to Attend Regulatory guidance – hear the latest regulatory developments around biosimilars and gain in-depth insights from key regulators, including DBT and US Pharmacopoeia and their plans to support the biosimilar industry Revised and refreshed agenda for 2011 – based on extensive research with past delegates and key representatives from the biopharmaceutical industry, the 2011 agenda will tackle all of your most current challenges Real-life case studies – benefit from practical insights from the leading practitioners such as Intas, Reliance Life Sciences, Merck and many others Implementable technical solutions – tackle your most complex and expensive R&D challenges and streamline your manufacturing processes Commercialisation strategies – learn from the experts how to enter new markets, how long to remain in the biosimilar market and how to formulate a strategy to achieve commercial viability and business success Extended networking – take advantage of a host of facilitated networking opportunities specifically designed to drive new business opportunities Frequent Q&A sessions – put your most pressing concerns and queries to the experts and get your business-critical questions answered
  • 5. 2nd Annual Ways to Register Online: www.biosimilars-india.com Tel +91 (022) 4046 1466 Fax +91 (022) 4046 1477 I N D I A 2 0 1 1 Email conferences-india@ubm.com Two-Day Strategic Conference Post Conference Department, 14-15 July 2011 UBM India Pvt Ltd, Sagar Tech Plaza A, 615-617, Holiday Inn Mumbai International Airport 6th Floor, Andheri Kurla Road, Saki Naka Junction, Mumbai Andheri East, Mumbai, 400072, India India Indian Delegate @ INR 35,000 + 10.3% Service Tax = INR 38,605 Book and pay before Friday 17 June 2011 International Delegate US$ 1,295 + 10.3% Service Tax = US$ 1,428.39 Indian Delegate @ INR 40,000 + 10.3% Service Tax = INR 44,120 Standard Price International Delegate US$ 1,395 + 10.3% Service Tax = US$ 1,538.69 Title: First Name: Surname: Company Name: Job Title: Department: Address: Tel: Fax: Email: By providing your email address you consent to being contacted by email for direct marketing purposes by UBM India Pvt. 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