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Self-renewal vs. Differentiation of Mouse Embryonic Stem Cells  TVGH Journal Club, introduced by Dr.  張宏吉 , May 6, 2008. K. Sue O'Shea  2004 Biology of Reproduction Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan
ABSTRACT  ,[object Object]
Copyright ©2004 Society for the Study of Reproduction O'Shea, K. S. Biol Reprod 2004;71:1755-1765 Biology of Reproduction FIG. 1. Development of the early mouse embryo from the E2.5 morula to the E6.5 gastrula... Primitive endoderm Epiblast
STEM CELL CHARACTERISTICS  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Oct-4  ,[object Object],[object Object],[object Object]
NANOG  ,[object Object],[object Object],[object Object],[object Object],[object Object]
Foxd 3 & Sox2  ,[object Object],[object Object]
Copyright ©2004 Society for the Study of Reproduction O'Shea, K. S. Biol Reprod 2004;71:1755-1765 Biology of Reproduction FIG. 2. Neuronal differentiation of Tau-EGFP ES cells...
LESSONS FOR THE EMBRYO: NEW GENES, NEW FUNCTIONS  ,[object Object],[object Object],[object Object],[object Object]
CONCLUSIONS  ,[object Object],[object Object],[object Object]
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors Kazutoshi Takahashi1 and Shinya Yamanaka (Kyoto University), 2006 Cell ,[object Object],[object Object]
Reprogramming of human somatic cells to pluripotency with defined factors In-Hyun Park(Harvard University), 2007 Nature ,[object Object]

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education_11-24

  • 1. Self-renewal vs. Differentiation of Mouse Embryonic Stem Cells TVGH Journal Club, introduced by Dr. 張宏吉 , May 6, 2008. K. Sue O'Shea 2004 Biology of Reproduction Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan
  • 2.
  • 3. Copyright ©2004 Society for the Study of Reproduction O'Shea, K. S. Biol Reprod 2004;71:1755-1765 Biology of Reproduction FIG. 1. Development of the early mouse embryo from the E2.5 morula to the E6.5 gastrula... Primitive endoderm Epiblast
  • 4.
  • 5.
  • 6.
  • 7.
  • 8. Copyright ©2004 Society for the Study of Reproduction O'Shea, K. S. Biol Reprod 2004;71:1755-1765 Biology of Reproduction FIG. 2. Neuronal differentiation of Tau-EGFP ES cells...
  • 9.
  • 10.
  • 11.
  • 12.