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First Quarter Fiscal 2013
Earnings Conference Call
                    March 6, 2013




                  www.nordion.com
Caution on Forward Looking Statements

This presentation contains forward-looking statements, within the meaning of applicable securities laws, including under
applicable Canadian securities laws and the “safe harbor” provisions of the United States Private Securities Litigation Reform Act
of 1995. These statements can be identified by expressions of belief, expectation or intention, as well as those statements that are
not historical fact. The words “may”, “will”, “could”, “should”, “would”, “outlook”, “believe”, “plan”, “anticipate”, “estimate”, “expect”
and similar words and expressions are also intended to identify forward-looking statements. Forward-looking statements are
necessarily based on estimates and assumptions made by us in light of our experience and our perception of historical trends,
current conditions and expected future developments, as well as other factors that we believe are appropriate in the
circumstances, but which are inherently subject to significant business, political, economic and competitive uncertainties and
contingencies. Known and unknown factors could cause actual results to differ materially from those projected in the forward-
looking statements. Accordingly, this presentation is subject to the disclaimer and qualified by the assumptions, qualifications and
risk factors referred to in our 2012 Annual Information Form (AIF).


We caution readers not to place undue reliance on the Company’s forward-looking statements, as a number of factors could
cause our actual results, performance or achievements to differ materially from any forward-looking statements. We do not
assume any obligation to update or revise any forward-looking statements, whether written or oral, that may be made from time to
time by us or on our behalf, except as required by applicable law.




                                                                                                                                             2
Non GAAP Information


To supplement the financial measures prepared in accordance with generally accepted accounting principles (GAAP), the
company uses non-GAAP financial measures such as adjusted net income and adjusted earnings per share. Non-GAAP financial
measures exclude certain items, such as restructuring charges and recovery, change in fair value of embedded derivatives, AECL
arbitration and legal fees, loss and gains on sales of investments, loss or gains on discontinued operations, and tax effects on
adjusted items. Management uses non-GAAP financial measures internally for strategic decision making, forecasting future
results and evaluating current performance. By disclosing non-GAAP financial measures, management intends to provide
investors with a meaningful, consistent comparison of the company's core operating results and trends for the periods presented.
Non-GAAP financial measures are not prepared in accordance with GAAP. Therefore, the information is not necessarily
comparable to other companies and should be considered as a supplement to, not a substitute for, or superior to, the
corresponding measures calculated in accordance with GAAP.




                                                                                                                                   3
First Quarter Fiscal 2013
                Earnings Conference Call
                                     Steve West
                               Chief Executive Officer




March 6, 2013                        www.nordion.com
Q1 2013 Results
        Targeted Therapies        Sterilization Technologies        Medical Isotopes


     Segmented Revenue                                         Segmented Earnings*
     (US$ millions)                                            (US$ millions)
60                                                        18

                                                          16
50
                                     16.4                 14
             16.1
                                                                        4.5
40                                                        12

                                                          10                                         3.5
30
                                                           8
             25.9                    25.2
                                                                        7.7
20                                                         6
                                                                                                     6.9
                                                           4
10
             11.0                    12.0                  2            3.1
                                                                                                     1.4
 0                                                         0
            2012                    2013                               2012                          2013
                             Q1                                                         Q1
                                                               * Excludes corporate segmented loss          5
Targeted Therapies: TheraSphere®


• $12.0 million in                                                                     • Annual growth in the
  revenue up 9% over                                                                     mid-teen percent




                                                                        2013 OUTLOOK
                            Q1 RESULTS
  Q1/12                                                                                  range
• Added 4 new sites in                                                                 • Growth in the
  the U.S. and 6 in                                                                      second half of fiscal
  EMEA                                                                                   2013 will be stronger
• Launched new global                                                                    than in the first half
  TheraSphere® website                                                                   of the year

• Initiated STOP-HCC
  clinical trial sites in
  Canada and Europe




                                               STRATEGY

                                         Build the Targeted Therapies
                                                   business.
                                                                                                            6
Specialty Isotopes: Sterilization Technologies


• $16.4 million revenue up                                                           • Maintain market-
  2% compared to Q1/12                                                                 leading position and




                                                                      2013 OUTLOOK
                                                                                       continue generating
                             Q1 RESULTS
• Cobalt revenue of $15.4
  million decreased 2%                                                                 high margins
  over Q1/12                                                                         • Strengthen
• $1.1 million in                                                                      relationships with
  Sterilization – Other                                                                current customers and
  revenue due to                                                                       enter into new and
  refurbishment work                                                                   emerging markets
  performed on existing                                                              • Selectively grow
  production irradiators                                                               gamma sterilization
                                                                                       sales over the long-
                                                                                       term



                                                STRATEGY

                                          Maintain cash generation
                                          and selectively invest in
                                                   growth.                                                    7
Specialty Isotopes: Medical Isotopes


• $25.2 million revenues,                                                                 • Maintain medical
  decreased 2.6%                                                                            isotopes sales by
                                                                                            working closely with




                                                                           2013 OUTLOOK
  compared with Q1
                            Q1 RESULTS
  fiscal 2012                                                                               existing customers to
                                                                                            bring additional value
• Reactor isotopes
  revenue was $20.4                                                                       • Explore strategic
  million, a decrease of                                                                    opportunities for
  $0.5 million or 3% over                                                                   cyclotron based
  Q1/12                                                                                     medical isotopes
• Contract manufacturing                                                                  • Assess opportunities
  revenues were up 6%                                                                       to obtain reliable and
  over Q1/12                                                                                long-term supply of
                                                                                            medical isotopes



                                                   STRATEGY


                                         Optimize the value of the business.
                                                                                                                8
First Quarter Fiscal 2013
                Earnings Conference Call
                                      Peter Dans
                                Chief Financial Officer




March 6, 2013                       www.nordion.com
Q1 2013 Financial Performance
       Q1 Segmented Revenue
           (US$ millions)
    60
    50
                16.1               16.4
    40
                                                     CONSOLIDATED RESULTS
    30
                25.9               25.2
    20                                               • Q1 revenue of $53.7 million; up 1% over
    10
                11.0               12.0
                                                       Q1/12
     0
                2012             2013                • GAAP net loss of $0.3 million
      Q1 Segmented Earnings*                         • Adjusted net income of $4.1 million down
           (US$ millions)
    20                                                 from $7.1 million over Q1/12
    15                                               • Non-GAAP EPS decreased to $0.07
                 4.5
                                                       compared with $0.11 non-GAAP EPS in
    10                             3.5
                 7.7
                                                       Q1/12
     5                             6.9
                                                     • Gross margin percentages were 52% in
                 3.1
     0                             1.4                 Q1/13
                2012             2013
    Targeted           Sterilization      Medical
    Therapies          Technologies       Isotopes

*EXCLUDES CORPORATE SEGEMENTED LOSS                                                               10
Business Segments
OVERVIEW & FINANCIAL
OUTLOOK – Targeted Therapies


•   Revenue grew 9% over Q1/12; segment earnings
    were down 54% due to higher spend in support of
    sales and marketing, and Phase III clinical trials


•   TheraSphere® revenue is expected to grow in the
    mid-teen percentage range in fiscal 2013
•   Phase III clinical trial spending is expected to be in
    the range of $6-8 million in fiscal 2013
•   Significant additional investments in fiscal 2013 to
    support TheraSphere® long-term global growth




                                                             11
Business Segments
OVERVIEW & FINANCIAL
OUTLOOK – Specialty Isotopes:
Sterilization Technologies
•   Revenue increased by 2%
•   Segment earnings were down 21% due to lower
    Co-60 sales volumes


•   In fiscal 2013, Sterilization Technologies
    revenue is expected to be approximately the
    same as in fiscal 2012; Co-60 revenue is
    expected to be similar to fiscal 2012
•   Fiscal 2013 quarterly profile of Co-60 revenue is
    expected to be similar to fiscal 2012




                                                        12
Business Segments
OVERVIEW & FINANCIAL
OUTLOOK – Specialty
Isotope: Medical Isotopes
•   Revenues of $25.2 million and earnings of
    $6.9 million in Q1 for Reactor, Cyclotron
    isotopes and contract manufacturing
•   Reactor isotopes revenue was $20.4
    million, a decrease of 3% compared to
    Q1/12


•   Total Medical Isotopes revenue is expected
    to decline in the mid-teen range in fiscal
    2013, compared to the original annual
    forecast of 20%




                                                 13
First Quarter Fiscal 2013
Earnings Conference Call
                    March 6, 2013




                  www.nordion.com

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Nordion First Quarter Fiscal 2013

  • 1. First Quarter Fiscal 2013 Earnings Conference Call March 6, 2013 www.nordion.com
  • 2. Caution on Forward Looking Statements This presentation contains forward-looking statements, within the meaning of applicable securities laws, including under applicable Canadian securities laws and the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. These statements can be identified by expressions of belief, expectation or intention, as well as those statements that are not historical fact. The words “may”, “will”, “could”, “should”, “would”, “outlook”, “believe”, “plan”, “anticipate”, “estimate”, “expect” and similar words and expressions are also intended to identify forward-looking statements. Forward-looking statements are necessarily based on estimates and assumptions made by us in light of our experience and our perception of historical trends, current conditions and expected future developments, as well as other factors that we believe are appropriate in the circumstances, but which are inherently subject to significant business, political, economic and competitive uncertainties and contingencies. Known and unknown factors could cause actual results to differ materially from those projected in the forward- looking statements. Accordingly, this presentation is subject to the disclaimer and qualified by the assumptions, qualifications and risk factors referred to in our 2012 Annual Information Form (AIF). We caution readers not to place undue reliance on the Company’s forward-looking statements, as a number of factors could cause our actual results, performance or achievements to differ materially from any forward-looking statements. We do not assume any obligation to update or revise any forward-looking statements, whether written or oral, that may be made from time to time by us or on our behalf, except as required by applicable law. 2
  • 3. Non GAAP Information To supplement the financial measures prepared in accordance with generally accepted accounting principles (GAAP), the company uses non-GAAP financial measures such as adjusted net income and adjusted earnings per share. Non-GAAP financial measures exclude certain items, such as restructuring charges and recovery, change in fair value of embedded derivatives, AECL arbitration and legal fees, loss and gains on sales of investments, loss or gains on discontinued operations, and tax effects on adjusted items. Management uses non-GAAP financial measures internally for strategic decision making, forecasting future results and evaluating current performance. By disclosing non-GAAP financial measures, management intends to provide investors with a meaningful, consistent comparison of the company's core operating results and trends for the periods presented. Non-GAAP financial measures are not prepared in accordance with GAAP. Therefore, the information is not necessarily comparable to other companies and should be considered as a supplement to, not a substitute for, or superior to, the corresponding measures calculated in accordance with GAAP. 3
  • 4. First Quarter Fiscal 2013 Earnings Conference Call Steve West Chief Executive Officer March 6, 2013 www.nordion.com
  • 5. Q1 2013 Results Targeted Therapies Sterilization Technologies Medical Isotopes Segmented Revenue Segmented Earnings* (US$ millions) (US$ millions) 60 18 16 50 16.4 14 16.1 4.5 40 12 10 3.5 30 8 25.9 25.2 7.7 20 6 6.9 4 10 11.0 12.0 2 3.1 1.4 0 0 2012 2013 2012 2013 Q1 Q1 * Excludes corporate segmented loss 5
  • 6. Targeted Therapies: TheraSphere® • $12.0 million in • Annual growth in the revenue up 9% over mid-teen percent 2013 OUTLOOK Q1 RESULTS Q1/12 range • Added 4 new sites in • Growth in the the U.S. and 6 in second half of fiscal EMEA 2013 will be stronger • Launched new global than in the first half TheraSphere® website of the year • Initiated STOP-HCC clinical trial sites in Canada and Europe STRATEGY Build the Targeted Therapies business. 6
  • 7. Specialty Isotopes: Sterilization Technologies • $16.4 million revenue up • Maintain market- 2% compared to Q1/12 leading position and 2013 OUTLOOK continue generating Q1 RESULTS • Cobalt revenue of $15.4 million decreased 2% high margins over Q1/12 • Strengthen • $1.1 million in relationships with Sterilization – Other current customers and revenue due to enter into new and refurbishment work emerging markets performed on existing • Selectively grow production irradiators gamma sterilization sales over the long- term STRATEGY Maintain cash generation and selectively invest in growth. 7
  • 8. Specialty Isotopes: Medical Isotopes • $25.2 million revenues, • Maintain medical decreased 2.6% isotopes sales by working closely with 2013 OUTLOOK compared with Q1 Q1 RESULTS fiscal 2012 existing customers to bring additional value • Reactor isotopes revenue was $20.4 • Explore strategic million, a decrease of opportunities for $0.5 million or 3% over cyclotron based Q1/12 medical isotopes • Contract manufacturing • Assess opportunities revenues were up 6% to obtain reliable and over Q1/12 long-term supply of medical isotopes STRATEGY Optimize the value of the business. 8
  • 9. First Quarter Fiscal 2013 Earnings Conference Call Peter Dans Chief Financial Officer March 6, 2013 www.nordion.com
  • 10. Q1 2013 Financial Performance Q1 Segmented Revenue (US$ millions) 60 50 16.1 16.4 40 CONSOLIDATED RESULTS 30 25.9 25.2 20 • Q1 revenue of $53.7 million; up 1% over 10 11.0 12.0 Q1/12 0 2012 2013 • GAAP net loss of $0.3 million Q1 Segmented Earnings* • Adjusted net income of $4.1 million down (US$ millions) 20 from $7.1 million over Q1/12 15 • Non-GAAP EPS decreased to $0.07 4.5 compared with $0.11 non-GAAP EPS in 10 3.5 7.7 Q1/12 5 6.9 • Gross margin percentages were 52% in 3.1 0 1.4 Q1/13 2012 2013 Targeted Sterilization Medical Therapies Technologies Isotopes *EXCLUDES CORPORATE SEGEMENTED LOSS 10
  • 11. Business Segments OVERVIEW & FINANCIAL OUTLOOK – Targeted Therapies • Revenue grew 9% over Q1/12; segment earnings were down 54% due to higher spend in support of sales and marketing, and Phase III clinical trials • TheraSphere® revenue is expected to grow in the mid-teen percentage range in fiscal 2013 • Phase III clinical trial spending is expected to be in the range of $6-8 million in fiscal 2013 • Significant additional investments in fiscal 2013 to support TheraSphere® long-term global growth 11
  • 12. Business Segments OVERVIEW & FINANCIAL OUTLOOK – Specialty Isotopes: Sterilization Technologies • Revenue increased by 2% • Segment earnings were down 21% due to lower Co-60 sales volumes • In fiscal 2013, Sterilization Technologies revenue is expected to be approximately the same as in fiscal 2012; Co-60 revenue is expected to be similar to fiscal 2012 • Fiscal 2013 quarterly profile of Co-60 revenue is expected to be similar to fiscal 2012 12
  • 13. Business Segments OVERVIEW & FINANCIAL OUTLOOK – Specialty Isotope: Medical Isotopes • Revenues of $25.2 million and earnings of $6.9 million in Q1 for Reactor, Cyclotron isotopes and contract manufacturing • Reactor isotopes revenue was $20.4 million, a decrease of 3% compared to Q1/12 • Total Medical Isotopes revenue is expected to decline in the mid-teen range in fiscal 2013, compared to the original annual forecast of 20% 13
  • 14. First Quarter Fiscal 2013 Earnings Conference Call March 6, 2013 www.nordion.com