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NORDION
Corporate Presentation
March 7, 2014

www.nordion.com
Caution on Forward Looking Statements
This presentation contains forward-looking statements, within the meaning of applicable securities laws, including under
applicable Canadian securities laws and the “safe harbor” provisions of the United States Private Securities Litigation Reform Act
of 1995. These statements can be identified by expressions of belief, expectation or intention, as well as those statements that are
not historical fact. The words “may”, “will”, “could”, “should”, “would”, “outlook”, “believe”, “plan”, “anticipate”, “estimate”, “expect”
and similar words and expressions are also intended to identify forward-looking statements. Forward-looking statements are
necessarily based on estimates and assumptions made by us in light of our experience and our perception of historical trends,
current conditions and expected future developments, as well as other factors that we believe are appropriate in the
circumstances, but which are inherently subject to significant business, political, economic and competitive uncertainties and
contingencies. Known and unknown factors could cause actual results to differ materially from those projected in the forwardlooking statements. Accordingly, this presentation is subject to the disclaimer and qualified by the assumptions, qualifications and
risk factors referred to in our 2013 Annual Information Form (AIF).
We caution readers not to place undue reliance on the Company’s forward-looking statements, as a number of factors could
cause our actual results, performance or achievements to differ materially from any forward-looking statements. We do not
assume any obligation to update or revise any forward-looking statements, whether written or oral, that may be made from time to
time by us or on our behalf, except as required by applicable law.

2
About Nordion
Nordion is a health science company that
provides market-leading products used for
the prevention, diagnosis and treatment of
disease.
Delivering quality products to our global
customers for more than 60 years, our product
portfolio includes:
• Sterilization Technologies
• Medical Isotopes

3
A Global Company
F2013 REVENUES BY REGION - $232.8M*

64%
UNITED STATES

23%
5%
CANADA

ROW

8%
EUROPE

APPROXIMATELY

AROUND

SUPPLY OVER

ACROSS MORE THAN

400 EMPLOYEES

30 PRODUCTS

500 CUSTOMERS

40 COUNTRIES
4

*Revenues and regional breakdown include Targeted Therapies business, which was divested in July 2013 to BTG plc.
2013 Financial Highlights
Revenue Trend (US$ Millions)

Sterilization Technologies

Medical Isotopes

Targeted Therapies*

300
250

42.6
48.5

36.3

101.0

100.3

108.7

95.4

96.1

2011

2012

2013

200
122.8
150
100
50
0

* In July 2013, Nordion divested its Targeted Therapies business to BTG plc

5
2013 Financial Highlights
Segment Earnings Trend (US$ Millions)

Sterilization Technologies

Medical Isotopes

Targeted Therapies*

120
100
12.7

80
60

14.1
38.3

3.0
29.4

25.9

40
20

46.1

39.0

35.3

2012

2013

0
2011

Excludes corporate segmented loss
* In July 2013, Nordion divested its Targeted Therapies business to BTG plc

6
Q1 2014 Results
Sterilization Technologies

Medical Isotopes

Targeted Therapies

Segmented Revenue

Segmented Earnings*

(US$ millions)

(US$ millions)

80.0

35.0

70.0

30.0

60.0
50.0

25.0
12.0

51.7

20.0

25.1

40.0
15.0
30.0

25.2

10.0

20.0

1.4

6.9

10.0

19.2

16.4

5.0

7.1
3.5

0.0

0.0
2013

Q1

2014

2013

Q1

* Excludes corporate segment

2014
7
Q1 2014 Timeline

Nordion participates at the
2013 International Meeting on
Radiation Process in
Shanghai, China

Nordion publishes its fiscal
2013 Annual Report and
files associated disclosure
documents.

November

January

Q1 2014
Nordion posted its 2012
Annual Report on Toxic
Substance Reduction

December

Nordion signs customer
contracts to supply
strontium-82 and cobalt.

January

8
Leading Products in Global Markets
STERILIZATION
TECHNOLOGIES

MEDICAL
ISOTOPES

Maintain Sterilization business;
selectively invest in growth:
• Geographic expansion
• New applications

Optimize Medical Isotopes business
• Secure long-term supply
• Maintain customer relationships

POTENTIAL >

Approximately 40% of single-use medical
products worldwide are sterilized using
gamma sterilization technologies

Over 10,000 hospitals worldwide use
radioisotopes in medical procedures with
about 90% being for diagnosis.

ADVANTAGE >

• Global leader in cobalt-60
• Significant barriers to entry
• Solid cash flow and gross margins
• Recurring revenue base

• A global provider in
processing, packaging, & delivery
• Extensive regulatory expertise and
logistics & distribution network

PRIORITY >

9
Specialty Isotopes: Sterilization Technologies
•

Gamma sterilization is focused on
the prevention of disease

•

Co-60 is used to sterilize medical devices,
instruments and supplies and food

•

Customers of Co-60 include
contract sterilization service providers
and medical device and product manufacturers

•

The Nordion Gamma Centre of Excellence is a
world class applied research and specialty gamma
processing facility to promote and expand the use
of gamma globally

•

Nordion manufactures Co-60 irradiation sources,
and designs, constructs and maintains commercial
gamma sterilization systems

10
Sterilization Market Segmentation

MARKET MIX

80%
MEDICAL & SURGICAL

PRODUCTS

•
•
•
•

Syringes
Catheters
Drapes, gowns
Sutures, gloves

10%

•
•
•
•

Stents
Patches
Tissue
Regen medicine

10%
10%

•
•
•
•

Fruits & vegetables
Spices
Meat and poultry
Ready To Eat (RTE)

BIO-ACTIVE DEVICES

FOOD SAFETY

DRIVERS

+ Aging population
+ Min invasive surgery
+ Smaller devices
+ Material

+ Aging population
+ Enhance devices
+ Leverage drugs
+ Stem cell research

+ FDA labeling
+ USDA FEA
+ Food safety concerns

11
Specialty Isotopes: Medical Isotopes
•

Medical isotopes are used to prevent, diagnose
and treat disease

•

Main isotope supply sources
are nuclear reactors and cyclotrons

•

Primary product is Mo-99, which decays for use in
Technetium-99 (Tc-99m) generators, used in
imaging to diagnose heart disease and cancers

•

Other Key Reactor Isotopes:
–
–

Iodine-131 (I-131), used to treat hyperthyroidism, thyroid cancer and
non-Hodgkin’s lymphoma;

–

Iodine-125 (I-125), used to treat prostate cancer;

–

•

Xenon-133 (Xe-133), used in lung scans;

Yttrium-90 (Y-90), used to treat liver cancer.

Key Cyclotron Isotopes:
–

Iodine-123 (I-123), used to diagnose thyroid disease;

–

Strontium-82 (Sr-82), used to manufacture rubidium-82 generators,
which are used in imaging to diagnose heart disease

–

Thallium-201 (Tl-201), used to diagnose and assess risk of coronary
artery heart disease;

–

Palladium-103 (Pd-103), used to treat prostate cancer;

–

Indium-111 (In-111) and Gallium-67 (Ga-67) (both used to diagnose
infection and cancer) at our Vancouver facilities
12
Medical Isotopes (Mo-99) Supply Chain

NUCLEAR
REACTORS

RADIOPHARMACEUTICAL
MANUFACTURERS

RADIOPHARMACIES
AND HOSPITALS

PHYSICIANS
AND PATIENTS

Irradiation of
HEU targets to
produce crude
isotopes

•
•

MEDICAL ISOTOPE
PROCESSORS

Purification of
Mo-99 and
distribution to global
radiopharmaceutical
manufacturers

Tc-99m
Generator
manufacturing
and distribution to
radiopharmacies

Unit dose
compounding and
distribution to
hospital/departments

Critical physiological
diagnosis enabling
informed therapeutic
decisions

Established, reliable facilities providing high-quality isotopes to global customers
Specialty skills in operations, regulatory affairs and global logistics

13
Nordion Environmental, Health,
and Safety (EH&S) Program
• Creating a workplace that enriches
the health and well-being of Nordion
employees

• Demonstrating Environmental, Health,
and Safety (EH&S) regulatory excellence
• Improving EH&S performance –
continually

• Managing EH&S with excellence
Recipient of Canada’s Safest
Employers - Gold level award
October, 2013
14
Nordion Environmental, Health,
and Safety (EH&S) Program
•

Implementing measures in the design and operation of all of
our facilities to keep radiation dose received by workers and
the public ALARA (as low as reasonably achievable)

•

Implementing an ISO 14001-based environmental
management (EMS) system at our Ottawa site

•

Establishing EH&S objectives and targets annually
to continually improve our performance

•

Maintaining - and building on - a comprehensive training
program for employees and contractors

•

Engraining EH&S excellence into the Nordion culture

•

Investing in a world class approach to EH&S

ISO 14001: 2004 certified
Recipient of the Government of Canada 2007 ENERGY STAR ÂŽ Market Transformation Award
Practitioner of LeanSigma, a methodology used to continually improve processes
Recipient of an unprecedented ten-year license renewal from the Canadian Nuclear Safety Commission (CNSC)

15
In the Community

Ride the Rideau
Sponsor of Ride the Rideau since its inauguration in 2010, Nordion has helped to raise
over $6.4 million for cancer research at The Ottawa Hospital Research Institute.

Other Programs:
• Employee Giving Program - Nordion
makes donations to not-for-profit
organizations nominated by employees
• Proud sponsor of the Gala for Research,
an annual black-tie event to support
the Ottawa Hospital Research Institute,
the research arm of The Ottawa Hospital

16
Business Outlook
The talented, dedicated and
resilient people that make
up Nordion share a single
purpose:
• Maintain a global leadership
position in our key markets
• Build value for shareholders
through the execution of our
strategic priorities

• Be a trusted, world-class provider
of healthcare products to our
customers

17
Find out more at

www.nordion.com
Follow us at

http://twitter.com/NordionInc

www.nordion.com

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Nordion corporate presentation_2014_q1

  • 2. Caution on Forward Looking Statements This presentation contains forward-looking statements, within the meaning of applicable securities laws, including under applicable Canadian securities laws and the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. These statements can be identified by expressions of belief, expectation or intention, as well as those statements that are not historical fact. The words “may”, “will”, “could”, “should”, “would”, “outlook”, “believe”, “plan”, “anticipate”, “estimate”, “expect” and similar words and expressions are also intended to identify forward-looking statements. Forward-looking statements are necessarily based on estimates and assumptions made by us in light of our experience and our perception of historical trends, current conditions and expected future developments, as well as other factors that we believe are appropriate in the circumstances, but which are inherently subject to significant business, political, economic and competitive uncertainties and contingencies. Known and unknown factors could cause actual results to differ materially from those projected in the forwardlooking statements. Accordingly, this presentation is subject to the disclaimer and qualified by the assumptions, qualifications and risk factors referred to in our 2013 Annual Information Form (AIF). We caution readers not to place undue reliance on the Company’s forward-looking statements, as a number of factors could cause our actual results, performance or achievements to differ materially from any forward-looking statements. We do not assume any obligation to update or revise any forward-looking statements, whether written or oral, that may be made from time to time by us or on our behalf, except as required by applicable law. 2
  • 3. About Nordion Nordion is a health science company that provides market-leading products used for the prevention, diagnosis and treatment of disease. Delivering quality products to our global customers for more than 60 years, our product portfolio includes: • Sterilization Technologies • Medical Isotopes 3
  • 4. A Global Company F2013 REVENUES BY REGION - $232.8M* 64% UNITED STATES 23% 5% CANADA ROW 8% EUROPE APPROXIMATELY AROUND SUPPLY OVER ACROSS MORE THAN 400 EMPLOYEES 30 PRODUCTS 500 CUSTOMERS 40 COUNTRIES 4 *Revenues and regional breakdown include Targeted Therapies business, which was divested in July 2013 to BTG plc.
  • 5. 2013 Financial Highlights Revenue Trend (US$ Millions) Sterilization Technologies Medical Isotopes Targeted Therapies* 300 250 42.6 48.5 36.3 101.0 100.3 108.7 95.4 96.1 2011 2012 2013 200 122.8 150 100 50 0 * In July 2013, Nordion divested its Targeted Therapies business to BTG plc 5
  • 6. 2013 Financial Highlights Segment Earnings Trend (US$ Millions) Sterilization Technologies Medical Isotopes Targeted Therapies* 120 100 12.7 80 60 14.1 38.3 3.0 29.4 25.9 40 20 46.1 39.0 35.3 2012 2013 0 2011 Excludes corporate segmented loss * In July 2013, Nordion divested its Targeted Therapies business to BTG plc 6
  • 7. Q1 2014 Results Sterilization Technologies Medical Isotopes Targeted Therapies Segmented Revenue Segmented Earnings* (US$ millions) (US$ millions) 80.0 35.0 70.0 30.0 60.0 50.0 25.0 12.0 51.7 20.0 25.1 40.0 15.0 30.0 25.2 10.0 20.0 1.4 6.9 10.0 19.2 16.4 5.0 7.1 3.5 0.0 0.0 2013 Q1 2014 2013 Q1 * Excludes corporate segment 2014 7
  • 8. Q1 2014 Timeline Nordion participates at the 2013 International Meeting on Radiation Process in Shanghai, China Nordion publishes its fiscal 2013 Annual Report and files associated disclosure documents. November January Q1 2014 Nordion posted its 2012 Annual Report on Toxic Substance Reduction December Nordion signs customer contracts to supply strontium-82 and cobalt. January 8
  • 9. Leading Products in Global Markets STERILIZATION TECHNOLOGIES MEDICAL ISOTOPES Maintain Sterilization business; selectively invest in growth: • Geographic expansion • New applications Optimize Medical Isotopes business • Secure long-term supply • Maintain customer relationships POTENTIAL > Approximately 40% of single-use medical products worldwide are sterilized using gamma sterilization technologies Over 10,000 hospitals worldwide use radioisotopes in medical procedures with about 90% being for diagnosis. ADVANTAGE > • Global leader in cobalt-60 • Significant barriers to entry • Solid cash flow and gross margins • Recurring revenue base • A global provider in processing, packaging, & delivery • Extensive regulatory expertise and logistics & distribution network PRIORITY > 9
  • 10. Specialty Isotopes: Sterilization Technologies • Gamma sterilization is focused on the prevention of disease • Co-60 is used to sterilize medical devices, instruments and supplies and food • Customers of Co-60 include contract sterilization service providers and medical device and product manufacturers • The Nordion Gamma Centre of Excellence is a world class applied research and specialty gamma processing facility to promote and expand the use of gamma globally • Nordion manufactures Co-60 irradiation sources, and designs, constructs and maintains commercial gamma sterilization systems 10
  • 11. Sterilization Market Segmentation MARKET MIX 80% MEDICAL & SURGICAL PRODUCTS • • • • Syringes Catheters Drapes, gowns Sutures, gloves 10% • • • • Stents Patches Tissue Regen medicine 10% 10% • • • • Fruits & vegetables Spices Meat and poultry Ready To Eat (RTE) BIO-ACTIVE DEVICES FOOD SAFETY DRIVERS + Aging population + Min invasive surgery + Smaller devices + Material + Aging population + Enhance devices + Leverage drugs + Stem cell research + FDA labeling + USDA FEA + Food safety concerns 11
  • 12. Specialty Isotopes: Medical Isotopes • Medical isotopes are used to prevent, diagnose and treat disease • Main isotope supply sources are nuclear reactors and cyclotrons • Primary product is Mo-99, which decays for use in Technetium-99 (Tc-99m) generators, used in imaging to diagnose heart disease and cancers • Other Key Reactor Isotopes: – – Iodine-131 (I-131), used to treat hyperthyroidism, thyroid cancer and non-Hodgkin’s lymphoma; – Iodine-125 (I-125), used to treat prostate cancer; – • Xenon-133 (Xe-133), used in lung scans; Yttrium-90 (Y-90), used to treat liver cancer. Key Cyclotron Isotopes: – Iodine-123 (I-123), used to diagnose thyroid disease; – Strontium-82 (Sr-82), used to manufacture rubidium-82 generators, which are used in imaging to diagnose heart disease – Thallium-201 (Tl-201), used to diagnose and assess risk of coronary artery heart disease; – Palladium-103 (Pd-103), used to treat prostate cancer; – Indium-111 (In-111) and Gallium-67 (Ga-67) (both used to diagnose infection and cancer) at our Vancouver facilities 12
  • 13. Medical Isotopes (Mo-99) Supply Chain NUCLEAR REACTORS RADIOPHARMACEUTICAL MANUFACTURERS RADIOPHARMACIES AND HOSPITALS PHYSICIANS AND PATIENTS Irradiation of HEU targets to produce crude isotopes • • MEDICAL ISOTOPE PROCESSORS Purification of Mo-99 and distribution to global radiopharmaceutical manufacturers Tc-99m Generator manufacturing and distribution to radiopharmacies Unit dose compounding and distribution to hospital/departments Critical physiological diagnosis enabling informed therapeutic decisions Established, reliable facilities providing high-quality isotopes to global customers Specialty skills in operations, regulatory affairs and global logistics 13
  • 14. Nordion Environmental, Health, and Safety (EH&S) Program • Creating a workplace that enriches the health and well-being of Nordion employees • Demonstrating Environmental, Health, and Safety (EH&S) regulatory excellence • Improving EH&S performance – continually • Managing EH&S with excellence Recipient of Canada’s Safest Employers - Gold level award October, 2013 14
  • 15. Nordion Environmental, Health, and Safety (EH&S) Program • Implementing measures in the design and operation of all of our facilities to keep radiation dose received by workers and the public ALARA (as low as reasonably achievable) • Implementing an ISO 14001-based environmental management (EMS) system at our Ottawa site • Establishing EH&S objectives and targets annually to continually improve our performance • Maintaining - and building on - a comprehensive training program for employees and contractors • Engraining EH&S excellence into the Nordion culture • Investing in a world class approach to EH&S ISO 14001: 2004 certified Recipient of the Government of Canada 2007 ENERGY STAR ÂŽ Market Transformation Award Practitioner of LeanSigma, a methodology used to continually improve processes Recipient of an unprecedented ten-year license renewal from the Canadian Nuclear Safety Commission (CNSC) 15
  • 16. In the Community Ride the Rideau Sponsor of Ride the Rideau since its inauguration in 2010, Nordion has helped to raise over $6.4 million for cancer research at The Ottawa Hospital Research Institute. Other Programs: • Employee Giving Program - Nordion makes donations to not-for-profit organizations nominated by employees • Proud sponsor of the Gala for Research, an annual black-tie event to support the Ottawa Hospital Research Institute, the research arm of The Ottawa Hospital 16
  • 17. Business Outlook The talented, dedicated and resilient people that make up Nordion share a single purpose: • Maintain a global leadership position in our key markets • Build value for shareholders through the execution of our strategic priorities • Be a trusted, world-class provider of healthcare products to our customers 17
  • 18. Find out more at www.nordion.com Follow us at http://twitter.com/NordionInc www.nordion.com