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Observation Medicine and
Clinical Decision Units

Paleerat Jariyakanjana, MD
Faculty of Medicine, Naresuan University
14 Nov 2013
Principles of observation medicine
• extension of ED services
• improve patient care by continuing the
evaluation and management of selected ED
patients who would otherwise require admission
• short-term services for up to 24 hours
• Names given to observation units
– chest pain unit, clinical decision unit, and rapid
diagnostic treatment unit
Principles of observation medicine
• not a holding unit
• holding unit
– stems from hospital overcrowding
– area where patients admitted to the hospital are held
passively until they can be transferred to an inpatient
hospital bed
Principles of observation medicine
The observation approach
traditional ED
• lasts 2-3 hours
• performs a history and physical examination and
orders laboratory and radiologic tests
• When the test results return, the physician either
admits the patient to the hospital or discharges
the patient home.
The observation approach
• The observation approach adds a third option at
the completion of the ED evaluation.
• The patient is treated and further tested for up to
24 hours.
• After the observation period, patients are then
admitted to the hospital or discharged home.
The observation approach
• observation orders
–
–
–
–
–
–

clinical impression
reason for observation
therapeutic evaluation plan
expected outcome
criteria and time frame for disposition
physician responsible for the patient’s care and
disposition
The observation approach
Nursing staff
• average staff
– monitored beds: 1:4-6
– nonmonitored beds: 1:6-9
The observation approach
Nursing staff
• broad based skills
• all skills present in emergency nurses
• When nonemergency nurses are recruited for
the observation unit, they should be crosstrained, serving some shifts each month in the
ED.
The observation approach
Physician staffing
• Additional physician staffing is also required for
the observation unit.
• full-time equivalent: 1:2000 patients observed
per year
CLINICAL CONDITIONS
Abdominal Pain
Abdominal Pain
• NPO & IVF
• Serial abdominal examinations are repeated at
4-hour intervals and laboratory tests repeated
• Imaging and consultations
• hospitalized
– have no improvement
– have clinical deterioration
– have surgical pathology diagnosed by testing
Chest Pain
Chest Pain
• Low-intermediate risk of AMI
• serially tested with cardiac markers and ECGs
• CK-MB estimation at 0, 3, 6, and 9 hours after
presentation has 100% sensitivity, 98%
specificity, and 100% negative predictive value
in the detection of AMI.
• monitored with continuous ECG monitors
Chest Pain
• After evaluation to exclude AMI, the patient is
evaluated for possible acute coronary ischemia.
• performed before release of the patient from the
observation unit or at follow-up evaluation within
72 hours of discharge
• most common testing modality used: exercise
stress testing.
• Patients who obtain their target heart rate
without ECG evidence of ischemia can be
released home.
Deep Vein Thrombosis
• role
– diagnostic testing
– initiation of therapy using LMWH
– patient education

• present when definitive tests for DVT are not
available
• short term with 1 dose of LMWH until the
diagnosis can be clarified
• If the diagnosis is confirmed, the patient can be
admitted or treated as an outpatient based on
hospital protocol.
Upper Gastrointestinal Bleeding
• outpatient management is possible if patients at
high risk for further bleeding can be identified
• In an attempt to refine diagnostic accuracy, risk
assessment, and disposition, several scoring
systems have been developed.
• Some use a period of observation with early
endoscopy to identify the patient who can be
discharged early.
Syncope
Syncope
• 1-year risk of dysrhythmia or death
– abnormal ECG, history of ventricular
dysrhythmia, history of heart failure, and age >45
years

• none of these risk factors
– 4.4% rate of adverse events at 1 year
– outpatient evaluation

• 3-4 risk factors
– 58% adverse outcome rate
– admitted to the hospital

• 1-2 risk factors
– intermediate risk
– outpatient evaluation with observation
Syncope
•
•
•
•
•
•

Continuous ECG monitoring
consultation
serial cardiac enzymes
further tests: echography
psychiatric assessment (25%)
tilt table testing
Transient Ischemic Attack
• Traditionally: hospitalized
–
–
–
–
–

serial clinical evaluations
neurology consultation
carotid Doppler testing
Echocardiography
cardiac monitoring
Transient Ischemic Attack
• Recommendations regarding the disposition of
ED patients with transient ischemic attack
remain vague.
• Treatment of transient ischemic attack patients
in an EDOU has been suggested as an
alternative.

State of the Art: Observation Units in the Emergency Department, ACEP 2011
Blunt Abdominal Injury
• no clear evidence of serious injury on physical
examination but remain at risk
• Evaluations during observation for up to 23
hours
– repeat physical examinations, laboratory
testing, imaging, and specialty consultations
Penetrating Abdominal Injury
• A period of observation can identify those
patients who do not require surgical intervention.
• serial examinations by the physician, further
diagnostic testing, and specialty consultation
• stab wounds to the abdomen with peritoneal
breach but a negative finding on diagnostic
laparoscopy or imaging with CT scan or
ultrasonography
• tangential gunshot wounds can avoid surgery
with observation if they are hemodynamically
stable and have initial negative test findings
Blunt Chest Trauma
• isolated BCT who are otherwise stable with
normal ECG are suitable for a period of
observation to exclude myocardial injury
• monitored with continuous ECG, specifically
assessing for dysrhythmias
• Serial enzyme determinations
• sternal fractures or other evidence of higher risk
of intrathoracic injury  transesophageal
echocardiogram
Blunt Chest Trauma
• negative evaluations during the period of
observation  released home for outpatient
follow-up
• Patients who have isolated chest wall contusions
and no abnormality of serial CK-MB, troponin, or
ECG abnormalities or dysrhythmia during 6 to 12
hours of ECG monitoring are unlikely to have
complications.
Penetrating Chest Injury
• Patients with evidence of a small pneumothorax
or hemothorax can be monitored for
deterioration.
• monitored for respiratory or hemodynamic
compromise
• Repeat chest radiographs can detect the
development of hemothorax or pneumothorax.
Penetrating Chest Injury
• managing asymptomatic stab wound victims in
the short-term observation unit
• penetrating wounds to the cardiac area of the
chest (between the nipples), the region of the
great vessels, or the thoracoabdominal area
– Echocardiography

• Patients with a negative echocardiography can
be observed in the observation unit.
Asthma
• extended, shortterm intensive protocol for 8-12
hours in an observation unit
Asthma
• Exclusion criteria
– unstable vital signs
– evidence of impending respiratory failure (Paco2 > 45
mm Hg, Pao2 < 55 mm Hg)
– severe airway restriction (PEFR < 80 L/min after first
inhaled beta-agonist treatment)
Asthma
• continuation of ED treatment with handheld
nebulized beta-agonists every 2-4 hours and
repeated steroids at 6 hours after initial therapy
• Patients are managed up to 23 hours but
generally are admitted to the hospital if they do
not respond within 12 hours.
• D/C
– not in respiratory distress, have minimal residual
symptoms, and have a PEFR of ≥70% of predicted or
personal best
Atrial Fibrillation
• new and acute atrial fibrillation
• period of observation: 8-12 hours
• treated to rectify their dysrhythmia and evaluated
for serious precipitants of their condition
• used to detect structural heart disease with the
use of echocardiography
Atrial Fibrillation
Atrial Fibrillation
• spontaneous conversion rate
– 50-70% within the first 24 hours
– low rate of structural heart disease

• Those who do not spontaneously convert in the
first 8 hours can be converted chemically or
electrically.
• After cardioversion, the patient needs to be
observed.
Congestive Heart Failure
Congestive Heart Failure
• Patients with BNP levels between 100 and 500
pg/mL are suitable candidates for observation
unit care
• Therapy and evaluation are a continuation of the
initial 2- or 3-hour ED visit for up to 23 hours.
• Continuous ECG monitoring for dysrhythmias
• continuous infusion of loop diuretic (0.05–0.1
mg/kg/hr) titrated hourly to a net fluid balance of
-1 mL/kg/hr
Dehydration
Dehydration
• Exclusion criteria
– high risk patients: renal failure, congestive heart
failure, liver failure
– hemodynamic instability
State of the Art: Observation Units in the Emergency Department, ACEP 2011

• intravenous rehydration, serial examination and
vital signs, and antiemetics
Pneumonia
Pneumonia
• antibiotics, oxygen therapy, and pulse oximetry
monitoring
• After 10-12 hours of treatment in the observation
unit, the patient is reevaluated and a decision
about disposition is made.
Cellulitis
• Exclusion criteria
– severe pain (possible deep infection), tissue
necrosis, neck abscess, peripheral vascular
disease, foreign bodies, bite wounds, and specific
locations (hand, orbit, joints, scrotum, neck)
– Immunocompromised: diabetics, cancer
patients, patients on immunosuppressants, and
patients with HIV
– intravenous drug use, gender, a positive communityacquired MRSA culture, age, presence of medical
insurance, drainage of an abscess in the
ED, diabetes and WBC >15,000

State of the Art: Observation Units in the Emergency Department, ACEP 2011
Cellulitis
• monitor for rapidly progressing cellulitis or
necrotizing fasciitis

State of the Art: Observation Units in the Emergency Department, ACEP 2011
Pyelonephritis
• appropriate for adult, nonpregnant women who
appear to have uncomplicated pyelonephritis
• initial dose of intravenous antibiotic, intravenous
fluids, antiemetic, and antipyretic
• D/C
– clinically stable and able to tolerate oral fluids after 12
hours of treatment
Pyelonephritis
• I/C
– severe pain, vomiting and high fevers

State of the Art: Observation Units in the Emergency Department, ACEP 2011
Treatment of painful conditions
• sickle cell disease, severe back
pain, headache, urolithiasis, and orthopedic pain
• pain management plan, perform patient
controlled analgesia, and obtain consultation
from specialists

State of the Art: Observation Units in the Emergency Department, ACEP 2011
Patients at risk for self harm
• Antidote administration, monitoring of serum
drug levels and social and psychiatric
management
• Inclusion criteria
– asymptomatic adult patients (age ≥15 years) who
presented after known or suspected potentially toxic
deliberate ingestion

State of the Art: Observation Units in the Emergency Department, ACEP 2011
Patients at risk for self harm
• exclusion criteria
– patients with isolated alcohol intoxication, ingestion of
sustained release preparation, chronic drug
intoxication, elevated drug levels requiring prolonged
medical therapy, end organ toxicity upon
arrival, persistent self injurious or violent behavior
possessing a serious threat to safety of
patient, nursing and ancillary staff
– patients that exhibited high risk criteria for
deterioration after ingestion of an antidepressant

State of the Art: Observation Units in the Emergency Department, ACEP 2011
NUH EDOU
 Chest Pain
 CHF
 Dehydration
 Treatment of painful
conditions















Abdominal Pain
DVT
UGIB
Syncope
TIA
Blunt/Penetrating Abdominal
Injury
Blunt/Penetrating Chest
Trauma
Asthma
Atrial Fibrillation
Pneumonia
Cellulitis
Pyelonephritis
Patients at risk for self harm
Reference
• Rosen’s emergency medicine—7th ed.
• State of the Art: Observation Units in the
Emergency Department, ACEP 2011
ANY QUESTIONS?

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Observation medicine and clinical decision units

  • 1. Observation Medicine and Clinical Decision Units Paleerat Jariyakanjana, MD Faculty of Medicine, Naresuan University 14 Nov 2013
  • 2. Principles of observation medicine • extension of ED services • improve patient care by continuing the evaluation and management of selected ED patients who would otherwise require admission • short-term services for up to 24 hours • Names given to observation units – chest pain unit, clinical decision unit, and rapid diagnostic treatment unit
  • 3. Principles of observation medicine • not a holding unit • holding unit – stems from hospital overcrowding – area where patients admitted to the hospital are held passively until they can be transferred to an inpatient hospital bed
  • 5. The observation approach traditional ED • lasts 2-3 hours • performs a history and physical examination and orders laboratory and radiologic tests • When the test results return, the physician either admits the patient to the hospital or discharges the patient home.
  • 6. The observation approach • The observation approach adds a third option at the completion of the ED evaluation. • The patient is treated and further tested for up to 24 hours. • After the observation period, patients are then admitted to the hospital or discharged home.
  • 7. The observation approach • observation orders – – – – – – clinical impression reason for observation therapeutic evaluation plan expected outcome criteria and time frame for disposition physician responsible for the patient’s care and disposition
  • 8. The observation approach Nursing staff • average staff – monitored beds: 1:4-6 – nonmonitored beds: 1:6-9
  • 9. The observation approach Nursing staff • broad based skills • all skills present in emergency nurses • When nonemergency nurses are recruited for the observation unit, they should be crosstrained, serving some shifts each month in the ED.
  • 10. The observation approach Physician staffing • Additional physician staffing is also required for the observation unit. • full-time equivalent: 1:2000 patients observed per year
  • 13. Abdominal Pain • NPO & IVF • Serial abdominal examinations are repeated at 4-hour intervals and laboratory tests repeated • Imaging and consultations • hospitalized – have no improvement – have clinical deterioration – have surgical pathology diagnosed by testing
  • 15. Chest Pain • Low-intermediate risk of AMI • serially tested with cardiac markers and ECGs • CK-MB estimation at 0, 3, 6, and 9 hours after presentation has 100% sensitivity, 98% specificity, and 100% negative predictive value in the detection of AMI. • monitored with continuous ECG monitors
  • 16. Chest Pain • After evaluation to exclude AMI, the patient is evaluated for possible acute coronary ischemia. • performed before release of the patient from the observation unit or at follow-up evaluation within 72 hours of discharge • most common testing modality used: exercise stress testing. • Patients who obtain their target heart rate without ECG evidence of ischemia can be released home.
  • 17. Deep Vein Thrombosis • role – diagnostic testing – initiation of therapy using LMWH – patient education • present when definitive tests for DVT are not available • short term with 1 dose of LMWH until the diagnosis can be clarified • If the diagnosis is confirmed, the patient can be admitted or treated as an outpatient based on hospital protocol.
  • 18. Upper Gastrointestinal Bleeding • outpatient management is possible if patients at high risk for further bleeding can be identified • In an attempt to refine diagnostic accuracy, risk assessment, and disposition, several scoring systems have been developed. • Some use a period of observation with early endoscopy to identify the patient who can be discharged early.
  • 20. Syncope • 1-year risk of dysrhythmia or death – abnormal ECG, history of ventricular dysrhythmia, history of heart failure, and age >45 years • none of these risk factors – 4.4% rate of adverse events at 1 year – outpatient evaluation • 3-4 risk factors – 58% adverse outcome rate – admitted to the hospital • 1-2 risk factors – intermediate risk – outpatient evaluation with observation
  • 21. Syncope • • • • • • Continuous ECG monitoring consultation serial cardiac enzymes further tests: echography psychiatric assessment (25%) tilt table testing
  • 22. Transient Ischemic Attack • Traditionally: hospitalized – – – – – serial clinical evaluations neurology consultation carotid Doppler testing Echocardiography cardiac monitoring
  • 23. Transient Ischemic Attack • Recommendations regarding the disposition of ED patients with transient ischemic attack remain vague. • Treatment of transient ischemic attack patients in an EDOU has been suggested as an alternative. State of the Art: Observation Units in the Emergency Department, ACEP 2011
  • 24. Blunt Abdominal Injury • no clear evidence of serious injury on physical examination but remain at risk • Evaluations during observation for up to 23 hours – repeat physical examinations, laboratory testing, imaging, and specialty consultations
  • 25. Penetrating Abdominal Injury • A period of observation can identify those patients who do not require surgical intervention. • serial examinations by the physician, further diagnostic testing, and specialty consultation • stab wounds to the abdomen with peritoneal breach but a negative finding on diagnostic laparoscopy or imaging with CT scan or ultrasonography • tangential gunshot wounds can avoid surgery with observation if they are hemodynamically stable and have initial negative test findings
  • 26. Blunt Chest Trauma • isolated BCT who are otherwise stable with normal ECG are suitable for a period of observation to exclude myocardial injury • monitored with continuous ECG, specifically assessing for dysrhythmias • Serial enzyme determinations • sternal fractures or other evidence of higher risk of intrathoracic injury  transesophageal echocardiogram
  • 27. Blunt Chest Trauma • negative evaluations during the period of observation  released home for outpatient follow-up • Patients who have isolated chest wall contusions and no abnormality of serial CK-MB, troponin, or ECG abnormalities or dysrhythmia during 6 to 12 hours of ECG monitoring are unlikely to have complications.
  • 28. Penetrating Chest Injury • Patients with evidence of a small pneumothorax or hemothorax can be monitored for deterioration. • monitored for respiratory or hemodynamic compromise • Repeat chest radiographs can detect the development of hemothorax or pneumothorax.
  • 29. Penetrating Chest Injury • managing asymptomatic stab wound victims in the short-term observation unit • penetrating wounds to the cardiac area of the chest (between the nipples), the region of the great vessels, or the thoracoabdominal area – Echocardiography • Patients with a negative echocardiography can be observed in the observation unit.
  • 30. Asthma • extended, shortterm intensive protocol for 8-12 hours in an observation unit
  • 31. Asthma • Exclusion criteria – unstable vital signs – evidence of impending respiratory failure (Paco2 > 45 mm Hg, Pao2 < 55 mm Hg) – severe airway restriction (PEFR < 80 L/min after first inhaled beta-agonist treatment)
  • 32. Asthma • continuation of ED treatment with handheld nebulized beta-agonists every 2-4 hours and repeated steroids at 6 hours after initial therapy • Patients are managed up to 23 hours but generally are admitted to the hospital if they do not respond within 12 hours. • D/C – not in respiratory distress, have minimal residual symptoms, and have a PEFR of ≥70% of predicted or personal best
  • 33. Atrial Fibrillation • new and acute atrial fibrillation • period of observation: 8-12 hours • treated to rectify their dysrhythmia and evaluated for serious precipitants of their condition • used to detect structural heart disease with the use of echocardiography
  • 35. Atrial Fibrillation • spontaneous conversion rate – 50-70% within the first 24 hours – low rate of structural heart disease • Those who do not spontaneously convert in the first 8 hours can be converted chemically or electrically. • After cardioversion, the patient needs to be observed.
  • 37. Congestive Heart Failure • Patients with BNP levels between 100 and 500 pg/mL are suitable candidates for observation unit care • Therapy and evaluation are a continuation of the initial 2- or 3-hour ED visit for up to 23 hours. • Continuous ECG monitoring for dysrhythmias • continuous infusion of loop diuretic (0.05–0.1 mg/kg/hr) titrated hourly to a net fluid balance of -1 mL/kg/hr
  • 39. Dehydration • Exclusion criteria – high risk patients: renal failure, congestive heart failure, liver failure – hemodynamic instability State of the Art: Observation Units in the Emergency Department, ACEP 2011 • intravenous rehydration, serial examination and vital signs, and antiemetics
  • 41.
  • 42. Pneumonia • antibiotics, oxygen therapy, and pulse oximetry monitoring • After 10-12 hours of treatment in the observation unit, the patient is reevaluated and a decision about disposition is made.
  • 43. Cellulitis • Exclusion criteria – severe pain (possible deep infection), tissue necrosis, neck abscess, peripheral vascular disease, foreign bodies, bite wounds, and specific locations (hand, orbit, joints, scrotum, neck) – Immunocompromised: diabetics, cancer patients, patients on immunosuppressants, and patients with HIV – intravenous drug use, gender, a positive communityacquired MRSA culture, age, presence of medical insurance, drainage of an abscess in the ED, diabetes and WBC >15,000 State of the Art: Observation Units in the Emergency Department, ACEP 2011
  • 44. Cellulitis • monitor for rapidly progressing cellulitis or necrotizing fasciitis State of the Art: Observation Units in the Emergency Department, ACEP 2011
  • 45. Pyelonephritis • appropriate for adult, nonpregnant women who appear to have uncomplicated pyelonephritis • initial dose of intravenous antibiotic, intravenous fluids, antiemetic, and antipyretic • D/C – clinically stable and able to tolerate oral fluids after 12 hours of treatment
  • 46. Pyelonephritis • I/C – severe pain, vomiting and high fevers State of the Art: Observation Units in the Emergency Department, ACEP 2011
  • 47. Treatment of painful conditions • sickle cell disease, severe back pain, headache, urolithiasis, and orthopedic pain • pain management plan, perform patient controlled analgesia, and obtain consultation from specialists State of the Art: Observation Units in the Emergency Department, ACEP 2011
  • 48. Patients at risk for self harm • Antidote administration, monitoring of serum drug levels and social and psychiatric management • Inclusion criteria – asymptomatic adult patients (age ≥15 years) who presented after known or suspected potentially toxic deliberate ingestion State of the Art: Observation Units in the Emergency Department, ACEP 2011
  • 49. Patients at risk for self harm • exclusion criteria – patients with isolated alcohol intoxication, ingestion of sustained release preparation, chronic drug intoxication, elevated drug levels requiring prolonged medical therapy, end organ toxicity upon arrival, persistent self injurious or violent behavior possessing a serious threat to safety of patient, nursing and ancillary staff – patients that exhibited high risk criteria for deterioration after ingestion of an antidepressant State of the Art: Observation Units in the Emergency Department, ACEP 2011
  • 50. NUH EDOU  Chest Pain  CHF  Dehydration  Treatment of painful conditions              Abdominal Pain DVT UGIB Syncope TIA Blunt/Penetrating Abdominal Injury Blunt/Penetrating Chest Trauma Asthma Atrial Fibrillation Pneumonia Cellulitis Pyelonephritis Patients at risk for self harm
  • 51. Reference • Rosen’s emergency medicine—7th ed. • State of the Art: Observation Units in the Emergency Department, ACEP 2011

Hinweis der Redaktion

  1. 1. These are patients whose diagnoses are unclear after the initial ED evaluation and who will benefit from further evaluation during observation.
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