proton pump inhibitors PPT

SEMINAR ON PROTON PUMP INHIBITORS. SUBMITTED BY AVS.PRAVEEN KUMAR 07P25R0005. UNDER THEGUIDENCE OF Mr. K.SURENDRA Assistant professor,M.Pharm, RAO’S COLLEGE OF PHARMACY

PEPTIC ULCER . ,[object Object],[object Object],[object Object]

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ANTI ULCER DRUGS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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PROTON PUMP INHIBITORS DRUG OF CHOICE ,[object Object],[object Object],[object Object],[object Object],[object Object]

Omeprazole. The proton pump inhibitor OMEPRAZOLE

OMEPRAZOLE . Systematic ( IUPAC ) name 6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl) methylsulfinyl)-1 H -benzo[ d ]imidazole Chemical data Formula C 17 H 19 N 3 O 3 S Mol. mass 345.4 g/mol Pharmacokinetic data Bioavailability 35–60% Metabolism Hepatic ( CYP2C19 , CYP3A4 ) Half life 1 - 1.2 hours Excretion 80% Renal 20% Faecal Therapeutic considerations Routes Oral, IV

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METABOLISM ,[object Object],[object Object]

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MECHANISM OF ACTION OF OMEPRAZOLE ,[object Object],[object Object],[object Object],[object Object],[object Object]

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Omeprazole 20 mg, Capsules Omeprazole 10 mg, Capsules OMEZ :10, 20, 40,mg capsules. PROTOLOC :20, 40,mg capsules. ,[object Object]

OTHER DRUGS ,[object Object],[object Object],[object Object],[object Object]

REFFERENCE Essentials of medical pharmacology, by KD. Thripathi. Pharmacology & pharmaco therapeutics, by R.S. satoshkar. Text book of medical pharmacology, by Padmaja uday kumar. Pharmacology & clinical pharmaco kinetics, by G. Kutzung. Www. Proton pump inhibitor wikipedia, the free encyclopedia.

proton pump inhibitors PPT

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proton pump inhibitors PPT