2. Background
• Peri-implant disease : An inflammatory reaction around the tissue
surrounding an implant consist of two forms
• Peri-implant mucositis
• Peri-implantitis
Mombelli A. et al. Periodontol 2000 1998;17:63-76.
The Sixth European Workshop on Periodontoloy 2008
3. Peri-implant mucositis
• The presence of inflammation
• Confine to the soft tissue
• No signs of loss of supporting bone following initial bone remodeling
• Reversible condition : early intervention and remove etiology
San M. et al. J Clin Periodontol 2012;39(Suppl.12):202-206.
4. Peri-implant mucositis
• Clinical findings
• Bleeding on probing / gingival redness
• Probing depth ≥ 4 mm
• No radiographic bone loss
• Prevalence : 48% of implants
San M. et al. J Clin Periodontol 2012;39(Suppl.12):202-206.
Roos-Jansaker AM. J Clin Periodontol 2006;33:290-295.
7. • Progressive loss of supporting bone beyond biological bone remodeling
• Mean crestal bone loss of 0.9-1.6 mm in first post-surgical year
• Then annual bone loss of 0.02-0.15 mm
• In case of no baseline radiograph, 2 mm vertical distance from expected marginal bone level
• Prevalence : varied from 11%-47% depending on the threshold used
Peri-implantitis
Koldlands OC. et al. J Periodontol 2010;81:231-238.
San M. et al. J Clin Periodontol 2012;39(Suppl.12):202-206.
9. Etiologies
• Formation of biofilm
• Gram-negative anaerobic bacteria : similar to natural teeth in periodontal
disease
• Peri-implant mucositis – Gingivitis
• Peri-implantitis – Periodontitis : S.aureus could be found as the initiation of peri-
implantitis
Heit-Mayfield LJ. et al. Periodontol 2000 2010;53:167-181.
Leohardt A. et al. Clin Oral Implants Res 1999;10:399-345.
10. Factors associated Peri-implantitis
• History of periodontitis : two times
• Smoking : 3-4 times increased risk for peri-implantitis
• Residual cement : Rough area beneath gingival margin Bacterial
attachment
• Implant position and design : inability to clean
Mombelli A. et al. Clin Oral Implants Res 2012;23(Suppl.6):67-76.
Linkevicius T. et al. Clin Oral Implants Res 2012 published online
14. Non-Surgical treatment
• Mechanical debridement
• Ultrasonic scaler
• Hand instruments : Plastic curette
• Rubber cup & pumice
• Plaque control
15.
16. • Effective in Peri-implant mucositis
• carbon fibers curette, rubber cup, pumice
• In peri-implantitis, mechanical debridement alone was found not to be
effective
Non-Surgical treatment
17. • Use in conjunction with mechanical debridement and chemical disinfection
• Local : high concentration, reduce side & adverse effect
• Tetracyclin HCL (Actisite® )
• Minocyclin
• Systemic : ornidazole 1000 mg daily, metronidazole, amoxicillin
Antibiotic
28. Conclusions
• Non-surgical treatment alone was found to be effective in peri-implant
mucositis : carbon fibers curette, rubber cup, pumice
• Peri-implantitis with mild bone loss : Mechanical debridement,
Antiseptic(CHX mouthwash), Systemic/Local Antibiotic, Resective surgery
• Peri-implantitis with moderate bone loss : Mechanical debridement,
Antiseptic(CHX mouthwash), Systemic/Local Antibiotic, Open flap
debridement, Surface decontamination, Regenerative surgery
30. Conclusions
• Bone fill & Re-osseointegraion
• Regenerative procedure > Open flap debridement
• Membrane did not improve treatment outcome in comparison to the use of
autogenous bone alone
• Systemic antibiotic (Amoxicilin plus metronidazole) and antiseptic mouthrinse(CHX) :
improved clinical outcomes
31. Conclusions
• No single method of surface decontamination(Chemical agents, air abrasive,
lasers) was found to be superior
• Citric acid(40%,30-60 sec) has proved to be most effective agent for bacterial
growth reduction on HA surfaces
• The simplest method of surface decontamination; gauze soaked alternately
in CHX and saline, should be preferred when combined with membrane-
covered autogenous bone graft