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PALPITATIONS




      Dr POLAMURI TABITHA
           PG FIRST YR
DEFINITION

   Uncomfortable awareness of heart beat
    or undue awareness of heart action.

   Defined as thumping , pounding or
    fluttering sensation in the chest.

   This sensation can be either intermittent
    or sustained and either regular or
    irregular
   Most patients interpret palpitations as
    unusual awareness of the heart beat
    and become concerned when they
    sense that they had skipped or
    missing heartbeats.

   They are often noted when the patient
    is quietly resting , during which time
    other stimuli are minimal.
PHYSIOLOGY
Palpitation is due to

 Alteration in heart rate
        Eg: sinus tachycardia &
  bradycardia
 Alteration in heart rhythm
       Eg: Atrial fibrillation
 Augmentation of myocardial
  contraction
        Eg: anxiety states & drugs
NATURE OF PALPITATIONS
FEATURE                           SUGGESTS

HEART MISSES AND THUMPS           ECTOPIC BEATS

WORSE AT REST                     ECTOPIC BEATS


VERY FAST REGULAR                 SVT / VT

SUDDEN ONSET                      SVT / VT

OFFSET WITH VAGAL MANOEUVRES      SVT

FAST AND IRREGULAR                AF and ATRIAL FLUTTER with varying
                                  block
FORCEFUL AND REGULAR – NOT FAST   AWARENESS OF SINUS RHYTHM
                                  (ANXIETY)
SEVERE DIZZINESS OR SYNCOPE       VT or BRADYARRHYTHMIAS

PRE-EXISTING HEART FAILURE        VT
CAUSES OF PALPITATIONS


      CARDIAC       PSYCHIATRI
                        C
        43%            31%




     MISCELLANEOU   UNKNOWN
           S
          10%         16%
Cardiovascular Causes
Arrhythmias
 Premature atrial and ventricular
  contractions
 Supraventicular and ventricular
  arrhythmias
 WPW syndrome
 Atrial fibrillation
 Atrial flutter with varying block
 Brady-arrhythmias : complete heart block
 Sick-sinus syndrome
Non-arrhythmic cardiac
causes
 Mitral valve prolapse (with or without
  associated arrhythmias)
 Aortic insufficiency
 Atrial myxoma
 Pulmonary embolism
 Congenital heart ds
 Systemic hypertension
 Pericarditis
 Pacemaker induced tachycardia
Psychiatric Causes
 Panic attacks
 Anxiety states
 Somatization


Patients with psychiatric causes for
 palpitations more commonly report a
 longer duration of sensation >15min &
 multiplicity of symptoms than do
 patients with other causes
   The physician must remember that
    panic disorder and significant
    arrhythmias are not mutually exclusive,
    and that cardiac evaluation still may be
    necessary in patients with suspected
    panic disorder.

   Arrhythmic causes must be ruled out
    before the diagnosis of anxiety or panic
    disorder can be accepted as the cause
    of the palpitations.
Miscellaneous Causes
 Hyperkinetic circulatory states :
        Anaemia , Fever , Thyrotoxicosis ,
  Hypoglycemia , Phaechromocytoma
 Drugs :
        Aminophylline , Atropine , Thyroxine
  , Tricyclic antidepressants , Vasodilators
  , Digitalis
 Others :
        Caffeine , Cocaine , Amphetamines
  , Tobacco , Ethanol
 Spontaneous skeletal muscle
  contractions of the chest wall
 Systemic mastocytosis
 Physiological : exertion , excitement ,
  pregnancy
 Neurocirculatory asthenia or Da
  costa’s syndrome or Effort syndrome
  or Soldier’s heart
 Vaso-vagal attack
APPROACH TO THE PATIENT WITH
PALPITATIONS



    “Principal goal in assessing patients with
      palpitations is to determine if the
      symptom is caused by a life threatening
      arrhythmia”
History
“Patients with coronary artery disease
  or risk factors for CAD are at greater
  risk for ventricular arrhythmias as a
  cause for palpitations”

In addition , the association of
 palpitations with other symptoms
 suggesting haemodynamic
 compromise including syncope or
 lightheadedness supports this
 diagnosis
Remember


“All palpitations are not arrhythmias and
  many arrhythmias do not palpitate”
HOW TO EVALUATE
        PALPITATION
STEP 1
 Is palpitation continuous or intermittent ?
             Intermittent P. are commonly
  caused by premature atrial or ventricular
  contractions : the post extrasystolic beat
  is sensed by the patient owing to the
  increase in ventricular end-diastolic
  dimension following the pause in the
  cardiac cycle and the increased strength
  of contraction (post-extrasystolic
  potentiation)
STEP 2

Is heart beat regular or irregular ?

   Regular , sustained palpitations can
    be caused by SVT and VT

   Irregular , sustained palpitations can
    be caused by Atrial fibrillation
   STEP 3 : What is the ~ heart rate ?

   STEP 4 : Does palpitations occur in
    discrete attacks ?
        Is onset abrupt?
        How do attacks terminate?
    -Ventricular arrhythmias are of sudden
    onset
    -Holding breath or vagal manoeuvres
    decrease palpitations in SVT
STEP 5
Are there any associated symptoms ?

   Chest pain : Arrhythmogenic MI
   Dyspnoea : Heart failure due to
    arrhythmias
   Syncope : low cardiac output during
    arrhythmias , hypoglycemia ,
    phaechromocytoma
   Polyuria : SVT
   Sweating : Anxiety ,hypoglycemia
   Diarrhoea : Thyrotoxicosis
STEP 6 :
 Are there any precipitating factors ?
       exercise , stress (hyperdynamic
  cardiovascular states caused by
  catecholaminergic stimulation)
       alcohol intake , drugs
STEP 7 :
 Is there a history of structural heart
  disease ?
       coronary heart ds , valvular heart ds
“It is often useful either to ask the
  patient to tap out the rhythm of the
  palpitations or to take his / her pulse
  while experiencing palpitations”
Palpitations that are positional

    generally reflect a structural process
    within heart
    Eg : Atrial myxoma

    or adjacent to the heart
    Eg : Mediastinal mass
SIMPLE APPROACH TO DIAGNOSIS OF
          PALPITATION

                         Is heart beat
                           regular ?




                YES
                                                     NO
  Are there any discrete attacks of
        tachycardia >120/min                 Irregular heart beat




  YES                           NO
                                             Ectopic beats
  SVT                   Sinus tachycardia         AF
   VT                   High stroke volume
Physical examination
Key features of physical examination
  that will help confirm the presence of
  arrhythmia as a cause for the
  palpitations include
 Measurement of vital signs
 Assessment of the jugular venous
  pressure and pulse
 Auscultation of the chest and
  precordium
INVESTIGATIONS
 A resting ECG
 If exertion is known to induce arrhythmia
  and accompanying palpitations ,
  exercise ECG is useful
 2D-ECHO


When patients complaining of palpitations
 undergo 24-hour, ambulatory ECG
 monitoring, 39 to 85 percent manifest a
 rhythm disturbance (most being benign
 and clinically insignificant).
Premature ventricular contraction-
Bigeminy
If arrhythmia is sufficiently infrequent , other
   methods must be used like

       Continuous ECG (Holter) monitoring ,
       Telephonic monitoring ,
       Loop recordings (external or implantable)
    &
       Mobile cardiac outpatient telemetry.
       Event recorder
Holter monitor
Implantable loop recorders
Mobile cardiac outpatient telemetry
   Recent data suggests holter
    monitoring is of limited clinical utility
    while implantable loop recorder and
    mobile cardiac outpatient telemetry
    are safe and more cost effective in
    assessment of patients with recurrent ,
    unexplained palpitations
MANAGEMENT

   Occasional benign atrial or ventricular
    premature contractions can often be
    managed with beta blocker therapy if
    sufficiently troubling to the patient
   Palpitations incited by alcohol ,
    tobacco , illicit drugs need to be
    managed by abstention , while those
    caused by pharmacological agents
    should be managed by considering
    alternate therapies when possible
   Psychiatric causes of palpitations may
    benefit from cognitive or
    pharmacotherapies

   Once serious causes for the symptom
    have been excluded , the patient
    should be reassured that palpitations
    will not adversely affect prognosis
Management in a Nutshell

1.     Re-assurance
2.     Lifestyle modification
3.     Correction of co-morbid diseases
4.    Anxiolytics and Beta-blockers
5.    Anti-arrhythmic drugs / electrical
      conversion

    Recurrent life-threatening ventricular
     arrhythmias are currently being treated
     with Implantable Cardioverter-defibrillitor
     devices
Thank You

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Understanding Palpitations: Causes, Evaluation and Management

  • 1. PALPITATIONS Dr POLAMURI TABITHA PG FIRST YR
  • 2. DEFINITION  Uncomfortable awareness of heart beat or undue awareness of heart action.  Defined as thumping , pounding or fluttering sensation in the chest.  This sensation can be either intermittent or sustained and either regular or irregular
  • 3. Most patients interpret palpitations as unusual awareness of the heart beat and become concerned when they sense that they had skipped or missing heartbeats.  They are often noted when the patient is quietly resting , during which time other stimuli are minimal.
  • 4. PHYSIOLOGY Palpitation is due to  Alteration in heart rate Eg: sinus tachycardia & bradycardia  Alteration in heart rhythm Eg: Atrial fibrillation  Augmentation of myocardial contraction Eg: anxiety states & drugs
  • 5. NATURE OF PALPITATIONS FEATURE SUGGESTS HEART MISSES AND THUMPS ECTOPIC BEATS WORSE AT REST ECTOPIC BEATS VERY FAST REGULAR SVT / VT SUDDEN ONSET SVT / VT OFFSET WITH VAGAL MANOEUVRES SVT FAST AND IRREGULAR AF and ATRIAL FLUTTER with varying block FORCEFUL AND REGULAR – NOT FAST AWARENESS OF SINUS RHYTHM (ANXIETY) SEVERE DIZZINESS OR SYNCOPE VT or BRADYARRHYTHMIAS PRE-EXISTING HEART FAILURE VT
  • 6. CAUSES OF PALPITATIONS CARDIAC PSYCHIATRI C 43% 31% MISCELLANEOU UNKNOWN S 10% 16%
  • 7. Cardiovascular Causes Arrhythmias  Premature atrial and ventricular contractions  Supraventicular and ventricular arrhythmias  WPW syndrome  Atrial fibrillation  Atrial flutter with varying block  Brady-arrhythmias : complete heart block  Sick-sinus syndrome
  • 8. Non-arrhythmic cardiac causes  Mitral valve prolapse (with or without associated arrhythmias)  Aortic insufficiency  Atrial myxoma  Pulmonary embolism  Congenital heart ds  Systemic hypertension  Pericarditis  Pacemaker induced tachycardia
  • 9. Psychiatric Causes  Panic attacks  Anxiety states  Somatization Patients with psychiatric causes for palpitations more commonly report a longer duration of sensation >15min & multiplicity of symptoms than do patients with other causes
  • 10. The physician must remember that panic disorder and significant arrhythmias are not mutually exclusive, and that cardiac evaluation still may be necessary in patients with suspected panic disorder.  Arrhythmic causes must be ruled out before the diagnosis of anxiety or panic disorder can be accepted as the cause of the palpitations.
  • 11. Miscellaneous Causes  Hyperkinetic circulatory states : Anaemia , Fever , Thyrotoxicosis , Hypoglycemia , Phaechromocytoma  Drugs : Aminophylline , Atropine , Thyroxine , Tricyclic antidepressants , Vasodilators , Digitalis  Others : Caffeine , Cocaine , Amphetamines , Tobacco , Ethanol
  • 12.  Spontaneous skeletal muscle contractions of the chest wall  Systemic mastocytosis  Physiological : exertion , excitement , pregnancy  Neurocirculatory asthenia or Da costa’s syndrome or Effort syndrome or Soldier’s heart  Vaso-vagal attack
  • 13. APPROACH TO THE PATIENT WITH PALPITATIONS “Principal goal in assessing patients with palpitations is to determine if the symptom is caused by a life threatening arrhythmia”
  • 14. History “Patients with coronary artery disease or risk factors for CAD are at greater risk for ventricular arrhythmias as a cause for palpitations” In addition , the association of palpitations with other symptoms suggesting haemodynamic compromise including syncope or lightheadedness supports this diagnosis
  • 15. Remember “All palpitations are not arrhythmias and many arrhythmias do not palpitate”
  • 16. HOW TO EVALUATE PALPITATION STEP 1  Is palpitation continuous or intermittent ? Intermittent P. are commonly caused by premature atrial or ventricular contractions : the post extrasystolic beat is sensed by the patient owing to the increase in ventricular end-diastolic dimension following the pause in the cardiac cycle and the increased strength of contraction (post-extrasystolic potentiation)
  • 17. STEP 2 Is heart beat regular or irregular ?  Regular , sustained palpitations can be caused by SVT and VT  Irregular , sustained palpitations can be caused by Atrial fibrillation
  • 18. STEP 3 : What is the ~ heart rate ?  STEP 4 : Does palpitations occur in discrete attacks ? Is onset abrupt? How do attacks terminate? -Ventricular arrhythmias are of sudden onset -Holding breath or vagal manoeuvres decrease palpitations in SVT
  • 19. STEP 5 Are there any associated symptoms ?  Chest pain : Arrhythmogenic MI  Dyspnoea : Heart failure due to arrhythmias  Syncope : low cardiac output during arrhythmias , hypoglycemia , phaechromocytoma  Polyuria : SVT  Sweating : Anxiety ,hypoglycemia  Diarrhoea : Thyrotoxicosis
  • 20. STEP 6 :  Are there any precipitating factors ? exercise , stress (hyperdynamic cardiovascular states caused by catecholaminergic stimulation) alcohol intake , drugs STEP 7 :  Is there a history of structural heart disease ? coronary heart ds , valvular heart ds
  • 21. “It is often useful either to ask the patient to tap out the rhythm of the palpitations or to take his / her pulse while experiencing palpitations”
  • 22. Palpitations that are positional  generally reflect a structural process within heart Eg : Atrial myxoma  or adjacent to the heart Eg : Mediastinal mass
  • 23. SIMPLE APPROACH TO DIAGNOSIS OF PALPITATION Is heart beat regular ? YES NO Are there any discrete attacks of tachycardia >120/min Irregular heart beat YES NO Ectopic beats SVT Sinus tachycardia AF VT High stroke volume
  • 24. Physical examination Key features of physical examination that will help confirm the presence of arrhythmia as a cause for the palpitations include  Measurement of vital signs  Assessment of the jugular venous pressure and pulse  Auscultation of the chest and precordium
  • 25. INVESTIGATIONS  A resting ECG  If exertion is known to induce arrhythmia and accompanying palpitations , exercise ECG is useful  2D-ECHO When patients complaining of palpitations undergo 24-hour, ambulatory ECG monitoring, 39 to 85 percent manifest a rhythm disturbance (most being benign and clinically insignificant).
  • 27. If arrhythmia is sufficiently infrequent , other methods must be used like  Continuous ECG (Holter) monitoring ,  Telephonic monitoring ,  Loop recordings (external or implantable) &  Mobile cardiac outpatient telemetry.  Event recorder
  • 31. Recent data suggests holter monitoring is of limited clinical utility while implantable loop recorder and mobile cardiac outpatient telemetry are safe and more cost effective in assessment of patients with recurrent , unexplained palpitations
  • 32. MANAGEMENT  Occasional benign atrial or ventricular premature contractions can often be managed with beta blocker therapy if sufficiently troubling to the patient
  • 33. Palpitations incited by alcohol , tobacco , illicit drugs need to be managed by abstention , while those caused by pharmacological agents should be managed by considering alternate therapies when possible
  • 34. Psychiatric causes of palpitations may benefit from cognitive or pharmacotherapies  Once serious causes for the symptom have been excluded , the patient should be reassured that palpitations will not adversely affect prognosis
  • 35. Management in a Nutshell 1. Re-assurance 2. Lifestyle modification 3. Correction of co-morbid diseases 4. Anxiolytics and Beta-blockers 5. Anti-arrhythmic drugs / electrical conversion  Recurrent life-threatening ventricular arrhythmias are currently being treated with Implantable Cardioverter-defibrillitor devices
  • 36.