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Burns



Anthony Holley
  Intensivist
    RBWH         Bedside Critical Care 2012
Acknowledgement

   Prof. Jeff Lipman




                   Bedside Critical Care 2012
Large tertiary ICU
  Only burns referral centre
  40 months
  n = 158



Bedside Critical Care 2012
Patient %
                                                  Bu




                                                                               10
                                                                                    15
                                                                                         20
                                                                                              25
                                                                                                       30
                                                                                                            35
                                                                                                                 40




                                                                       0
                                                                           5
                                                        rn
                                                          :0
                                                                -9
                                                Bu                %
                                                     rn
                                                       :1
                                                         0-
                                                              19
                                                                %
                                                  Bu
                                                        rn
                                                          :2
                                                            0-
                                                                 29
                                                  Bu
                                                        rn
                                                          :3
                                                            0-
                                                                 39
                                                  Bu
                                                        rn
                                                          :4
                                                            0-
                                                                 49
                                                  Bu
                                                        rn
                                                          :5




Bedside Critical Care 2012
                                                            0-
                                                                 59
                                                  Bu
                                                        rn

                             Burn %
                                                          :6
                                                            0-
                                                                                                   n =158




                                                                 69
                                                  Bu
                                                        rn
                                                          :7
                                                            0-
                                                                 79
                                                                                                                      Body Surface Area Burn Distribution




                                                  Bu
                                                        rn
                                                          :8
                                                            0-
                                                                 89
                                                 Bu
                                                       rn
                                                         :9
                                      Bu                   0-
                                           rn                  10
                                                of               0
                                                   o   ro
                                                         ph
                                                              ar
                                                                 ynx
Mortality

 8.22% mortality
 But …….0.68% in those with intention “to
  cure”




                              Bedside Critical Care 2012
Wallace’s Rule of Nine




                  Bedside Critical Care 2012
Classification




Bedside Critical Care 2012
First 24 HOURS


A    Airway assessment
B    Burn assessment
C    Circulation assessment




                     Bedside Critical Care 2012
AIRWAY




   60% of flame facial burns will
     have inhalational injury


              Bedside Critical Care 2012
Early Bronchoscopy




Nebulised heparin for inhalation injury
     and to ??prevent VAP

                                    Bedside Critical Care 2012
Alveolar Ridge/Maxillary Screws for ETT Fixation




                                 Bedside Critical Care 2012
•Resuscitation
•Assessment
•Heated rooms
•Theatre




                 Bedside Critical Care 2012
Adult Burn Resuscitation Formulae
(first 24 h)

    Formula                         Crystalloid             Colloid                     Other



    Evans (1952)                  1 ml/kg/%burn(N/S)       1 ml/kg/%burn             2000ml D5W
    Brooke (1953)                 1.5ml/kg/%burn(LR)      0.5 ml/kg/%burn            2000ml D5W
    Parkland (1968)                4 ml/kg/%burn(LR)             —                         —
    Modified Brooke (’71)          2 ml/kg/%burn(LR)             —                         —
    Hypertonic saline1                250 mEq Na/L               —                   Titrate to UO
    Modified hypertonic2              180 mEq Na/L               —                   Titrate to UO
                                    (first 8 h) then LR
    Dextran3                        LR (titrate to UO)         2 ml/kg/h              0.5 ml/kg/h
                                                          (first 8 h) then…              FFP

1Monafo   (1970) 2Warden (1992) 3Demling (1985)                  Bedside Critical Care 2012
FORMULAE
   Formulas should be regarded as a resuscitation
    guideline
   Lactated Ringer’s (Hartmans) solution most closely
    resembles normal body fluids, note NaCl ->
    hyperchloraemia
   The Parkland formula - renamed the Consensus
    formula - because it is the most widely used
    guideline
   4 mL/kg/% TBSA
   ½ in first 8 hrs rest over the next 16 hrs


                                      Bedside Critical Care 2012
RESUSCITATION
              Hypovolaemic State: 0-48 hours

Rapid fluid shifts                  Metabolic acidosis
Intense inflammatory
     response                       Protein loss
Capillary permeability              Oliguria
   3rd spacing                      Haemoconcentration
Fluid loss deep in wounds           Hyponatraemia
  circulating blood                 Hyperkalaemia
     volume




                                      Bedside Critical Care 2012
Consequences of fluid overload

                 Airway oedema
                 Compartment syndromes




                      Bedside Critical Care 2012
Dulhunty et al Burns 2008;34:1090-7

                          Bedside Critical Care 2012
ESCHAROTOMIES




           Bedside Critical Care 2012
ESCHAROTOMIES




 How not to do it!
                     Bedside Critical Care 2012
THE THREE MOST IMPORTANT ISSUES
IN BURNS CARE


 1. Debridement and get early coverage
 2. Debridement and get early coverage
 3. Debridement and get early coverage




                           Bedside Critical Care 2012
Coverage

 Xenograft (Pig skin)
 Allograft (cadarver skin)
 Biosynthetics and Synthetics (biobrane,
  integra)
 Cultured epithelial autograft




                             Bedside Critical Care 2012
Intensive Care Complications

   Ventilator associated pneumonia
   TACO/TRALI/ARDS
   CRBSI
   Pancreatitis
   Acalculous cholecystitis
   Ischaemic enterocolitis
   Gastritis
   Cardiomyopathy

                               Bedside Critical Care 2012
OTHER EARLY MANAGEMENT TIPS

  1.   Head position to reduce
       oedema
  2.   Ears: avoid
       pressure/chondritis
  3.   Graft tracheostomy site and
       central line sites first


                            Bedside Critical Care 2012
Nose: avoid notching from NG tube




                      Bedside Critical Care 2012
Eyes: avoid corneal ulceration




                      Bedside Critical Care 2012
EARLY ENTERAL FEEDING

 Repeated theatre trips don’t require
  cessation of feeds.
 “Do not stop feeds....” unless:


     a) prone position
     b) airway manipulation



                           Bedside Critical Care 2012
RBWH FEEDING PROTOCOL

    10-20% FTB/DPT: 125 - 145kJ/kg
     and 1.2 - 1.5g/kg protein

    >20% FTB/DPT: 145 - 160kJ/kg and
     20% energy as protein



                           Bedside Critical Care 2012
Principles of Burn Management:
Secondary survey




        The ultimate distracting injury

                                          Bedside Critical Care 2012
The ultimate distracting injury   Bedside Critical Care 2012
RBWH PEARLS
1.   Nebulised heparin for inhalation
     injury and to ??prevent VAP
2.   ETT wiring
3.   Feeding throughout
4.   1st area grafted is over trachea




                                 Bedside Critical Care 2012
Thank you
Thank you




             Bedside Critical Care 2012

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Holley on Burns

  • 1. Burns Anthony Holley Intensivist RBWH Bedside Critical Care 2012
  • 2. Acknowledgement Prof. Jeff Lipman Bedside Critical Care 2012
  • 3. Large tertiary ICU Only burns referral centre 40 months n = 158 Bedside Critical Care 2012
  • 4. Patient % Bu 10 15 20 25 30 35 40 0 5 rn :0 -9 Bu % rn :1 0- 19 % Bu rn :2 0- 29 Bu rn :3 0- 39 Bu rn :4 0- 49 Bu rn :5 Bedside Critical Care 2012 0- 59 Bu rn Burn % :6 0- n =158 69 Bu rn :7 0- 79 Body Surface Area Burn Distribution Bu rn :8 0- 89 Bu rn :9 Bu 0- rn 10 of 0 o ro ph ar ynx
  • 5. Mortality  8.22% mortality  But …….0.68% in those with intention “to cure” Bedside Critical Care 2012
  • 6. Wallace’s Rule of Nine Bedside Critical Care 2012
  • 8. First 24 HOURS A Airway assessment B Burn assessment C Circulation assessment Bedside Critical Care 2012
  • 9. AIRWAY 60% of flame facial burns will have inhalational injury Bedside Critical Care 2012
  • 10. Early Bronchoscopy Nebulised heparin for inhalation injury and to ??prevent VAP Bedside Critical Care 2012
  • 11. Alveolar Ridge/Maxillary Screws for ETT Fixation Bedside Critical Care 2012
  • 13. Adult Burn Resuscitation Formulae (first 24 h) Formula Crystalloid Colloid Other Evans (1952) 1 ml/kg/%burn(N/S) 1 ml/kg/%burn 2000ml D5W Brooke (1953) 1.5ml/kg/%burn(LR) 0.5 ml/kg/%burn 2000ml D5W Parkland (1968) 4 ml/kg/%burn(LR) — — Modified Brooke (’71) 2 ml/kg/%burn(LR) — — Hypertonic saline1 250 mEq Na/L — Titrate to UO Modified hypertonic2 180 mEq Na/L — Titrate to UO (first 8 h) then LR Dextran3 LR (titrate to UO) 2 ml/kg/h 0.5 ml/kg/h (first 8 h) then… FFP 1Monafo (1970) 2Warden (1992) 3Demling (1985) Bedside Critical Care 2012
  • 14. FORMULAE  Formulas should be regarded as a resuscitation guideline  Lactated Ringer’s (Hartmans) solution most closely resembles normal body fluids, note NaCl -> hyperchloraemia  The Parkland formula - renamed the Consensus formula - because it is the most widely used guideline  4 mL/kg/% TBSA  ½ in first 8 hrs rest over the next 16 hrs Bedside Critical Care 2012
  • 15. RESUSCITATION Hypovolaemic State: 0-48 hours Rapid fluid shifts Metabolic acidosis Intense inflammatory response Protein loss Capillary permeability Oliguria 3rd spacing Haemoconcentration Fluid loss deep in wounds Hyponatraemia circulating blood Hyperkalaemia volume Bedside Critical Care 2012
  • 16. Consequences of fluid overload Airway oedema Compartment syndromes Bedside Critical Care 2012
  • 17. Dulhunty et al Burns 2008;34:1090-7 Bedside Critical Care 2012
  • 18. ESCHAROTOMIES Bedside Critical Care 2012
  • 19. ESCHAROTOMIES How not to do it! Bedside Critical Care 2012
  • 20. THE THREE MOST IMPORTANT ISSUES IN BURNS CARE 1. Debridement and get early coverage 2. Debridement and get early coverage 3. Debridement and get early coverage Bedside Critical Care 2012
  • 21. Coverage  Xenograft (Pig skin)  Allograft (cadarver skin)  Biosynthetics and Synthetics (biobrane, integra)  Cultured epithelial autograft Bedside Critical Care 2012
  • 22. Intensive Care Complications  Ventilator associated pneumonia  TACO/TRALI/ARDS  CRBSI  Pancreatitis  Acalculous cholecystitis  Ischaemic enterocolitis  Gastritis  Cardiomyopathy Bedside Critical Care 2012
  • 23. OTHER EARLY MANAGEMENT TIPS 1. Head position to reduce oedema 2. Ears: avoid pressure/chondritis 3. Graft tracheostomy site and central line sites first Bedside Critical Care 2012
  • 24. Nose: avoid notching from NG tube Bedside Critical Care 2012
  • 25. Eyes: avoid corneal ulceration Bedside Critical Care 2012
  • 26. EARLY ENTERAL FEEDING  Repeated theatre trips don’t require cessation of feeds.  “Do not stop feeds....” unless: a) prone position b) airway manipulation Bedside Critical Care 2012
  • 27. RBWH FEEDING PROTOCOL  10-20% FTB/DPT: 125 - 145kJ/kg and 1.2 - 1.5g/kg protein  >20% FTB/DPT: 145 - 160kJ/kg and 20% energy as protein Bedside Critical Care 2012
  • 28. Principles of Burn Management: Secondary survey The ultimate distracting injury Bedside Critical Care 2012
  • 29. The ultimate distracting injury Bedside Critical Care 2012
  • 30. RBWH PEARLS 1. Nebulised heparin for inhalation injury and to ??prevent VAP 2. ETT wiring 3. Feeding throughout 4. 1st area grafted is over trachea Bedside Critical Care 2012
  • 31. Thank you Thank you Bedside Critical Care 2012