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BIOLOGY FORM 4 
CHAPTER 7 
RESPIRATION PART 1
Objectives 
7.1 Understanding the respiratory processes in energy 
production 
7.2 Analysing the respiratory structure and breathing 
mechanism in human and animal 
7.3 Understanding the concept of gaseous exchange 
across the respiratory surfaces and transport of 
gases in human 
7.4 Understanding the regulatory mechanism in 
respiration 
7.5 Realising the importance of maintaining a healthy 
respiratory system 
7.6 Understanding respiration in plants
7.1 
Understanding the respiratory 
processes in energy production
The respiratory gases 
• are:
cells need to: 
obtain O2 
WHY? 
eliminate CO2 
WHY?
cells need to: 
obtain O2 to 
produce ATP 
eliminate CO2 
to prevent 
toxic effects
What is respiration?? 
Process of obtaining oxygen 
and delivering it to the cells 
for cellular respiration 
and 
removing carbon dioxide 
produced by cells
Respiration 
External Respiration 
(Breathing) 
Internal Respiration 
(Cellular respiration) 
Aerobic 
Respiration 
Anaerobic 
Respiration 
2 stages 
2 types
External respiration 
(Breathing) 
• The exchange of respiratory gases (oxygen 
and carbon dioxide) between the body and 
the environment
Internal respiration 
( Cellular Respiration) 
• A metabolic process 
• which occurs in cells, 
• involves oxidation of organic molecules(food) 
• to produce energy (in the form of ATP) 
• Controlled by enzymes 
Two types : 
1. Aerobic respiration 
2. Anaerobic respiration
The main substrate to 
produce energy is 
GLUCOSE
Fuels are used in sequence 
Muscle 
Glucose is stored here 
as glycogen and is used 
when the body is 
working harder. 
1. CARBOHYDRATES 
2. FATS 
3. PROTEINS 
Liver 
Here some of the 
glucose is stored as 
glycogen and used to 
maintain blood sugar 
levels. 
Used when the 
carbohydrates are 
exhausted. Are 
first converted to 
glycerol and fatty 
acids 
Used when 
carbohydrates 
and fats have 
been used up as 
during prolonged 
starvation
ENERGY
How does body convert 
energy stored in food 
 energy for body use?
Through Cellular 
Respiration 
 Cellular Respiration is the oxidation of food (glucose) 
with the release of energy in living cells 
2 Types of Cellular Respiration: 
Aerobic and Anaerobic respiration
Aerobic respiration 
• Require oxygen 
• Glucose is completely oxidised 
• to produce 36 - 38 molecules of ATP 
/ 2898 kJ energy (high energy) 
• Takes place in the cytoplasm and mitochondria 
C6H12O6 + 6O2 
6CO2 + 6H2O + Energy (2898 kJ)
Anaerobic respiration 
• Without oxygen 
• Glucose is not completely broken down 
• Releases only 2 ATP (low energy) 
• Takes place in the cytoplasm 
• Eg. In human muscles, yeast, microbes in 
mud 
Yeast: 
Glucose  Carbon dioxide + ethanol + 210 kJ energy 
Muscle: 
Glucose  Lactic acid + 150 kJ energy
Some microbes living in the mud… low oxygen 
level … 
Respire ananerobically!
• Respiration without oxygen.
YYeEaAsSTt!
Anaerobic respiration in yeast 
•Yeast normally respires aerobically 
•Anaerobic respiration in yeast produces 
ethanol, carbon dioxide and energy
IN YEAST 
• Anaerobic respiration in yeast also 
known as fermentation 
C6H12O6 
2CO2 + 2C2H5OH + Energy(210kJ) 
ethanol 
Zymase 
• Ethanol can be used in wine & beer production 
• CO2 released causes the dough to rise (to make bread)
Alcoholic Fermentation 
C6H12O6 
 2C2H5OH + 2CO2 + energy 
glucose ethanol carbon 
dioxide 
• Occurs in yeast cells.
Dough rising 36 
The yeast is mixed 
with the dough 
After 1 hour in a warm 
place the dough has 
risen as a result of the 
carbon dioxide 
produced by the yeast
Anaerobic Respiration 
Glucose (with baker’s yeast) 
 Carbon dioxide + ethanol + little energy (210kJ) 
The ‘holes’ in the 
bread are made by 
the carbon dioxide 
bubbles. 
This gives the bread a 
‘light’ texture
Anaerobic respiration in humans! 
Highly intensive exercise 
Glucose  Lactic acid + energy
Anaerobic Respiration in the Muscles 
1. Vigorous muscle movement  increase rate of aerobic 
respiration to release more energy. 
Glucose + oxygen  Carbon dioxide + water + 2898kJ 
energy
What happens when you need more 
energy but there’s not enough oxygen?
Muscle cells (anaerobic respiration) 
• Prolonged physical activity 
- O2 supplied not enough 
- O2 needed > O2 supplied 
- muscle cells undergo anaerobic respiration 
• Muscles in state of O2 deficiency  O2 debt 
occurred 
• Oxygen debt : muscle cells produce ATP 
without oxygen
• Glucose molecules break down partially into 
Lactic Acid 
C6H12O6 2C3H6O3 + Energy (150kJ) 
lactic acid 
• Energy low because much of energy still trapped 
within molecules of lactic acid. 
• High concentration of lactic acid 
may cause muscular cramp and 
fatigue, tiredness
“Repaying” oxygen debt 
• After the activity the person need to breathe 
deeply and rapidly to inhale more O2 
- O2 is used to oxidise accumulated lactic acid 
to form CO2 and H2O (occur mainly in liver) 
Lactic acid + O2 CO2 + H2O + energy 
Remaining lactic acid converted into glycogen and 
stored in muscle cells
Oxygen Debt 
Question: How do sprinters pay back 
their oxygen debt at the end of a race? 
Answer: Sprinters will continue to breathe more deeply and rapidly for a 
number of minutes at the end of their race. This will enable them to pay 
back the oxygen debt, and allow lactic acid levels to fall.
Oxygen debt 
The amount of oxygen needed to remove lactic acid from 
muscle cells is called oxygen debt 
The time taken to remove all the lactic acid is called the 
recovery period
• Oxygen debt is paid off when all of 
lactic acid is removed (increasing 
breathing rate after vigorous activity)
Energy needed for vigorous 
exercise 
Glucose + oxygen  Carbon dioxide + water + 2898 kJ 
Glucose + Oxygen  Lactic acid + 150 kJ 
Total amount of energy 
needed for vigorous muscular 
contractions 
Aerobic respiration 
Anaerobic respiration
Why aerobic respiration 
produced more energy than 
anaerobic respiration???
Why are virtually all organisms aerobes? 
More ATP 
released in 
aerobic rather 
than in 
anaerobic 
respiration
Aerobic and Anaerobic 
Respiration 
RESPIRATION 
Anaerobic 
Respiration 
Alcoholic 
Fermentation 
Lactic Acid 
Production 
Aerobic 
Respiration 
C6H12O6 + 6O2 
 6CO2 + 6H2O + energy 
glucose oxygen carbon water 
dioxide 
C6H12O6 
 2C2H5OH + 2CO2 + energy 
glucose ethanol carbon 
dioxide 
• Occurs in yeast cells. 
C6H12O6 
 2C3H6O3 + energy 
glucose lactic 
acid 
• Occurs in muscle cells. 
• Leads to fatigue.
 SIMILARITIES 
 Cellular respiration 
 Involve the breakdown of glucose 
 Produces energy 
 Are catalyzed by enzymes 
 Occurs in animal and plants
Differences between Aerobic Respiration & 
Anaerobic Respiration 
Aerobic Respiration Items Anaerobic 
Respiration 
Almost every living 
cells 
Work in Certain plant, yeast, 
bacteria and muscle 
Required Oxygen requirement Not required 
Complete oxidation Oxidation of glucose Incomplete 
oxidation 
CO2, Water and 
Energy 
Product Yeast 
CO2, Ethanol and 
Energy 
Muscle 
Lactic acid and 
Energy
Differences between Aerobic Respiration & 
Anaerobic Respiration 
Aerobic Respiration Items Anaerobic Respiration 
Large amount Energy released Small amount 
Mitochondria and 
Site Cytoplasm 
cytoplasm 
C6H12O6 + 6O2 
Glucose 
↓ 
6CO2 + H20 + 2898 kJ 
Energy 
Chemical Equation In Yeast: 
C6H12O6 
Glucose 
↓ 
2CO2 + 2C2H5OH + 210 kJ 
Ethanol Energy 
In Muscle cells: 
C6H12O6 
Glucose 
↓ 
2C3H6O3 + 150kJ 
Lactic acid Energy 
38 molecules Number of ATP molecules 
produced 
2 molecules
• This apparatus can be used to investigate how small 
living organisms respire such as woodlice, maggots or 
germinating seeds. 
Living organisms 
Gauze 
Hydrogen carbonate indicator – This will change 
colour from red to yellow when the carbon 
dioxide level increases due to respiration.
The germinating seeds are respiring and therefore releasing heat. The boiled 
seeds have been killed and are therefore not respiring anymore. 
Cotton wool 
Thermometer 
Thermal flask
7.2 
Analysing the respiratory structure 
and 
breathing mechanism in human 
and animal
 LEARNING OUTCOMES: 
 State the respiratory structures in 
humans and some animals 
 Describe the characteristics of 
respiratory surfaces in humans and 
other organisms 
 Describe breathing mechanisms in 
human and other organisms 
 Compare and contrast the human 
respiratory system with other 
organisms
Gaseous exchange: 
is the exchange of oxygen and carbon 
dioxide between the environment and the 
organism 
takes place in all organisms by diffusion
A ‘respiratory surface’ is the: 
area where gaseous exchange 
actually takes place
Adaptations of respiratory structures 
(General characteristics) 
1. Moist – easy for gases to dissolve 
before diffuse 
2. Thin – allow rapid diffusion of gases 
3. Large surface area – efficient gaseous 
exchange 
4. Covered by a network of blood 
capillaries – efficient exchange and 
transport of respiratory gases
Organisms acquire their oxygen: 
direct from the 
atmosphere 
dissolved 
in water 
1 2
oxygen 
Unicellular organisms 
carbon dioxide 
maximum 
distance 
is 0.1 mm 
The distance is so small that diffusion is rapid 
enough for the cell’s needs 
Amoeba
Protozoa – Unicellular Organism 
Oxygen 
nutrients 
Carbon 
dioxide 
Waste 
products 
The respiratory surface of an unicellular 
organism is through plasma membrane
Adaptations 
1. Small Size 
 large surface area to volume (TSA/V) ratio 
 rate of diffusion increases 
2. Wet surroundings 
 plasma membrane constantly moist 
 gases easily dissolve and diffuse 
across respiratory surface. 
3. Thin plasma membrane 
 rapid diffusion of gases
Unicellular Organism 
No need for specialized respiratory 
structure
• Concentration of O2 is higher in 
surrounding water compared to the cell, 
so O2 diffuse into the cell through 
plasma membrane by simple diffusion 
EXAM TIPS!!! 
• Concentration of CO2 is higher in the cell 
compared to the surrounding water, so 
CO2 diffuse out of the cell through 
plasma membrane by simple diffusion
As animals increase in size: 
What happens to their surface area to volume 
ratio? 
Surface area (cm): 
Volume (cm3): 
Surface area/volume:
The larger the size 
of organism, the 
smaller the TSA/V 
ratio
As animals increase in size: 
What happens to the rate of oxygen 
consumption? 
INCREASES 
What must happen to meet the increased 
demand? 
Specialised respiratory surfaces 
must develop
Give TWO reasons for this statement: 
Some types of animals exchange gases without 
specialised respiratory structures. 
1. the size & shape of the body 
 body is extremely small & 
elongated, as in 
microscopic nematode 
worms: short diffusion 
pathway 
 the body may be thin & 
flattened, producing a large 
surface area for diffusion 
(as in flatworms) 
Nematode worm 
Flatworm
2. if energy demands are low: 
 the relatively slow rate of gas 
exchange by diffusion may suffice 
even for a larger, thicker body e.g. a 
jellyfish
CO2 diffuses 
O out 2 diffuses in 
Earthworm 
Section through 
worm’s skin 
0.04mm 
the blood vessels 
absorb the O2 and 
carry it to the body 
diffusion takes place through 
the thin skin of the worm 
16
RESPIRATORY STRUCTURE in INSECTS
Respiratory structure of Insects 
The tracheal system
Body 
wall 
spiracle 
tracheole 
Body cell 
Trachea 
(Reinforced with rings of chitin which 
prevent from collapsing) 
AIR 
The tracheal system of an insect 
consists of spiracle, trachea, air sac and tracheoles
The tracheal system of insects 
consists of tiny branching tubes that 
penetrate the body
Spiracles 
 are pairs of holes found on the: 
 2nd & 3rd thoracic segments 
 first 8 abdominal segments 
Air sacs 
Spiracle 
Tracheae 
 lead into air-filled sacs 
Spiracles: 
Air enters the 
tracheae through 
spiracles 
Spiracles have 
valves which allow 
air, to go in and out 
of the body 
Air sacs: 
in some larger 
insects contain air 
that speeds up 
movement of gases 
during vigorous 
body movement.
The tracheal system of insects 
provides direct exchange between the 
air and body cells 
Body 
cell 
Tracheole Air 
sac 
Trachea 
Air Body wall
What are ‘tracheae’? 
 branched tubes that lead from 
spiracles 
 reinforced with rings of chitin 
which prevent them from collapsing 
Why is it important to support the 
tracheae? 
If trachea collapses, surface 
area is greatly reduced
Tracheoles: 
Numerous 
 Tiny, end within cells 
 Contains fluid at tip 
 Thin - 1 cell thick 
Why do tracheoles lack a 
chitin lining? 
So that the respiratory 
surface is very thin 
making the diffusion of 
oxygen into the cells 
easy
ADAPTATIONS OF TRACHEOLES 
• Large number- provide large surface area for 
gases exchange 
• Tip of tracheoles have thin permeable wall – 
allow rapid diffusion of respiratory gases 
• Tips of tracheoles have fluid - allow respiratory 
gases to dissolve 
• Direct contact with tissues and organs, O2 
directly diffuse into the cells, and CO2 directly 
diffuse out of the cells (no need blood to 
transport)
Air enters the spiracle then flows into the: 
Tracheae Tracheoles Cells
A closer look at a spiracle of a pupa
Valves & hairs at a spiracle: 
reduce water loss 
Valve open Valve closed
Ventilation (Breathing) movements 
 ventilation is the active movement of air or water 
over an animal's respiratory surface 
 one-way flow of air through the animal occurs 
Air enters in: 
through the thorax 
Air emerges from 
the abdomen 
Circulatory system not involved in transporting O2 and CO2
VENTILATION IN GRASSHOPPER
Breathing Mechanism 
Expiration: 
 Abdominal muscles contract 
& flatten the body 
 volume of the tracheal system decrease 
 air pressure inside trachea increased 
 air is forced out through spiracles 
Inspiration: 
 Abdominal muscles relax & body 
returns to original shape 
 Spiracles open 
 air pressure inside tracheae 
lowered, air drawn in.
Compare Ventilation in mammals: 
Expiration: 
 muscles contract 
Inspiration: 
 is achieved 
passively 
Expiration: 
 muscles relax 
 is achieved passively 
Inspiration: 
 muscles contract
In insects: the circulatory system is not 
involved in respiration 
blood is colourless (no respiratory 
pigment)
Question: [Pg. 139] 
1) Insects use a tracheal system for gas 
exchange, as shown below. 
R 
a) On the diagram use a line labelled R to 
show the respiratory surface. (1)
b) State two advantages of using a 
tracheal system for gas exchange. (2) 
1. Oxygen is transported directly to cells 
2. Provides a large surface area for 
gaseous exchange
Question: [pg. 140] 
3) Gas exchange in insects involves pores 
in the cuticle which open into a network 
of tubes. These tubes have fine branches 
extending into all the tissues of the body. 
a) Name the following: 
The pores in the cuticle. (1) 
Spiracles 
The network of tubes. (1) 
Tracheal system
b) In larger insects, such as locusts, the 
passage of air through the tubes is helped 
by pumping movements of the abdomen. A 
student carried out an experiment to 
investigate the effect of carbon dioxide on 
the rate of these pumping movements. She 
set up the apparatus as shown in the 
diagram below:
The locust was left in the boiling tube for five 
minutes. The number of abdominal pumping 
movements during one minute was counted. The 
student then breathed out once through the 
straw into the boiling tube and immediately 
counted the number of abdominal movements 
during one minute. She repeated this procedure 
varying the number of times she breathed out 
into the boiling tube. The results are shown in 
the table below.
Number of times 
student breathed 
into boiling tube 
Number of abdominal 
pumping movements in 
one minute 
0 16 
1 59 
2 61 
3 58 
4 60 
i) State why the student left the locust in 
the boiling tube for five minutes before 
she began the first count. (1) 
For insect to acclimatise & reach a steady 
rate of breathing.
Number of times student 
breathed into boiling tube 
Number of abdominal pumping 
movements in one minute 
0 16 
1 59 
2 61 
3 58 
4 60 
ii) Describe and comment on the effect of breathing 
out into the boiling tube on the rate of abdominal 
pumping in the locust. (4) 
A slight increase in CO2 concentration. Resulted in a 
high rise in breathing rate. 
Addition of more CO2 did not result in a further 
increase. Brain is sensitive to slight rise in CO2 .
c) (i) During this experiment, the humidity 
of the air in the boiling tube may vary. 
Suggest how this experiment could be 
modified to control the humidity. (2) 
Adding silica gel. 
+ water = pink
(ii) Suggest two factors, other than a 
change in carbon dioxide 
concentration and humidity, which 
may have affected the rate of 
abdominal pumping. (2) 
An increase in temperature. 
Animal becomes stressed.
RESPIRATORY STRUCTURE & BREATHING 
MECHANISM OF AMPHIBIANS
The respiratory structure in an amphibian 
Skin 
Lung
Adaptation of the skin for gases exchange 
1.The skin is 
thin and 
highly 
permeable 
- To allow rapid 
diffusion of 
respiratory 
gases into 
the blood 
capillaries 
2. Beneath the 
skin is a 
network of 
blood 
capillaries 
- To transport 
respiratory 
gases to and 
from body 
cells 
3. The skin is 
kept moist by 
the secretion 
of mucus by 
glands found on 
the outer 
surface of the 
body 
- Facilitate rapid 
and efficient 
exchange of 
gases between 
the skin and 
the environment
Beneath the skin 
is a network of blood capillaries 
– to receive O2 and transport it to body cells
Adaptation of the Lung for gases exchange 
1.The surface 
area for 
gases 
exchange is 
increased by 
numerous 
inner 
partition 
- To increase 
the surface 
area for 
gases 
exchange 
2. Covered 
with a rich 
network of 
blood 
capillary 
- To transport 
respiratory 
gases to and 
from body 
cells 
3. The 
membrane of 
the lungs thin 
and moist 
- Facilitate the 
efficient 
diffusion of 
respiratory 
gases in and 
out rapidly
Floor of the 
mouth lower 
 During inspiration, the nostrils open, the mouth closes, the glottis closes and the 
floor of the mouth cavity is lowered. 
 This decrease the air pressure inside the mouth cavity. As the result, air is 
drawn thorough the nostrils into the mouth cavity. 
 The nostrils close and the floor of the mouth cavity is raised to force the air 
through the glottis into the lungs. The lungs expand and gaseous exchange 
takes place. 
 During expiration, the nostrils open. The muscles of the body wall contracts to 
force the air from the lungs to the mouth cavity and nostrils.
RESPIRATORY STRUCTURE & BREATHING 
MECHANISM OF FISH
Respiratory Structure of Fish 
The Gill
Gill Structure
Operculum is a: 
 movable gill cover that encloses and 
protects the gills
Operculum
Operculum controls: 
 movement of water in and out of the 
opercular cavity like a valve
Gill: 
gill arch + gill filaments 
Gill arch 
Gill filaments
Usually 4 gill arches on either side of the 
fish: 
 support the gills
Gill filaments are thin 
Gill filament 
Gill raker 
[for filter feeding] 
Upper limb 
Lower limb
Each gill is made up of 2 rows of: 
gill filaments 
(primary 
lamellae) 
arranged in the 
shape of a V 
About 70 pairs 
of gill filaments
The upper & lower flat surfaces of each gill 
filament has rows of: 
evenly spaced folds 
or gill plates 
(secondary lamellae)
The gill plates (secondary lamellae): 
increase the 
surface area of the 
respiratory surface 
have a rich supply 
of blood capillaries
What makes fish gills look red? 
A rich blood supply.
The gill plates (secondary lamellae): 
are the exchange surfaces 
Primary lamellae 
or filaments 
Plate-like 
secondary 
lamellae
The gill plates (secondary lamellae): 
are two-cell thick 
Water 
Blood flow 
flow 
Longitudinal section of 
secondary lamella 
Primary lamellae or 
filaments 
Plate-like secondary 
lamellae
Gills are useless out of the water. WHY? 
Gill filaments stick together and surface 
area is reduced
Two types of flow: 
Countercurrent flow: 
 blood in the gill plates 
flows in the opposite 
direction to the water (in 
bony fish) 
Parallel flow [concurrent]: 
 when the two fluids 
travel in the same 
direction (in 
cartilaginous fish)
Countercurrent Mechanism
Explain how a countercurrent flow increases 
the efficiency of gaseous exchange.
Countercurrent Flow is more efficient: 
equlibrium is reached 
blood always comes in contact with water 
having a high O2 concentration
The structural Adaptation of the gills: 
a. Thin filament membrane to allow rapid 
diffusion of respiratory gases into the 
blood capillaries 
b. Rich supply of blood capillaries for efficient 
exchange and transport of respiratory 
gases 
c. Surrounded by water – moist -which 
enable respiratory gases to be dissolved 
d. Large surface area of filaments and 
lamellae for efficient gases exchange
The Mechanism of Countercurrent Exchange 
a. The water flows over the gills in one direction 
b. The blood flows in the opposite direction 
through blood capillaries in the lamellae 
c. As deoxygenated blood enters the blood 
capillaries, it encounters water with a higher 
oxygen content 
d. As the concentration of O2 is higher in water 
than in the blood, O2 diffuses into the blood 
e. And because the concentration of CO2 in the 
blood is higher than in water, CO2 diffuses 
from the blood into the water
Breathing Mechanism in Fish 
EXPIRATION 
INSPIRATION
Inspiration Expiration
• Absorb dissolved oxygen from the 
surrounding water 
• The membrane of the gill filaments is thin – 
allows the absorption of respiratory gases 
INHALATION EXHALATION 
into the blood capillaries 
• The filaments are supplied with blood 
capillaries – for efficient exchange and 
transport of respiratory gases
 During Inhalation, the bony fish 
opens its mouth and lowers the 
floor of the mouth. 
 The pressure inside the mouth 
falls below that of the external 
pressure. This causes water to 
enter the mouth. At the same 
time, it causes the operculum to 
press against the body. 
 Gaseous exchange occurs as 
water flows past the grills. Water 
then passes out through the 
operculum . The operculum 
opens due to increased the 
pressure in the mouth.
RESPIRATORY STRUCTURE AND 
BREATHING MECHANISM OF HUMAN
RESPIRATORY STRUCTURE IN HUMAN 
LUNGS
The Human Respiratory System 
Nasal cavity 
Pharynx 
Larynx (‘voice box’) 
Trachea (‘windpipe’) 
Lungs 
Diaphragm 
- separates chest 
from abdomen
Components of the lower respiratory 
tract
Sequence air passes into human lungs: 
2. Pharynx 
[throat] 1. nasal passages 
4. trachea 3. larynx 
lung 
5. bronchi 
6. bronchioles 
7. alveoli
What happens as air passes through the nasal 
passages? 
Cilia 
Cell membrane 
Mucus
Give TWO functions of mucus in the 
respiratory system.
The wall of the trachea is: 
 held open by 
horizontally C-shaped 
bands of cartilage 
 strengthened
Each lung is surrounded by a pleural cavity 
Pleural cavity: 
contains pleural fluid 
is air-tight 
Pleural fluid: 
lubricates space between two layers
Drainage from pleural cavity
Alveoli
alveolus
The Human Respiratory System 
The wall of each 
alveolus is only one cell 
thick. 
The inner surface is 
coated with a thin film 
of moisture. 
It is supplied by a 
capillary whose 
wall is also only 
one cell thick. 
This is the 
site where 
exchange 
of gases 
takes place!
Alveoli 
form the gas exchange surface
Alveolar wall – 1 cell thick 
consists of very thin, flattened cells: 
reducing the distance over which 
diffusion must occur 
Simple 
Squamous 
Simple 
Cuboidal 
Basement membrane 
Simple 
Columnar
Diameter of capillary is smaller 
than that of a RBC and so: 
RBC move relatively 
slowly 
 more time for 
gaseous exchange 
RBC are squeezed 
 bend into an umbrella shape – expose 
more of their SA to the alveolus: 
 more uptake of O2
Fig. 11 Gaseous exchange inside an alveolus.
1. Gaseous exchange in humans take place in the lungs 
2. Air enters lungs through : 
trachea  bronchi  bronchioles  alveoli 
3. Trachea is supported by cartilage to prevent it from collapse 
during inhalation
Large number of alveoli in the 
lungs 
Walls are made of a single of 
cells 
Walls secrete a thin lining of 
moisture 
Surrounded by a network of 
blood capillaries 
Increased surface area for 
gases exchange 
Gases can diffuse rapidly 
across the thin walls 
Gases can dissolve in moisture 
and diffuse easily across walls 
Can transport oxygen and 
CO2 efficiently 
• l 
ADAPTATION IN ALVEOLUS
The mechanism of 
ventilation (breathing)
A Respiratory Cycle 
 Consists of 
• An inspiration (inhalation) 
• An expiration (exhalation)
Gas Pressure and Volume Relationships
A change in volume causes pressure to 
change
The volume of the thoracic cavity changes by: 
 movements of the: 
 diaphragm  intercostal muscles 
TWO types of intercostal muscles 
between each rib
 slant forwards 
& downwards 
 contract during 
inspiration 
 slant backwards & 
downwards 
 contract during 
expiration
Fig. 12 Position of intercostal muscles. 
The internal intercostal 
muscles contract for the 
ribcage to return back 
The external intercostal 
muscles contract to pull the 
ribcage up and out
Mammals ventilate their lungs by: 
 negative pressure breathing, which pulls air into the 
lungs 
Air inhaled Air exhaled 
Lung 
INHALATION 
Diaphragm contracts 
(moves down) 
EXHALATION 
Diaphragm relaxes 
(moves up) 
Diaphragm 
Rib cage 
expands as 
external 
intercostal 
muscles 
contract 
Rib cage gets 
smaller as 
external 
intercostal 
muscles relax 
Diaphragm is “dome-shaped Diaphragm flattens out.
Inspiration: an active process
Expiration: is largely a passive process
Inspiration Expiration 
Inspiration 
 The external intercostals muscles relax while internal intercostals muscles 
contract, this raising the ribs upwards and outward. 
 At the same time, the diaphragm muscles contract and flatten. 
 Both actions above increase the volume of the rib cage, causing its pressure to 
decreases. 
 Since atmospheric pressure is greater, air is drawn lungs the lungs and they 
inflate.
Mechanism of Breathing 
What happens to your intercostal muscles when you are breathing? 
When you inhale, you… 
Relax your 
Internal intercostal muscles and 
Contract your 
External intercostal muscles 
When you exhale, your… 
External intercostal muscles 
Relax and your 
Internal intercostal muscles 
Contract
Using a Bell Jar to 
demonstrate the 
action of Diaphragm
rubber sheet 
(diaphragm) 
What happens to the balloons when the rubber sheet is 
pulled downwards ? 
The balloons inflate when the rubber sheet is 
pulled downwards. 
Ans: 
glass tube 
(trachea) 
air space of bell 
jar (pleural cavity) 
side tube 
(bronchus) 
wall of bell jar balloon (lung) 
(thoracic wall) 
handle 
balloons are 
inflated as rubber 
sheet is pulled 
downwards 
air
rubber sheet 
(diaphragm) 
What happens when the rubber sheet is released ? 
The balloons return to their original shape when it 
is released. 
Ans: 
glass tube 
(trachea) 
air space of bell jar 
(pleural cavity) 
side tube 
(bronchus) 
wall of bell jar balloon (lung) 
(thoracic wall) 
handle 
balloons are 
inflated as rubber 
sheet is pulled 
downwards 
air
rubber sheet 
(diaphragm) 
When rubber sheet is pulled downwards, volume 
inside bell jar increases and pressure decreases. Air is 
sucked into the balloons and inflated them. . . 
Ans: 
glass tube 
(trachea) 
air space of bell jar 
(pleural cavity) 
side tube 
(bronchus) 
wall of bell jar balloon (lung) 
(thoracic wall) 
handle 
balloons are 
inflated as rubber 
sheet is pulled 
downwards 
air 
Explain how it works.
Explain how it works. 
rubber sheet 
(diaphragm) 
When rubber sheet is released, it becomes flattened. 
Volume inside bell jar decreases but pressure increases. 
Balloons return to original size and force air out. 
Ans: 
glass tube 
(trachea) 
air space of bell jar 
(pleural cavity) 
side tube 
(bronchus) 
wall of bell jar balloon (lung) 
(thoracic wall) 
handle 
balloons are 
inflated as rubber 
sheet is pulled 
downwards 
air
glass tube 
(trachea) 
air space of bell jar 
(pleural cavity) 
side tube 
(bronchus) 
air 
wall of bell jar balloon (lung) 
(thoracic wall) 
rubber sheet 
(diaphragm) 
handle 
balloons are 
inflated as rubber 
sheet is pulled 
downwards 
Explain why this model does not truly and fully reflect 
the actual conditions in man.
It is because : 
• The rubber sheet is controlled by hand 
– the movement of diaphragm is automatic ( contraction brought 
about by diaphragm muscles ) 
• The rubber sheet is flattened at rest 
– the diaphragm is dome-shaped
• The rubber sheet is pulled downwards to fill the 
balloons with air 
– the diaphragm is flattened during inspiration 
• The wall of the bell-jar is rigid 
– rib cage is movable and relatively elastic 
• The cavity is filled with air 
– the pleural cavity is filled with pleural fluid
Using a Rib Cage Model to 
demonstrate the action of 
Intercostal Muscles
Which parts of the human 
chest are represented by rod 
P, rod Q, rod R and the elastic 
band respectively ? 
Rod P, rod Q, rod R and 
the elastic band 
represent the backbone, 
sternum, ribs and 
intercostal muscles 
respectively. 
Ans: 
A 
rod R at 
position Y 
B 
elastic 
band 
rod Q at position X 
rod Q at 
position Y 
rod R at 
position 
x 
rod P
What movement of the 
human body is demonstrated 
when rods Q and R are raised 
from position X to position Y ? 
Upward movement of 
the chest is 
demonstrated when 
rods Q and R are raised 
from position X to 
position Y. 
Ans: 
A 
rod R at 
position Y 
B 
elastic 
band 
rod Q at position X 
rod Q at 
position Y 
rod R at 
position 
x 
rod P
How is the movement in 
Question 2 brought about 
in the human body ? 
It is brought about by 
the contraction of 
intercostal muscles. 
Ans: 
A 
rod R at 
position Y 
B 
elastic 
band 
rod Q at position X 
rod Q at 
position Y 
rod R at 
position 
x 
rod P
What process occurs in the 
human body as a result of 
the movement referred to in 
Question 2 ? 
Ans: Inspiration. 
A 
rod R at 
position Y 
B 
elastic 
band 
rod Q at position X 
rod Q at 
position Y 
rod R at 
position 
x 
rod P
Describe and explain the 
sequence of events 
involved in this process 
referred in Question 2. 
During inspiration the 
volume of the thorax is 
increased and the 
pressure is then 
reduced. Air is forced 
into the lungs. 
Ans: 
A 
rod R at 
position Y 
B 
elastic 
band 
rod Q at position X 
rod Q at 
position Y 
rod R at 
position 
x 
rod P
BREATHING MECHANISMS IN 
HUMAN 
INHALATION EXHALATION 
External intercostal muscles 
contract 
External intercostal muscles 
relax 
Internal intercostal muscles relax Internal intercostal muscles 
contract 
Rib cage move upwards and 
outwards 
Rib cage move downwards and 
inwards 
Diaphragm contracts and flattens Diaphragm relaxes and returns to 
dome-shaped 
Volume of thoracic cavity increase 
resulting in reduced air pressure in 
alveoli 
Volume of thoracic cavity decrease 
resulting in higher air pressure in 
alveoli 
Higher atmospheric pressure 
outside causes air to rush in 
Air is forced out of lungs
Structures Inhalation Exhalation 
External intercostal 
muscles 
Internal intercostal 
muscles 
Rib cage 
Diaphragm 
Volume 
Pressure 
Air flow
1. Respiratory structures involve in gaseous 
exchange: 
a) Across plasma membrane 
b) Tracheal system - insects 
c) Gills - fish 
d) Skin 
e) Lungs
Common characteristics of respiratory structures 
• Moist (gaseous dissolving & 
diffusion) 
• Thin (rapid diffusion) 
• Large surface area per 
volume 
• Network of blood 
capillaries beneath the 
respiratory surfaces.
Compare and contrast the human respiratory 
system with that of other organisms
Adaptati 
on 
Organis 
ms 
Large 
surface 
area 
Respiratory 
structure 
Moisture Network of 
blood 
capillaries 
Protozoa Small size Plasma 
membrane 
Dissolved 
gases 
None 
Insects Numerous 
tracheoles 
Tracheoles Tip of 
tracheoles 
None 
Fish Numerous 
filaments 
and 
lamellae 
filaments 
and lamellae 
Dissolved 
gases 
Available 
Amphibians Lungs 
skin 
Lungs and 
skin 
Wet skin Available 
Humans Numerous 
alveoli Moist 
Available
Respirometer is used to find: 
the RATE of 
respiration 
measured as: 
volume of oxygen 
consumed/g/minute
Coloured fluid in manometer
What is the purpose 
of the glass beads in 
tube X? 
Control 
Suggest how a 
temperature of 25C 
could be obtained 
simultaneously in 
tube X and Y. 
Place in a water bath
Respirometer
Respirometer
END OF PART 1

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BIOLOGY FORM 4 CHAPTER 7 - RESPIRATION PART 1

  • 1. BIOLOGY FORM 4 CHAPTER 7 RESPIRATION PART 1
  • 2. Objectives 7.1 Understanding the respiratory processes in energy production 7.2 Analysing the respiratory structure and breathing mechanism in human and animal 7.3 Understanding the concept of gaseous exchange across the respiratory surfaces and transport of gases in human 7.4 Understanding the regulatory mechanism in respiration 7.5 Realising the importance of maintaining a healthy respiratory system 7.6 Understanding respiration in plants
  • 3. 7.1 Understanding the respiratory processes in energy production
  • 5. cells need to: obtain O2 WHY? eliminate CO2 WHY?
  • 6. cells need to: obtain O2 to produce ATP eliminate CO2 to prevent toxic effects
  • 7. What is respiration?? Process of obtaining oxygen and delivering it to the cells for cellular respiration and removing carbon dioxide produced by cells
  • 8. Respiration External Respiration (Breathing) Internal Respiration (Cellular respiration) Aerobic Respiration Anaerobic Respiration 2 stages 2 types
  • 9. External respiration (Breathing) • The exchange of respiratory gases (oxygen and carbon dioxide) between the body and the environment
  • 10. Internal respiration ( Cellular Respiration) • A metabolic process • which occurs in cells, • involves oxidation of organic molecules(food) • to produce energy (in the form of ATP) • Controlled by enzymes Two types : 1. Aerobic respiration 2. Anaerobic respiration
  • 11.
  • 12. The main substrate to produce energy is GLUCOSE
  • 13. Fuels are used in sequence Muscle Glucose is stored here as glycogen and is used when the body is working harder. 1. CARBOHYDRATES 2. FATS 3. PROTEINS Liver Here some of the glucose is stored as glycogen and used to maintain blood sugar levels. Used when the carbohydrates are exhausted. Are first converted to glycerol and fatty acids Used when carbohydrates and fats have been used up as during prolonged starvation
  • 14.
  • 16. How does body convert energy stored in food  energy for body use?
  • 17. Through Cellular Respiration  Cellular Respiration is the oxidation of food (glucose) with the release of energy in living cells 2 Types of Cellular Respiration: Aerobic and Anaerobic respiration
  • 18. Aerobic respiration • Require oxygen • Glucose is completely oxidised • to produce 36 - 38 molecules of ATP / 2898 kJ energy (high energy) • Takes place in the cytoplasm and mitochondria C6H12O6 + 6O2 6CO2 + 6H2O + Energy (2898 kJ)
  • 19. Anaerobic respiration • Without oxygen • Glucose is not completely broken down • Releases only 2 ATP (low energy) • Takes place in the cytoplasm • Eg. In human muscles, yeast, microbes in mud Yeast: Glucose  Carbon dioxide + ethanol + 210 kJ energy Muscle: Glucose  Lactic acid + 150 kJ energy
  • 20. Some microbes living in the mud… low oxygen level … Respire ananerobically!
  • 23. Anaerobic respiration in yeast •Yeast normally respires aerobically •Anaerobic respiration in yeast produces ethanol, carbon dioxide and energy
  • 24. IN YEAST • Anaerobic respiration in yeast also known as fermentation C6H12O6 2CO2 + 2C2H5OH + Energy(210kJ) ethanol Zymase • Ethanol can be used in wine & beer production • CO2 released causes the dough to rise (to make bread)
  • 25. Alcoholic Fermentation C6H12O6  2C2H5OH + 2CO2 + energy glucose ethanol carbon dioxide • Occurs in yeast cells.
  • 26. Dough rising 36 The yeast is mixed with the dough After 1 hour in a warm place the dough has risen as a result of the carbon dioxide produced by the yeast
  • 27. Anaerobic Respiration Glucose (with baker’s yeast)  Carbon dioxide + ethanol + little energy (210kJ) The ‘holes’ in the bread are made by the carbon dioxide bubbles. This gives the bread a ‘light’ texture
  • 28. Anaerobic respiration in humans! Highly intensive exercise Glucose  Lactic acid + energy
  • 29. Anaerobic Respiration in the Muscles 1. Vigorous muscle movement  increase rate of aerobic respiration to release more energy. Glucose + oxygen  Carbon dioxide + water + 2898kJ energy
  • 30. What happens when you need more energy but there’s not enough oxygen?
  • 31. Muscle cells (anaerobic respiration) • Prolonged physical activity - O2 supplied not enough - O2 needed > O2 supplied - muscle cells undergo anaerobic respiration • Muscles in state of O2 deficiency  O2 debt occurred • Oxygen debt : muscle cells produce ATP without oxygen
  • 32. • Glucose molecules break down partially into Lactic Acid C6H12O6 2C3H6O3 + Energy (150kJ) lactic acid • Energy low because much of energy still trapped within molecules of lactic acid. • High concentration of lactic acid may cause muscular cramp and fatigue, tiredness
  • 33. “Repaying” oxygen debt • After the activity the person need to breathe deeply and rapidly to inhale more O2 - O2 is used to oxidise accumulated lactic acid to form CO2 and H2O (occur mainly in liver) Lactic acid + O2 CO2 + H2O + energy Remaining lactic acid converted into glycogen and stored in muscle cells
  • 34. Oxygen Debt Question: How do sprinters pay back their oxygen debt at the end of a race? Answer: Sprinters will continue to breathe more deeply and rapidly for a number of minutes at the end of their race. This will enable them to pay back the oxygen debt, and allow lactic acid levels to fall.
  • 35. Oxygen debt The amount of oxygen needed to remove lactic acid from muscle cells is called oxygen debt The time taken to remove all the lactic acid is called the recovery period
  • 36. • Oxygen debt is paid off when all of lactic acid is removed (increasing breathing rate after vigorous activity)
  • 37. Energy needed for vigorous exercise Glucose + oxygen  Carbon dioxide + water + 2898 kJ Glucose + Oxygen  Lactic acid + 150 kJ Total amount of energy needed for vigorous muscular contractions Aerobic respiration Anaerobic respiration
  • 38. Why aerobic respiration produced more energy than anaerobic respiration???
  • 39. Why are virtually all organisms aerobes? More ATP released in aerobic rather than in anaerobic respiration
  • 40. Aerobic and Anaerobic Respiration RESPIRATION Anaerobic Respiration Alcoholic Fermentation Lactic Acid Production Aerobic Respiration C6H12O6 + 6O2  6CO2 + 6H2O + energy glucose oxygen carbon water dioxide C6H12O6  2C2H5OH + 2CO2 + energy glucose ethanol carbon dioxide • Occurs in yeast cells. C6H12O6  2C3H6O3 + energy glucose lactic acid • Occurs in muscle cells. • Leads to fatigue.
  • 41.  SIMILARITIES  Cellular respiration  Involve the breakdown of glucose  Produces energy  Are catalyzed by enzymes  Occurs in animal and plants
  • 42. Differences between Aerobic Respiration & Anaerobic Respiration Aerobic Respiration Items Anaerobic Respiration Almost every living cells Work in Certain plant, yeast, bacteria and muscle Required Oxygen requirement Not required Complete oxidation Oxidation of glucose Incomplete oxidation CO2, Water and Energy Product Yeast CO2, Ethanol and Energy Muscle Lactic acid and Energy
  • 43. Differences between Aerobic Respiration & Anaerobic Respiration Aerobic Respiration Items Anaerobic Respiration Large amount Energy released Small amount Mitochondria and Site Cytoplasm cytoplasm C6H12O6 + 6O2 Glucose ↓ 6CO2 + H20 + 2898 kJ Energy Chemical Equation In Yeast: C6H12O6 Glucose ↓ 2CO2 + 2C2H5OH + 210 kJ Ethanol Energy In Muscle cells: C6H12O6 Glucose ↓ 2C3H6O3 + 150kJ Lactic acid Energy 38 molecules Number of ATP molecules produced 2 molecules
  • 44. • This apparatus can be used to investigate how small living organisms respire such as woodlice, maggots or germinating seeds. Living organisms Gauze Hydrogen carbonate indicator – This will change colour from red to yellow when the carbon dioxide level increases due to respiration.
  • 45. The germinating seeds are respiring and therefore releasing heat. The boiled seeds have been killed and are therefore not respiring anymore. Cotton wool Thermometer Thermal flask
  • 46. 7.2 Analysing the respiratory structure and breathing mechanism in human and animal
  • 47.  LEARNING OUTCOMES:  State the respiratory structures in humans and some animals  Describe the characteristics of respiratory surfaces in humans and other organisms  Describe breathing mechanisms in human and other organisms  Compare and contrast the human respiratory system with other organisms
  • 48. Gaseous exchange: is the exchange of oxygen and carbon dioxide between the environment and the organism takes place in all organisms by diffusion
  • 49. A ‘respiratory surface’ is the: area where gaseous exchange actually takes place
  • 50. Adaptations of respiratory structures (General characteristics) 1. Moist – easy for gases to dissolve before diffuse 2. Thin – allow rapid diffusion of gases 3. Large surface area – efficient gaseous exchange 4. Covered by a network of blood capillaries – efficient exchange and transport of respiratory gases
  • 51. Organisms acquire their oxygen: direct from the atmosphere dissolved in water 1 2
  • 52. oxygen Unicellular organisms carbon dioxide maximum distance is 0.1 mm The distance is so small that diffusion is rapid enough for the cell’s needs Amoeba
  • 53. Protozoa – Unicellular Organism Oxygen nutrients Carbon dioxide Waste products The respiratory surface of an unicellular organism is through plasma membrane
  • 54. Adaptations 1. Small Size  large surface area to volume (TSA/V) ratio  rate of diffusion increases 2. Wet surroundings  plasma membrane constantly moist  gases easily dissolve and diffuse across respiratory surface. 3. Thin plasma membrane  rapid diffusion of gases
  • 55. Unicellular Organism No need for specialized respiratory structure
  • 56. • Concentration of O2 is higher in surrounding water compared to the cell, so O2 diffuse into the cell through plasma membrane by simple diffusion EXAM TIPS!!! • Concentration of CO2 is higher in the cell compared to the surrounding water, so CO2 diffuse out of the cell through plasma membrane by simple diffusion
  • 57. As animals increase in size: What happens to their surface area to volume ratio? Surface area (cm): Volume (cm3): Surface area/volume:
  • 58. The larger the size of organism, the smaller the TSA/V ratio
  • 59. As animals increase in size: What happens to the rate of oxygen consumption? INCREASES What must happen to meet the increased demand? Specialised respiratory surfaces must develop
  • 60. Give TWO reasons for this statement: Some types of animals exchange gases without specialised respiratory structures. 1. the size & shape of the body  body is extremely small & elongated, as in microscopic nematode worms: short diffusion pathway  the body may be thin & flattened, producing a large surface area for diffusion (as in flatworms) Nematode worm Flatworm
  • 61. 2. if energy demands are low:  the relatively slow rate of gas exchange by diffusion may suffice even for a larger, thicker body e.g. a jellyfish
  • 62. CO2 diffuses O out 2 diffuses in Earthworm Section through worm’s skin 0.04mm the blood vessels absorb the O2 and carry it to the body diffusion takes place through the thin skin of the worm 16
  • 64. Respiratory structure of Insects The tracheal system
  • 65. Body wall spiracle tracheole Body cell Trachea (Reinforced with rings of chitin which prevent from collapsing) AIR The tracheal system of an insect consists of spiracle, trachea, air sac and tracheoles
  • 66. The tracheal system of insects consists of tiny branching tubes that penetrate the body
  • 67. Spiracles  are pairs of holes found on the:  2nd & 3rd thoracic segments  first 8 abdominal segments Air sacs Spiracle Tracheae  lead into air-filled sacs Spiracles: Air enters the tracheae through spiracles Spiracles have valves which allow air, to go in and out of the body Air sacs: in some larger insects contain air that speeds up movement of gases during vigorous body movement.
  • 68. The tracheal system of insects provides direct exchange between the air and body cells Body cell Tracheole Air sac Trachea Air Body wall
  • 69. What are ‘tracheae’?  branched tubes that lead from spiracles  reinforced with rings of chitin which prevent them from collapsing Why is it important to support the tracheae? If trachea collapses, surface area is greatly reduced
  • 70. Tracheoles: Numerous  Tiny, end within cells  Contains fluid at tip  Thin - 1 cell thick Why do tracheoles lack a chitin lining? So that the respiratory surface is very thin making the diffusion of oxygen into the cells easy
  • 71. ADAPTATIONS OF TRACHEOLES • Large number- provide large surface area for gases exchange • Tip of tracheoles have thin permeable wall – allow rapid diffusion of respiratory gases • Tips of tracheoles have fluid - allow respiratory gases to dissolve • Direct contact with tissues and organs, O2 directly diffuse into the cells, and CO2 directly diffuse out of the cells (no need blood to transport)
  • 72. Air enters the spiracle then flows into the: Tracheae Tracheoles Cells
  • 73. A closer look at a spiracle of a pupa
  • 74. Valves & hairs at a spiracle: reduce water loss Valve open Valve closed
  • 75. Ventilation (Breathing) movements  ventilation is the active movement of air or water over an animal's respiratory surface  one-way flow of air through the animal occurs Air enters in: through the thorax Air emerges from the abdomen Circulatory system not involved in transporting O2 and CO2
  • 77. Breathing Mechanism Expiration:  Abdominal muscles contract & flatten the body  volume of the tracheal system decrease  air pressure inside trachea increased  air is forced out through spiracles Inspiration:  Abdominal muscles relax & body returns to original shape  Spiracles open  air pressure inside tracheae lowered, air drawn in.
  • 78. Compare Ventilation in mammals: Expiration:  muscles contract Inspiration:  is achieved passively Expiration:  muscles relax  is achieved passively Inspiration:  muscles contract
  • 79. In insects: the circulatory system is not involved in respiration blood is colourless (no respiratory pigment)
  • 80. Question: [Pg. 139] 1) Insects use a tracheal system for gas exchange, as shown below. R a) On the diagram use a line labelled R to show the respiratory surface. (1)
  • 81. b) State two advantages of using a tracheal system for gas exchange. (2) 1. Oxygen is transported directly to cells 2. Provides a large surface area for gaseous exchange
  • 82. Question: [pg. 140] 3) Gas exchange in insects involves pores in the cuticle which open into a network of tubes. These tubes have fine branches extending into all the tissues of the body. a) Name the following: The pores in the cuticle. (1) Spiracles The network of tubes. (1) Tracheal system
  • 83. b) In larger insects, such as locusts, the passage of air through the tubes is helped by pumping movements of the abdomen. A student carried out an experiment to investigate the effect of carbon dioxide on the rate of these pumping movements. She set up the apparatus as shown in the diagram below:
  • 84. The locust was left in the boiling tube for five minutes. The number of abdominal pumping movements during one minute was counted. The student then breathed out once through the straw into the boiling tube and immediately counted the number of abdominal movements during one minute. She repeated this procedure varying the number of times she breathed out into the boiling tube. The results are shown in the table below.
  • 85. Number of times student breathed into boiling tube Number of abdominal pumping movements in one minute 0 16 1 59 2 61 3 58 4 60 i) State why the student left the locust in the boiling tube for five minutes before she began the first count. (1) For insect to acclimatise & reach a steady rate of breathing.
  • 86. Number of times student breathed into boiling tube Number of abdominal pumping movements in one minute 0 16 1 59 2 61 3 58 4 60 ii) Describe and comment on the effect of breathing out into the boiling tube on the rate of abdominal pumping in the locust. (4) A slight increase in CO2 concentration. Resulted in a high rise in breathing rate. Addition of more CO2 did not result in a further increase. Brain is sensitive to slight rise in CO2 .
  • 87. c) (i) During this experiment, the humidity of the air in the boiling tube may vary. Suggest how this experiment could be modified to control the humidity. (2) Adding silica gel. + water = pink
  • 88. (ii) Suggest two factors, other than a change in carbon dioxide concentration and humidity, which may have affected the rate of abdominal pumping. (2) An increase in temperature. Animal becomes stressed.
  • 89. RESPIRATORY STRUCTURE & BREATHING MECHANISM OF AMPHIBIANS
  • 90. The respiratory structure in an amphibian Skin Lung
  • 91. Adaptation of the skin for gases exchange 1.The skin is thin and highly permeable - To allow rapid diffusion of respiratory gases into the blood capillaries 2. Beneath the skin is a network of blood capillaries - To transport respiratory gases to and from body cells 3. The skin is kept moist by the secretion of mucus by glands found on the outer surface of the body - Facilitate rapid and efficient exchange of gases between the skin and the environment
  • 92. Beneath the skin is a network of blood capillaries – to receive O2 and transport it to body cells
  • 93. Adaptation of the Lung for gases exchange 1.The surface area for gases exchange is increased by numerous inner partition - To increase the surface area for gases exchange 2. Covered with a rich network of blood capillary - To transport respiratory gases to and from body cells 3. The membrane of the lungs thin and moist - Facilitate the efficient diffusion of respiratory gases in and out rapidly
  • 94. Floor of the mouth lower  During inspiration, the nostrils open, the mouth closes, the glottis closes and the floor of the mouth cavity is lowered.  This decrease the air pressure inside the mouth cavity. As the result, air is drawn thorough the nostrils into the mouth cavity.  The nostrils close and the floor of the mouth cavity is raised to force the air through the glottis into the lungs. The lungs expand and gaseous exchange takes place.  During expiration, the nostrils open. The muscles of the body wall contracts to force the air from the lungs to the mouth cavity and nostrils.
  • 95. RESPIRATORY STRUCTURE & BREATHING MECHANISM OF FISH
  • 96. Respiratory Structure of Fish The Gill
  • 98. Operculum is a:  movable gill cover that encloses and protects the gills
  • 100. Operculum controls:  movement of water in and out of the opercular cavity like a valve
  • 101. Gill: gill arch + gill filaments Gill arch Gill filaments
  • 102. Usually 4 gill arches on either side of the fish:  support the gills
  • 103.
  • 104. Gill filaments are thin Gill filament Gill raker [for filter feeding] Upper limb Lower limb
  • 105. Each gill is made up of 2 rows of: gill filaments (primary lamellae) arranged in the shape of a V About 70 pairs of gill filaments
  • 106. The upper & lower flat surfaces of each gill filament has rows of: evenly spaced folds or gill plates (secondary lamellae)
  • 107. The gill plates (secondary lamellae): increase the surface area of the respiratory surface have a rich supply of blood capillaries
  • 108. What makes fish gills look red? A rich blood supply.
  • 109. The gill plates (secondary lamellae): are the exchange surfaces Primary lamellae or filaments Plate-like secondary lamellae
  • 110. The gill plates (secondary lamellae): are two-cell thick Water Blood flow flow Longitudinal section of secondary lamella Primary lamellae or filaments Plate-like secondary lamellae
  • 111. Gills are useless out of the water. WHY? Gill filaments stick together and surface area is reduced
  • 112. Two types of flow: Countercurrent flow:  blood in the gill plates flows in the opposite direction to the water (in bony fish) Parallel flow [concurrent]:  when the two fluids travel in the same direction (in cartilaginous fish)
  • 114. Explain how a countercurrent flow increases the efficiency of gaseous exchange.
  • 115. Countercurrent Flow is more efficient: equlibrium is reached blood always comes in contact with water having a high O2 concentration
  • 116. The structural Adaptation of the gills: a. Thin filament membrane to allow rapid diffusion of respiratory gases into the blood capillaries b. Rich supply of blood capillaries for efficient exchange and transport of respiratory gases c. Surrounded by water – moist -which enable respiratory gases to be dissolved d. Large surface area of filaments and lamellae for efficient gases exchange
  • 117. The Mechanism of Countercurrent Exchange a. The water flows over the gills in one direction b. The blood flows in the opposite direction through blood capillaries in the lamellae c. As deoxygenated blood enters the blood capillaries, it encounters water with a higher oxygen content d. As the concentration of O2 is higher in water than in the blood, O2 diffuses into the blood e. And because the concentration of CO2 in the blood is higher than in water, CO2 diffuses from the blood into the water
  • 118. Breathing Mechanism in Fish EXPIRATION INSPIRATION
  • 120. • Absorb dissolved oxygen from the surrounding water • The membrane of the gill filaments is thin – allows the absorption of respiratory gases INHALATION EXHALATION into the blood capillaries • The filaments are supplied with blood capillaries – for efficient exchange and transport of respiratory gases
  • 121.  During Inhalation, the bony fish opens its mouth and lowers the floor of the mouth.  The pressure inside the mouth falls below that of the external pressure. This causes water to enter the mouth. At the same time, it causes the operculum to press against the body.  Gaseous exchange occurs as water flows past the grills. Water then passes out through the operculum . The operculum opens due to increased the pressure in the mouth.
  • 122. RESPIRATORY STRUCTURE AND BREATHING MECHANISM OF HUMAN
  • 123. RESPIRATORY STRUCTURE IN HUMAN LUNGS
  • 124. The Human Respiratory System Nasal cavity Pharynx Larynx (‘voice box’) Trachea (‘windpipe’) Lungs Diaphragm - separates chest from abdomen
  • 125. Components of the lower respiratory tract
  • 126. Sequence air passes into human lungs: 2. Pharynx [throat] 1. nasal passages 4. trachea 3. larynx lung 5. bronchi 6. bronchioles 7. alveoli
  • 127. What happens as air passes through the nasal passages? Cilia Cell membrane Mucus
  • 128. Give TWO functions of mucus in the respiratory system.
  • 129. The wall of the trachea is:  held open by horizontally C-shaped bands of cartilage  strengthened
  • 130.
  • 131. Each lung is surrounded by a pleural cavity Pleural cavity: contains pleural fluid is air-tight Pleural fluid: lubricates space between two layers
  • 135. The Human Respiratory System The wall of each alveolus is only one cell thick. The inner surface is coated with a thin film of moisture. It is supplied by a capillary whose wall is also only one cell thick. This is the site where exchange of gases takes place!
  • 136. Alveoli form the gas exchange surface
  • 137. Alveolar wall – 1 cell thick consists of very thin, flattened cells: reducing the distance over which diffusion must occur Simple Squamous Simple Cuboidal Basement membrane Simple Columnar
  • 138.
  • 139. Diameter of capillary is smaller than that of a RBC and so: RBC move relatively slowly  more time for gaseous exchange RBC are squeezed  bend into an umbrella shape – expose more of their SA to the alveolus:  more uptake of O2
  • 140. Fig. 11 Gaseous exchange inside an alveolus.
  • 141. 1. Gaseous exchange in humans take place in the lungs 2. Air enters lungs through : trachea  bronchi  bronchioles  alveoli 3. Trachea is supported by cartilage to prevent it from collapse during inhalation
  • 142. Large number of alveoli in the lungs Walls are made of a single of cells Walls secrete a thin lining of moisture Surrounded by a network of blood capillaries Increased surface area for gases exchange Gases can diffuse rapidly across the thin walls Gases can dissolve in moisture and diffuse easily across walls Can transport oxygen and CO2 efficiently • l ADAPTATION IN ALVEOLUS
  • 143. The mechanism of ventilation (breathing)
  • 144. A Respiratory Cycle  Consists of • An inspiration (inhalation) • An expiration (exhalation)
  • 145. Gas Pressure and Volume Relationships
  • 146. A change in volume causes pressure to change
  • 147.
  • 148. The volume of the thoracic cavity changes by:  movements of the:  diaphragm  intercostal muscles TWO types of intercostal muscles between each rib
  • 149.  slant forwards & downwards  contract during inspiration  slant backwards & downwards  contract during expiration
  • 150. Fig. 12 Position of intercostal muscles. The internal intercostal muscles contract for the ribcage to return back The external intercostal muscles contract to pull the ribcage up and out
  • 151. Mammals ventilate their lungs by:  negative pressure breathing, which pulls air into the lungs Air inhaled Air exhaled Lung INHALATION Diaphragm contracts (moves down) EXHALATION Diaphragm relaxes (moves up) Diaphragm Rib cage expands as external intercostal muscles contract Rib cage gets smaller as external intercostal muscles relax Diaphragm is “dome-shaped Diaphragm flattens out.
  • 153. Expiration: is largely a passive process
  • 154. Inspiration Expiration Inspiration  The external intercostals muscles relax while internal intercostals muscles contract, this raising the ribs upwards and outward.  At the same time, the diaphragm muscles contract and flatten.  Both actions above increase the volume of the rib cage, causing its pressure to decreases.  Since atmospheric pressure is greater, air is drawn lungs the lungs and they inflate.
  • 155. Mechanism of Breathing What happens to your intercostal muscles when you are breathing? When you inhale, you… Relax your Internal intercostal muscles and Contract your External intercostal muscles When you exhale, your… External intercostal muscles Relax and your Internal intercostal muscles Contract
  • 156.
  • 157. Using a Bell Jar to demonstrate the action of Diaphragm
  • 158. rubber sheet (diaphragm) What happens to the balloons when the rubber sheet is pulled downwards ? The balloons inflate when the rubber sheet is pulled downwards. Ans: glass tube (trachea) air space of bell jar (pleural cavity) side tube (bronchus) wall of bell jar balloon (lung) (thoracic wall) handle balloons are inflated as rubber sheet is pulled downwards air
  • 159. rubber sheet (diaphragm) What happens when the rubber sheet is released ? The balloons return to their original shape when it is released. Ans: glass tube (trachea) air space of bell jar (pleural cavity) side tube (bronchus) wall of bell jar balloon (lung) (thoracic wall) handle balloons are inflated as rubber sheet is pulled downwards air
  • 160. rubber sheet (diaphragm) When rubber sheet is pulled downwards, volume inside bell jar increases and pressure decreases. Air is sucked into the balloons and inflated them. . . Ans: glass tube (trachea) air space of bell jar (pleural cavity) side tube (bronchus) wall of bell jar balloon (lung) (thoracic wall) handle balloons are inflated as rubber sheet is pulled downwards air Explain how it works.
  • 161. Explain how it works. rubber sheet (diaphragm) When rubber sheet is released, it becomes flattened. Volume inside bell jar decreases but pressure increases. Balloons return to original size and force air out. Ans: glass tube (trachea) air space of bell jar (pleural cavity) side tube (bronchus) wall of bell jar balloon (lung) (thoracic wall) handle balloons are inflated as rubber sheet is pulled downwards air
  • 162. glass tube (trachea) air space of bell jar (pleural cavity) side tube (bronchus) air wall of bell jar balloon (lung) (thoracic wall) rubber sheet (diaphragm) handle balloons are inflated as rubber sheet is pulled downwards Explain why this model does not truly and fully reflect the actual conditions in man.
  • 163. It is because : • The rubber sheet is controlled by hand – the movement of diaphragm is automatic ( contraction brought about by diaphragm muscles ) • The rubber sheet is flattened at rest – the diaphragm is dome-shaped
  • 164. • The rubber sheet is pulled downwards to fill the balloons with air – the diaphragm is flattened during inspiration • The wall of the bell-jar is rigid – rib cage is movable and relatively elastic • The cavity is filled with air – the pleural cavity is filled with pleural fluid
  • 165. Using a Rib Cage Model to demonstrate the action of Intercostal Muscles
  • 166. Which parts of the human chest are represented by rod P, rod Q, rod R and the elastic band respectively ? Rod P, rod Q, rod R and the elastic band represent the backbone, sternum, ribs and intercostal muscles respectively. Ans: A rod R at position Y B elastic band rod Q at position X rod Q at position Y rod R at position x rod P
  • 167. What movement of the human body is demonstrated when rods Q and R are raised from position X to position Y ? Upward movement of the chest is demonstrated when rods Q and R are raised from position X to position Y. Ans: A rod R at position Y B elastic band rod Q at position X rod Q at position Y rod R at position x rod P
  • 168. How is the movement in Question 2 brought about in the human body ? It is brought about by the contraction of intercostal muscles. Ans: A rod R at position Y B elastic band rod Q at position X rod Q at position Y rod R at position x rod P
  • 169. What process occurs in the human body as a result of the movement referred to in Question 2 ? Ans: Inspiration. A rod R at position Y B elastic band rod Q at position X rod Q at position Y rod R at position x rod P
  • 170. Describe and explain the sequence of events involved in this process referred in Question 2. During inspiration the volume of the thorax is increased and the pressure is then reduced. Air is forced into the lungs. Ans: A rod R at position Y B elastic band rod Q at position X rod Q at position Y rod R at position x rod P
  • 171. BREATHING MECHANISMS IN HUMAN INHALATION EXHALATION External intercostal muscles contract External intercostal muscles relax Internal intercostal muscles relax Internal intercostal muscles contract Rib cage move upwards and outwards Rib cage move downwards and inwards Diaphragm contracts and flattens Diaphragm relaxes and returns to dome-shaped Volume of thoracic cavity increase resulting in reduced air pressure in alveoli Volume of thoracic cavity decrease resulting in higher air pressure in alveoli Higher atmospheric pressure outside causes air to rush in Air is forced out of lungs
  • 172. Structures Inhalation Exhalation External intercostal muscles Internal intercostal muscles Rib cage Diaphragm Volume Pressure Air flow
  • 173. 1. Respiratory structures involve in gaseous exchange: a) Across plasma membrane b) Tracheal system - insects c) Gills - fish d) Skin e) Lungs
  • 174. Common characteristics of respiratory structures • Moist (gaseous dissolving & diffusion) • Thin (rapid diffusion) • Large surface area per volume • Network of blood capillaries beneath the respiratory surfaces.
  • 175. Compare and contrast the human respiratory system with that of other organisms
  • 176. Adaptati on Organis ms Large surface area Respiratory structure Moisture Network of blood capillaries Protozoa Small size Plasma membrane Dissolved gases None Insects Numerous tracheoles Tracheoles Tip of tracheoles None Fish Numerous filaments and lamellae filaments and lamellae Dissolved gases Available Amphibians Lungs skin Lungs and skin Wet skin Available Humans Numerous alveoli Moist Available
  • 177. Respirometer is used to find: the RATE of respiration measured as: volume of oxygen consumed/g/minute
  • 178. Coloured fluid in manometer
  • 179. What is the purpose of the glass beads in tube X? Control Suggest how a temperature of 25C could be obtained simultaneously in tube X and Y. Place in a water bath