Journal Club March 2010

A Trial of Darbepoetin Alfa in Type 2 Diabetes and Chronic Kidney Disease NEJM Volume 361:2019-2032 November 19, 2009 Number 21 Wafa Badwan, MD March 16, 2010

Introduction ,[object Object],[object Object],[object Object]

Introduction ,[object Object],[object Object]

Methods ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Study Population ,[object Object],[object Object],[object Object],[object Object]

Study Population ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Study Procedures ,[object Object],[object Object],[object Object],[object Object]

Study Procedures ,[object Object],[object Object]

Evaluation of Outcomes ,[object Object],[object Object]

Monitoring ,[object Object],[object Object],[object Object]

Statistical Analysis ,[object Object],[object Object],[object Object],[object Object],[object Object]

Results ,[object Object],[object Object],[object Object],[object Object]

Results ,[object Object],[object Object],[object Object],[object Object],[object Object]

Figure 1- Mean Hemoglobin levels through 48 months among patients who were assigned to receive Darbepoetin Alfa or placebo

Results ,[object Object],[object Object],[object Object]

Figure 2 Kaplan-Meier Estimates of the Probability of the Primary and Secondary End Points

Figure 3- Kaplan Meier Estimates of the Probability of Renal Outcomes

Results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Results ,[object Object],[object Object]

Summary ,[object Object],[object Object]

Summary ,[object Object],[object Object],[object Object],[object Object]

Journal Club March 2010

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Journal Club March 2010