This is a presentation from the Canadian Bovine Genomics Workshop held in Calgary, Alberta on Sept.14, 2009. The workshop was the first step in developing a national bovine genomics strategy for Canada.

1. ALMA Alberta Livestock & Meat Agency Ltd. Canadian Bovine Genomics Workshop September 14, 2009 Calgary, Alberta

2. Genomics in Beef Today – a vision of genomics from farm to fork Ronan Loftus – IdentiGEN Canadian Bovine Genomics Workshop Calgary – Sept ‘09

4. Single device/operator per year Moore’s Law for genomics: DNA sequencing capacity doubling time ~15 months Source: Prof D MacHugh, UCD 1 bp 10 bp 100 bp 1 kilobase 10 kilobase 100 kilobase 1 megabase 10 megabase 100 megabase 1 gigabase 10 gigabase 1960 1970 1980 1990 2000 2010 100 gigabase 1000 gigabase

5. Modified from The Economist (April 16 th , 2009) DNA sequencing costs and the growth of DNA sequence data 1971 80 90 2000 08 $0.00001 $0.0001 $0.001 $0.01 $0.1 $1 $10 $100 $1,000 $10,000 Sequencing cost per base pair (bp) 10 2 10 3 10 4 10 5 10 6 10 7 10 8 10 9 10 10 10 11 Growth in GenBank DNA sequence data (bp)

7. Genomics: Potential Roles

10. Traceability & Consumer confidence Hen House - US retailer McDonalds - Ireland Tesco/Homeplus - Korea retailer Pedigree – UK Pet food

11. International Trade Europe – traceability mandatory Brazilian export ban due to lack of traceability Batch No Japan – traceability mandatory Key focus of New Administration? Korea – traceability mandatory DNA Sampling for cattle mandatory “ The announcement by South Korea reinforces the message that the U.S. industry needs to move forward with a traceability program if it is serious about remaining competitive in the international marketplace,”

12. Jan ’08 - U.S. Department of Agriculture announced the largest beef recall in its history ~ 150 million Lbs Crisis Management Irish Dioxin Crisis (Dec ’08) Pork – 10 farms involved 3 months pork production recalled $250 million government support Beef – 50 farms involved Minimized recall Industry reputation & damage limited

13. The traceability challenge! Consumer Perception Domestic Retail Foodservice Export

20. www.identigen.com Thank You For further information please contact rloftus@identigen.com