Preterm doğum ve emr

Preterm Doğum ve EMR Dr. Mekin Sezik

Preterm doğum (PTD) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Tanımlar ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PTD niçin önemli? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Azametli (!) Obstetrik Sendromlar (Great Obstetrical Syndromes) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Çoğul Etyoloji ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Enfeksiyon Enflamasyon Uteroplasental iskemi Uterusta anormal gerilme Allerjik / İmünolojik faktörler Servikal hastalık Endokrin bozukluklar PTD

Preterm doğum patogenezinde enfeksiyon I – Servikal yoldan asendan olarak ilerleme II – Koryoamniyotik zar invazyonu III – İntra-amniyotik kolonizasyon (MIAC, microbial invasion of the amniotic cavity) IV – Fötal enflamatuvar cevap sendromu (FIRS, fetal inflammatory response syndrome) Kaynak: Romero et al, 2006

Gonore Chlamydia Ureaplasma Mycoplasma Anaerobik (BV) Il-1 Il-6 TNF vs Pg sentezi Fötal beyin (beyaz cevher) hasarı EMR / PTD Nörolojik hasar

Uterin gerilme ,[object Object],[object Object],[object Object],[object Object]

Servikal faktörler ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Gebelikte servikal değişiklikler Faz I Yumuşama Kolajen çözünürlüğünde artış Doku kompliansında artış II Olgunlaşma Doku kompliansında artış Yapısal bütünlükte bozulma Hyaluronan sentezi, hidrasyon Stromada enflamatuvar hücre artışı III Dilatasyon Uterin kontraksiyonların başlangıcı IV İyileşme Aşamalı olarak gebelik öncesi duruma dönüş

PTD ve uzun preklinik safha ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Servikal uzunluk (SU) ,[object Object],[object Object],[object Object],[object Object]

PTD immünolojisi ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Tanı ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Lab ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Gerçek / Yalancı eylem ayrımı ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PTE altındaki muhtemel patolojiye dikkat! ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Tedavi ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Preterm vajinal doğum ihtimali varsa ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Kortikosteroidler ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Tokolitik ilaçlar ,[object Object],[object Object],[object Object],[object Object],[object Object]

Ritodrin (Prepar®) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Mg-sülfat ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Mg-sülfat YE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

İndometazin (Endol®) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Nifedipin (Nidilat®) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Nifedipin - YE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Atosiban (Tractocile®) ,[object Object],[object Object],[object Object],[object Object],[object Object]

Mevcut tokolitik tedaviler: Acı gerçekler ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Preterm EMR ,[object Object],[object Object],[object Object],[object Object]

pEMR - Tanı ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

pEMR - Takip ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

BFS ,[object Object],[object Object],[object Object],[object Object],[object Object]

pEMR Tedavi ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

PTD önlenebilir mi? ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Progesteron tedavisi ve PTD ,[object Object],[object Object],[object Object],[object Object]

Progesteron, PTD vakalarının sadece bir kısmına etki ediyor! ,[object Object],[object Object],[object Object]

PTD ve gelecek… ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Preterm doğum ve emr

Empfohlen

Empfohlen

Weitere ähnliche Inhalte

Was ist angesagt?

Was ist angesagt? (20)

Andere mochten auch

Andere mochten auch (9)

Ähnlich wie Preterm doğum ve emr

Ähnlich wie Preterm doğum ve emr (20)

Mehr von Mekin Sezik

Mehr von Mekin Sezik (9)

Preterm doğum ve emr