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Physiological response to high
barometric pressure
Hyperbarism:
• When human beings descend beneath the sea, the
pressure around them increases tremendously and
exposes the blood in the lungs to extremely high alveolar
gas pressure.
Relationship of pressure to sea depth
Boyle’s law:
Volume 1/Îą Pressure
Effect of High Partial Pressures of Individual
Gases on the Body
• Nitrogen Narcosis
• Oxygen Toxicity
Nitrogen Narcosis
• At 120 feet feels joviality & careless
• At 150 to 200 feet, the diver becomes drowsy.
• At 200 to 250 feet, loss of strength.
• Beyond 250 feet, becomes unconsciousness
Nitrogen narcosis similar like alcohol intoxication
Nitrogen reacts with fatty acids in cell memb of neurons and
impairs the conduction like gas anesthetics
Oxygen Toxicity
Acute oxygen poisoning:
•Nausea
•muscle twitchings
•dizziness
•disturbances of vision
•Irritability
•Disorientation
•seizures followed by coma
Generation of oxygen free radicals swamp the
enzyme system to remove it
Reacts with polyunsaturated fattyacids of cell
memb causes brain dysfunction
Chronic Oxygen Poisoning: Causes Pulmonary edema
Decompression of the diver after excess
exposure to high pressure
Decompression Sickness (Synonyms: Bends, Compressed Air
Sickness, Caisson Disease, Diver’s Paralysis, Dysbarism)
Symptoms:
• Pain in the joints
• Pain in the muscles of arms & neck
• Nervous system symptoms: dizziness, paralysis &
unconsciousness
• Shortness of breathing (chokes)
• Death
Physiological principles of prevention and
management of decompression sickness
Decompression table:
60 minutes at a depth of 190 feet
• 10 minutes at 50 feet depth
• 17 minutes at 40 feet depth
• 19 minutes at 30 feet depth
• 50 minutes at 20 feet depth
• 84 minutes at 10 feet depth
Decompression chamber
Scuba (Self-Contained Underwater Breathing Apparatus)
Diving
Contains oxygen & helium
Helium
• Has only about one fifth the narcotic effect of nitrogen
• Only about one half as much volume of helium dissolves
in the body tissues as nitrogen
• Low density of helium (one seventh the density of
nitrogen) keeps the airway resistance for breathing at a
minimum work of breathing
The deepest SCUBA dive record-Ahmed garb,
1090 ft in Red sea
Thank you

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Physiological response to high barometric pressure

  • 1. Physiological response to high barometric pressure
  • 2. Hyperbarism: • When human beings descend beneath the sea, the pressure around them increases tremendously and exposes the blood in the lungs to extremely high alveolar gas pressure.
  • 3. Relationship of pressure to sea depth Boyle’s law: Volume 1/Îą Pressure
  • 4. Effect of High Partial Pressures of Individual Gases on the Body • Nitrogen Narcosis • Oxygen Toxicity
  • 5. Nitrogen Narcosis • At 120 feet feels joviality & careless • At 150 to 200 feet, the diver becomes drowsy. • At 200 to 250 feet, loss of strength. • Beyond 250 feet, becomes unconsciousness Nitrogen narcosis similar like alcohol intoxication Nitrogen reacts with fatty acids in cell memb of neurons and impairs the conduction like gas anesthetics
  • 6. Oxygen Toxicity Acute oxygen poisoning: •Nausea •muscle twitchings •dizziness •disturbances of vision •Irritability •Disorientation •seizures followed by coma Generation of oxygen free radicals swamp the enzyme system to remove it Reacts with polyunsaturated fattyacids of cell memb causes brain dysfunction Chronic Oxygen Poisoning: Causes Pulmonary edema
  • 7. Decompression of the diver after excess exposure to high pressure
  • 8. Decompression Sickness (Synonyms: Bends, Compressed Air Sickness, Caisson Disease, Diver’s Paralysis, Dysbarism) Symptoms: • Pain in the joints • Pain in the muscles of arms & neck • Nervous system symptoms: dizziness, paralysis & unconsciousness • Shortness of breathing (chokes) • Death
  • 9. Physiological principles of prevention and management of decompression sickness Decompression table: 60 minutes at a depth of 190 feet • 10 minutes at 50 feet depth • 17 minutes at 40 feet depth • 19 minutes at 30 feet depth • 50 minutes at 20 feet depth • 84 minutes at 10 feet depth Decompression chamber
  • 10. Scuba (Self-Contained Underwater Breathing Apparatus) Diving Contains oxygen & helium
  • 11. Helium • Has only about one fifth the narcotic effect of nitrogen • Only about one half as much volume of helium dissolves in the body tissues as nitrogen • Low density of helium (one seventh the density of nitrogen) keeps the airway resistance for breathing at a minimum work of breathing
  • 12. The deepest SCUBA dive record-Ahmed garb, 1090 ft in Red sea